| Gene Set | Leading Edge Genes |
|---|
| NETPATH TGFBETA RECEPTOR PATHWAY UP | MAPK7, HBEGF, CLCF1, NFKBIA, EIF2C2, INHBA, RGS2, PDGFA, EDN1, MAPK6, TNFRSF12A, CYR61, SERPINE1, HIVEP2, ABCG1, IL1RAP, CTPS, RELA, FOSL1, AKAP12, TOM1, IER3, DUSP5, KLF10, SPRY2, TM4SF1, IL6, ATF3, PTGS2, PMP22, SLC7A5, SERPINB8, DDX21, TRIB3, MAP3K8, CHST11, PHLDA2, SLC7A11, TSPAN13, GFPT2, GTPBP2, EXT1, RELB, NEDD4, ENC1, ITGA2, PDK3, TOPORS, SERPINB9, FYN, RYBP, ACVR1, CRY1, ICAM1, TFPI2, RASAL2, MYC, RAI14, GADD45B, UAP1, ITGA6, SOX4, RP2, SLC7A1, PIM1, FHL2, KIAA0247, NRIP1, ATP1B1, ETS2, PLOD2, HMGCS1, TANK, MAPKAPK2, DAXX, PLAUR |
| SIGNAL TRANSDUCTION | MAPK7, RRAGC, EREG, HBEGF, DUSP6, HUS1, CLCF1, HOMER1, PMAIP1, OSMR, HIPK2, INHBA, CFLAR, RGS2, PDGFA, CXCL1, EDN1, PPARG, GSK3B, MAPK6, MOAP1, TNFSF9, TNFAIP3, MAP4K4, SOCS2, BNIP3, TTRAP, CCL20, EPHA2, DUSP10, CCL2, RELA, CASP7, SQSTM1, TRIP10, AKAP12, ALCAM, SPRED2, STAT1, REL, RGS12, KLF10, EIF2AK3, INPP1, RHEB, MALT1, TGFA, IL6, PSEN1, TICAM1, ATP2C1, OPN3, TRAF4, SIAH2, TP53BP2, GTPBP2, EXT1, RIPK2, CREM, GPRC5A, TRAF3, RIPK1, STK17A, RGS20, FYN, SERPINB9, GEM, ACVR1, CANT1, RASAL2, CD83, DUSP4, GADD45B, STAT4, TLE1, BIRC2, MAPRE2, DUSP8, VAPA, BIRC3, CXCL5, TANK, MAPKAPK2, DAXX, IL8, EPS8 |
| NETPATH IL 2 PATHWAY UP | DDX21, PFKFB3, ABCE1, SFPQ, NOLC1, BTG3, DUSP6, PMAIP1, RRAS2, FOS, CREM, CFLAR, NFKB1, IFIT1, MFHAS1, DENND3, FYN, SERPINE1, ICAM1, IRF1, MYC, SOCS2, SACS, DUSP4, LDLR, PDE4B, STAT4, CTPS, RELA, NR4A2, PIM1, TXNRD1, PPRC1, IER3, STAT1, KLF6, DUSP5, LIF, WARS, TOP1, TRIM21, ATP1B1, ETS2, IL6, MAPKAPK2, DAXX, IL8, SLC7A5, CHSY1, PLAUR |
| NEGATIVE REGULATION OF BIOLOGICAL PROCESS | RND1, EREG, TP53BP2, BTG3, ARID5B, CLCF1, OSGIN1, INHBA, CFLAR, NFKB1, TNIP1, CXCL1, FOSB, ZHX2, BTG1, GSK3B, IL1A, BCL2A1, TNFAIP8, SEMA4D, SERPINB9, RYBP, TNFAIP3, SERPINE1, ACVR1, SOCS2, MYC, ZBTB17, BNIP3, TLE1, CCL2, GADD45A, RELA, PLAGL1, PIM1, E2F6, IER3, BIRC3, ARHGEF2, LIF, KLF10, PPP1R15A, WARS, EIF2AK3, ANGPTL4, IL6, PSEN1, DAXX, IL8 |
| NETPATH IL 1 PATHWAY UP | NR4A3, CCL20, CCL2, PLK1, DUSP6, RELA, FOSL1, CXCL3, NFKBIA, AMPD3, UST, CXCL2, TXNRD1, SOD2, NFKB1, BIRC3, LIF, CXCL1, CXCL5, IL6, PTGS2, SERPINE1, IL8, MYC |
| RESPONSE TO EXTERNAL STIMULUS | ELF3, CCL20, IL1RAP, EREG, CCL2, RELA, FOSL1, RIPK2, FOS, CXCL2, ITGA2, NFKB1, CXCL1, THBD, PPARG, IL1A, TFPI, CXCL5, SERPINE1, IL8, PLAUR |
