Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | V$SRF_Q5_01 |
| Enrichment Score (ES) | -0.47788927 |
| Normalized Enrichment Score (NES) | -1.7572246 |
| Nominal p-value | 0.0019120459 |
| FDR q-value | 0.06100189 |
| FWER p-Value | 0.986 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 101 | 0.614 | 0.0236 | No |
| 2 | PPAP2B | PPAP2B Entrez, Source | phosphatidic acid phosphatase type 2B | 205 | 0.467 | 0.0395 | No |
| 3 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 299 | 0.398 | 0.0527 | No |
| 4 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 383 | 0.346 | 0.0640 | No |
| 5 | SLC16A6 | SLC16A6 Entrez, Source | solute carrier family 16, member 6 (monocarboxylic acid transporter 7) | 394 | 0.340 | 0.0806 | No |
| 6 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 402 | 0.338 | 0.0972 | No |
| 7 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 470 | 0.312 | 0.1080 | No |
| 8 | IER2 | IER2 Entrez, Source | immediate early response 2 | 634 | 0.257 | 0.1088 | No |
| 9 | EGR1 | EGR1 Entrez, Source | early growth response 1 | 795 | 0.221 | 0.1079 | No |
| 10 | ASPA | ASPA Entrez, Source | aspartoacylase (Canavan disease) | 1027 | 0.189 | 0.1001 | No |
| 11 | KCNK3 | KCNK3 Entrez, Source | potassium channel, subfamily K, member 3 | 1094 | 0.183 | 0.1043 | No |
| 12 | MBNL1 | MBNL1 Entrez, Source | muscleblind-like (Drosophila) | 1343 | 0.161 | 0.0938 | No |
| 13 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 1414 | 0.156 | 0.0964 | No |
| 14 | CRH | CRH Entrez, Source | corticotropin releasing hormone | 1929 | 0.125 | 0.0639 | No |
| 15 | COL23A1 | COL23A1 Entrez, Source | collagen, type XXIII, alpha 1 | 2039 | 0.120 | 0.0618 | No |
| 16 | DGKG | DGKG Entrez, Source | diacylglycerol kinase, gamma 90kDa | 2425 | 0.106 | 0.0381 | No |
| 17 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 2527 | 0.102 | 0.0356 | No |
| 18 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 2538 | 0.101 | 0.0400 | No |
| 19 | IL17B | IL17B Entrez, Source | interleukin 17B | 2561 | 0.101 | 0.0435 | No |
| 20 | CACNA1B | CACNA1B Entrez, Source | calcium channel, voltage-dependent, L type, alpha 1B subunit | 2946 | 0.087 | 0.0188 | No |
| 21 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 2979 | 0.086 | 0.0208 | No |
| 22 | SLC2A4 | SLC2A4 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 4 | 3091 | 0.082 | 0.0165 | No |
| 23 | OTX1 | OTX1 Entrez, Source | orthodenticle homolog 1 (Drosophila) | 3094 | 0.082 | 0.0205 | No |
| 24 | TNMD | TNMD Entrez, Source | tenomodulin | 3422 | 0.073 | -0.0005 | No |
| 25 | DLL1 | DLL1 Entrez, Source | delta-like 1 (Drosophila) | 3523 | 0.070 | -0.0044 | No |
| 26 | FLNC | FLNC Entrez, Source | filamin C, gamma (actin binding protein 280) | 3577 | 0.069 | -0.0049 | No |
| 27 | NPPA | NPPA Entrez, Source | natriuretic peptide precursor A | 3581 | 0.069 | -0.0016 | No |
| 28 | TRDN | TRDN Entrez, Source | triadin | 3917 | 0.062 | -0.0238 | No |
| 29 | GPR20 | GPR20 Entrez, Source | G protein-coupled receptor 20 | 4025 | 0.059 | -0.0289 | No |
| 30 | FGF17 | FGF17 Entrez, Source | fibroblast growth factor 17 | 4439 | 0.050 | -0.0576 | No |
| 31 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 5251 | 0.033 | -0.1172 | No |
| 32 | RIMS1 | RIMS1 Entrez, Source | regulating synaptic membrane exocytosis 1 | 5299 | 0.032 | -0.1192 | No |
| 33 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 5315 | 0.032 | -0.1187 | No |
| 34 | FOXE3 | FOXE3 Entrez, Source | forkhead box E3 | 5412 | 0.030 | -0.1244 | No |
| 35 | PRKAB2 | PRKAB2 Entrez, Source | protein kinase, AMP-activated, beta 2 non-catalytic subunit | 5547 | 0.027 | -0.1332 | No |
