Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | WIELAND_HEPATITIS_B_INDUCED |
| Enrichment Score (ES) | -0.5230124 |
| Normalized Enrichment Score (NES) | -1.7157822 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.07384236 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HLA-DMA | HLA-DMA Entrez, Source | major histocompatibility complex, class II, DM alpha | 281 | 0.413 | 0.0198 | No |
| 2 | SOD2 | SOD2 Entrez, Source | superoxide dismutase 2, mitochondrial | 391 | 0.343 | 0.0455 | No |
| 3 | C3AR1 | C3AR1 Entrez, Source | complement component 3a receptor 1 | 1576 | 0.144 | -0.0293 | No |
| 4 | UBE2L6 | UBE2L6 Entrez, Source | ubiquitin-conjugating enzyme E2L 6 | 1789 | 0.132 | -0.0322 | No |
| 5 | CXCL9 | CXCL9 Entrez, Source | chemokine (C-X-C motif) ligand 9 | 1860 | 0.128 | -0.0248 | No |
| 6 | ISG20 | ISG20 Entrez, Source | interferon stimulated exonuclease gene 20kDa | 2032 | 0.120 | -0.0257 | No |
| 7 | FGL2 | FGL2 Entrez, Source | fibrinogen-like 2 | 2103 | 0.118 | -0.0193 | No |
| 8 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 2379 | 0.107 | -0.0294 | No |
| 9 | C1QB | C1QB Entrez, Source | complement component 1, q subcomponent, B chain | 2588 | 0.100 | -0.0351 | No |
| 10 | GZMA | GZMA Entrez, Source | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 2776 | 0.093 | -0.0400 | No |
| 11 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 2781 | 0.092 | -0.0312 | No |
| 12 | LAP3 | LAP3 Entrez, Source | leucine aminopeptidase 3 | 3371 | 0.074 | -0.0682 | No |
| 13 | IL10RA | IL10RA Entrez, Source | interleukin 10 receptor, alpha | 3536 | 0.070 | -0.0736 | No |
| 14 | LAPTM5 | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 3735 | 0.066 | -0.0820 | No |
| 15 | RAC2 | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 3759 | 0.065 | -0.0773 | No |
| 16 | SLC7A7 | SLC7A7 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 | 3774 | 0.065 | -0.0719 | No |
| 17 | HLA-DMB | HLA-DMB Entrez, Source | major histocompatibility complex, class II, DM beta | 3894 | 0.062 | -0.0747 | No |
| 18 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 4003 | 0.059 | -0.0770 | No |
| 19 | CD5L | CD5L Entrez, Source | CD5 molecule-like | 4458 | 0.049 | -0.1063 | No |
| 20 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 4819 | 0.041 | -0.1293 | No |
| 21 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 4898 | 0.040 | -0.1312 | No |
| 22 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 5128 | 0.035 | -0.1449 | No |
| 23 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 5204 | 0.034 | -0.1472 | No |
| 24 | LPXN | LPXN Entrez, Source | leupaxin | 5312 | 0.032 | -0.1521 | No |
| 25 | IGSF6 | IGSF6 Entrez, Source | immunoglobulin superfamily, member 6 | 5385 | 0.030 | -0.1545 | No |
| 26 | TYROBP | TYROBP Entrez, Source | TYRO protein tyrosine kinase binding protein | 5564 | 0.026 | -0.1653 | No |
| 27 | CTSC | CTSC Entrez, Source | cathepsin C | 6008 | 0.018 | -0.1968 | No |
| 28 | GZMK | GZMK Entrez, Source | granzyme K (granzyme 3; tryptase II) | 6017 | 0.018 | -0.1957 | No |
| 29 | EMR1 | EMR1 Entrez, Source | egf-like module containing, mucin-like, hormone receptor-like 1 | 6555 | 0.007 | -0.2354 | No |