| NEGATIVE REGULATION OF CELLULAR PROCESS | RND1, EREG, TP53BP2, BTG3, ARID5B, CLCF1, OSGIN1, INHBA, CFLAR, NFKB1, CXCL1, FOSB, ZHX2, BTG1, GSK3B, IL1A, BCL2A1, TNFAIP8, SEMA4D, SERPINB9, RYBP, TNFAIP3, ACVR1, SOCS2, MYC, ZBTB17, TLE1, CCL2, GADD45A, RELA, PLAGL1, PIM1, E2F6, IER3, BIRC3, ARHGEF2, LIF, WARS, KLF10, PPP1R15A, EIF2AK3, ANGPTL4, IL6, PSEN1, DAXX, IL8 |
| NETPATH IL 5 PATHWAY UP | PLSCR1, PDE4B, SFPQ, CCL2, HBEGF, DUSP6, GADD45A, RELA, EGR1, CD55, PIM1, RELB, IER3, NFKB1, DUSP5, REL, PPIF, TRAF3, MAPK6, IL1A, RAB21, PMP22, ICAM1, IL8 |
| REACTOME SIGNALING IN IMMUNE SYSTEM | DUSP4, TRIB3, MAPK7, NFKB2, PPP2CB, ITGA6, MAP3K8, DUSP6, NRAS, MEF2A, RELA, MAP3K14, SLC7A11, NFKBIA, KRAS, RIPK2, FOS, NFKB1, RIPK1, THBD, MALT1, ATP1B1, FYN, PVRL2, MAPKAPK2, ICAM1, SLC7A5, TICAM1 |
| NETPATH IL 4 PATHWAY UP | CCL2, TP53BP2, ELL2, ARID5B, DUSP6, FJX1, RELA, MAP3K14, RIPK2, FOS, CREM, RGS2, NFKB1, GATA6, REL, SLC22A4, TFPI, EGLN3, IL6, MET, MYC |
| NEGATIVE REGULATION OF APOPTOSIS | CCL2, RELA, CLCF1, PIM1, IER3, CFLAR, NFKB1, BIRC3, IL1A, GSK3B, ANGPTL4, BCL2A1, SEMA4D, TNFAIP8, IL6, SERPINB9, ACVR1, PSEN1, SOCS2 |
| KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION | CCL20, CCL2, CLCF1, CXCL3, OSMR, INHBA, CXCL2, PDGFB, PDGFA, CXCL1, TNFRSF12A, IL1A, CXCL5, INHBC, TNFSF9, IL6, MET, ACVR1, IL8 |
| NEGATIVE REGULATION OF PROGRAMMED CELL DEATH | CCL2, RELA, CLCF1, PIM1, IER3, CFLAR, NFKB1, BIRC3, IL1A, GSK3B, ANGPTL4, BCL2A1, SEMA4D, TNFAIP8, IL6, SERPINB9, ACVR1, PSEN1, SOCS2 |
| RESPONSE TO WOUNDING | ELF3, CCL20, EREG, IL1RAP, RELA, RIPK2, FOS, CXCL2, ITGA2, NFKB1, CXCL1, THBD, TFPI, IL1A, SERPINE1, IL8 |
| PROTEIN KINASE CASCADE | ATP2C1, DUSP4, GADD45B, STAT4, DUSP10, CCL2, BIRC2, DUSP6, RELA, CLCF1, SQSTM1, HIPK2, DUSP8, RIPK2, SPRED2, VAPA, CFLAR, STAT1, REL, STK17A, MALT1, TGFA, FYN, TNFAIP3, MAPKAPK2, DAXX, CANT1, MAP4K4, TICAM1, SOCS2 |
| NETPATH TNF ALPHA PATHWAY DOWN | ABCG1, CCL20, IFIT5, MAP3K14, CXCL3, NFKBIA, EGR1, SDC4, CXCL2, IER3, NFKB1, KLF6, REL, CXCL1, KLF10, PPP1R15A, ZHX2, FOSB, MAPK6, GSK3B, DDX3X, TNFAIP2, MAFF, IL6, GEM, PTGS2, TNFAIP3, IRF1 |
| KEGG CHEMOKINE SIGNALING PATHWAY | NFKB1, STAT1, CCL20, CXCL1, CCL2, GSK3B, RELA, CXCL3, CXCL5, NFKBIA, IL8, CXCL2 |
| NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS | EREG, CCL2, RELA, CLCF1, TXNDC5, INHBA, PIM1, IER3, CFLAR, NFKB1, BIRC3, ANGPTL4, IL1A, GSK3B, BCL2A1, TNFAIP8, SEMA4D, IL6, SERPINB9, ACVR1, PSEN1, SOCS2, BNIP3 |
