Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | V$E2F_Q4 |
| Enrichment Score (ES) | -0.4755278 |
| Normalized Enrichment Score (NES) | -1.7052181 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.07597542 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 511 | 0.296 | -0.0146 | No |
| 2 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 524 | 0.292 | 0.0083 | No |
| 3 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 880 | 0.210 | -0.0015 | No |
| 4 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 981 | 0.197 | 0.0069 | No |
| 5 | NELL2 | NELL2 Entrez, Source | NEL-like 2 (chicken) | 1138 | 0.178 | 0.0096 | No |
| 6 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 1225 | 0.169 | 0.0168 | No |
| 7 | EFNA5 | EFNA5 Entrez, Source | ephrin-A5 | 1498 | 0.150 | 0.0084 | No |
| 8 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 1853 | 0.129 | -0.0078 | No |
| 9 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 2146 | 0.116 | -0.0204 | No |
| 10 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 2317 | 0.110 | -0.0244 | No |
| 11 | SLC9A5 | SLC9A5 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 5 | 2614 | 0.099 | -0.0387 | No |
| 12 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 2621 | 0.098 | -0.0312 | No |
| 13 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 3194 | 0.079 | -0.0679 | No |
| 14 | CORT | CORT Entrez, Source | cortistatin | 3589 | 0.069 | -0.0921 | No |
| 15 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 3661 | 0.067 | -0.0920 | No |
| 16 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 4179 | 0.055 | -0.1265 | No |
| 17 | HTF9C | HTF9C Entrez, Source | - | 4181 | 0.055 | -0.1220 | No |
| 18 | ACO2 | ACO2 Entrez, Source | aconitase 2, mitochondrial | 4353 | 0.052 | -0.1308 | No |
| 19 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 4512 | 0.048 | -0.1388 | No |
| 20 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 4626 | 0.046 | -0.1436 | No |
| 21 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 4669 | 0.045 | -0.1431 | No |
| 22 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4801 | 0.042 | -0.1496 | No |
| 23 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 4900 | 0.040 | -0.1538 | No |
| 24 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 4925 | 0.039 | -0.1524 | No |
| 25 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 5504 | 0.028 | -0.1937 | No |
| 26 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 5597 | 0.026 | -0.1986 | No |
| 27 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 6135 | 0.016 | -0.2378 | No |
| 28 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 6264 | 0.013 | -0.2465 | No |
| 29 | UGCGL1 | UGCGL1 Entrez, Source | UDP-glucose ceramide glucosyltransferase-like 1 | 6411 | 0.009 | -0.2567 | No |
| 30 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 6650 | 0.005 | -0.2743 | No |
| 31 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 6961 | -0.001 | -0.2976 | No |
| 32 | SLC38A1 | SLC38A1 Entrez, Source | solute carrier family 38, member 1 | 7296 | -0.008 | -0.3221 | No |
| 33 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 7316 | -0.009 | -0.3228 | No |
| 34 | HCN3 | HCN3 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 | 7586 | -0.014 | -0.3420 | No |
| 35 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 8077 | -0.025 | -0.3769 | No |
| 36 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 8323 | -0.030 | -0.3930 | No |
| 37 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 8464 | -0.033 | -0.4008 | No |
| 38 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 8494 | -0.034 | -0.4002 | No |
| 39 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 8540 | -0.035 | -0.4007 | No |
| 40 | PPP1CC | PPP1CC Entrez, Source | protein phosphatase 1, catalytic subunit, gamma isoform | 8785 | -0.040 | -0.4159 | No |
| 41 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 8883 | -0.043 | -0.4197 | No |
| 42 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 8949 | -0.045 | -0.4209 | No |
| 43 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 9075 | -0.048 | -0.4265 | No |
| 44 | NCL | NCL Entrez, Source | nucleolin | 9096 | -0.049 | -0.4240 | No |
| 45 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 9128 | -0.050 | -0.4224 | No |
