BICLUSTER_ID : <a href="#qvalue">DNREG-1088</a><BR>PATHOGENS /3/ : <a href="http://www.ebi.ac.uk/2can/genomes/bacteria/escherichia coli.html">escherichia coli</a>,<a href="http://www.ebi.ac.uk/2can/genomes/bacteria/streptococcus pneumoniae.html">streptococcus pneumoniae</a>,<a href="http://www.ebi.ac.uk/2can/genomes/bacteria/yersinia enterocolitica.html">yersinia enterocolitica</a><BR>TARGETS /15/ : <a href=drug-id-and-target-info.html#SC4MOL>SC4MOL</a>, <a href=drug-id-and-target-info.html#ACAT1>ACAT1</a>, <a href=drug-id-and-target-info.html#PDHB>PDHB</a>, <a href=drug-id-and-target-info.html#NDUFA5>NDUFA5</a>, <a href=drug-id-and-target-info.html#ACAD8>ACAD8</a>, <a href=drug-id-and-target-info.html#HADH>HADH</a>, <a href=drug-id-and-target-info.html#ALDH6A1>ALDH6A1</a>, <a href=drug-id-and-target-info.html#VDAC3>VDAC3</a>, <a href=drug-id-and-target-info.html#IDH1>IDH1</a>, <a href=drug-id-and-target-info.html#RNASE4>RNASE4</a>, <a href=drug-id-and-target-info.html#CROT>CROT</a>, <a href=drug-id-and-target-info.html#IVD>IVD</a>, <a href=drug-id-and-target-info.html#ACADM>ACADM</a>, <a href=drug-id-and-target-info.html#HSD17B4>HSD17B4</a>, <a href=drug-id-and-target-info.html#DNMT1>DNMT1</a><BR>
<table border="1">
<tbody>
<tr><th width="300">Gene Set</th><th width="900">Leading Edge Genes</th></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION">KEGG VALINE LEUCINE AND ISOLEUCINE DEGRADATION</a></td><td><a href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=93">ACAT1</a>, MCEE, <a href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=87">ACAD8</a>, <a href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=4799">HADH</a>, <a href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=7179">ALDH6A1</a>, BCKDHA, <a href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=6186">IVD</a>, <a href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=89">ACADM</a>, HMGCS1</td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/TIEN_INTESTINE_PROBIOTICS_24HR_UP">TIEN INTESTINE PROBIOTICS 24HR UP</a></td><td>KIF20A, TOP2B, <a href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=7688">NDUFA5</a>, TAF11, TMPO, CETN3, DBF4, CENPA, GTF3C2, TRIAP1, SLBP, ICMT, TOPBP1, MRPS22, BCLAF1, HSPA14, NUSAP1, CBFB, CYB5B, POP5, NR2F2, DHCR24, FBXO9, SPAST, THYN1, MRPL22, SAFB2, <a href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=8808">PDHB</a>, PIK3R4, <a href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=12674">VDAC3</a>, RPA3, ANP32E, <a href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=2976">DNMT1</a>, <a href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=10545">SC4MOL</a>, NSF, GMNN, MSH6, REEP5, PTPLB, BRD8, DNAJC9, HMGCS1, SMC4</td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/REACTOME_PEROXISOMAL_LIPID_METABOLISM">REACTOME PEROXISOMAL LIPID METABOLISM</a></td><td>SCP2, <a href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=2366">CROT</a>, AMACR, SLC25A17, <a href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=5213">HSD17B4</a>, <a href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=5382">IDH1</a></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/RICKMAN_METASTASIS_UP">RICKMAN METASTASIS UP</a></td><td>CTCF, MDM1, IPO8, DNAJC18, TFAM, SEPHS2, DNAJB11, ZFP90, RAD17, ZFP161, <a href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=7179">ALDH6A1</a>, <a href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=5382">IDH1</a>, ABCB7, <a href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=10047">RNASE4</a>, NEK9, ZMYND11</td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/CORUM_POLYCOMB_REPRESSIVE_COMPLEX_2_PRC_2">CORUM POLYCOMB REPRESSIVE COMPLEX 2 PRC 2</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/CHNG_MULTIPLE_MYELOMA_HYPERPLOID_DN">CHNG MULTIPLE MYELOMA HYPERPLOID DN</a></td><td>SLBP, FBXO21, EIF4EBP2, VPS35</td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN">MOREAUX MULTIPLE MYELOMA BY TACI DN</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN">LASTOWSKA NEUROBLASTOMA COPY NUMBER DN</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/CORUM_POLYCOMB_REPRESSIVE_COMPLEX_2_PRC2">CORUM POLYCOMB REPRESSIVE COMPLEX 2 PRC2</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/KEGG_MISMATCH_REPAIR">KEGG MISMATCH REPAIR</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/NCI_SNRNP_ASSEMBLY">NCI SNRNP ASSEMBLY</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_DN">ZHONG RESPONSE TO AZACITIDINE AND TSA DN</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA">REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/REACTOME_DNA_REPAIR">REACTOME DNA REPAIR</a></td><td></td></tr>
</tbody>
</table>
<table border="1"rules="all" VSPACE=10>
<tr><th colspan="12"<a name="qvalue">Color legend </a></th></tr>
<tr><th>q-value</th><th>-1</th><th>-0.2</th><th>-0.05</th><th>-0.01</th><th>-0.001</th><th>-0.0001</th></tr>
<tr><th>Color</th><td bgcolor="#ffffff" title="-1"></td><td bgcolor="#d9ef8b" title="-0.2"></td><td bgcolor="#a6d96a"
title="-0.05"></td><td bgcolor="#66bd63" title="-0.01"></td><td bgcolor="#1a9850" title="-0.001"></td><td title="-0.0001"
bgcolor="#006837"></td></tr>
</table>
<table border="1" VSPACE=0>
<table border="1" rules="all">
<caption align="top">TABLE OF Q-VALUES</caption>
<tbody>
<tr><th width="150">yersinia enterocolitica p60 bl6</th><th width="150">streptococcus pneumoniae d39</th><th width="150">escherichia coli</th><th>GeneSet Name</th></tr>