| IMMUNE SYSTEM PROCESS | CD83, CCL20, EREG, CCL2, MALT1, SEMA4D, IL6, FYN, GEM, TNFAIP1, INHBA, IL8 |
| NCI REG GR PATHWAY | SGK, NFKB1, STAT1, GSK3B, RELA, EGR1, IL6, IL8, IRF1, FOS |
| NETPATH IL 4 PATHWAY DOWN | PDGFB, CCL20, GADD45B, CCL2, NFKBIA, IL6, GEM, PTGS2, CXCL2, IRF1, IL8 |
| NETPATH KIT RECEPTOR PATHWAY UP | DUSP4, PPP2CB, CCL2, RELA, TFAP2C, IL6, EGR1, PIM1, FOS, MYC, TXNRD1, IER3 |
| KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY | NFKB1, CXCL1, CCL2, NFKBIA, IL6, TNFAIP3, RIPK2, CXCL2, IL8 |
| NCI IL23PATHWAY | NFKB1, NFKBIA, STAT1, IL6, CXCL1, STAT4, CCL2, RELA |
| EXTRACELLULAR SPACE | CCL20, CXCL1, EREG, CCL2, EDN1, FJX1, CXCL3, TNFAIP2, IL6, CXCL2, IL8 |
| NCI LYSOPHOSPHOLIPID PATHWAY | NFKB1, HBEGF, GSK3B, RELA, NFKBIA, IL6, PRKCD, IL8, FOS, GNAI1 |
| BEHAVIOR | CCL20, CXCL1, CCL2, FOSB, FOSL1, CXCL5, CXCL2, IL8, PLAUR |
| NETPATH B CELL RECEPTOR PATHWAY UP | RHOB, EPHA2, MAPK7, LDLR, EREG, CCL2, TP53BP2, NR4A2, EGR1, DUSP8, PIM1, FOS, CFLAR, BIRC3, ELF4, CSNK1A1, BCL2A1, RAB5A, TNFAIP3, BCAR3, SOCS2, MYC |
| IMMUNE RESPONSE | CD83, CCL20, EREG, CCL2, MALT1, IL6, FYN, GEM, TNFAIP1 |
| LOCOMOTORY BEHAVIOR | FOSL1, CXCL5, CCL20, CXCL1, CCL2, IL8, CXCL2, PLAUR |
| NETPATH EGFR1 PATHWAY UP | EMP1, NR4A3, DUSP4, EREG, PPP1R10, DUSP6, PHLDA2, GADD45A, EGR1, AKAP12, SDC4, ITGA2, IER3, GPRC5A, PHLDA1, LIF, SPRY2, EHD1, CXCL5, PTGS2, TNFAIP3, MET, TFPI2, MYC, PLAUR, DUSP1 |
| REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS | OPN3, CCL20, CXCL1, CCL2, EDN1, CXCL3, CXCL5, IL8, CXCL2 |
| REACTOME PEPTIDE LIGAND BINDING RECEPTORS | CCL20, CXCL1, CCL2, EDN1, CXCL3, CXCL5, IL8, CXCL2 |
| CYTOKINE ACTIVITY | CXCL3, CXCL5, CCL20, CXCL1, CCL2, IL8, CXCL2, SPRED2 |
| CHEMOKINE ACTIVITY | CXCL3, CXCL5, CCL20, CXCL1, CCL2, CXCL2, IL8 |
| DEFENSE RESPONSE | CD83, ELF3, CCL20, EREG, IL1RAP, RELA, FOSL1, VEZF1, INHBA, CXCL2, FOS, RIPK2, NFKB1, TNIP1, CXCL1, IL1A, IL8, BNIP3 |
| REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | CXCL3, CXCL5, CCL20, CXCL1, CCL2, CXCL2, IL8 |
| NCI NFAT TFPATHWAY | FOSL1, EGR1, PTGS2, CBLB, IL8, FOS, PPARG |
| NCI AMB2 NEUTROPHILS PATHWAY | NFKB1, IL6, CYR61, PLAUR |
| KEGG T CELL RECEPTOR SIGNALING PATHWAY | NFKB1, NFAT5, MAP3K8, MALT1, GSK3B, RELA, MAP3K14, NFKBIA, FYN, PPP3CC, CBLB, FOS |
