| Gene Set | Leading Edge Genes |
|---|
| STEIN ESRRA TARGETS | SLC31A1, MMACHC, FGFR3, ACADSB, ECSIT, ACY1, NDUFV1, SLC25A20, MRPS30, GOT2, ZHX3, COQ9, ATP5O, SUPV3L1, ACACB, MUT, PDHA1, ABCB7, PXMP4, NOL6, DSG2, NDUFS2, SUCLA2, IDH3B, DECR1, FAHD2A, COQ3, COX5A, SLC25A3, NDUFS7, HOOK1, SLC39A8, EPAS1, DLAT, MOSC2, MRPL4, SLC16A1, EHHADH, MRPL15, FDX1, NQO2, IMMT, DCI, OPLAH, OGDH, NDUFA9, ACAT1, ALDOC, TMEM111, CXCL12, AKAP1, EGLN3, PEX26, CHCHD3, TIMM50, SDHD, BMP7, NDRG2, STARD7, NNT, SEC23B, PFKM, ALDH3A2, TEX2, DNAJC11, SDHA, ETFDH, NDUFB5, UQCRFS1, NDUFS1, CLDN1, CLDN3, ANKRD28, MECR, UQCRC1, MDH1, AHCYL1, PPIF, ATP5G1, LIFR, METTL7A, CASP9, NR2F2, BRD3, OSBPL1A, LETMD1, MRPL34, HCCS, NDUFS3, MFN2, EBP, NUCB1, DLD, ATP5C1, GSTK1, SDHB, NSUN3, SNX24, OXA1L, SIRT5, ACO2, SEC14L2, BDH2, IQSEC1, MYO6, COX5B, ACAA2, ACADM, FBXL15, HIGD1A, HEXIM1, SUCLG1, CS, ATP5G3, PCYT2, IMPA1, RNF5, MIPEP, AFG3L2, SLC10A2, OPA1 |
| REACTOME DIABETES PATHWAYS | NDUFA3, NDUFV1, RPN2, NDUFA1, SLC2A2, CYC1, ENO1, SDHC, GAPDHS, NDUFA8, ATP5O, NDUFS6, HSPA5, PLG, COX6B1, PDHA1, SSR2, ALDOB, GNGT1, NDUFS2, SUCLA2, PLCB1, ATP5F1, SUCLG2, NDUFB11, ETFA, IDH3B, SLC30A6, NDUFC1, NDUFB10, COX5A, NDUFV2, SPCS3, NDUFS7, CACNA1D, IGFBP4, DLAT, IGF1, PRKACA, F2, PKLR, NDUFA10, OGDH, ETFB, NDUFA9, ALDOC, GNA14, EDEM1, UQCRQ, NDUFA4, NDUFB6, SEC61A1, COX8A, ATP5B, COX7C, SDHD, IDH2, NNT, ATP5I, PFKM, GNAS, NDUFB8, GCK, SDHA, ETFDH, NDUFB5, UQCRFS1, NDUFS1, UQCRC1, ATP5A1, DLST, DNAJC3, PRKAR2A, PDIA6, ATP5G1, ATP5J, SRPR, NDUFAB1, XBP1, ITPR2, UQCRC2, COX6C, NDUFS3, SSR1, PDHB, DLD, ERN1, ATP5C1, SDHB, GNA11, ATP5D, SSR3, IDH3G, IGFALS, ACO2, GNB3, PLCB3, NDUFB9, COX5B, RPN1, DNAJB11, COX4I1, SLC25A5, UQCRB, SUCLG1, COX6A1, CS, SRPRB |
| STEIN ESRRA TARGETS UP | SLC31A1, MMACHC, ACADSB, ECSIT, ACY1, NDUFV1, GOT2, SLC25A20, MRPS30, COQ9, ATP5O, SUPV3L1, ACACB, MUT, PDHA1, ABCB7, DSG2, PXMP4, NDUFS2, SUCLA2, DECR1, IDH3B, FAHD2A, COQ3, COX5A, SLC25A3, NDUFS7, HOOK1, EPAS1, DLAT, MOSC2, MRPL4, SLC16A1, EHHADH, FDX1, MRPL15, NQO2, DCI, IMMT, OPLAH, OGDH, ACAT1, NDUFA9, ALDOC, TMEM111, AKAP1, EGLN3, CHCHD3, PEX26, TIMM50, SDHD, NDRG2, NNT, SEC23B, PFKM, ALDH3A2, TEX2, SDHA, ETFDH, NDUFB5, UQCRFS1, NDUFS1, ANKRD28, MECR, UQCRC1, MDH1, AHCYL1, PPIF, ATP5G1, LIFR, METTL7A, CASP9, OSBPL1A, LETMD1, MRPL34, HCCS, NDUFS3, MFN2, EBP, NUCB1, DLD, GSTK1, ATP5C1, SDHB, NSUN3, OXA1L, SIRT5, ACO2, IQSEC1, BDH2, SEC14L2, COX5B, ACADM, ACAA2, FBXL15, HIGD1A, SUCLG1, CS, ATP5G3, PCYT2, IMPA1, RNF5, MIPEP, AFG3L2, SLC10A2, OPA1 |
