Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | V$USF_Q6_01 |
| Enrichment Score (ES) | -0.46947822 |
| Normalized Enrichment Score (NES) | -1.7224549 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.07129285 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ACACA | ACACA Entrez, Source | acetyl-Coenzyme A carboxylase alpha | 154 | 0.527 | 0.0257 | No |
| 2 | PDP2 | PDP2 Entrez, Source | - | 217 | 0.460 | 0.0536 | No |
| 3 | SC5DL | SC5DL Entrez, Source | sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like | 617 | 0.261 | 0.0419 | No |
| 4 | GNAS | GNAS Entrez, Source | GNAS complex locus | 968 | 0.198 | 0.0295 | No |
| 5 | STC2 | STC2 Entrez, Source | stanniocalcin 2 | 1024 | 0.190 | 0.0388 | No |
| 6 | MAX | MAX Entrez, Source | MYC associated factor X | 1464 | 0.152 | 0.0164 | No |
| 7 | SNIP | SNIP Entrez, Source | - | 1746 | 0.134 | 0.0047 | No |
| 8 | RAPGEF3 | RAPGEF3 Entrez, Source | Rap guanine nucleotide exchange factor (GEF) 3 | 2114 | 0.117 | -0.0147 | No |
| 9 | EGLN2 | EGLN2 Entrez, Source | egl nine homolog 2 (C. elegans) | 2499 | 0.103 | -0.0364 | No |
| 10 | WBP2 | WBP2 Entrez, Source | WW domain binding protein 2 | 2728 | 0.095 | -0.0470 | No |
| 11 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 2832 | 0.090 | -0.0483 | No |
| 12 | ATP7B | ATP7B Entrez, Source | ATPase, Cu++ transporting, beta polypeptide | 2900 | 0.088 | -0.0472 | No |
| 13 | SLC16A1 | SLC16A1 Entrez, Source | solute carrier family 16, member 1 (monocarboxylic acid transporter 1) | 2935 | 0.087 | -0.0436 | No |
| 14 | LTBR | LTBR Entrez, Source | lymphotoxin beta receptor (TNFR superfamily, member 3) | 3340 | 0.075 | -0.0688 | No |
| 15 | TAC1 | TAC1 Entrez, Source | tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma) | 3373 | 0.074 | -0.0659 | No |
| 16 | WDR23 | WDR23 Entrez, Source | WD repeat domain 23 | 3682 | 0.067 | -0.0845 | No |
| 17 | FGF5 | FGF5 Entrez, Source | fibroblast growth factor 5 | 3936 | 0.061 | -0.0992 | No |
| 18 | HTF9C | HTF9C Entrez, Source | - | 4181 | 0.055 | -0.1137 | No |
| 19 | CNOT4 | CNOT4 Entrez, Source | CCR4-NOT transcription complex, subunit 4 | 4218 | 0.055 | -0.1126 | No |
| 20 | SSR1 | SSR1 Entrez, Source | signal sequence receptor, alpha (translocon-associated protein alpha) | 4574 | 0.047 | -0.1361 | No |
| 21 | SYT13 | SYT13 Entrez, Source | synaptotagmin XIII | 4909 | 0.040 | -0.1585 | No |
| 22 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 5084 | 0.036 | -0.1691 | No |
| 23 | NFX1 | NFX1 Entrez, Source | nuclear transcription factor, X-box binding 1 | 5152 | 0.035 | -0.1716 | No |
| 24 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 5186 | 0.034 | -0.1717 | No |
| 25 | APLN | APLN Entrez, Source | apelin, AGTRL1 ligand | 5262 | 0.033 | -0.1751 | No |
| 26 | UBE2B | UBE2B Entrez, Source | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 5274 | 0.032 | -0.1736 | No |
| 27 | HOOK2 | HOOK2 Entrez, Source | hook homolog 2 (Drosophila) | 5283 | 0.032 | -0.1719 | No |
| 28 | SEPT3 | SEPT3 Entrez, Source | septin 3 | 5363 | 0.031 | -0.1757 | No |
| 29 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 5395 | 0.030 | -0.1759 | No |
| 30 | PPM1A | PPM1A Entrez, Source | protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform | 5471 | 0.029 | -0.1795 | No |
| 31 | HOXA1 | HOXA1 Entrez, Source | homeobox A1 | 5497 | 0.028 | -0.1795 | No |
| 32 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 5558 | 0.026 | -0.1821 | No |
| 33 | ATP6V1H | ATP6V1H Entrez, Source | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 5583 | 0.026 | -0.1821 | No |