| NCI IL2 1PATHWAY | STAT1, FYN, MAPKAPK2, FOS, SOCS2, MYC |
| REACTOME GPCR LIGAND BINDING | BDKRB1, OPN3, CCL20, CXCL1, EDN1, CCL2, FZD6, CXCL3, CXCL5, IL8, CXCL2 |
| KEGG TOLL LIKE RECEPTOR SIGNALING PATHWAY | NFKB1, NFKBIA, IL6, TRAF3, IL8, MAP3K8, TICAM1, RELA |
| RECEPTOR BINDING | JMJD1C, SDCBP, CCL20, EREG, CCL2, HBEGF, CLCF1, CXCL3, SQSTM1, OSGIN1, INHBA, CXCL2, CSF2, ALCAM, SPRED2, CXCL1, EDN1, TGFA, CXCL5, SEMA4D, EFNA1, INHBC, DAXX, IL8, PLXNC1, SOCS2 |
| KEGG JAK STAT SIGNALING PATHWAY | STAT1, LIF, STAT4, SPRY2, CLCF1, OSMR, IL6, CBLB, PIM1, SOCS2, MYC, SPRY1, SPRED2 |
| REACTOME TOLL LIKE RECEPTOR 3 CASCADE | NFKB1, DUSP4, MAPK7, NFKB2, PPP2CB, RIPK1, DUSP6, MEF2A, RELA, NFKBIA, MAPKAPK2, FOS, TICAM1 |
| CHEMOKINE RECEPTOR BINDING | CXCL3, CXCL5, CCL20, CXCL1, CCL2, CXCL2, IL8 |
| KEGG EPITHELIAL CELL SIGNALING IN HELICOBACTER PYLORI INFECTION | NFKB1, CXCL1, HBEGF, RELA, TJP1, MAP3K14, NFKBIA, MET, IL8 |
| NETPATH IL 3 PATHWAY UP | CCL2, PIM1, IL8, SOCS2, MYC |
| KEGG LEISHMANIA INFECTION | NFKB1, STAT1, NFKBIA, PTGS2, FOS, IL1A, RELA |
| NETPATH IL 6 PATHWAY UP | GADD45B, CXCL1, LDLR, PPARG, MAFF, PIM1, FOS, IRF1, SOCS2 |
| G PROTEIN COUPLED RECEPTOR BINDING | CXCL3, CXCL5, CCL20, CXCL1, CCL2, CXCL2, IL8 |
| INFLAMMATORY RESPONSE | NFKB1, ELF3, CCL20, CXCL1, IL1RAP, IL1A, RELA, IL8, RIPK2, CXCL2, FOS |
| BIOCARTA STEM PATHWAY | IL6, IL8 |
| NETPATH IL 9 PATHWAY UP | CCL2, PIM1, MYC, SOCS2 |
| NCI TNFPATHWAY | NFKB1, STAT1, BIRC3, RIPK1, MAP3K7IP2, BIRC2, RELA, SQSTM1, TNFAIP3, MAP4K4 |
| BIOCARTA IL1R PATHWAY | MAP3K14, NFKB1, NFKBIA, IL6, IL1A, RELA |
| NCI DISSOLUTION OF FIBRIN CLOT | SERPINE1, PLAUR |
| VIRAL REPRODUCTION | TNIP1, CCL2, IL8 |
| BIOCARTA IL17 PATHWAY | IL6, IL8 |
| REACTOME G ALPHA I SIGNALLING EVENTS | BDKRB1, OPN3, CCL20, CXCL1, CXCL3, CXCL5, CXCL2, IL8, GNAI1 |
| NCI IL12 2PATHWAY | NFKB1, STAT1, GADD45B, STAT4, RELA, RIPK2, FOS, RELB |
| VIRAL INFECTIOUS CYCLE | TNIP1, CCL2, IL8 |
| KEGG MAPK SIGNALING PATHWAY | DUSP4, GADD45B, MAPK7, DUSP10, MAP3K8, DUSP6, GADD45A, RELA, MAP3K14, DUSP14, PPP3CC, RRAS2, DUSP8, RELB, FOS, PDGFB, NFKB1, DUSP5, PDGFA, IL1A, MAPKAPK2, DAXX, MYC, DUSP1 |
| VIRAL GENOME REPLICATION | TNIP1, CCL2, IL8 |
| BIOCARTA CYTOKINE PATHWAY | IL6, IL8, IL1A |
| BIOCARTA NTHI PATHWAY | MAP3K14, NFKB1, NFKBIA, IL8, DUSP1, RELA |