| PARENT MTOR SIGNALING UP | PDE4DIP, PPARD, FARP1, ITGA7, PCCA, RIC8B, GSTT2, AASDHPPT, GPHN, MPDZ, GALT, GBF1, ALDH4A1, CRADD, PDHA1, ELP4, GTF3C1, TPCN1, SLC22A1, IL13RA2, ALDH7A1, HSD17B2, ACOX1, IFT140, GLUD1, PEX5, FAF1, ETHE1, ENPEP, VAPB, RDX, EEF2, SVIL, OSGEPL1, PANK4, DHCR7, G0S2, PCTK3, SREBF2, TBCCD1, GPR137, ALAD, SEC22B, USP47, NDUFS1, COPZ1, TSFM, PET112L, SYNE2, POLG, CASP9, MSH3, NIPSNAP1, CAPN7, EFNA1, KCTD2, GTF2H3, RAB5B, PPARA, HECTD3, DHODH, RORA, DBT, DEPDC5, USP34, SMARCD1, MT3, ATXN1, TSC2, CRYGD, HMGCL, DHX30, RNF123, SLC39A7, PEX6, EML3, PECR, MRPS27, AP2A2, SOLH, CALCOCO1, ADCY9, CPSF1, FDPS, TSPAN31, ECHDC2, LIAS, PDK2, PLCB1, UBE4B, BCAS3, IDH3B, NBR1, ATP9A, PDK4, PYGL, PAPSS1, L2HGDH, CECR5, CRYL1, GSTT1, RANBP9, WDR8, CDK5RAP3, ASB13, HADHA, TXNRD3, PRODH2, PDE4A, SHMT2, RAB11FIP3, MLYCD, TUSC4, ALDH3A2, PLCG1, GNAS, PEPD, SDHA, HADHB, LTBP4, CPT2, ATF7IP, CTNNB1, ESRRG, NSDHL, OXR1, DNAJC3, AHCYL1, PRKAR2A, VEGFB, ACOX3, NADSYN1, GCDH, MYST4, CEBPA, CREBL2, MSRB2, SMARCA2, FAM120C, CTH, SEPX1, GRHPR, FADD, GABARAPL1, MVD, F11, RNGTT, SNTB1, HMGCS1, WDR78 |
| KAAB HEART ATRIUM VS VENTRICLE DN | PHKA1, SLC25A20, GOT2, CYC1, COQ9, NDUFS6, MRPS18B, ECHS1, NDUFS2, ACSL3, PPP2R5C, PODXL, ACADVL, DECR1, IDH3B, HSPB6, GRM1, GPT, COX5A, SLC25A3, NDUFV2, NDUFS7, VDAC1, UBE2G1, HRAS, ALDH1L1, DCI, OGDH, CYB5A, AZGP1, ACAT1, NDUFAF1, NDUFA9, ALDOC, IPO13, HADH, HADHA, UQCRQ, ALDH5A1, SMYD2, ACADS, PRDX3, COX8A, IDH2, SDHD, HIST2H2BE, STARD7, PFKM, PCSK6, C1QBP, GNAS, SDHA, BDH1, ELAC2, MCCC2, ASS1, UQCRFS1, NDUFS1, ABLIM1, UQCRC1, TSFM, ATP5A1, METAP1, CHN2, BCKDHA, GBE1, NDUFS3, DLD, ATP5C1, SDHB, OXA1L, PHYH, ACAA2, UBE2H, C21ORF33, AK3L1, PARP1, CDH13, COX7A2, CXADR, MAOB, PCYT2, GCAT, ECH1, AFG3L2, CDH2, SGCD, OPA1 |
| CAIRO HEPATOBLASTOMA DN | CYP1A2, FAAH, MAP2K3, SLC38A4, PON1, ACADL, AGXT2L1, SRD5A1, DHRS1, VIPR1, HGD, PZP, BBOX1, PAPSS2, ACACB, MUT, UGP2, ALDOB, NFIL3, RNF125, CDC37L1, DDT, SUCLG2, FAHD2A, MASP2, FBP1, HRSP12, AGL, IL1RAP, GPR125, SLC22A1, IL13RA2, IGF1, SCP2, AKR1D1, SHMT1, ABCB11, NQO2, AZGP1, ACAT1, INSIG1, GNMT, JMJD5, GLYAT, SLC27A5, ACADS, GPD1, NDRG2, NNT, FXYD1, C8A, KMO, ETFDH, HRG, GLS2, HABP2, ASS1, CPT2, GHR, C8B, CBS, CIDEB, SLC22A7, ECM1, C6, EHD3, HAGH, HAAO, GCDH, OSBPL1A, SLC27A2, F9, ABAT, C9, PXMP2, PEMT, SLC25A15, GCGR, SARDH, SDHB, ACSL1, DHODH, HGFAC, IGFALS, MGLL, SLC10A1, NSUN6, AGXT, ACADM, ACAA2, CDA, GSTZ1, NR1I3, GRAMD1C, F11, TDO2 |
| MOOTHA PGC | MAP2K3, GSTO1, SLC31A1, ACADL, HSPD1, LRBA, VIPR1, ARIH1, SLC25A20, ABCA2, CARHSP1, HSPE1, CYC1, ENO1, INHBA, LDHA, SCD, GHITM, NDUFA8, TIMM13, ATP5O, TFB2M, SUPV3L1, CTSF, MRPS18B, PDHA1, SKIV2L, DDT, EIF4A2, GRPEL1, SUCLA2, DHX16, NDUFV2, MRPL4, TIMM44, FDX1, MRPL15, SHMT1, SGTA, ETFB, PUS1, AKAP1, GABPA, NFIX, TBL1X, NDUFB6, ACADS, PRDX3, COX7C, IDH2, NDRG2, STARD7, PFKM, SDHA, SACM1L, SLC25A11, HADHB, COMT, NDUFB5, HMGB3, ABHD5, UQCRC1, AES, FASTK, ATP5A1, AMACR, S100A1, TUFM, GCDH, STK16, OSBPL1A, NDUFAB1, MARS, ITPR2, GRSF1, MRPL34, HCCS, NDUFS3, MRPL13, NFS1, LRPPRC, DLD, PDHB, ATP5C1, SDHB, PHYH, IDH3G, RANGAP1, ACO2, MTCH2, COX5B, PTPRD, ACADM, SEPX1, MRPS2, NRP1, APBA3, CLPP, SLC25A5, TSC2, UQCRB, COX7A2, SUCLG1, COX6A1, CS, ADSS, PCYT2, RNF5, MRPL39 |