| 34 | VGF | VGF Entrez, Source | VGF nerve growth factor inducible | 5814 | 0.022 | -0.1979 | No |
| 35 | RAB3IL1 | RAB3IL1 Entrez, Source | RAB3A interacting protein (rabin3)-like 1 | 5895 | 0.020 | -0.2025 | No |
| 36 | SLC26A2 | SLC26A2 Entrez, Source | solute carrier family 26 (sulfate transporter), member 2 | 5965 | 0.019 | -0.2064 | No |
| 37 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 6264 | 0.013 | -0.2280 | No |
| 38 | HRH3 | HRH3 Entrez, Source | histamine receptor H3 | 6371 | 0.010 | -0.2353 | No |
| 39 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 6556 | 0.007 | -0.2487 | No |
| 40 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 6686 | 0.004 | -0.2581 | No |
| 41 | RNF12 | RNF12 Entrez, Source | ring finger protein 12 | 6710 | 0.004 | -0.2596 | No |
| 42 | DNMT3A | DNMT3A Entrez, Source | DNA (cytosine-5-)-methyltransferase 3 alpha | 6724 | 0.004 | -0.2603 | No |
| 43 | PER1 | PER1 Entrez, Source | period homolog 1 (Drosophila) | 6849 | 0.001 | -0.2696 | No |
| 44 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 7004 | -0.002 | -0.2810 | No |
| 45 | VPS16 | VPS16 Entrez, Source | vacuolar protein sorting 16 (yeast) | 7143 | -0.005 | -0.2911 | No |
| 46 | SYT3 | SYT3 Entrez, Source | synaptotagmin III | 8168 | -0.027 | -0.3665 | No |
| 47 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 8204 | -0.028 | -0.3672 | No |
| 48 | WDR20 | WDR20 Entrez, Source | WD repeat domain 20 | 8249 | -0.029 | -0.3685 | No |
| 49 | NEUROD2 | NEUROD2 Entrez, Source | neurogenic differentiation 2 | 8448 | -0.033 | -0.3811 | No |
| 50 | TRIB1 | TRIB1 Entrez, Source | tribbles homolog 1 (Drosophila) | 8789 | -0.041 | -0.4039 | No |
| 51 | MYST3 | MYST3 Entrez, Source | MYST histone acetyltransferase (monocytic leukemia) 3 | 8920 | -0.044 | -0.4106 | No |
| 52 | GIT1 | GIT1 Entrez, Source | G protein-coupled receptor kinase interactor 1 | 9038 | -0.047 | -0.4161 | No |
| 53 | RPL19 | RPL19 Entrez, Source | ribosomal protein L19 | 9063 | -0.048 | -0.4146 | No |
| 54 | LZTS2 | LZTS2 Entrez, Source | leucine zipper, putative tumor suppressor 2 | 9078 | -0.048 | -0.4122 | No |
| 55 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 9082 | -0.048 | -0.4090 | No |
| 56 | FGF14 | FGF14 Entrez, Source | fibroblast growth factor 14 | 9294 | -0.054 | -0.4211 | No |
| 57 | RPS2 | RPS2 Entrez, Source | ribosomal protein S2 | 9340 | -0.055 | -0.4206 | No |
| 58 | ELK1 | ELK1 Entrez, Source | ELK1, member of ETS oncogene family | 9587 | -0.062 | -0.4348 | No |
| 59 | LAMP1 | LAMP1 Entrez, Source | lysosomal-associated membrane protein 1 | 9876 | -0.070 | -0.4515 | No |
| 60 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 10034 | -0.076 | -0.4580 | No |
| 61 | EIF3S9 | EIF3S9 Entrez, Source | eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa | 10066 | -0.077 | -0.4549 | No |
| 62 | AATF | AATF Entrez, Source | apoptosis antagonizing transcription factor | 10083 | -0.078 | -0.4507 | No |
| 63 | GNB2 | GNB2 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 10152 | -0.080 | -0.4501 | No |
| 64 | NR3C2 | NR3C2 Entrez, Source | nuclear receptor subfamily 3, group C, member 2 | 10284 | -0.084 | -0.4541 | No |
| 65 | APEX1 | APEX1 Entrez, Source | APEX nuclease (multifunctional DNA repair enzyme) 1 | 10323 | -0.086 | -0.4509 | No |
| 66 | GTF2A1 | GTF2A1 Entrez, Source | general transcription factor IIA, 1, 19/37kDa | 10365 | -0.087 | -0.4478 | No |
| 67 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 10369 | -0.087 | -0.4419 | No |