| 36 | EGR3 | EGR3 Entrez, Source | early growth response 3 | 5611 | 0.025 | -0.1367 | No |
| 37 | NFATC4 | NFATC4 Entrez, Source | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 5709 | 0.024 | -0.1428 | No |
| 38 | PADI2 | PADI2 Entrez, Source | peptidyl arginine deiminase, type II | 5803 | 0.022 | -0.1487 | No |
| 39 | FGF7 | FGF7 Entrez, Source | fibroblast growth factor 7 (keratinocyte growth factor) | 5913 | 0.020 | -0.1559 | No |
| 40 | PLCB3 | PLCB3 Entrez, Source | phospholipase C, beta 3 (phosphatidylinositol-specific) | 6251 | 0.013 | -0.1807 | No |
| 41 | PLN | PLN Entrez, Source | phospholamban | 6355 | 0.011 | -0.1880 | No |
| 42 | FOXP1 | FOXP1 Entrez, Source | forkhead box P1 | 6378 | 0.010 | -0.1891 | No |
| 43 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 6493 | 0.008 | -0.1973 | No |
| 44 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 6561 | 0.007 | -0.2021 | No |
| 45 | MRGPRF | MRGPRF Entrez, Source | MAS-related GPR, member F | 7140 | -0.005 | -0.2455 | No |
| 46 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 7183 | -0.006 | -0.2484 | No |
| 47 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 7299 | -0.008 | -0.2566 | No |
| 48 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 7328 | -0.009 | -0.2583 | No |
| 49 | NRXN3 | NRXN3 Entrez, Source | neurexin 3 | 7351 | -0.009 | -0.2595 | No |
| 50 | KCNH2 | KCNH2 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 2 | 7491 | -0.012 | -0.2694 | No |
| 51 | TAF5L | TAF5L Entrez, Source | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa | 7524 | -0.013 | -0.2712 | No |
| 52 | MAP2K6 | MAP2K6 Entrez, Source | mitogen-activated protein kinase kinase 6 | 7666 | -0.016 | -0.2810 | No |
| 53 | MAP1A | MAP1A Entrez, Source | microtubule-associated protein 1A | 7727 | -0.017 | -0.2847 | No |
| 54 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 7740 | -0.017 | -0.2847 | No |
| 55 | SLC4A3 | SLC4A3 Entrez, Source | solute carrier family 4, anion exchanger, member 3 | 7978 | -0.023 | -0.3014 | No |
| 56 | FGF8 | FGF8 Entrez, Source | fibroblast growth factor 8 (androgen-induced) | 8216 | -0.028 | -0.3179 | No |
| 57 | FGFRL1 | FGFRL1 Entrez, Source | fibroblast growth factor receptor-like 1 | 8389 | -0.032 | -0.3293 | No |
| 58 | STAT5B | STAT5B Entrez, Source | signal transducer and activator of transcription 5B | 8858 | -0.043 | -0.3625 | No |
| 59 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 8907 | -0.044 | -0.3639 | No |
| 60 | RHOJ | RHOJ Entrez, Source | ras homolog gene family, member J | 8997 | -0.046 | -0.3683 | No |
| 61 | GGN | GGN Entrez, Source | gametogenetin | 9072 | -0.048 | -0.3715 | No |
| 62 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 9796 | -0.068 | -0.4226 | No |
| 63 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 10001 | -0.075 | -0.4343 | No |
| 64 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 10034 | -0.076 | -0.4328 | No |
| 65 | NPR3 | NPR3 Entrez, Source | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 10036 | -0.076 | -0.4291 | No |
| 66 | CKM | CKM Entrez, Source | creatine kinase, muscle | 10056 | -0.076 | -0.4266 | No |
| 67 | ASB2 | ASB2 Entrez, Source | ankyrin repeat and SOCS box-containing 2 | 10090 | -0.078 | -0.4252 | No |
| 68 | TRIM3 | TRIM3 Entrez, Source | tripartite motif-containing 3 | 10182 | -0.081 | -0.4279 | No |
| 69 | MUS81 | MUS81 Entrez, Source | MUS81 endonuclease homolog (S. cerevisiae) | 10208 | -0.082 | -0.4257 | No |
| 70 | GRK6 | GRK6 Entrez, Source | G protein-coupled receptor kinase 6 | 10414 | -0.089 | -0.4367 | No |
| 71 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 10578 | -0.094 | -0.4442 | No |
| 72 | ACTB | ACTB Entrez, Source | actin, beta | 10590 | -0.095 | -0.4402 | No |