<tr><td align="center" width="150" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.14542</span></font></td><td align="center" width="150" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.12459</span></font></td><td align="center" width="150" bgcolor="#66bd63"><font size=1> <span style="background-color:white">-0.00397</span></font></td><td>KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION</td></tr>
<tr><td align="center" width="150" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.10678</span></font></td><td align="center" width="150" bgcolor="#66bd63"><font size=1> <span style="background-color:white">-0.00708</span></font></td><td align="center" width="150" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.08017</span></font></td><td>TIEN_INTESTINE_PROBIOTICS_24HR_UP</td></tr>
<tr><td align="center" width="150" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.10556</span></font></td><td align="center" width="150" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.12205</span></font></td><td align="center" width="150" bgcolor="#a6d96a"><font size=1> <span style="background-color:white">-0.02116</span></font></td><td>REACTOME_PEROXISOMAL_LIPID_METABOLISM</td></tr>
<tr><td align="center" width="150" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.18322</span></font></td><td align="center" width="150" bgcolor="#a6d96a"><font size=1> <span style="background-color:white">-0.03433</span></font></td><td align="center" width="150" bgcolor="#a6d96a"><font size=1> <span style="background-color:white">-0.01546</span></font></td><td>RICKMAN_METASTASIS_UP</td></tr>
<tr><td align="center" width="150" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.18139</span></font></td><td align="center" width="150" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.12724</span></font></td><td align="center" width="150" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.13647</span></font></td><td>CORUM_POLYCOMB_REPRESSIVE_COMPLEX_2_PRC_2</td></tr>
<tr><td align="center" bgcolor="#a6d96a"><font size=1> <span style="background-color:white">-0.03779</span></font></td><td align="center" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.05426</span></font></td><td align="center" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.08838</span></font></td><td>CHNG_MULTIPLE_MYELOMA_HYPERPLOID_DN</td></tr>
<tr><td align="center" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.07429</span></font></td><td align="center" bgcolor="#66bd63"><font size=1> <span style="background-color:white">-0.00101</span></font></td><td align="center" bgcolor="#a6d96a"><font size=1> <span style="background-color:white">-0.02459</span></font></td><td>MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN</td></tr>
<tr><td align="center" bgcolor="#a6d96a"><font size=1> <span style="background-color:white">-0.01597</span></font></td><td align="center" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.08443</span></font></td><td align="center" bgcolor="#a6d96a"><font size=1> <span style="background-color:white">-0.04179</span></font></td><td>LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN</td></tr>
<tr><td align="center" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.18413</span></font></td><td align="center" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.13497</span></font></td><td align="center" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.14566</span></font></td><td>CORUM_POLYCOMB_REPRESSIVE_COMPLEX_2_PRC2</td></tr>
<tr><td align="center" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.13198</span></font></td><td align="center" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.16509</span></font></td><td align="center" bgcolor="#1a9850"><font size=1> <span style="background-color:white">-0.00033</span></font></td><td>KEGG_MISMATCH_REPAIR</td></tr>
<tr><td align="center" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.16739</span></font></td><td align="center" bgcolor="#66bd63"><font size=1> <span style="background-color:white">-0.00366</span></font></td><td align="center" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.18300</span></font></td><td>NCI_SNRNP_ASSEMBLY</td></tr>
<tr><td align="center" bgcolor="#a6d96a"><font size=1> <span style="background-color:white">-0.02965</span></font></td><td align="center" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.16660</span></font></td><td align="center" bgcolor="#a6d96a"><font size=1> <span style="background-color:white">-0.01151</span></font></td><td>ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_DN</td></tr>
<tr><td align="center" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.06341</span></font></td><td align="center" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.05927</span></font></td><td align="center" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.19953</span></font></td><td>REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA</td></tr>
<tr><td align="center" bgcolor="#a6d96a"><font size=1> <span style="background-color:white">-0.02229</span></font></td><td align="center" bgcolor="#d9ef8b"><font size=1> <span style="background-color:white">-0.18550</span></font></td><td align="center" bgcolor="#1a9850"><font size=1> <span style="background-color:white">-0.00022</span></font></td><td>REACTOME_DNA_REPAIR</td></tr>
</tbody>
</table>