| 68 | EWSR1 | EWSR1 Entrez, Source | Ewing sarcoma breakpoint region 1 | 10512 | -0.092 | -0.4461 | No |
| 69 | BAX | BAX Entrez, Source | BCL2-associated X protein | 10699 | -0.098 | -0.4532 | No |
| 70 | HEXA | HEXA Entrez, Source | hexosaminidase A (alpha polypeptide) | 10771 | -0.102 | -0.4513 | No |
| 71 | RGL2 | RGL2 Entrez, Source | ral guanine nucleotide dissociation stimulator-like 2 | 10808 | -0.103 | -0.4468 | No |
| 72 | RNF44 | RNF44 Entrez, Source | ring finger protein 44 | 10881 | -0.106 | -0.4447 | No |
| 73 | COMMD3 | COMMD3 Entrez, Source | COMM domain containing 3 | 10982 | -0.111 | -0.4444 | No |
| 74 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 11315 | -0.127 | -0.4605 | Yes |
| 75 | HMOX1 | HMOX1 Entrez, Source | heme oxygenase (decycling) 1 | 11363 | -0.129 | -0.4549 | Yes |
| 76 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 11444 | -0.134 | -0.4514 | Yes |
| 77 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 11593 | -0.143 | -0.4524 | Yes |
| 78 | DUSP7 | DUSP7 Entrez, Source | dual specificity phosphatase 7 | 11765 | -0.153 | -0.4545 | Yes |
| 79 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 11816 | -0.158 | -0.4471 | Yes |
| 80 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 11850 | -0.160 | -0.4382 | Yes |
| 81 | ARL3 | ARL3 Entrez, Source | ADP-ribosylation factor-like 3 | 11949 | -0.169 | -0.4337 | Yes |
| 82 | NRAS | NRAS Entrez, Source | neuroblastoma RAS viral (v-ras) oncogene homolog | 11999 | -0.173 | -0.4251 | Yes |
| 83 | VLDLR | VLDLR Entrez, Source | very low density lipoprotein receptor | 12034 | -0.176 | -0.4152 | Yes |
| 84 | NEUROD1 | NEUROD1 Entrez, Source | neurogenic differentiation 1 | 12089 | -0.181 | -0.4065 | Yes |
| 85 | SLC31A2 | SLC31A2 Entrez, Source | solute carrier family 31 (copper transporters), member 2 | 12274 | -0.201 | -0.4061 | Yes |
| 86 | JUP | JUP Entrez, Source | junction plakoglobin | 12351 | -0.210 | -0.3970 | Yes |
| 87 | STX6 | STX6 Entrez, Source | syntaxin 6 | 12357 | -0.211 | -0.3824 | Yes |
| 88 | ADAM10 | ADAM10 Entrez, Source | ADAM metallopeptidase domain 10 | 12470 | -0.223 | -0.3751 | Yes |
| 89 | DCTN4 | DCTN4 Entrez, Source | dynactin 4 (p62) | 12513 | -0.230 | -0.3619 | Yes |
| 90 | WDR1 | WDR1 Entrez, Source | WD repeat domain 1 | 12568 | -0.238 | -0.3491 | Yes |
| 91 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 12695 | -0.263 | -0.3401 | Yes |
| 92 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12897 | -0.319 | -0.3326 | Yes |
| 93 | SCHIP1 | SCHIP1 Entrez, Source | schwannomin interacting protein 1 | 12910 | -0.326 | -0.3104 | Yes |
| 94 | SNN | SNN Entrez, Source | stannin | 12996 | -0.362 | -0.2912 | Yes |
| 95 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 12997 | -0.362 | -0.2655 | Yes |
| 96 | RHOQ | RHOQ Entrez, Source | ras homolog gene family, member Q | 13078 | -0.412 | -0.2424 | Yes |
| 97 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 13120 | -0.443 | -0.2141 | Yes |
| 98 | RAMP2 | RAMP2 Entrez, Source | receptor (calcitonin) activity modifying protein 2 | 13129 | -0.450 | -0.1828 | Yes |
| 99 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 13154 | -0.487 | -0.1502 | Yes |
| 100 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 13183 | -0.530 | -0.1147 | Yes |
| 101 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13288 | -0.823 | -0.0643 | Yes |
| 102 | BHLHB3 | BHLHB3 Entrez, Source | basic helix-loop-helix domain containing, class B, 3 | 13305 | -0.964 | 0.0028 | Yes |
