Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | V$SREBP1_01 |
| Enrichment Score (ES) | -0.5779787 |
| Normalized Enrichment Score (NES) | -1.9915731 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.008788822 |
| FWER p-Value | 0.13 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 524 | 0.292 | -0.0106 | No |
| 2 | DSCAM | DSCAM Entrez, Source | Down syndrome cell adhesion molecule | 2452 | 0.105 | -0.1455 | No |
| 3 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 2527 | 0.102 | -0.1410 | No |
| 4 | HOXA2 | HOXA2 Entrez, Source | homeobox A2 | 2766 | 0.093 | -0.1498 | No |
| 5 | CANX | CANX Entrez, Source | calnexin | 2961 | 0.086 | -0.1559 | No |
| 6 | SNAI1 | SNAI1 Entrez, Source | snail homolog 1 (Drosophila) | 3621 | 0.068 | -0.1988 | No |
| 7 | PRKCE | PRKCE Entrez, Source | protein kinase C, epsilon | 4038 | 0.059 | -0.2244 | No |
| 8 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 5084 | 0.036 | -0.2995 | No |
| 9 | SNRPA | SNRPA Entrez, Source | small nuclear ribonucleoprotein polypeptide A | 5088 | 0.036 | -0.2962 | No |
| 10 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 5266 | 0.032 | -0.3063 | No |
| 11 | UBE2B | UBE2B Entrez, Source | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 5274 | 0.032 | -0.3036 | No |
| 12 | SEPT3 | SEPT3 Entrez, Source | septin 3 | 5363 | 0.031 | -0.3072 | No |
| 13 | SLC36A1 | SLC36A1 Entrez, Source | solute carrier family 36 (proton/amino acid symporter), member 1 | 5594 | 0.026 | -0.3220 | No |
| 14 | SOX10 | SOX10 Entrez, Source | SRY (sex determining region Y)-box 10 | 5991 | 0.018 | -0.3500 | No |
| 15 | ACCN1 | ACCN1 Entrez, Source | amiloride-sensitive cation channel 1, neuronal (degenerin) | 6344 | 0.011 | -0.3755 | No |
| 16 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 6399 | 0.010 | -0.3786 | No |
| 17 | ADCY2 | ADCY2 Entrez, Source | adenylate cyclase 2 (brain) | 6634 | 0.005 | -0.3957 | No |
| 18 | QTRT1 | QTRT1 Entrez, Source | queuine tRNA-ribosyltransferase 1 (tRNA-guanine transglycosylase) | 6643 | 0.005 | -0.3958 | No |
| 19 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 6686 | 0.004 | -0.3985 | No |
| 20 | HK2 | HK2 Entrez, Source | hexokinase 2 | 6922 | -0.000 | -0.4162 | No |
| 21 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 7521 | -0.013 | -0.4600 | No |
| 22 | HSPBAP1 | HSPBAP1 Entrez, Source | HSPB (heat shock 27kDa) associated protein 1 | 7879 | -0.020 | -0.4849 | No |
| 23 | ATP6V0D1 | ATP6V0D1 Entrez, Source | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 | 7916 | -0.021 | -0.4855 | No |
| 24 | PIAS4 | PIAS4 Entrez, Source | protein inhibitor of activated STAT, 4 | 8140 | -0.026 | -0.4997 | No |
| 25 | DAZAP2 | DAZAP2 Entrez, Source | DAZ associated protein 2 | 8158 | -0.027 | -0.4983 | No |
| 26 | AARS | AARS Entrez, Source | alanyl-tRNA synthetase | 8177 | -0.027 | -0.4970 | No |
| 27 | DIRC2 | DIRC2 Entrez, Source | disrupted in renal carcinoma 2 | 8205 | -0.028 | -0.4963 | No |
| 28 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 8782 | -0.040 | -0.5357 | No |
| 29 | GGN | GGN Entrez, Source | gametogenetin | 9072 | -0.048 | -0.5528 | No |
| 30 | TRPM7 | TRPM7 Entrez, Source | transient receptor potential cation channel, subfamily M, member 7 | 9127 | -0.049 | -0.5519 | No |
| 31 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 9141 | -0.050 | -0.5480 | No |
| 32 | ASNA1 | ASNA1 Entrez, Source | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) | 9162 | -0.050 | -0.5445 | No |
| 33 | CUL5 | CUL5 Entrez, Source | cullin 5 | 9220 | -0.052 | -0.5437 | No |
| 34 | POLR3C | POLR3C Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide C (62kD) | 9462 | -0.059 | -0.5561 | No |
| 35 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 9496 | -0.060 | -0.5527 | No |