| 46 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 9133 | -0.050 | -0.4186 | No |
| 47 | CRK | CRK Entrez, Source | v-crk sarcoma virus CT10 oncogene homolog (avian) | 9176 | -0.051 | -0.4177 | No |
| 48 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 9231 | -0.052 | -0.4175 | No |
| 49 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 9233 | -0.052 | -0.4134 | No |
| 50 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 9351 | -0.056 | -0.4177 | No |
| 51 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 9435 | -0.058 | -0.4192 | No |
| 52 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 9560 | -0.061 | -0.4236 | No |
| 53 | RQCD1 | RQCD1 Entrez, Source | RCD1 required for cell differentiation1 homolog (S. pombe) | 9601 | -0.063 | -0.4215 | No |
| 54 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 9695 | -0.065 | -0.4233 | No |
| 55 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 10052 | -0.076 | -0.4439 | No |
| 56 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 10143 | -0.079 | -0.4443 | No |
| 57 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 10287 | -0.084 | -0.4482 | No |
| 58 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 10317 | -0.085 | -0.4435 | No |
| 59 | XTP3TPA | XTP3TPA Entrez, Source | - | 10388 | -0.088 | -0.4416 | No |
| 60 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 10473 | -0.091 | -0.4406 | No |
| 61 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 10538 | -0.093 | -0.4379 | No |
| 62 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 10651 | -0.097 | -0.4385 | No |
| 63 | RHD | RHD Entrez, Source | Rh blood group, D antigen | 10757 | -0.101 | -0.4382 | No |
| 64 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11253 | -0.124 | -0.4654 | Yes |
| 65 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 11280 | -0.126 | -0.4572 | Yes |
| 66 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 11314 | -0.127 | -0.4494 | Yes |
| 67 | NUP62 | NUP62 Entrez, Source | nucleoporin 62kDa | 11369 | -0.129 | -0.4429 | Yes |
| 68 | DCK | DCK Entrez, Source | deoxycytidine kinase | 11406 | -0.131 | -0.4350 | Yes |
| 69 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 11420 | -0.132 | -0.4252 | Yes |
| 70 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 11444 | -0.134 | -0.4161 | Yes |
| 71 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 11608 | -0.144 | -0.4167 | Yes |
| 72 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 11672 | -0.148 | -0.4094 | Yes |
| 73 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 11673 | -0.148 | -0.3974 | Yes |
| 74 | FANCD2 | FANCD2 Entrez, Source | Fanconi anemia, complementation group D2 | 11799 | -0.156 | -0.3941 | Yes |
| 75 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 11811 | -0.158 | -0.3822 | Yes |
| 76 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 11914 | -0.167 | -0.3763 | Yes |
| 77 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 12050 | -0.177 | -0.3721 | Yes |
| 78 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 12401 | -0.215 | -0.3811 | Yes |
| 79 | TMPO | TMPO Entrez, Source | thymopoietin | 12402 | -0.215 | -0.3636 | Yes |
| 80 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 12545 | -0.235 | -0.3553 | Yes |
| 81 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 12695 | -0.263 | -0.3452 | Yes |
| 82 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12897 | -0.319 | -0.3344 | Yes |
| 83 | SLCO3A1 | SLCO3A1 Entrez, Source | solute carrier organic anion transporter family, member 3A1 | 12964 | -0.345 | -0.3114 | Yes |
| 84 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 12979 | -0.351 | -0.2840 | Yes |
| 85 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13028 | -0.381 | -0.2567 | Yes |
| 86 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13077 | -0.411 | -0.2270 | Yes |
| 87 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13128 | -0.448 | -0.1944 | Yes |
| 88 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13288 | -0.823 | -0.1396 | Yes |
| 89 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13289 | -0.828 | -0.0723 | Yes |
| 90 | ABI2 | ABI2 Entrez, Source | abl interactor 2 | 13301 | -0.939 | 0.0031 | Yes |