| JAK STAT CASCADE | STAT1, STAT4, CCL2, SOCS2, CLCF1 |
| REACTOME TRAF6 MEDIATED INDUCTION OF THE ANTIVIRAL CYTOKINE IFN ALPHA BETA CASCADE | NFKB1, DUSP4, MAPK7, PPP2CB, DUSP6, MEF2A, RELA, NFKBIA, FOS, TICAM1 |
| KEGG RIG I LIKE RECEPTOR SIGNALING PATHWAY | NFKB1, TRAF3, DDX3Y, RELA, DDX3X, NFKBIA, TANK, IL8, DDX58 |
| REGULATION OF RESPONSE TO STIMULUS | FYN, EREG, IL8, MALT1 |
| BIOCARTA INFLAM PATHWAY | IL6, PDGFA, IL8, CSF2, IL1A |
| BIOCARTA GRANULOCYTES PATHWAY | ICAM1, IL8, IL1A |
| BIOCARTA NFKB PATHWAY | MAP3K14, NFKB1, NFKBIA, TNFAIP3, RIPK1, IL1A, RELA |
| POSITIVE REGULATION OF CELLULAR PROTEIN METABOLIC PROCESS | IL6, EREG, CDC42EP2, SAMD4A, CLCF1 |
| NETPATH IL 7 PATHWAY UP | CXCL3, CXCL5, CXCL1, TRAF3, IL8, CXCL2, MYC |
| ST ERK1 ERK2 MAPK PATHWAY | NFKB1, DUSP4, TRAF3, MAP3K8, DUSP6 |
| BIOCARTA CD40 PATHWAY | MAP3K14, NFKB1, NFKBIA, TNFAIP3, TRAF3, DUSP1, RELA |
| BIOCARTA ERYTH PATHWAY | IL6, CSF2, IL1A |
| NCI CHEMOKINE RECEPTORS BIND CHEMOKINES | CCL20 |
| REGULATION OF IMMUNE SYSTEM PROCESS | FYN, EREG, INHBA, MALT1 |
| NETPATH HEDGEHOG PATHWAY UP | PMP22, THBD, MYC |
| POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS | FYN, EREG, MALT1 |
| BIOCARTA CARDIACEGF PATHWAY | NFKB1, EDN1, FOS, MYC, RELA |
| PEPTIDYL TYROSINE MODIFICATION | STAT1, IL12A, LYN, CLCF1 |
| NCI TCRCALCIUMPATHWAY | FOSL1, PTGS2 |
| NCI ATF2 PATHWAY | IL6, ATF3, DUSP5, DUSP10, FOS, DUSP8, DUSP1 |
| NETPATH EGFR1 PATHWAY DOWN | IFIT1, EREG, BTG1, PPARG, ARID5B, SQSTM1, CLDN1, IER3 |
| BIOCARTA CCR5 PATHWAY | CCL2, FOS |
| BIOCARTA CDMAC PATHWAY | NFKB1, NFKBIA, FOS, MYC, RELA |
| REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | MAP3K14, FYN, TRIB3, MAP3K8 |
| CORUM CHUK-NFKB2-REL-IKBKG-SPAG9-NFKB1-NFKBIE-COPB2-TNIP1-NFKBIA-RELA-TNIP2 COMPLEX | NFKB1, NFKBIA, SPAG9, REL, TNIP1, RELA |
| POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS | FYN, EREG, MALT1 |
| PEPTIDYL TYROSINE PHOSPHORYLATION | STAT1, IL12A, LYN, CLCF1 |
| POSITIVE REGULATION OF IMMUNE RESPONSE | FYN, EREG, MALT1 |
| NCI CD40 PATHWAY | NFKB1, TTRAP, BIRC3, TRAF3, BIRC2, RELA, MAP3K14, NFKBIA, TNFAIP3, CBLB, MYC |
| POSITIVE REGULATION OF TRANSLATION | IL6, EREG, SAMD4A |
| REGULATION OF IMMUNE RESPONSE | FYN, EREG, MALT1 |
| POSITIVE REGULATION OF CELL PROLIFERATION | PDGFA, LIF, EREG, EDN1, TBC1D8, FOSL1, TGFA, CXCL5, IL6, MYC |