| 30 | TAPBP | TAPBP Entrez, Source | TAP binding protein (tapasin) | 7131 | -0.005 | -0.2782 | No |
| 31 | PSMB10 | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 8574 | -0.036 | -0.3832 | No |
| 32 | B2M | B2M Entrez, Source | beta-2-microglobulin | 8650 | -0.038 | -0.3851 | No |
| 33 | CD3D | CD3D Entrez, Source | CD3d molecule, delta (CD3-TCR complex) | 9132 | -0.050 | -0.4164 | No |
| 34 | PSME2 | PSME2 Entrez, Source | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 9205 | -0.051 | -0.4167 | No |
| 35 | GIMAP5 | GIMAP5 Entrez, Source | GTPase, IMAP family member 5 | 9398 | -0.057 | -0.4255 | No |
| 36 | PPT1 | PPT1 Entrez, Source | palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) | 9878 | -0.071 | -0.4546 | No |
| 37 | CD48 | CD48 Entrez, Source | CD48 molecule | 9919 | -0.072 | -0.4504 | No |
| 38 | CD53 | CD53 Entrez, Source | CD53 molecule | 10105 | -0.078 | -0.4566 | No |
| 39 | WARS | WARS Entrez, Source | tryptophanyl-tRNA synthetase | 10462 | -0.090 | -0.4744 | No |
| 40 | PSME1 | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 10589 | -0.095 | -0.4745 | No |
| 41 | CD74 | CD74 Entrez, Source | CD74 molecule, major histocompatibility complex, class II invariant chain | 10944 | -0.109 | -0.4903 | No |
| 42 | SP110 | SP110 Entrez, Source | SP110 nuclear body protein | 11080 | -0.116 | -0.4891 | No |
| 43 | CTSB | CTSB Entrez, Source | cathepsin B | 11532 | -0.139 | -0.5092 | Yes |
| 44 | PTTG1 | PTTG1 Entrez, Source | pituitary tumor-transforming 1 | 11624 | -0.145 | -0.5017 | Yes |
| 45 | GM2A | GM2A Entrez, Source | GM2 ganglioside activator | 11694 | -0.149 | -0.4921 | Yes |
| 46 | PSMB9 | PSMB9 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 11832 | -0.159 | -0.4867 | Yes |
| 47 | TPP1 | TPP1 Entrez, Source | tripeptidyl peptidase I | 11989 | -0.172 | -0.4813 | Yes |
| 48 | TYMS | TYMS Entrez, Source | thymidylate synthetase | 12013 | -0.174 | -0.4658 | Yes |
| 49 | CD38 | CD38 Entrez, Source | CD38 molecule | 12249 | -0.199 | -0.4638 | Yes |
| 50 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 12432 | -0.219 | -0.4558 | Yes |
| 51 | CFL1 | CFL1 Entrez, Source | cofilin 1 (non-muscle) | 12500 | -0.229 | -0.4381 | Yes |
| 52 | AURKA | AURKA Entrez, Source | aurora kinase A | 12548 | -0.235 | -0.4184 | Yes |
| 53 | CD68 | CD68 Entrez, Source | CD68 molecule | 12654 | -0.254 | -0.4011 | Yes |
| 54 | CXCL11 | CXCL11 Entrez, Source | chemokine (C-X-C motif) ligand 11 | 12838 | -0.299 | -0.3852 | Yes |
| 55 | RAB27A | RAB27A Entrez, Source | RAB27A, member RAS oncogene family | 12981 | -0.351 | -0.3611 | Yes |
| 56 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 13154 | -0.487 | -0.3258 | Yes |
| 57 | GPNMB | GPNMB Entrez, Source | glycoprotein (transmembrane) nmb | 13207 | -0.576 | -0.2726 | Yes |
| 58 | UCP2 | UCP2 Entrez, Source | uncoupling protein 2 (mitochondrial, proton carrier) | 13284 | -0.808 | -0.1983 | Yes |
| 59 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13289 | -0.828 | -0.1164 | Yes |
| 60 | GBP2 | GBP2 Entrez, Source | guanylate binding protein 2, interferon-inducible | 13329 | -1.214 | 0.0010 | Yes |