| REACTOME METABOLISM OF AMINO ACIDS | SLC38A4, SLC25A2, UROC1, ACADSB, CPS1, MCCC2, GLS2, ASS1, GOT2, TMLHE, HGD, HIBADH, IVD, PCBD1, BBOX1, GAMT, DLST, ALDH4A1, HAAO, GCDH, BCKDHA, FAH, KYNU, SLC36A1, SLC38A3, PAH, AFMID, AMDHD1, AADAT, SLC25A15, DLD, AGMAT, MCCC1, ALDH7A1, SRM, OTC, DBT, ALDH9A1, SHMT1, GLUD1, ACAT1, GSTZ1, ACAD8, SLC6A12, HPD, ALDH6A1, SLC36A2, FTCD, QDPR |
| CAIRO LIVER DEVELOPMENT DN | CPS1, PECR, KIF13B, PGM2, SP4, ITIH1, CYP2F2, CYP27A1, CES3, ABCC6, SLC38A3, FAH, GLDC, ETFA, PYGL, HSD17B2, GSTT1, SPP2, PIPOX, QPRT, COL18A1, HMGCS2, GNMT, SLC27A5, SEMA4G, CLPX, AHSG, AFM, ALDH3A2, BDH1, CROT, TST, CBS, CLDN1, BC032203, NSDHL, GAMT, DCXR, HAGH, DPYS, HAAO, GCDH, NDRG1, AQP9, TMEM30B, CSAD, ABCA8B, EBP, ACSL1, PPARA, NRN1, SLC16A2, LGALS9, PHYH, ACAA2, ACADM, LIPC, ENTPD5, APOB, KLKB1, MAOB, PCYT2, SERPINF1, GCAT, HMGCS1, ECH1, AQP1, GJB1 |
| ACEVEDO NORMAL TISSUE ADJACENT TO LIVER TUMOR DN | ACADSB, DHRS1, TM7SF2, GOT2, WBP2, PGM2, UPB1, SCD, ABHD6, ATP5O, VPS26B, FEM1A, CPSF1, ABHD14B, SLC25A22, ADH4, IGFBP4, ALDH7A1, KPNA1, DYNLL2, RDH16, OTC, SHMT1, STARD10, SDCCAG3, GLUD1, TMPRSS6, AARS, ACAT2, HPD, HADH, GNMT, TBL1X, GPD1, OSBP, SHMT2, SREBF2, REEP6, AHCY, FKBP4, TST, CBS, KHDRBS3, CLDN3, NSDHL, HAGH, INHBE, CYB5B, HAAO, NSFL1C, SRPR, PGRMC2, DNMT3L, ARMC6, NUCB1, MRPL22, SLC25A15, ZCCHC14, SDHB, DECR2, AGMAT, LDLR, RAB5B, TGDS, SLC35B1, IGFALS, BPHL, AK3, GALM, CLDN2, COX5B, RETSAT, MAOA, TBC1D16, DNAJB11, CDA, SLC25A1, ATF5, APOA4, CLPP, ZFPM1, MRPS31, HMGCS1, FASN, UCK1, HSD3B7, SRPRB |
| ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE DN | CYP1A2, FAAH, PON1, CNNM3, LECT2, VIPR1, RDH11, BBOX1, PLG, ECHS1, TNFAIP8L1, ABCB7, ALDOB, PAQR7, PMPCA, ACADVL, FBP1, VKORC1, HOOK1, SLC22A1, RAB26, TERF2IP, MARCH6, PDSS2, SPP2, GLUD1, PEX3, AZGP1, HADHA, ACADS, FTCD, GPD1, NDRG2, AFM, PROZ, DAK, EPHX2, GRAMD3, MTTP, CROT, LTBP4, GHR, INMT, MLXIPL, DLST, RELN, INHBE, MBD3, ACOX3, TMEM30B, MFN2, ARMC6, C9, GCGR, AGMAT, HGFAC, IGFALS, PROC, CDA, ATF5, ENTPD5, ADRA1B, HMGCL, SYNJ2BP, KLKB1, CDH2 |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | DALRD3, CLPB, ECE1, DMAP1, ZSWIM5, ARHGEF10L, LEPRE1, PGM2, AASDHPPT, BTRC, PCBD1, TMEM25, ZMYM4, GBF1, HYOU1, VPS26B, ECHS1, PAQR7, PHACTR4, RNF11, AHDC1, CMTM8, MLH1, DLAT, TM9SF3, SCP2, MTG1, ASRGL1, WDTC1, NME6, ATE1, JAGN1, GLUD1, FAF1, PTEN, SNX19, RDX, LARS2, LYPLA2, PRDX3, TMEM115, PCGF6, MRPL48, PANK4, CPSF3L, INTS4, TRUB1, RAF1, DHDDS, GALE, DNAJC11, NARS2, BRWD2, ELOVL1, ARCN1, ANKRD28, DPAGT1, LETM1, CASP9, OXSR1, CAPN7, AK2, CWF19L1, TMEM39B, MFN2, PI4K2A, MED8, SDHB, CMTM6, HECTD3, USP28, PARK7, RICS, LRRN1, ST3GAL3, FRAT1, IQSEC1, PPCS, DNAJC16, FBXL15, NFIA, ACAD8, DYNC2H1, ACOT7, HMGCL, DHX30, NMNAT1, HYI, TXLNA, SCAP, RBBP4, MMACHC, EPM2AIP1, GHITM, HEYL, UBIAD1, PIGG, GOLGA4, UTP11L, WDR6, KIF1B, ECD, TRAK1, ORAOV1, GRPEL1, ATG7, UBE4B, CPEB2, GPR125, SIDT2, CUL5, WHSC2, LAP3, ARHGEF12, FDX1, WDR8, TMEM126B, STK40, ACAT1, HP1BP3, IPO13, MKRN2, SDHD, WAPAL, NR2C2, CDON, SC5DL, DDX50, ATP5I, WHSC1, RPUSD4, ZFYVE20, CTNNB1, EIF2C4, PTPRF, MYCL1, NEK4, PRKAR2A, ALG8, HIF1AN, TMEM135, PEX14, SEC24C, MYST4, UBE4A, GPAM, MIB2, FRAT2, APEH, STT3B, PODN, NSUN4, FOXRED1, USP48, CYP2E1, PUM1, UBP1, PPME1, SEC22C, RSC1A1, HECTD2, CBARA1, ATM, ZMPSTE24, ODF2L, NUMA1, MRPL43, SYT7, WDR78 |
| HOSHIDA LIVER CANCER SURVIVAL DN | SC5DL, CPN1, DAD1, TM7SF2, NARS2, HABP2, GHR, HSPE1, C8B, KCNJ3, SDHC, GCKR, ACSM3, PLG, ACOT2, ANKRD46, HAAO, AOX1, F9, C9, POLRMT, GCGR, ATP5D, IGF1, PLCB3, PKLR, ALDH9A1, AKR1D1, CYB5A, GGCX, LIPC, CPOX, AARS, ARF4, TTR, HMGCL, AR, SUCLG1, PCYT2, IMPA1, TDO2, GJB1 |
| GRUETZMANN PANCREATIC CANCER DN | ONECUT1, PEX6, EPHX2, NFIB, CRYZ, ABCA3, RGN, RAF1, PRDX4, PEPD, SLC33A1, PRPSAP1, PCBD1, NR5A2, C6, GAMT, PPOX, HYOU1, PPIF, ACSM3, LSS, LGALS8, GOLGA4, PEBP1, PSEN2, DDT, SSR1, ZNF22, NUCB1, MXI1, ALDH1A1, SLC25A3, HDLBP, GRB14, LMAN1, SLC20A2, P4HB, ACO1, ACADM, ACOX1, MAOA, CYB5A, TRPV6, FKBP2, C21ORF33, GRB7, GSTZ1, MAPK8IP2, RDX, PEX1, CXCL12, SLC25A5, SNRPN, PDIA5, HHEX, EEF2, PTPRN2, F11, HSD17B4, GJB1 |
| REACTOME PYRUVATE METABOLISM AND TCA CYCLE | NNT, DLD, PDHB, SDHB, DLAT, SDHA, IDH3G, ACO2, SLC16A1, PDK1, LDHA, OGDH, SDHC, DLST, PDHA1, SUCLG1, CS, PDK2, IDH2, SDHD, SUCLA2, SUCLG2, IDH3B |
| UEDA PERIFERAL CLOCK | CHKA, MAP2K3, ONECUT1, TARS, SLC2A2, 1810058I24RIK, GALT, FGF1, FDPS, CES3, ARNTL, GLDC, IRF6, AI464131, ADH4, BC004004, NPC1, FDX1, CYP8B1, 1500035H01RIK, RORC, ETHE1, GCLC, COL18A1, GLO1, HSD3B5, TMEM150, IDI1, DHCR7, ELOVL6, PPP1R3C, FKBP4, 2700038C09RIK, HMGB3, CLDN1, AVPR1A, SLC29A1, CYB5B, APOA5, NDRG1, PSEN2, AQP9, CEBPA, TUBB2A, TFPI2, PNKD, AQP8, TLE1, PPARA, HSP90AA1, LGALS9, 1500003O03RIK, LSR, SERPINF2, DNAJB11, ATF5, HES6, 1810009A15RIK, GABARAPL1, ANP32A, ERBB3, TSC22D1, FASN, HMGCS1, ELOVL5, FBXO8 |
| KEGG ARGININE AND PROLINE METABOLISM | AGMAT, ALDH3A2, ACY1, ALDH7A1, CPS1, SRM, LAP3, GLS2, ASS1, OTC, GOT2, ALDH9A1, GLUD1, GAMT, PYCRL, ALDH4A1, ALDH2, NOS3, MAOB, PRODH2 |
| COULOUARN TEMPORAL TGFB1 SIGNATURE DN | CHKA, GSTO1, ALDH3A2, CPN1, SLC26A1, DHRS1, TM7SF2, HABP2, CXXC5, CBS, HIPK2, HMGA2, GJB2, ALDOB, FDPS, ACSL3, ACVR1, JAG1, SLC2A8, GPT, PPAP2B, LDLR, IGFBP4, PCDH1, SCP2, MOSPD3, RSC1A1, CDA, SEPX1, ENTPD5, COL18A1, EPS8L2, CXCL12, IDH1, CXADR, PCYT2, SLC25A13, SVIL, HMGCS1, GPD1, DHCR7 |
| CHIANG LIVER CANCER SUBCLASS CTNNB1 UP | INSIG2, RHOBTB1, ALDH3A2, BMP4, PDK1, HIBADH, CTNNBL1, ABHD6, MME, AMACR, DCXR, DPP4, AOX1, NAGS, AQP9, IRS1, AXIN2, GPAM, TMEM64, PDK4, MTHFD1, AADAC, SLC16A1, PTPRG, SEC14L2, CLDN2, ALDH1L1, ABCB11, CYP8B1, SLC25A30, ABCG2, BIK, HSDL2, AQP11, SLC6A12, HPD, ACSL5, SULT1B1, GLYAT, AR, TBX3 |
