| Gene Set | Leading Edge Genes |
|---|
| NETPATH EGFR1 PATHWAY UP | EMP1, EREG, ITGA3, HPCAL1, CCND1, PLAU, TCOF1, SOX9, AKAP12, SDC4, COTL1, TGM2, IER3, GPRC5A, NP, TGFA, TNFAIP3, MET, TFPI2, PLAUR |
| LOCOMOTORY BEHAVIOR | FOSL1, PLAU, CXCL1, CCL2, IL8, PLAUR, FGF2 |
| NCI DISSOLUTION OF FIBRIN CLOT | PLAU, SERPINE1, PLAT, PLAUR |
| KEGG CHEMOKINE SIGNALING PATHWAY | CXCL1, PIK3R1, CCL2, RELA, CXCL5, NFKBIA, ADCY7, IL8, GRK5, CXCL2, PXN |
| KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION | CCL2, VEGFC, OSMR, IL22RA1, BMPR2, CXCL2, IL17RA, PDGFA, CXCL1, VEGFB, LIFR, TNFRSF11A, CXCL5, FAS, MET, IL8 |
| KEGG APOPTOSIS | BIRC3, PIK3R3, IRAK1, PIK3R1, TRAF2, BIRC2, CAPN1, CASP7, RELA, MAP3K14, NFKBIA, FAS, ENDOD1, BID, CFLAR, MYD88 |
| NCI NFAT TFPATHWAY | FOSL1, CALM1, JUNB, IL8 |
| CHEMOKINE ACTIVITY | CXCL1, CCL2, IL8 |
| VIRAL GENOME REPLICATION | TNIP1, CCL2, IL8 |
| KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY | BIRC3, CXCL1, CCL2, BIRC2, RELA, NFKBIA, TNFAIP3, IL8, CXCL2 |
| CHEMOKINE RECEPTOR BINDING | CXCL1, CCL2, IL8 |
| REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | CXCL1, CCL2, IL8 |
| KEGG RIG I LIKE RECEPTOR SIGNALING PATHWAY | ISG15, TRAF3, TRAF2, DDX3Y, IKBKE, RELA, DDX3X, TRIM25, NFKBIA, IL8, DDX58 |
| BIOCARTA STEM PATHWAY | IL8 |
| LEUKOCYTE CHEMOTAXIS | IL8 |
| REGULATION OF RESPONSE TO STIMULUS | EREG, TRAF2, IL8 |
| NETPATH IL 7 PATHWAY UP | CXCL5, CXCL1, MCL1, TRAF3, IL8, CXCL2 |
| BIOCARTA INFLAM PATHWAY | PDGFA, IL8 |
| CELL MIGRATION | VEGFC, PPAP2B, SPHK1, IL8 |
| POSITIVE REGULATION OF CELL PROLIFERATION | SPHK1, PDGFA, EREG, VEGFB, CD47, CAPN1, RHOG, TGFA, FOSL1, TBX3, TBRG4 |
| BIOCARTA CYTOKINE PATHWAY | IL8 |
| BIOCARTA LYM PATHWAY | IL8 |
| POSITIVE REGULATION OF RESPONSE TO STIMULUS | EREG, TRAF2, IL8 |
| POSITIVE REGULATION OF DEFENSE RESPONSE | EREG |
| BIOCARTA NFKB PATHWAY | MAP3K14, NFKBIA, IRAK1, TNFAIP3, MYD88, RELA |
| REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION | |
| NCI TNFPATHWAY | SQSTM1, BIRC3, TNFAIP3, MAP4K4, TRAF2, BIRC2, RELA |
| NCI CD40 PATHWAY | MAP3K14, NFKBIA, BIRC3, TNFAIP3, TRAF2, TRAF3, BIRC2, RELA |
| CELLULAR DEFENSE RESPONSE | FOSL1, MICB |
| KEGG CYTOSOLIC DNA SENSING PATHWAY | POLR1C, NFKBIA, IRF3, PYCARD, IKBKE, DDX58, RELA |
| POSITIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION | |
| ST TUMOR NECROSIS FACTOR PATHWAY | NFKBIA, BIRC3, TNFAIP3, NFKBIE, TRAF2, BIRC2, CFLAR |
| REGULATION OF JAK STAT CASCADE | HGS |