Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | V$E2F_Q6_01 |
| Enrichment Score (ES) | -0.5585859 |
| Normalized Enrichment Score (NES) | -1.9508805 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.015247927 |
| FWER p-Value | 0.252 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | BMP7 | BMP7 Entrez, Source | bone morphogenetic protein 7 (osteogenic protein 1) | 635 | 0.257 | -0.0264 | No |
| 2 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 2146 | 0.116 | -0.1305 | No |
| 3 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 2317 | 0.110 | -0.1342 | No |
| 4 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 2621 | 0.098 | -0.1488 | No |
| 5 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 2628 | 0.098 | -0.1411 | No |
| 6 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 2744 | 0.094 | -0.1419 | No |
| 7 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 3194 | 0.079 | -0.1692 | No |
| 8 | ERG | ERG Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 3255 | 0.077 | -0.1673 | No |
| 9 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 3661 | 0.067 | -0.1922 | No |
| 10 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 3805 | 0.064 | -0.1976 | No |
| 11 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 4035 | 0.059 | -0.2100 | No |
| 12 | BARHL1 | BARHL1 Entrez, Source | BarH-like 1 (Drosophila) | 4059 | 0.058 | -0.2068 | No |
| 13 | DMRT1 | DMRT1 Entrez, Source | doublesex and mab-3 related transcription factor 1 | 4088 | 0.057 | -0.2042 | No |
| 14 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 4143 | 0.056 | -0.2035 | No |
| 15 | HTF9C | HTF9C Entrez, Source | - | 4181 | 0.055 | -0.2017 | No |
| 16 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 4512 | 0.048 | -0.2225 | No |
| 17 | KLHDC3 | KLHDC3 Entrez, Source | kelch domain containing 3 | 4632 | 0.046 | -0.2277 | No |
| 18 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 4742 | 0.043 | -0.2323 | No |
| 19 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4801 | 0.042 | -0.2332 | No |
| 20 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 4884 | 0.040 | -0.2360 | No |
| 21 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 4925 | 0.039 | -0.2358 | No |
| 22 | CACNA1G | CACNA1G Entrez, Source | calcium channel, voltage-dependent, alpha 1G subunit | 5281 | 0.032 | -0.2599 | No |
| 23 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 5597 | 0.026 | -0.2815 | No |
| 24 | HTR2C | HTR2C Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2C | 5945 | 0.019 | -0.3060 | No |
| 25 | SNCB | SNCB Entrez, Source | synuclein, beta | 5952 | 0.019 | -0.3049 | No |
| 26 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 6115 | 0.016 | -0.3158 | No |
| 27 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 6135 | 0.016 | -0.3159 | No |
| 28 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 6264 | 0.013 | -0.3245 | No |
| 29 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 6466 | 0.008 | -0.3389 | No |
| 30 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 6650 | 0.005 | -0.3523 | No |
| 31 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 6961 | -0.001 | -0.3756 | No |
| 32 | SFMBT1 | SFMBT1 Entrez, Source | Scm-like with four mbt domains 1 | 7686 | -0.016 | -0.4289 | No |
| 33 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 8077 | -0.025 | -0.4562 | No |
| 34 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 8323 | -0.030 | -0.4721 | No |
| 35 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 8494 | -0.034 | -0.4821 | No |
| 36 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 8540 | -0.035 | -0.4825 | No |
| 37 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 8679 | -0.039 | -0.4897 | No |
| 38 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 8707 | -0.039 | -0.4885 | No |
| 39 | ACIN1 | ACIN1 Entrez, Source | apoptotic chromatin condensation inducer 1 | 8761 | -0.040 | -0.4891 | No |
| 40 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 8883 | -0.043 | -0.4946 | No |
| 41 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 8949 | -0.045 | -0.4958 | No |
| 42 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 8981 | -0.045 | -0.4943 | No |
| 43 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 9082 | -0.048 | -0.4979 | No |
| 44 | NCL | NCL Entrez, Source | nucleolin | 9096 | -0.049 | -0.4948 | No |
| 45 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 9133 | -0.050 | -0.4933 | No |
| 46 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 9231 | -0.052 | -0.4963 | No |
| 47 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 9357 | -0.056 | -0.5010 | No |
| 48 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 9435 | -0.058 | -0.5020 | No |
| 49 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 9477 | -0.059 | -0.5001 | No |
| 50 | SIAHBP1 | SIAHBP1 Entrez, Source | - | 9746 | -0.066 | -0.5148 | No |
| 51 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 9861 | -0.070 | -0.5175 | No |
| 52 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 10143 | -0.079 | -0.5321 | No |
| 53 | XTP3TPA | XTP3TPA Entrez, Source | - | 10388 | -0.088 | -0.5431 | No |
| 54 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 10400 | -0.088 | -0.5366 | No |
| 55 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 10538 | -0.093 | -0.5392 | No |
| 56 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 10651 | -0.097 | -0.5395 | No |
| 57 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 10774 | -0.102 | -0.5402 | No |
| 58 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 10892 | -0.106 | -0.5401 | No |
| 59 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 11087 | -0.116 | -0.5451 | No |
| 60 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11253 | -0.124 | -0.5471 | No |
| 61 | DCK | DCK Entrez, Source | deoxycytidine kinase | 11406 | -0.131 | -0.5476 | Yes |
| 62 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 11492 | -0.137 | -0.5426 | Yes |
| 63 | RALY | RALY Entrez, Source | RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) | 11665 | -0.148 | -0.5432 | Yes |
| 64 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 11672 | -0.148 | -0.5312 | Yes |
| 65 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 11673 | -0.148 | -0.5188 | Yes |
| 66 | DUSP7 | DUSP7 Entrez, Source | dual specificity phosphatase 7 | 11765 | -0.153 | -0.5129 | Yes |
| 67 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 11774 | -0.155 | -0.5005 | Yes |
| 68 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 11811 | -0.158 | -0.4901 | Yes |
| 69 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 11914 | -0.167 | -0.4838 | Yes |
| 70 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 12130 | -0.184 | -0.4847 | Yes |
| 71 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 12163 | -0.188 | -0.4714 | Yes |
| 72 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 12545 | -0.235 | -0.4805 | Yes |
| 73 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 12692 | -0.262 | -0.4695 | Yes |
| 74 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 12695 | -0.263 | -0.4477 | Yes |
| 75 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 12767 | -0.278 | -0.4299 | Yes |
| 76 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12897 | -0.319 | -0.4129 | Yes |
| 77 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12999 | -0.364 | -0.3901 | Yes |
| 78 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13028 | -0.381 | -0.3603 | Yes |
| 79 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 13032 | -0.382 | -0.3286 | Yes |
| 80 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13077 | -0.411 | -0.2976 | Yes |
| 81 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 13120 | -0.443 | -0.2637 | Yes |
| 82 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13128 | -0.448 | -0.2268 | Yes |
| 83 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 13202 | -0.565 | -0.1850 | Yes |
| 84 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13252 | -0.684 | -0.1315 | Yes |
| 85 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13288 | -0.823 | -0.0653 | Yes |
| 86 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13289 | -0.828 | 0.0040 | Yes |
