| Gene Set | Leading Edge Genes |
|---|
| NETPATH EGFR1 PATHWAY UP | EMP1, DUSP4, EREG, HBEGF, DUSP6, PHLDA2, CCND1, IL4R, DKK3, AKAP12, SDC4, UBE2N, TGM2, IER3, GPRC5A, PHLDA1, NP, SPRY2, TGFA, EHD1, PTGS2, TNFAIP3, MET, TFPI2, DUSP1, PLAUR |
| KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION | CXCL1, CCL2, IL18R1, TNFRSF12A, CRLF2, CLCF1, IL4R, CXCL3, CXCL5, TNFSF9, MET, ACVR1, TNFRSF9, IL8, CXCL2 |
| KEGG HEMATOPOIETIC CELL LINEAGE | IL4R, CD38, ANPEP, IL6R, CD9, ITGA6, CD59, CD55 |
| KEGG EPITHELIAL CELL SIGNALING IN HELICOBACTER PYLORI INFECTION | NFKB1, CXCL1, HBEGF, RELA, MAP3K14, SRC, NFKBIA, MET, IL8 |
| NCI NFAT TFPATHWAY | PTPN1, FOSL1, PTGS2, IL8 |
| LOCOMOTORY BEHAVIOR | FOSL1, CXCL1, CCL2, IL8, PLAUR |
| NCI DISSOLUTION OF FIBRIN CLOT | SERPINE1, PLAT, PLAUR |
| NCI LYSOPHOSPHOLIPID PATHWAY | NFKB1, HBEGF, GSK3B, GNA13, RELA, SRC, NFKBIA, GNA12, IL8 |
| KEGG RIG I LIKE RECEPTOR SIGNALING PATHWAY | NFKB1, DDX3X, TRIM25, NFKBIA, NFKBIB, ISG15, IL8, RELA |
| CHEMOKINE ACTIVITY | CXCL3, CXCL1, CCL2, IL8 |
| KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY | NFKBIA, NFKBIB, TNFAIP3, CXCL1, CCL2, IL8, CXCL2 |
| CHEMOKINE RECEPTOR BINDING | CXCL3, CXCL1, CCL2, IL8 |
| REACTOME TRAF6 MEDIATED INDUCTION OF THE ANTIVIRAL CYTOKINE IFN ALPHA BETA CASCADE | NFKB1, DUSP4, NFKBIB, NFKB2, DUSP6, NFKBIA, MAPKAPK2, TICAM1 |
| REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | CXCL3, CXCL1, CCL2, IL8 |
| BIOCARTA STEM PATHWAY | IL8 |
| NETPATH IL 1 PATHWAY | NFKB1, MAP3K14, NFKBIA, NFKBIB, MAP3K7IP2, RELA |
| KEGG ECM RECEPTOR INTERACTION | COL6A1, ITGAV, LAMB3, SDC4, ITGA6, TNC |
| KEGG MAPK SIGNALING PATHWAY | DUSP4, DUSP5, DUSP10, NFKB2, DUSP6, RELA, NRAS, MAP3K14, DUSP14, PPP3CC, DAXX, MAPKAPK2, MAP4K4, RELB, DUSP1 |
| BIOCARTA INFLAM PATHWAY | IL8 |
| NETPATH IL 7 PATHWAY UP | CXCL3, CXCL5, CXCL1, IL8, CXCL2 |
| KEGG T CELL RECEPTOR SIGNALING PATHWAY | NFKBIB, NCK2, MALT1, GSK3B, NRAS, RELA, MAP3K14, NFKBIA, PPP3CC, CBLB |
| BIOCARTA IL17 PATHWAY | CD58, IL8 |
| POSITIVE REGULATION OF CELL PROLIFERATION | TGFA, FOSL1, SPHK1, EREG, CDK2 |
| CORUM CHUK-NFKB2-REL-IKBKG-SPAG9-NFKB1-NFKBIE-COPB2-TNIP1-NFKBIA-RELA-TNIP2 COMPLEX | NFKB1, NFKBIA, SPAG9, REL, TNIP1, NFKB2, TNIP2, RELA |
| KEGG CYTOSOLIC DNA SENSING PATHWAY | NFKB1, NFKBIA, NFKBIB, DDX58, RELA |
| BIOCARTA CYTOKINE PATHWAY | IL8 |
| POSITIVE REGULATION OF CYTOKINE PRODUCTION | EREG, MALT1 |
| BIOCARTA ERYTH PATHWAY | |
| POSITIVE REGULATION OF IMMUNE RESPONSE | EREG, MALT1 |
| CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX CHUK KPNA3 NFKB2 NFKBIB REL IKBKG NFKB1 NFKBIE RELB NFKBIA RELA TNIP2 | |
| NCI CD40 PATHWAY | MAP3K14, NFKBIA, BIRC3, TNFAIP3, BIRC2, RELA |
| KEGG HYPERTROPHIC CARDIOMYOPATHY HCM | ITGAV, ITGA6, PRKAG2 |
| REGULATION OF IMMUNE RESPONSE | EREG, MALT1 |
| BIOCARTA CDMAC PATHWAY | NFKBIA, RELA |
| BIOCARTA ASBCELL PATHWAY | |
| CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX RPL6 RPL30 RPS13 CHUK DDX3X NFKB2 NFKBIB REL IKBKG NFKB1 MAP3K8 RELB GLG1 NFKBIA RELA TNIP2 GTF2I | |
| BIOCARTA TNFR2 PATHWAY | MAP3K14, NFKBIA, TNFAIP3, DUSP1, RELA |
| ST TUMOR NECROSIS FACTOR PATHWAY | |
| POSITIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION | CLCF1 |
| POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS | SPHK1, EREG, MALT1 |
| BIOCARTA DC PATHWAY | |
| POSITIVE REGULATION OF RESPONSE TO STIMULUS | |