| 73 | CSRP1 | CSRP1 Entrez, Source | cysteine and glycine-rich protein 1 | 10850 | -0.105 | -0.4545 | No |
| 74 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 11087 | -0.116 | -0.4664 | No |
| 75 | PFN1 | PFN1 Entrez, Source | profilin 1 | 11162 | -0.120 | -0.4659 | No |
| 76 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 11212 | -0.122 | -0.4634 | No |
| 77 | CDC25B | CDC25B Entrez, Source | cell division cycle 25B | 11352 | -0.129 | -0.4674 | No |
| 78 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 11492 | -0.137 | -0.4709 | Yes |
| 79 | TPM3 | TPM3 Entrez, Source | tropomyosin 3 | 11497 | -0.137 | -0.4643 | Yes |
| 80 | ITGB6 | ITGB6 Entrez, Source | integrin, beta 6 | 11573 | -0.142 | -0.4627 | Yes |
| 81 | ACTR3 | ACTR3 Entrez, Source | ARP3 actin-related protein 3 homolog (yeast) | 11578 | -0.142 | -0.4558 | Yes |
| 82 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 11630 | -0.145 | -0.4523 | Yes |
| 83 | ACTG2 | ACTG2 Entrez, Source | actin, gamma 2, smooth muscle, enteric | 11806 | -0.157 | -0.4575 | Yes |
| 84 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 11850 | -0.160 | -0.4526 | Yes |
| 85 | NRAS | NRAS Entrez, Source | neuroblastoma RAS viral (v-ras) oncogene homolog | 11999 | -0.173 | -0.4550 | Yes |
| 86 | MYO1E | MYO1E Entrez, Source | myosin IE | 12127 | -0.184 | -0.4553 | Yes |
| 87 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 12248 | -0.199 | -0.4543 | Yes |
| 88 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 12251 | -0.199 | -0.4443 | Yes |
| 89 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 12275 | -0.202 | -0.4358 | Yes |
| 90 | MYADM | MYADM Entrez, Source | myeloid-associated differentiation marker | 12280 | -0.202 | -0.4259 | Yes |
| 91 | LCP1 | LCP1 Entrez, Source | lymphocyte cytosolic protein 1 (L-plastin) | 12308 | -0.205 | -0.4175 | Yes |
| 92 | SDPR | SDPR Entrez, Source | serum deprivation response (phosphatidylserine binding protein) | 12367 | -0.211 | -0.4111 | Yes |
| 93 | MID1 | MID1 Entrez, Source | midline 1 (Opitz/BBB syndrome) | 12463 | -0.223 | -0.4070 | Yes |
| 94 | RERE | RERE Entrez, Source | arginine-glutamic acid dipeptide (RE) repeats | 12466 | -0.223 | -0.3958 | Yes |
| 95 | DIXDC1 | DIXDC1 Entrez, Source | DIX domain containing 1 | 12467 | -0.223 | -0.3845 | Yes |
| 96 | CFL1 | CFL1 Entrez, Source | cofilin 1 (non-muscle) | 12500 | -0.229 | -0.3753 | Yes |
| 97 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 12504 | -0.229 | -0.3639 | Yes |
| 98 | PHF12 | PHF12 Entrez, Source | PHD finger protein 12 | 12514 | -0.231 | -0.3528 | Yes |
| 99 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 12519 | -0.231 | -0.3414 | Yes |
| 100 | TGFB1I1 | TGFB1I1 Entrez, Source | transforming growth factor beta 1 induced transcript 1 | 12535 | -0.233 | -0.3307 | Yes |
| 101 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 12997 | -0.362 | -0.3471 | Yes |
| 102 | CNN1 | CNN1 Entrez, Source | calponin 1, basic, smooth muscle | 13134 | -0.456 | -0.3342 | Yes |
| 103 | PDLIM7 | PDLIM7 Entrez, Source | PDZ and LIM domain 7 (enigma) | 13170 | -0.508 | -0.3110 | Yes |
| 104 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13226 | -0.619 | -0.2837 | Yes |
| 105 | CXCL5 | CXCL5 Entrez, Source | chemokine (C-X-C motif) ligand 5 | 13257 | -0.714 | -0.2497 | Yes |
| 106 | PPP2R3A | PPP2R3A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha | 13267 | -0.745 | -0.2126 | Yes |
| 107 | TAGLN | TAGLN Entrez, Source | transgelin | 13326 | -1.131 | -0.1595 | Yes |
| 108 | CA3 | CA3 Entrez, Source | carbonic anhydrase III, muscle specific | 13339 | -1.580 | -0.0802 | Yes |
| 109 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.581 | 0.0002 | Yes |
