Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | V$GR_Q6_01 |
| Enrichment Score (ES) | -0.48831648 |
| Normalized Enrichment Score (NES) | -1.7834557 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.053182494 |
| FWER p-Value | 0.951 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | WNT4 | WNT4 Entrez, Source | wingless-type MMTV integration site family, member 4 | 51 | 0.748 | 0.0408 | No |
| 2 | CSNK1G1 | CSNK1G1 Entrez, Source | casein kinase 1, gamma 1 | 498 | 0.300 | 0.0250 | No |
| 3 | SLC25A10 | SLC25A10 Entrez, Source | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | 642 | 0.255 | 0.0294 | No |
| 4 | SV2B | SV2B Entrez, Source | synaptic vesicle glycoprotein 2B | 1251 | 0.167 | -0.0066 | No |
| 5 | PROK2 | PROK2 Entrez, Source | prokineticin 2 | 1261 | 0.167 | 0.0027 | No |
| 6 | AQP4 | AQP4 Entrez, Source | aquaporin 4 | 1360 | 0.160 | 0.0049 | No |
| 7 | C6ORF66 | C6ORF66 Entrez, Source | chromosome 6 open reading frame 66 | 1532 | 0.147 | 0.0007 | No |
| 8 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1535 | 0.147 | 0.0093 | No |
| 9 | KCNK10 | KCNK10 Entrez, Source | potassium channel, subfamily K, member 10 | 1613 | 0.142 | 0.0120 | No |
| 10 | SYT6 | SYT6 Entrez, Source | synaptotagmin VI | 1748 | 0.134 | 0.0099 | No |
| 11 | OTX2 | OTX2 Entrez, Source | orthodenticle homolog 2 (Drosophila) | 1795 | 0.131 | 0.0142 | No |
| 12 | MPZ | MPZ Entrez, Source | myelin protein zero (Charcot-Marie-Tooth neuropathy 1B) | 1802 | 0.131 | 0.0216 | No |
| 13 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 2102 | 0.118 | 0.0060 | No |
| 14 | TNNT3 | TNNT3 Entrez, Source | troponin T type 3 (skeletal, fast) | 2118 | 0.117 | 0.0119 | No |
| 15 | SLC38A2 | SLC38A2 Entrez, Source | solute carrier family 38, member 2 | 2153 | 0.116 | 0.0162 | No |
| 16 | APBA1 | APBA1 Entrez, Source | amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) | 2378 | 0.108 | 0.0057 | No |
| 17 | CDH2 | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 2409 | 0.106 | 0.0098 | No |
| 18 | SULT2A1 | SULT2A1 Entrez, Source | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 2731 | 0.094 | -0.0088 | No |
| 19 | EYA2 | EYA2 Entrez, Source | eyes absent homolog 2 (Drosophila) | 2749 | 0.094 | -0.0045 | No |
| 20 | HOXA2 | HOXA2 Entrez, Source | homeobox A2 | 2766 | 0.093 | -0.0002 | No |
| 21 | PCDH8 | PCDH8 Entrez, Source | protocadherin 8 | 2869 | 0.089 | -0.0026 | No |
| 22 | CPA3 | CPA3 Entrez, Source | carboxypeptidase A3 (mast cell) | 2949 | 0.087 | -0.0034 | No |
| 23 | SLC2A2 | SLC2A2 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 2 | 2969 | 0.086 | 0.0003 | No |
| 24 | LRRN6A | LRRN6A Entrez, Source | leucine rich repeat neuronal 6A | 3025 | 0.084 | 0.0012 | No |
| 25 | OTX1 | OTX1 Entrez, Source | orthodenticle homolog 1 (Drosophila) | 3094 | 0.082 | 0.0009 | No |
| 26 | LTBP3 | LTBP3 Entrez, Source | latent transforming growth factor beta binding protein 3 | 3276 | 0.077 | -0.0082 | No |
| 27 | FANK1 | FANK1 Entrez, Source | fibronectin type III and ankyrin repeat domains 1 | 3292 | 0.076 | -0.0048 | No |
| 28 | TNMD | TNMD Entrez, Source | tenomodulin | 3422 | 0.073 | -0.0101 | No |
| 29 | ARG2 | ARG2 Entrez, Source | arginase, type II | 3449 | 0.072 | -0.0078 | No |
| 30 | PPM1B | PPM1B Entrez, Source | protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform | 3600 | 0.069 | -0.0150 | No |
| 31 | SLC18A3 | SLC18A3 Entrez, Source | solute carrier family 18 (vesicular acetylcholine), member 3 | 3741 | 0.065 | -0.0217 | No |
| 32 | NOG | NOG Entrez, Source | noggin | 3747 | 0.065 | -0.0182 | No |
| 33 | EPHA7 | EPHA7 Entrez, Source | EPH receptor A7 | 4393 | 0.051 | -0.0639 | No |
| 34 | OPN1SW | OPN1SW Entrez, Source | opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) | 4652 | 0.045 | -0.0807 | No |
