Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | V$SRF_C |
| Enrichment Score (ES) | -0.52306664 |
| Normalized Enrichment Score (NES) | -1.8942654 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.022857375 |
| FWER p-Value | 0.494 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 299 | 0.398 | -0.0026 | No |
| 2 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 383 | 0.346 | 0.0084 | No |
| 3 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 402 | 0.338 | 0.0240 | No |
| 4 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 470 | 0.312 | 0.0345 | No |
| 5 | RAB30 | RAB30 Entrez, Source | RAB30, member RAS oncogene family | 545 | 0.284 | 0.0432 | No |
| 6 | IER2 | IER2 Entrez, Source | immediate early response 2 | 634 | 0.257 | 0.0494 | No |
| 7 | EGR1 | EGR1 Entrez, Source | early growth response 1 | 795 | 0.221 | 0.0484 | No |
| 8 | ZFHX1B | ZFHX1B Entrez, Source | zinc finger homeobox 1b | 883 | 0.209 | 0.0523 | No |
| 9 | ASPA | ASPA Entrez, Source | aspartoacylase (Canavan disease) | 1027 | 0.189 | 0.0509 | No |
| 10 | RNF39 | RNF39 Entrez, Source | ring finger protein 39 | 1091 | 0.183 | 0.0553 | No |
| 11 | KCNK3 | KCNK3 Entrez, Source | potassium channel, subfamily K, member 3 | 1094 | 0.183 | 0.0643 | No |
| 12 | EGR4 | EGR4 Entrez, Source | early growth response 4 | 1292 | 0.165 | 0.0577 | No |
| 13 | MBNL1 | MBNL1 Entrez, Source | muscleblind-like (Drosophila) | 1343 | 0.161 | 0.0620 | No |
| 14 | TNNC1 | TNNC1 Entrez, Source | troponin C type 1 (slow) | 1752 | 0.134 | 0.0379 | No |
| 15 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 2146 | 0.116 | 0.0140 | No |
| 16 | RGS3 | RGS3 Entrez, Source | regulator of G-protein signalling 3 | 2542 | 0.101 | -0.0108 | No |
| 17 | IL17B | IL17B Entrez, Source | interleukin 17B | 2561 | 0.101 | -0.0071 | No |
| 18 | MYO1B | MYO1B Entrez, Source | myosin IB | 2569 | 0.100 | -0.0026 | No |
| 19 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 2621 | 0.098 | -0.0015 | No |
| 20 | POU3F4 | POU3F4 Entrez, Source | POU domain, class 3, transcription factor 4 | 2699 | 0.095 | -0.0026 | No |
| 21 | CACNA1B | CACNA1B Entrez, Source | calcium channel, voltage-dependent, L type, alpha 1B subunit | 2946 | 0.087 | -0.0168 | No |
| 22 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 2979 | 0.086 | -0.0150 | No |
| 23 | SLC2A4 | SLC2A4 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 4 | 3091 | 0.082 | -0.0193 | No |
| 24 | DLL1 | DLL1 Entrez, Source | delta-like 1 (Drosophila) | 3523 | 0.070 | -0.0483 | No |
| 25 | DUSP2 | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 3802 | 0.064 | -0.0661 | No |
| 26 | GPR20 | GPR20 Entrez, Source | G protein-coupled receptor 20 | 4025 | 0.059 | -0.0799 | No |
| 27 | ITGA7 | ITGA7 Entrez, Source | integrin, alpha 7 | 4309 | 0.053 | -0.0987 | No |
| 28 | JPH2 | JPH2 Entrez, Source | junctophilin 2 | 4479 | 0.049 | -0.1090 | No |
| 29 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 4870 | 0.040 | -0.1365 | No |
| 30 | KCNMB1 | KCNMB1 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, beta member 1 | 4885 | 0.040 | -0.1355 | No |
| 31 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 5084 | 0.036 | -0.1487 | No |
| 32 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 5315 | 0.032 | -0.1645 | No |
| 33 | FOXE3 | FOXE3 Entrez, Source | forkhead box E3 | 5412 | 0.030 | -0.1702 | No |
| 34 | PRKAB2 | PRKAB2 Entrez, Source | protein kinase, AMP-activated, beta 2 non-catalytic subunit | 5547 | 0.027 | -0.1790 | No |
| 35 | EGR3 | EGR3 Entrez, Source | early growth response 3 | 5611 | 0.025 | -0.1825 | No |