| 36 | MYST2 | MYST2 Entrez, Source | MYST histone acetyltransferase 2 | 9697 | -0.065 | -0.5613 | No |
| 37 | ATP7A | ATP7A Entrez, Source | ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome) | 9722 | -0.066 | -0.5567 | No |
| 38 | ZDHHC13 | ZDHHC13 Entrez, Source | zinc finger, DHHC-type containing 13 | 9830 | -0.069 | -0.5579 | No |
| 39 | PDCD6IP | PDCD6IP Entrez, Source | programmed cell death 6 interacting protein | 9842 | -0.070 | -0.5518 | No |
| 40 | LAMP1 | LAMP1 Entrez, Source | lysosomal-associated membrane protein 1 | 9876 | -0.070 | -0.5474 | No |
| 41 | GNB2 | GNB2 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 10152 | -0.080 | -0.5602 | No |
| 42 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 10193 | -0.081 | -0.5552 | No |
| 43 | HTATIP | HTATIP Entrez, Source | HIV-1 Tat interacting protein, 60kDa | 10248 | -0.083 | -0.5511 | No |
| 44 | APEX1 | APEX1 Entrez, Source | APEX nuclease (multifunctional DNA repair enzyme) 1 | 10323 | -0.086 | -0.5482 | No |
| 45 | CBARA1 | CBARA1 Entrez, Source | calcium binding atopy-related autoantigen 1 | 10356 | -0.087 | -0.5421 | No |
| 46 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 10369 | -0.087 | -0.5344 | No |
| 47 | BAX | BAX Entrez, Source | BCL2-associated X protein | 10699 | -0.098 | -0.5494 | No |
| 48 | COMMD3 | COMMD3 Entrez, Source | COMM domain containing 3 | 10982 | -0.111 | -0.5597 | No |
| 49 | RAB3A | RAB3A Entrez, Source | RAB3A, member RAS oncogene family | 11225 | -0.123 | -0.5658 | Yes |
| 50 | RNF146 | RNF146 Entrez, Source | ring finger protein 146 | 11245 | -0.124 | -0.5550 | Yes |
| 51 | OSGEP | OSGEP Entrez, Source | O-sialoglycoprotein endopeptidase | 11295 | -0.126 | -0.5463 | Yes |
| 52 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 11315 | -0.127 | -0.5351 | Yes |
| 53 | PIP5K1A | PIP5K1A Entrez, Source | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 11601 | -0.144 | -0.5424 | Yes |
| 54 | BLNK | BLNK Entrez, Source | B-cell linker | 11704 | -0.150 | -0.5353 | Yes |
| 55 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 11725 | -0.151 | -0.5220 | Yes |
| 56 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 11850 | -0.160 | -0.5155 | Yes |
| 57 | SUPT6H | SUPT6H Entrez, Source | suppressor of Ty 6 homolog (S. cerevisiae) | 12129 | -0.184 | -0.5183 | Yes |
| 58 | LCP1 | LCP1 Entrez, Source | lymphocyte cytosolic protein 1 (L-plastin) | 12308 | -0.205 | -0.5114 | Yes |
| 59 | STX6 | STX6 Entrez, Source | syntaxin 6 | 12357 | -0.211 | -0.4942 | Yes |
| 60 | SNX16 | SNX16 Entrez, Source | sorting nexin 16 | 12373 | -0.212 | -0.4744 | Yes |
| 61 | FMR1 | FMR1 Entrez, Source | fragile X mental retardation 1 | 12443 | -0.220 | -0.4579 | Yes |
| 62 | DCTN4 | DCTN4 Entrez, Source | dynactin 4 (p62) | 12513 | -0.230 | -0.4403 | Yes |
| 63 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 12720 | -0.269 | -0.4293 | Yes |
| 64 | CBX6 | CBX6 Entrez, Source | chromobox homolog 6 | 12906 | -0.325 | -0.4111 | Yes |
| 65 | GRN | GRN Entrez, Source | granulin | 12920 | -0.329 | -0.3796 | Yes |
| 66 | CAMK2D | CAMK2D Entrez, Source | calcium/calmodulin-dependent protein kinase (CaM kinase) II delta | 13042 | -0.390 | -0.3503 | Yes |
| 67 | NGFRAP1 | NGFRAP1 Entrez, Source | nerve growth factor receptor (TNFRSF16) associated protein 1 | 13127 | -0.447 | -0.3125 | Yes |
| 68 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 13183 | -0.530 | -0.2642 | Yes |
| 69 | GPNMB | GPNMB Entrez, Source | glycoprotein (transmembrane) nmb | 13207 | -0.576 | -0.2091 | Yes |
| 70 | BEX1 | BEX1 Entrez, Source | brain expressed, X-linked 1 | 13225 | -0.617 | -0.1495 | Yes |
| 71 | TCEAL1 | TCEAL1 Entrez, Source | transcription elongation factor A (SII)-like 1 | 13276 | -0.778 | -0.0764 | Yes |
| 72 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13288 | -0.823 | 0.0041 | Yes |