| RAMALHO STEMNESS UP | SEC23A, GSTA4, RRN3, GFER, IARS2, SH3D19, ARIH1, PIGX, ZMYM4, UTP20, BYSL, PAFAH2, RABGGTB, SUCLG2, LSM2, GCLM, HRSP12, CAD, RAB18, ALDH7A1, PLA2G6, LAPTM4B, JAGN1, NDUFAF1, ACAT2, AW549877, GLO1, MRPS10, XPOT, UMPS, IARS, YAP1, ELOVL6, MRPL17, PSMD11, PRPSAP1, PRPF6, RPUSD4, GHR, LAS1L, D030029J20RIK, ARCN1, GAS2, ANKRD17, TOM1L1, PDCD2, RAD23B, PPA1, DNAJB6, USP10, MKI67IP, NDUFAB1, MRPL45, TNPO1, MRPL34, COPS7A, LIG3, ACADM, USP9X, MRPS2, PSMD12, RNF4, GCAT, MRPS31, ZFP213, LAPTM4A, FBXO8 |
| SCHUHMACHER MYC TARGETS UP | NME1, TBL3, ABCE1, CAD, BOP1, ACSL1, MTHFD1, PRDX4, AHCY, DHODH, SRM, SLC16A1, FKBP4, HSPE1, LDHA, POLD2, FABP5, AK3L1, PEBP1, AKAP1, GPD1L, CYP51A1, SORD, FASN, TRAP1, IARS |
| KEGG PYRUVATE METABOLISM | DLD, PDHB, ACOT12, ALDH3A2, DLAT, ALDH7A1, PKLR, ALDH9A1, ACAT1, MDH1, HAGH, ACACB, ACAT2, ACSS2, PDHA1, ALDH2, GLO1, LDHD |
| REACTOME METABOLISM OF VITAMINS AND COFACTORS | GSTO1, NMNAT3, PANK3, MTHFD1, RFK, PPCS, SHMT1, FPGS, AASDHPPT, CYB5A, SLC25A16, QPRT, COASY, TPK1, SLC23A1, NADSYN1, CYB5R3, FASN, NMNAT1, PANK4, PANK1, SLC19A2 |
| KEGG GLYCOLYSIS GLUCONEOGENESIS | FBP1, DLD, PDHB, ADH4, PFKM, ALDH3A2, DLAT, ALDH7A1, GCK, GALM, ALDH9A1, PGM2, PKLR, ENO1, ALDOC, ACSS2, ALDH2, PDHA1, ALDOB, ADH1A, G6PC |
| KEGG LYSINE DEGRADATION | AADAT, ALDH3A2, ALDH7A1, TMLHE, EHHADH, ALDH9A1, AASDHPPT, PIPOX, ACAT1, BBOX1, DLST, ACAT2, HADHA, ECHS1, HADH, ALDH2, GCDH |
| WELCSH BRCA1 TARGETS 1 DN | DDX11, SCAP, BOP1, FGFR3, NARS, GTF3C2, FKBP4, USP5, AGPAT2, NSDHL, EMG1, RXRA, HCFC1, SLC29A1, POLG, SKIV2L, EIF4G1, BYSL, NDRG1, SEC24C, DDT, PMPCA, POLRMT, CAD, MTHFD1, HDLBP, VDAC1, SRM, PPM1F, PSMD1, PRKACA, ATIC, AP3D1, ALG3, SCRIB, FDFT1, RASSF7, FASN, TRAP1, U2AF1, SLC39A7 |
| KEGG GLYCINE SERINE AND THREONINE METABOLISM | AGXT2, GAMT, SHMT2, DLD, SARDH, GNMT, DMGDH, SRR, MAOB, GCAT, SHMT1, AGXT, CBS, GLDC, PIPOX |
| KEGG ALANINE ASPARTATE AND GLUTAMATE METABOLISM | AGXT2, GPT, ALDH4A1, CPS1, ALDH5A1, NIT2, GLS2, ADSS, ASS1, ASPA, GOT2, ACY3, AGXT, GLUD1, ABAT |
| KEGG TYROSINE METABOLISM | TPO, ADH4, LCMT2, COMT, GOT2, HGD, MIF, MAOA, HEMK1, GSTZ1, HPD, AOX1, DCT, DDC, MAOB, FAH, ADH1A, NAT6, LCMT1 |
| MCBRYAN PUBERTAL BREAST 4 5WK DN | PEX6, MLX, RBBP4, TMEM109, CABC1, REEP6, APOC2, PPP1R3C, ETFDH, PRKCE, PDK1, PCMTD1, ACAD9, CSNK2A1, CARHSP1, MLXIPL, HIPK2, 9530058B02RIK, FABP5, AHCYL1, KCNK3, ATPAF2, EIF4G1, NFIC, 4933439F18RIK, LETMD1, GYK, NID2, ATP6V0A1, UBE4A, HCCS, GPAM, JAG1, HIST2H3C2, SLC25A10, ACADVL, IDH3B, RAB5B, ACSL1, ATP5D, IGFBP4, DLAT, SLC16A2, IGFALS, MTCH2, ACO2, EHHADH, COQ5, DBT, ACAA2, IMMT, DCI, ACAT1, BMP1, PPARGC1B, SUCLG1, ACLY, ECH1, GPD1 |
| REACTOME CITRIC ACID CYCLE | NNT, DLD, SDHB, SDHA, IDH3G, ACO2, OGDH, SDHC, DLST, SUCLG1, CS, SUCLA2, SDHD, IDH2, SUCLG2, IDH3B |
| KEGG AMINOACYL TRNA BIOSYNTHESIS | AARS, LARS2, IARS2, TARS, NARS2, SARS2, DARS2, MARS, YARS2, DARS, IARS, MTFMT, CARS |