| BIOCARTA KERATINOCYTE PATHWAY | MAP3K14, ETS2, NFKB1, NFKBIA, PRKCH, DAXX, FOS, RELA |
| BIOCARTA TNFR2 PATHWAY | NFKB1, TRAF3, RELA, MAP3K14, NFKBIA, TNFAIP3, TANK, DUSP1 |
| NCI NFKAPPABCANONICALPATHWAY | NFKB1, CYLD, BIRC2, MALT1, RELA, NFKBIA, TNFAIP3, RIPK2, TRAF6 |
| POSITIVE REGULATION OF BIOLOGICAL PROCESS | |
| LEUKOCYTE ACTIVATION | |
| NETPATH IL 1 PATHWAY | |
| EXTRACELLULAR REGION PART | |
| REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | |
| NCI FGF PATHWAY | |
| KEGG HYPERTROPHIC CARDIOMYOPATHY HCM | |
| NETPATH T CELL RECEPTOR PATHWAY DOWN | |
| NCI IL2 STAT5PATHWAY | |
| BIOCARTA NKT PATHWAY | IL12A, CSF2 |
| I KAPPAB KINASE NF KAPPAB CASCADE | |
| BIOCARTA LAIR PATHWAY | |
| NCI IL2 PI3KPATHWAY | |
| KEGG FOCAL ADHESION | |
| REGULATION OF I KAPPAB KINASE NF KAPPAB CASCADE | |
| REGULATION OF PROTEIN KINASE ACTIVITY | GADD45B, TRIB3, EREG, MALT1, DUSP6, GADD45A, TRIB1, TGFA, DAXX, DUSP8, SPRED2 |
| NCI HIF1 TFPATHWAY | |
| CORUM AKAP250-PKA-PDE4D COMPLEX | |
| BIOCARTA LYM PATHWAY | |
| POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS | |
| ST GRANULE CELL SURVIVAL PATHWAY | |
| POSITIVE REGULATION OF METABOLIC PROCESS | |
| POSITIVE REGULATION OF RESPONSE TO STIMULUS | |
| ADAPTIVE IMMUNE RESPONSE GO 0002460 | MALT1 |
| BIOCARTA ETS PATHWAY | |
| REGULATION OF TRANSFERASE ACTIVITY | GADD45B, TRIB3, EREG, MALT1, DUSP6, GADD45A, TRIB1, TGFA, DAXX, DUSP8, SPRED2 |
| BIOCARTA WNT PATHWAY | |
| BIOCARTA RANKL PATHWAY | |
| CELL CELL SIGNALING | |
| T CELL DIFFERENTIATION | |
| NETPATH TNF ALPHA PATHWAY | |
| REACTOME MAP KINASES ACTIVATION IN TLR CASCADE | |
| REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION | CLCF1 |
| INNATE IMMUNE RESPONSE | |
| CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX CHUK KPNA3 NFKB2 NFKBIB REL IKBKG NFKB1 NFKBIE RELB NFKBIA RELA TNIP2 | |
| POSITIVE REGULATION OF ANGIOGENESIS | BTG1, ANGPTL4 |
| CALCIUM MEDIATED SIGNALING | |
| BIOCARTA HIVNEF PATHWAY | |
| NCI P38ALPHABETAPATHWAY | |
| NCI CD8TCRDOWNSTREAMPATHWAY | FOSL1, EGR1, STAT4, FOS |
| NETPATH TGFBETA RECEPTOR PATHWAY DOWN | |
| POSITIVE REGULATION OF CELL MIGRATION | |
| BIOCARTA 41BB PATHWAY | |
| NEGATIVE REGULATION OF TRANSFERASE ACTIVITY | |
| NCI P53DOWNSTREAMPATHWAY | |
| CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX RPL6 RPL30 RPS13 CHUK DDX3X NFKB2 NFKBIB REL IKBKG NFKB1 MAP3K8 RELB GLG1 NFKBIA RELA TNIP2 GTF2I | |