| 36 | PADI2 | PADI2 Entrez, Source | peptidyl arginine deiminase, type II | 5803 | 0.022 | -0.1958 | No |
| 37 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 6146 | 0.015 | -0.2209 | No |
| 38 | PLCB3 | PLCB3 Entrez, Source | phospholipase C, beta 3 (phosphatidylinositol-specific) | 6251 | 0.013 | -0.2281 | No |
| 39 | PLN | PLN Entrez, Source | phospholamban | 6355 | 0.011 | -0.2354 | No |
| 40 | FOXP1 | FOXP1 Entrez, Source | forkhead box P1 | 6378 | 0.010 | -0.2365 | No |
| 41 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 6493 | 0.008 | -0.2447 | No |
| 42 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 6869 | 0.001 | -0.2730 | No |
| 43 | NR4A1 | NR4A1 Entrez, Source | nuclear receptor subfamily 4, group A, member 1 | 6878 | 0.001 | -0.2736 | No |
| 44 | MRGPRF | MRGPRF Entrez, Source | MAS-related GPR, member F | 7140 | -0.005 | -0.2931 | No |
| 45 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 7183 | -0.006 | -0.2960 | No |
| 46 | TITF1 | TITF1 Entrez, Source | thyroid transcription factor 1 | 7264 | -0.008 | -0.3016 | No |
| 47 | DAPK3 | DAPK3 Entrez, Source | death-associated protein kinase 3 | 7689 | -0.016 | -0.3328 | No |
| 48 | MAP1A | MAP1A Entrez, Source | microtubule-associated protein 1A | 7727 | -0.017 | -0.3348 | No |
| 49 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 7740 | -0.017 | -0.3348 | No |
| 50 | PNKP | PNKP Entrez, Source | polynucleotide kinase 3'-phosphatase | 8307 | -0.030 | -0.3761 | No |
| 51 | FGFRL1 | FGFRL1 Entrez, Source | fibroblast growth factor receptor-like 1 | 8389 | -0.032 | -0.3806 | No |
| 52 | STAT5B | STAT5B Entrez, Source | signal transducer and activator of transcription 5B | 8858 | -0.043 | -0.4138 | No |
| 53 | RHOJ | RHOJ Entrez, Source | ras homolog gene family, member J | 8997 | -0.046 | -0.4219 | No |
| 54 | GGN | GGN Entrez, Source | gametogenetin | 9072 | -0.048 | -0.4251 | No |
| 55 | GFPT2 | GFPT2 Entrez, Source | glutamine-fructose-6-phosphate transaminase 2 | 9121 | -0.049 | -0.4263 | No |
| 56 | CRK | CRK Entrez, Source | v-crk sarcoma virus CT10 oncogene homolog (avian) | 9176 | -0.051 | -0.4279 | No |
| 57 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 9477 | -0.059 | -0.4476 | No |
| 58 | SLC7A1 | SLC7A1 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 9628 | -0.063 | -0.4557 | No |
| 59 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 9796 | -0.068 | -0.4649 | No |
| 60 | RASD2 | RASD2 Entrez, Source | RASD family, member 2 | 9887 | -0.071 | -0.4682 | No |
| 61 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 10001 | -0.075 | -0.4730 | No |
| 62 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 10034 | -0.076 | -0.4716 | No |
| 63 | CKM | CKM Entrez, Source | creatine kinase, muscle | 10056 | -0.076 | -0.4694 | No |
| 64 | ASB2 | ASB2 Entrez, Source | ankyrin repeat and SOCS box-containing 2 | 10090 | -0.078 | -0.4680 | No |
| 65 | MUS81 | MUS81 Entrez, Source | MUS81 endonuclease homolog (S. cerevisiae) | 10208 | -0.082 | -0.4727 | No |
| 66 | HOXA5 | HOXA5 Entrez, Source | homeobox A5 | 10345 | -0.086 | -0.4787 | No |
| 67 | GRK6 | GRK6 Entrez, Source | G protein-coupled receptor kinase 6 | 10414 | -0.089 | -0.4794 | No |
| 68 | SIPA1 | SIPA1 Entrez, Source | signal-induced proliferation-associated gene 1 | 10416 | -0.089 | -0.4750 | No |
| 69 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 10578 | -0.094 | -0.4825 | No |
| 70 | ACTB | ACTB Entrez, Source | actin, beta | 10590 | -0.095 | -0.4785 | No |
| 71 | MCAM | MCAM Entrez, Source | melanoma cell adhesion molecule | 10886 | -0.106 | -0.4955 | No |
| 72 | PDLIM4 | PDLIM4 Entrez, Source | PDZ and LIM domain 4 | 11133 | -0.119 | -0.5082 | No |