| KIM MYC AMPLIFICATION TARGETS UP | PRDX6, NME1, HSPD1, ALDH3A2, PHKA1, GOT2, PGM2, ENO1, NDUFS1, NME2, EEF2K, ATP2B2, PDHA1, COX6B1, DHX33, CDKAL1, ETFA, MRPL13, SLC19A2, C7ORF16, PEMT, MXI1, LRPPRC, NUDT11, AGL, ANGPTL2, EBPL, PARK7, SLC16A1, IGSF11, LYPLA1, CYP7B1, HSD17B12, MRPS2, C21ORF33, MRPL50, MCC, SLC25A5, SUCLG1, PGRMC1, POLR3K, ATP5B, ACLY, SGCD, MTFMT |
| REACTOME TRNA AMINOACYLATION | AARS, LARS2, IARS2, TARS, NARS2, SARS2, DARS2, MARS, YARS2, DARS, IARS, CARS |
| SHEN SMARCA2 TARGETS UP | HERC2, ZFAND6, IDS, FBXO3, AASDHPPT, CUL4A, CREG1, ATP5O, MAP4K5, ITFG1, LGALS8, CNBP, IDE, SUCLA2, PPP2R5C, SUCLG2, NBR1, GTF2H5, ATG3, PREPL, TTRAP, MLH1, PHKB, CUL5, CSE1L, UBE2G1, NFYB, SEC63, TMEM41B, PCMTD2, CUL4B, TMEM126B, PEX3, HSDL2, SRP9, AGGF1, SERINC1, RDX, TSN, FTO, PJA2, NDUFB6, CBX1, PEX19, SDHD, RAB1A, TWSG1, TRIP4, FEM1C, NNT, SEPHS1, INSIG2, RAF1, PEX11B, DHX29, MTO1, RIOK3, ARHGAP29, SS18, BRWD2, FBXW2, RBM16, NUMB, ANKRD17, RAB14, LANCL1, RMND5A, ST13, NSFL1C, TMEM80, TMEM135, OSBPL1A, CAPN7, DDX46, TNPO1, GBE1, UQCRC2, ACVR1, ZDHHC6, TLK1, UBR2, RAB23, PDHB, GTF3C3, UPF3B, MOCS2, SMARCA2, FUSIP1, NCOR1, USP9X, CUL2, DERA, ATXN1, TSNAX, PRKD3, PSMD12, SUCLG1, PURA, PCNP, ANP32A, ADSS, H2AFV, KIFAP3, NCKAP1, RHOT1, LAPTM4A, PKN2 |
| MCBRYAN PUBERTAL BREAST 6 7WK UP | 2610507B11RIK, NFIB, RBBP4, GNAS, CAR8, DHX36, PCMTD1, CSNK2A1, MLXIPL, IGJ, HIPK2, ECM1, ATP5A1, EHD3, PIK3R1, KCNK3, EIF4G1, NFIC, NDUFAB1, 4933439F18RIK, NDST1, ATP6V0A1, UBE4A, GPAM, JAG1, DAPK1, HIST2H3C2, SLC25A10, PDAP1, TMEM79, PANK3, RAB5B, IGFBP4, PCYT1A, HDLBP, UBTF, IGFALS, SOX9, CRK, ZBTB20, XIST, STAT5B, PTEN, VAPB, TBL1X, NFIX, SEC61A1, FADS2, ACLY, TCF7, GPD1, RASSF3, NR2C2 |
| KEGG PPAR SIGNALING PATHWAY | FABP1, PPARD, ACADL, PPARA, ACSL1, SCP2, CPT2, EHHADH, FABP2, ACADM, ACOX1, CYP8B1, SCD, SLC27A4, FABP5, RXRA, HMGCS2, ACSL5, ACOX3, APOA5, APOC3, SLC27A5, SLC27A2, ACSL3, CYP27A1, FADS2 |
| RODWELL AGING KIDNEY NO BLOOD DN | GNAS, MTO1, HADHB, GOT2, GHR, FBXO3, NDUFS1, ESRRG, ABCA5, PET112L, ATP5A1, AHCYL1, PEBP1, MUT, TMEM80, DSG2, AK2, COX6C, TSPAN7, RALGPS1, LRPPRC, PRKAA2, DLAT, PHYH, DBT, KLHL24, USP9X, CYB5A, MAK10, SRR, ATP5G3, COX8A, COX7C, BMP7 |
| VANTVEER BREAST CANCER ESR1 UP | FAAH, RAB11FIP3, PCSK6, ABCA3, ACADSB, LRBA, HDAC11, RNF103, MCCC2, MRPS27, CXXC5, KIF13B, SOX12, WDR6, SREBF1, GPD1L, IRS1, COX6C, FARP2, ABAT, FBP1, CHD6, IGFBP4, SPEF1, LRIG1, SEC14L2, STARD10, DCI, HEXIM1, FOXA1, CELSR1, HMGCL, ERBB3, ESR1, HSD17B4, QDPR, ELOVL5 |
| YAMASHITA LIVER CANCER STEM CELL DN | CYP1A2, SOD1, ACSL1, C8A, HRG, SLC10A1, APOC4, MASP1, C8B, ALDH1L1, ABCB11, NQO2, CYP8B1, C6, FABP5, ALDH6A1, NR1I3, ACSL5, APOA5, AOX1, ACSL3, SLC27A2, F9, KLKB1, ALDH8A1, F11, ESR1, MASP2 |
| LANDIS ERBB2 BREAST PRENEOPLASTIC DN | CHPT1, MCCC1, NDUFV1, ALDH1A7, SCP2, CPT2, ALAD, GHR, PGM2, ACAA1B, ACAA2, ABHD5, ADIPOR2, GSTZ1, CXCL12, PDHA1, CES3, GPD2, NDUFAB1, GBE1, GPAM, PTPRB, UCK1, DECR1 |