| REACTOME CD28 CO STIMULATION | |
| NETPATH IL 2 PATHWAY | |
| ST TUMOR NECROSIS FACTOR PATHWAY | |
| NCI HIF2PATHWAY | |
| ANATOMICAL STRUCTURE DEVELOPMENT | |
| POSITIVE REGULATION OF SIGNAL TRANSDUCTION | |
| NEGATIVE REGULATION OF MAP KINASE ACTIVITY | DUSP8, DUSP6, SPRED2 |
| CORUM NFKB1-NFKB2-REL-RELA-RELB COMPLEX | |
| POSITIVE REGULATION OF CELLULAR PROCESS | |
| POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS | |
| REGULATION OF CATALYTIC ACTIVITY | |
| VIRAL REPRODUCTIVE PROCESS | |
| POSITIVE REGULATION OF CELL DIFFERENTIATION | |
| INACTIVATION OF MAPK ACTIVITY | DUSP8, DUSP6, SPRED2 |
| NCI EPHRINBREVPATHWAY | |
| REGULATION OF KINASE ACTIVITY | GADD45B, TRIB3, EREG, MALT1, DUSP6, GADD45A, TRIB1, TGFA, DAXX, DUSP8, SPRED2 |
| NCI NFKAPPABATYPICALPATHWAY | |
| REACTOME DOWNSTREAM EVENTS IN GPCR SIGNALING | |
| BIOCARTA TALL1 PATHWAY | |
| NETPATH IL 7 PATHWAY | |
| ADAPTIVE IMMUNE RESPONSE | MALT1 |
| ANTI APOPTOSIS | |
| KEGG SMALL CELL LUNG CANCER | |
| POSITIVE REGULATION OF PHOSPHORYLATION | |
| REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | |
| NCI REGULATED PROTEOLYSIS OF P75NTR | |
| BIOCARTA PPARA PATHWAY | |
| REGULATION OF CYTOKINE PRODUCTION | |
| MAPKKK CASCADE GO 0000165 | |
| ORGAN DEVELOPMENT | |
| POSITIVE REGULATION OF CELLULAR METABOLIC PROCESS | |
| INTRACELLULAR SIGNALING CASCADE | |
| SIG CD40PATHWAYMAP | |
| REGULATION OF CELL ADHESION | |
| BIOCARTA RNA PATHWAY | |
| ST FAS SIGNALING PATHWAY | |
| CELL SURFACE RECEPTOR LINKED SIGNAL TRANSDUCTION GO 0007166 | |
| BIOCARTA DEATH PATHWAY | |
| REACTOME DOWNSTREAM TCR SIGNALING | |
| BIOCARTA STRESS PATHWAY | |
| REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT | |
| KEGG GAP JUNCTION | PDGFB, PDGFA, MAPK7, TUBB2B, NRAS, TJP1, KRAS, TUBB2A, TUBB6, ADCY3, GNAI1 |
| PROTEIN KINASE ACTIVITY | |
| REGULATION OF MULTICELLULAR ORGANISMAL PROCESS | |
| REACTOME TOLL RECEPTOR CASCADES | |
| KEGG HEMATOPOIETIC CELL LINEAGE | |
| REACTOME P75NTR SIGNALS VIA NFKB | |
| NCI CD28 DEPENDENT PI3K AKT SIGNALING | |
| NCI IL12 STAT4PATHWAY | |
| ORGAN MORPHOGENESIS | |
| BIOCARTA TOLL PATHWAY | |
| REACTOME MAPK KNOWN DRUG TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES | |
| REGULATION OF MAP KINASE ACTIVITY | |
| KEGG PATHWAYS IN CANCER | |
| NETPATH WNT PATHWAY UP | |
| BIOCARTA ARENRF2 PATHWAY | MAFF, FOS |