BICLUSTER_ID : UPREG-40
PATHOGENS /2/ : c. albicans,s. chartarum
KNOWN DRUG TARGETS /19/ : PLA2G4A, HEXB, CTSD, CCL20, CD44, SERPINB2, GLA, PTGIR, CTNS, CCL5, PIM1, P2RY2, NEU1, PTGER4, NP, CTSB, IL1B, PTGER2, ALOX15

Gene Set	Leading Edge Genes
REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	PTGER4, CCL20, CXCL1, CCR1, PTGIR, C3AR1, CCL5, PTGER2, CXCL2, P2RY2, CCL4
KEGG LYSOSOME	HEXB, CD68, CTSD, CLN3, ATP6V0B, GNS, MCOLN1, GLA, CTSB, CTNS, HEXA, CLN5, NEU1, ATP6V0C
NETPATH IL 1 PATHWAY UP	CCL20, CXCL1, NFKBIE, NP, SERPINB2, CKS2, NFKBIA, IL1B, ZFP36, CXCL2, GJB1, CCL4
CHEMOKINE ACTIVITY	CCL20, CXCL1, CCL5, CXCL2, CCL4
NETPATH IL 3 PATHWAY UP	NFIL3, SOCS3, IL1B, CD69, FOS, PIM1, CCR1
KEGG LINOLEIC ACID METABOLISM	PLA2G4A, ALOX15
G PROTEIN COUPLED RECEPTOR BINDING	CCL20, CXCL1, CCL5, CXCL2, CCL4
REACTOME PEPTIDE LIGAND BINDING RECEPTORS	CCL20, CXCL1, C3AR1, CCL5, CXCL2, CCR1, CCL4
CHEMOKINE RECEPTOR BINDING	CCL20, CXCL1, CCL5, CXCL2, CCL4
CYTOKINE ACTIVITY	IL1RN, CCL20, CXCL1, CCL5, CXCL2, CSF2, CCL4
NETPATH IL 7 PATHWAY UP	LITAF, CXCL1, CCL5, CD44, CXCL2, CCL4
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	CCL20, CXCL1, CCL5, CXCL2, CCL4, CCR1
NEGATIVE REGULATION OF CELLULAR BIOSYNTHETIC PROCESS	BRCA1, GLA
NEGATIVE REGULATION OF BIOSYNTHETIC PROCESS	BRCA1, GLA
NCI NFAT TFPATHWAY	EGR3, EGR1, JUNB, FOS, EGR2
KEGG ASTHMA
REGULATION OF HORMONE SECRETION

Color legend
q-value	1	0.2	0.05	0.01	0.001	0.0001
Color

TABLE OF Q-VALUES

candida albicans neutrophils	stachybotrys chartarum lung	Gene Set
0.17791544	2.021267E-4	REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS
0.17728922	2.7588583E-5	KEGG_LYSOSOME
0.19693953	0.0027125722	NETPATH_IL_1_PATHWAY_UP
0.091335885	7.375062E-5	CHEMOKINE_ACTIVITY
0.10933371	3.9366656E-4	NETPATH_IL_3_PATHWAY_UP
0.09112359	0.1388137	KEGG_LINOLEIC_ACID_METABOLISM
0.1173318	1.8657849E-4	G_PROTEIN_COUPLED_RECEPTOR_BINDING
0.10786476	8.2969455E-5	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
0.08899127	7.93557E-5	CHEMOKINE_RECEPTOR_BINDING
7.5262925E-4	0.012438191	CYTOKINE_ACTIVITY
0.061718952	0.038418543	NETPATH_IL_7_PATHWAY_UP
0.17955464	5.5177166E-5	REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
0.025412852	0.15733238	NEGATIVE_REGULATION_OF_CELLULAR_BIOSYNTHETIC_PROCESS
0.022074154	0.15170847	NEGATIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS
0.035003204	0.06361532	NCI_NFAT_TFPATHWAY
0.021450594	0.09246591	KEGG_ASTHMA
0.10907822	0.16944346	REGULATION_OF_HORMONE_SECRETION