| 35 | GMPR2 | GMPR2 Entrez, Source | guanosine monophosphate reductase 2 | 4705 | 0.044 | -0.0820 | No |
| 36 | SCNN1A | SCNN1A Entrez, Source | sodium channel, nonvoltage-gated 1 alpha | 4857 | 0.041 | -0.0910 | No |
| 37 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 4898 | 0.040 | -0.0917 | No |
| 38 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 5204 | 0.034 | -0.1127 | No |
| 39 | MYH4 | MYH4 Entrez, Source | myosin, heavy chain 4, skeletal muscle | 5810 | 0.022 | -0.1571 | No |
| 40 | LGI1 | LGI1 Entrez, Source | leucine-rich, glioma inactivated 1 | 5982 | 0.019 | -0.1689 | No |
| 41 | ANK3 | ANK3 Entrez, Source | ankyrin 3, node of Ranvier (ankyrin G) | 6084 | 0.017 | -0.1755 | No |
| 42 | ABCG8 | ABCG8 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2) | 6099 | 0.016 | -0.1756 | No |
| 43 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 6135 | 0.016 | -0.1773 | No |
| 44 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 6146 | 0.015 | -0.1772 | No |
| 45 | MRPS18B | MRPS18B Entrez, Source | mitochondrial ribosomal protein S18B | 6292 | 0.012 | -0.1874 | No |
| 46 | PAX3 | PAX3 Entrez, Source | paired box gene 3 (Waardenburg syndrome 1) | 6318 | 0.012 | -0.1886 | No |
| 47 | PDYN | PDYN Entrez, Source | prodynorphin | 6886 | 0.001 | -0.2314 | No |
| 48 | PSEN1 | PSEN1 Entrez, Source | presenilin 1 (Alzheimer disease 3) | 6918 | -0.000 | -0.2337 | No |
| 49 | FGD4 | FGD4 Entrez, Source | FYVE, RhoGEF and PH domain containing 4 | 6928 | -0.000 | -0.2344 | No |
| 50 | RND1 | RND1 Entrez, Source | Rho family GTPase 1 | 6944 | -0.001 | -0.2355 | No |
| 51 | GRP | GRP Entrez, Source | gastrin-releasing peptide | 7119 | -0.004 | -0.2484 | No |
| 52 | TMEM24 | TMEM24 Entrez, Source | transmembrane protein 24 | 7510 | -0.013 | -0.2771 | No |
| 53 | ZP3 | ZP3 Entrez, Source | zona pellucida glycoprotein 3 (sperm receptor) | 7546 | -0.013 | -0.2789 | No |
| 54 | NCDN | NCDN Entrez, Source | neurochondrin | 8196 | -0.027 | -0.3263 | No |
| 55 | MAGED1 | MAGED1 Entrez, Source | melanoma antigen family D, 1 | 8492 | -0.034 | -0.3466 | No |
| 56 | PDAP1 | PDAP1 Entrez, Source | PDGFA associated protein 1 | 8528 | -0.035 | -0.3471 | No |
| 57 | ST13 | ST13 Entrez, Source | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 8530 | -0.035 | -0.3451 | No |
| 58 | BAT4 | BAT4 Entrez, Source | HLA-B associated transcript 4 | 8687 | -0.039 | -0.3546 | No |
| 59 | NPEPPS | NPEPPS Entrez, Source | aminopeptidase puromycin sensitive | 8805 | -0.041 | -0.3610 | No |
| 60 | AKAP5 | AKAP5 Entrez, Source | A kinase (PRKA) anchor protein 5 | 8896 | -0.043 | -0.3652 | No |
| 61 | EFNA1 | EFNA1 Entrez, Source | ephrin-A1 | 8967 | -0.045 | -0.3678 | No |
| 62 | DND1 | DND1 Entrez, Source | dead end homolog 1 (zebrafish) | 9103 | -0.049 | -0.3751 | No |
| 63 | RBX1 | RBX1 Entrez, Source | ring-box 1 | 9418 | -0.058 | -0.3953 | No |
| 64 | AKAP7 | AKAP7 Entrez, Source | A kinase (PRKA) anchor protein 7 | 9533 | -0.061 | -0.4003 | No |
| 65 | TGIF | TGIF Entrez, Source | TGFB-induced factor (TALE family homeobox) | 9563 | -0.061 | -0.3989 | No |
| 66 | SIX1 | SIX1 Entrez, Source | sine oculis homeobox homolog 1 (Drosophila) | 9691 | -0.065 | -0.4046 | No |
| 67 | SDC1 | SDC1 Entrez, Source | syndecan 1 | 9762 | -0.067 | -0.4059 | No |
| 68 | NEDD8 | NEDD8 Entrez, Source | neural precursor cell expressed, developmentally down-regulated 8 | 9792 | -0.068 | -0.4040 | No |
| 69 | EIF2B4 | EIF2B4 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa | 10082 | -0.077 | -0.4212 | No |
| 70 | NCOA3 | NCOA3 Entrez, Source | nuclear receptor coactivator 3 | 10363 | -0.087 | -0.4372 | No |
| 71 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 10473 | -0.091 | -0.4400 | No |