| 73 | PFN1 | PFN1 Entrez, Source | profilin 1 | 11162 | -0.120 | -0.5043 | No |
| 74 | FOSL1 | FOSL1 Entrez, Source | FOS-like antigen 1 | 11180 | -0.120 | -0.4996 | No |
| 75 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 11492 | -0.137 | -0.5162 | Yes |
| 76 | TPM3 | TPM3 Entrez, Source | tropomyosin 3 | 11497 | -0.137 | -0.5096 | Yes |
| 77 | ITGB6 | ITGB6 Entrez, Source | integrin, beta 6 | 11573 | -0.142 | -0.5082 | Yes |
| 78 | ACTR3 | ACTR3 Entrez, Source | ARP3 actin-related protein 3 homolog (yeast) | 11578 | -0.142 | -0.5014 | Yes |
| 79 | MATR3 | MATR3 Entrez, Source | matrin 3 | 11605 | -0.144 | -0.4962 | Yes |
| 80 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 11630 | -0.145 | -0.4907 | Yes |
| 81 | ACTG2 | ACTG2 Entrez, Source | actin, gamma 2, smooth muscle, enteric | 11806 | -0.157 | -0.4961 | Yes |
| 82 | YWHAZ | YWHAZ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 11826 | -0.159 | -0.4895 | Yes |
| 83 | DNAJB4 | DNAJB4 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 4 | 11966 | -0.170 | -0.4916 | Yes |
| 84 | ACVR1 | ACVR1 Entrez, Source | activin A receptor, type I | 11998 | -0.173 | -0.4852 | Yes |
| 85 | MYO1E | MYO1E Entrez, Source | myosin IE | 12127 | -0.184 | -0.4857 | Yes |
| 86 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 12156 | -0.187 | -0.4785 | Yes |
| 87 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 12248 | -0.199 | -0.4754 | Yes |
| 88 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 12275 | -0.202 | -0.4673 | Yes |
| 89 | LCP1 | LCP1 Entrez, Source | lymphocyte cytosolic protein 1 (L-plastin) | 12308 | -0.205 | -0.4594 | Yes |
| 90 | DIXDC1 | DIXDC1 Entrez, Source | DIX domain containing 1 | 12467 | -0.223 | -0.4602 | Yes |
| 91 | CFL1 | CFL1 Entrez, Source | cofilin 1 (non-muscle) | 12500 | -0.229 | -0.4512 | Yes |
| 92 | PHF12 | PHF12 Entrez, Source | PHD finger protein 12 | 12514 | -0.231 | -0.4406 | Yes |
| 93 | CAP1 | CAP1 Entrez, Source | CAP, adenylate cyclase-associated protein 1 (yeast) | 12522 | -0.231 | -0.4295 | Yes |
| 94 | TGFB1I1 | TGFB1I1 Entrez, Source | transforming growth factor beta 1 induced transcript 1 | 12535 | -0.233 | -0.4188 | Yes |
| 95 | POPDC2 | POPDC2 Entrez, Source | popeye domain containing 2 | 12600 | -0.245 | -0.4113 | Yes |
| 96 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 12692 | -0.262 | -0.4051 | Yes |
| 97 | SSH3 | SSH3 Entrez, Source | slingshot homolog 3 (Drosophila) | 12705 | -0.265 | -0.3927 | Yes |
| 98 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 12818 | -0.293 | -0.3865 | Yes |
| 99 | CNN1 | CNN1 Entrez, Source | calponin 1, basic, smooth muscle | 13134 | -0.456 | -0.3875 | Yes |
| 100 | PDLIM7 | PDLIM7 Entrez, Source | PDZ and LIM domain 7 (enigma) | 13170 | -0.508 | -0.3647 | Yes |
| 101 | TCF2 | TCF2 Entrez, Source | transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor | 13184 | -0.532 | -0.3390 | Yes |
| 102 | FHL2 | FHL2 Entrez, Source | four and a half LIM domains 2 | 13196 | -0.560 | -0.3118 | Yes |
| 103 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13226 | -0.619 | -0.2831 | Yes |
| 104 | PPP2R3A | PPP2R3A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha | 13267 | -0.745 | -0.2488 | Yes |
| 105 | LTBP1 | LTBP1 Entrez, Source | latent transforming growth factor beta binding protein 1 | 13278 | -0.786 | -0.2102 | Yes |
| 106 | TAGLN | TAGLN Entrez, Source | transgelin | 13326 | -1.131 | -0.1572 | Yes |
| 107 | CA3 | CA3 Entrez, Source | carbonic anhydrase III, muscle specific | 13339 | -1.580 | -0.0790 | Yes |
| 108 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.581 | 0.0002 | Yes |
