Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | V$E2F_Q4_01 |
| Enrichment Score (ES) | -0.4763551 |
| Normalized Enrichment Score (NES) | -1.6723434 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.085760094 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 134 | 0.557 | 0.0368 | No |
| 2 | BMP7 | BMP7 Entrez, Source | bone morphogenetic protein 7 (osteogenic protein 1) | 635 | 0.257 | 0.0208 | No |
| 3 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 1225 | 0.169 | -0.0095 | No |
| 4 | FBXO9 | FBXO9 Entrez, Source | F-box protein 9 | 1505 | 0.149 | -0.0179 | No |
| 5 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 2146 | 0.116 | -0.0564 | No |
| 6 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 2317 | 0.110 | -0.0600 | No |
| 7 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 2621 | 0.098 | -0.0746 | No |
| 8 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 2628 | 0.098 | -0.0668 | No |
| 9 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 2744 | 0.094 | -0.0675 | No |
| 10 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 3194 | 0.079 | -0.0948 | No |
| 11 | ERG | ERG Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 3255 | 0.077 | -0.0928 | No |
| 12 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 3661 | 0.067 | -0.1177 | No |
| 13 | ATP5G2 | ATP5G2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) | 3731 | 0.066 | -0.1174 | No |
| 14 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 3805 | 0.064 | -0.1175 | No |
| 15 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 4035 | 0.059 | -0.1298 | No |
| 16 | DMRT1 | DMRT1 Entrez, Source | doublesex and mab-3 related transcription factor 1 | 4088 | 0.057 | -0.1289 | No |
| 17 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 4143 | 0.056 | -0.1282 | No |
| 18 | HTF9C | HTF9C Entrez, Source | - | 4181 | 0.055 | -0.1264 | No |
| 19 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 4494 | 0.049 | -0.1458 | No |
| 20 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4801 | 0.042 | -0.1654 | No |
| 21 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 4884 | 0.040 | -0.1682 | No |
| 22 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 4925 | 0.039 | -0.1679 | No |
| 23 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 5597 | 0.026 | -0.2163 | No |
| 24 | SYT11 | SYT11 Entrez, Source | synaptotagmin XI | 6102 | 0.016 | -0.2530 | No |
| 25 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 6115 | 0.016 | -0.2525 | No |
| 26 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 6135 | 0.016 | -0.2527 | No |
| 27 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 6264 | 0.013 | -0.2613 | No |
| 28 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 6466 | 0.008 | -0.2757 | No |
| 29 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 6650 | 0.005 | -0.2891 | No |
| 30 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 6869 | 0.001 | -0.3055 | No |
| 31 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 6961 | -0.001 | -0.3122 | No |
| 32 | NEGR1 | NEGR1 Entrez, Source | neuronal growth regulator 1 | 7019 | -0.003 | -0.3163 | No |
| 33 | IMPDH2 | IMPDH2 Entrez, Source | IMP (inosine monophosphate) dehydrogenase 2 | 7268 | -0.008 | -0.3344 | No |
| 34 | SLC38A1 | SLC38A1 Entrez, Source | solute carrier family 38, member 1 | 7296 | -0.008 | -0.3357 | No |
| 35 | SFMBT1 | SFMBT1 Entrez, Source | Scm-like with four mbt domains 1 | 7686 | -0.016 | -0.3637 | No |
| 36 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 8077 | -0.025 | -0.3910 | No |
| 37 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 8323 | -0.030 | -0.4069 | No |
| 38 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 8494 | -0.034 | -0.4169 | No |
| 39 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 8540 | -0.035 | -0.4173 | No |
| 40 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 8679 | -0.039 | -0.4244 | No |
| 41 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 8707 | -0.039 | -0.4232 | No |
| 42 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 8883 | -0.043 | -0.4327 | No |
| 43 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 8949 | -0.045 | -0.4339 | No |
| 44 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 8981 | -0.045 | -0.4324 | No |
| 45 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 9082 | -0.048 | -0.4359 | No |
| 46 | NCL | NCL Entrez, Source | nucleolin | 9096 | -0.049 | -0.4328 | No |
| 47 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 9133 | -0.050 | -0.4313 | No |
| 48 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 9231 | -0.052 | -0.4342 | No |
| 49 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 9233 | -0.052 | -0.4299 | No |
| 50 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 9351 | -0.056 | -0.4340 | No |
| 51 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 9357 | -0.056 | -0.4297 | No |
| 52 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 9435 | -0.058 | -0.4306 | No |
| 53 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 9441 | -0.058 | -0.4261 | No |
| 54 | DIO3 | DIO3 Entrez, Source | deiodinase, iodothyronine, type III | 9522 | -0.060 | -0.4270 | No |
| 55 | PIK3R3 | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 9602 | -0.063 | -0.4277 | No |
| 56 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 9861 | -0.070 | -0.4413 | No |
| 57 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 10143 | -0.079 | -0.4558 | No |
| 58 | NR3C2 | NR3C2 Entrez, Source | nuclear receptor subfamily 3, group C, member 2 | 10284 | -0.084 | -0.4593 | No |
| 59 | NCOA6 | NCOA6 Entrez, Source | nuclear receptor coactivator 6 | 10335 | -0.086 | -0.4558 | No |
| 60 | XTP3TPA | XTP3TPA Entrez, Source | - | 10388 | -0.088 | -0.4523 | No |
| 61 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 10400 | -0.088 | -0.4457 | No |
| 62 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 10538 | -0.093 | -0.4482 | No |
| 63 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 10651 | -0.097 | -0.4485 | No |
| 64 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 10774 | -0.102 | -0.4491 | No |
| 65 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 10892 | -0.106 | -0.4490 | No |
| 66 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 11087 | -0.116 | -0.4539 | No |
| 67 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11253 | -0.124 | -0.4559 | No |
| 68 | DCK | DCK Entrez, Source | deoxycytidine kinase | 11406 | -0.131 | -0.4563 | No |
| 69 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 11673 | -0.148 | -0.4639 | Yes |
| 70 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 11774 | -0.155 | -0.4584 | Yes |
| 71 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 11811 | -0.158 | -0.4478 | Yes |
| 72 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 11914 | -0.167 | -0.4415 | Yes |
| 73 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 12047 | -0.177 | -0.4365 | Yes |
| 74 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 12130 | -0.184 | -0.4272 | Yes |
| 75 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 12545 | -0.235 | -0.4386 | Yes |
| 76 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 12695 | -0.263 | -0.4278 | Yes |
| 77 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12897 | -0.319 | -0.4160 | Yes |
| 78 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12999 | -0.364 | -0.3930 | Yes |
| 79 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13028 | -0.381 | -0.3631 | Yes |
| 80 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 13032 | -0.382 | -0.3311 | Yes |
| 81 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13077 | -0.411 | -0.2998 | Yes |
| 82 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 13120 | -0.443 | -0.2657 | Yes |
| 83 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13128 | -0.448 | -0.2285 | Yes |
| 84 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 13202 | -0.565 | -0.1864 | Yes |
| 85 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13252 | -0.684 | -0.1325 | Yes |
| 86 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13288 | -0.823 | -0.0658 | Yes |
| 87 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13289 | -0.828 | 0.0040 | Yes |