| 72 | EIF4G2 | EIF4G2 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 2 | 10707 | -0.099 | -0.4517 | No |
| 73 | KLHL5 | KLHL5 Entrez, Source | kelch-like 5 (Drosophila) | 11028 | -0.113 | -0.4692 | No |
| 74 | CAMLG | CAMLG Entrez, Source | calcium modulating ligand | 11201 | -0.121 | -0.4749 | No |
| 75 | PACSIN3 | PACSIN3 Entrez, Source | protein kinase C and casein kinase substrate in neurons 3 | 11342 | -0.128 | -0.4778 | No |
| 76 | ITPR3 | ITPR3 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 3 | 11479 | -0.136 | -0.4800 | Yes |
| 77 | PPP1R10 | PPP1R10 Entrez, Source | protein phosphatase 1, regulatory subunit 10 | 11590 | -0.143 | -0.4798 | Yes |
| 78 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 11630 | -0.145 | -0.4741 | Yes |
| 79 | PLSCR3 | PLSCR3 Entrez, Source | phospholipid scramblase 3 | 11681 | -0.149 | -0.4690 | Yes |
| 80 | PXN | PXN Entrez, Source | paxillin | 11831 | -0.159 | -0.4708 | Yes |
| 81 | FOXA1 | FOXA1 Entrez, Source | forkhead box A1 | 11900 | -0.165 | -0.4660 | Yes |
| 82 | TCN2 | TCN2 Entrez, Source | transcobalamin II; macrocytic anemia | 11922 | -0.167 | -0.4576 | Yes |
| 83 | RTKN | RTKN Entrez, Source | rhotekin | 11968 | -0.170 | -0.4509 | Yes |
| 84 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 12050 | -0.177 | -0.4464 | Yes |
| 85 | KHDRBS1 | KHDRBS1 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 1 | 12056 | -0.178 | -0.4362 | Yes |
| 86 | ZNF24 | ZNF24 Entrez, Source | zinc finger protein 24 | 12108 | -0.182 | -0.4292 | Yes |
| 87 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 12177 | -0.189 | -0.4230 | Yes |
| 88 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 12251 | -0.199 | -0.4167 | Yes |
| 89 | MASP1 | MASP1 Entrez, Source | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) | 12320 | -0.207 | -0.4095 | Yes |
| 90 | SNX17 | SNX17 Entrez, Source | sorting nexin 17 | 12348 | -0.210 | -0.3990 | Yes |
| 91 | LASP1 | LASP1 Entrez, Source | LIM and SH3 protein 1 | 12412 | -0.216 | -0.3908 | Yes |
| 92 | EP300 | EP300 Entrez, Source | E1A binding protein p300 | 12496 | -0.228 | -0.3835 | Yes |
| 93 | QKI | QKI Entrez, Source | quaking homolog, KH domain RNA binding (mouse) | 12675 | -0.260 | -0.3814 | Yes |
| 94 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 12720 | -0.269 | -0.3687 | Yes |
| 95 | GCNT3 | GCNT3 Entrez, Source | glucosaminyl (N-acetyl) transferase 3, mucin type | 12742 | -0.273 | -0.3540 | Yes |
| 96 | JMJD1C | JMJD1C Entrez, Source | jumonji domain containing 1C | 12770 | -0.278 | -0.3394 | Yes |
| 97 | ETS1 | ETS1 Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 12786 | -0.282 | -0.3237 | Yes |
| 98 | SF3B4 | SF3B4 Entrez, Source | splicing factor 3b, subunit 4, 49kDa | 12871 | -0.309 | -0.3116 | Yes |
| 99 | SCHIP1 | SCHIP1 Entrez, Source | schwannomin interacting protein 1 | 12910 | -0.326 | -0.2950 | Yes |
| 100 | MAP1B | MAP1B Entrez, Source | microtubule-associated protein 1B | 12944 | -0.337 | -0.2774 | Yes |
| 101 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12998 | -0.364 | -0.2597 | Yes |
| 102 | DHX40 | DHX40 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 13019 | -0.376 | -0.2388 | Yes |
| 103 | GPM6A | GPM6A Entrez, Source | glycoprotein M6A | 13153 | -0.485 | -0.2199 | Yes |
| 104 | DOK1 | DOK1 Entrez, Source | docking protein 1, 62kDa (downstream of tyrosine kinase 1) | 13216 | -0.591 | -0.1893 | Yes |
| 105 | PPP2R3A | PPP2R3A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha | 13267 | -0.745 | -0.1486 | Yes |
| 106 | MMP11 | MMP11 Entrez, Source | matrix metallopeptidase 11 (stromelysin 3) | 13273 | -0.768 | -0.1032 | Yes |
| 107 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13288 | -0.823 | -0.0552 | Yes |
| 108 | LOX | LOX Entrez, Source | lysyl oxidase | 13308 | -0.991 | 0.0026 | Yes |