| KEGG BETA ALANINE METABOLISM | ALDH3A2, DPYS, ALDH7A1, ECHS1, HADHA, ALDH2, SRM, EHHADH, ALDH9A1, ACADM, UPB1, ABAT, DPYD |
| REACTOME REGULATION OF LIPID METABOLISM BY PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA | ACSL1, PPARA, MTTP, SCP2, CPT2, NCOR1, EHHADH, SLC2A2, ACOX1, ACADM, SCD, RXRA, APOA5, FADS1, TBL1X, SREBF1, FADS2, FASN, SLC10A2 |
| KEGG CYSTEINE AND METHIONINE METABOLISM | CTH, BHMT, AHCYL1, MTAP, AHCY, DNMT3B, SRM, GOT2, DNMT3L, CBS, LDHA, MPST, TAT |
| REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | ACAT1, DLD, ACAD8, ACADSB, MCCC1, ALDH6A1, MCCC2, BCKDHA, HIBADH, DBT, IVD |
| CORUM RESPIRATORY CHAIN COMPLEX I INCOMPLETE INTERMEDIATE MITOCHONDRIAL | NDUFA9, NDUFS6, NDUFV2, NDUFS7, NDUFB8, NDUFV1, NDUFS2, NDUFA10, NDUFS1 |
| HOSHIDA LIVER CANCER SUBCLASS S2 | CHKA, FGFR4, SEPHS1, SREBF2, FGFR3, TTC3, AHCY, GTF3C2, CSNK2A1, CTNNB1, CUL4A, SLC6A2, NR5A2, ABCD3, GBF1, H1F0, ATP2B2, BRD3, EIF4A2, ATP5F1, NR2C1, POFUT1, CSE1L, IGF2R, FLNB, GLUD1, GRLF1, PTOV1, SLC6A5, ITIH2, ATF2, ERBB3, CXADR, ATM, PHKA2, PRDX3, EIF4B, ABCB10, SNTB1, IDI1 |
| LEE LIVER CANCER ACOX1 DN | CA3, ATP2A1, IL1RAP, RGN, PPP1R3C, MCM3AP, LECT2, OTC, APOC4, MASP1, HGD, KHK, CYP7B1, PIPOX, EGFR, LIPC, ITIH1, CPOX, SLC29A1, GSTA3, HPD, DPP4, SLC27A5, PAH, SLCO2B1, G6PC |
| NCI CITRIC ACID CYCLE TCA CYCLE | SDHB, SDHA, SUCLG1, CS, IDH3G, ACO2, SUCLA2, SDHD, SUCLG2, SDHC, IDH3B |
| KEGG HISTIDINE METABOLISM | HEMK1, UROC1, ALDH3A2, ALDH7A1, ALDH2, DDC, MAOB, ASPA, FTCD, ALDH9A1, ACY3, AMDHD1 |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 14 | NME1, NSUN2, 2310061I04RIK, NARS, CCT3, CARM1, MME, APEX1, METAP1, FGF1, VCL, SSR2, EIF4G1, PREP, SMARCA4, GALK1, SSR1, CAD, SSR3, HDLBP, PDLIM3, SNRPD3, PSMD1, GALM, RPN1, TMEM147, GPS1, PTOV1, WDR74, COL18A1, 1810009A15RIK, GORASP2, SMYD2, NSBP1, CS, SEC61A1, LMAN2, PSME4, NDE1, SLC39A7 |
| SCHLOSSER MYC TARGETS REPRESSED BY SERUM | CBX3, HSPD1, IARS2, TARS, RAN, SEC31A, HSPE1, AASDHPPT, COX11, PDIA6, RMND5A, ALG8, CNBP, NR2F2, USP10, PMPCB, FBXO9, RABGGTB, ATP5C1, TGDS, SLC16A1, UBE2G1, ATP13A3, LYPLA1, CTAGE5, ZMPSTE24, NDUFB6, ADSS, HDAC2, XPOT, U2AF1, AFG3L2, IARS, DARS |
| MOOTHA TCA | SDHB, SDHA, SUCLG1, CS, IDH3G, ACO2, IDH2, SUCLA2, SDHD, SDHC, OGDH, IDH3B |
| CORUM RESPIRATORY CHAIN COMPLEX I BETA SUBUNIT MITOCHONDRIAL | NDUFB3, NDUFB8, NDUFA4, NDUFB6, NDUFAB1, NDUFB9, NDUFB2, NDUFB5, NDUFB11, NDUFB10 |
| RICKMAN METASTASIS UP | MAGEH1, SNED1, PFKM, NUDT7, GNAS, TMLHE, TTC17, RPE, LMAN2L, NDUFS1, LRRC23, EPM2AIP1, PLEKHA5, YIPF6, COX11, MPDZ, LOH12CR1, GLRX5, MTERFD3, MRPL44, ACACB, TTLL5, ST13, ABCB7, MYST1, SEC14L4, FARP2, NBR1, LRP6, ATP9A, IPO8, GPR19, DTX4, PSMD1, BDH2, SCFD2, SEPHS2, ALS2, JAGN1, DNAJB11, CDK5RAP3, HSD17B12, METTL7B, DYRK2, DCUN1D1, ACVR2A, PXDN, ALDH6A1, MOBKL1A, IDH1, SNRPN, AKAP1, PGRMC1, GCAT, YARS2, MRPS35 |
| REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | NR4A3, PPARD, PPARA, THRB, RORA, ESRRG, NR2F6, RORC, NR5A2, NR1I3, NR3C1, AR, THRA, ESR1, NR2C1, NR2C2, NR6A1 |
| KEGG SELENOAMINO ACID METABOLISM | CTH, HEMK1, AHCYL1, PAPSS2, SEPHS1, LCMT2, PAPSS1, AHCY, MARS, CBS, SEPHS2, SCLY, LCMT1 |
| KEGG RETINOL METABOLISM | CYP1A2, ALDH1A1, RDH10, DHRS4, UGT2A3, RETSAT, ADH4, ADH1A, RDH11, RDH5 |
| HOSHIDA LIVER CANCER LATE RECURRENCE DN | CHRNA5, PEMT, SC5DL, ATP5D, COBLL1, TEK, THRB, ALAD, NAP1L3, FDX1, SLC35D1, GCHFR, MAOA, CDA, LCAT, MME, HIST1H1T, PPOX, GCKR, HAAO, DHRS2, ZBTB5, PCYT2 |
| CHIANG LIVER CANCER SUBCLASS POLYSOMY7 UP | PEMT, TLE2, GCGR, PYGL, SLC22A1, GCK, PEPD, SLC16A2, SRD5A1, DHRS1, CROT, HAPLN4, IGFALS, CIDEB, CLDN3, POLD2, ABCB4, MAP1LC3A, HAAO, CHN2, PTK6, ADCY1, RHOU, PRSS8, ARMC6 |
| REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | NARS2, SARS2, DARS2, YARS2, LARS2, FARS2, IARS2 |
| REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | APOE, SAR1B, LIPC, APOA2, LDLR, APOA4, APOB, APOC2, APOA5, APOC3, MTTP, P4HB, APOA1 |
| REACTOME LIPOPROTEIN METABOLISM | APOE, SAR1B, LIPC, BMP1, APOA2, LDLR, APOB, APOA4, APOC2, APOA5, APOC3, MTTP, P4HB, APOA1 |
| KEGG LIMONENE AND PINENE DEGRADATION | ALDH3A2, ALDH7A1, ECHS1, HADHA, ALDH2, EHHADH, ALDH9A1, NAT6 |
| NCI CHYLOMICRON MEDIATED LIPID TRANSPORT | APOE, SAR1B, LIPC, APOA2, LDLR, APOB, APOC2, APOA5, APOC3, MTTP, P4HB, APOA1 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | ACADL, ECHS1, HADH, HADHA, HADHB, ACADS, ACADM, DCI, ACADVL, DECR1 |
| BIOCARTA ETC PATHWAY | UQCRC1, ATP5A1, GPD2, NDUFA1, SDHB, SDHD, SDHC, SDHA |
| NCI MITOCHONDRIAL TRNA AMINOACYLATION | NARS2, SARS2, DARS2, YARS2, LARS2, FARS2, IARS2 |
| TOMLINS PROSTATE CANCER UP | AMACR, CACNA1D, EEF2, MCCC2, CXADR, PPIB, MYO6, CANX, HSD17B4, DAPK1 |
| KAPOSI LIVER CANCER POOR SURVIVAL DN | EPHX1, ALDH1A1, EPHX2, GSTT1, PIK3R1, ALDH6A1 |
| KEGG PHENYLALANINE METABOLISM | DDC, PRDX6, MAOB, GOT2, PAH, NAT6, HPD |
| NCI NICOTINATE METABOLISM | NMNAT3, HAAO, NADSYN1, KMO, KYNU, AFMID, NMNAT1, TDO2, QPRT |
| JAERVINEN AMPLIFIED IN LARYNGEAL CANCER | GTPBP8, PSCA, PSMB5, ASH2L, MCCC1, NR1I3, COQ4, DUSP16, FADD, SNRPD3, GNPAT, MGAM, ESR1, NDUFB5 |
| KEGG STEROID HORMONE BIOSYNTHESIS | HSD3B2, STS, SRD5A1, HSD17B2, UGT2A3, COMT, AKR1D1, HSD17B12, CYP7B1 |
| PENG RAPAMYCIN RESPONSE DN | TMEM109, PFKM, TGDS, MMP15, SRM, CSE1L, HSPE1, ATF5, NDUFA9, BMP1, HYOU1, SLC29A1, JTB, ALDH4A1, ATP5G1, CHUK, ATP5G3, RABGGTB, HCCS, FASN, COPB2 |
| BIOCARTA KREB PATHWAY | CS, ACO2, MDH1, IDH2, SUCLA2, OGDH, SDHA |
| KHETCHOUMIAN TRIM24 TARGETS DN | ALDH1A1, SLC10A1, FGF1, PRLR, AR |
| REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | SLC6A13, SLC18A2, SLC6A12, SLC6A5, SLC6A2, SLC6A9 |
| KEGG ASCORBATE AND ALDARATE METABOLISM | UGT2A3, ALDH9A1, ALDH3A2, ALDH7A1, ALDH2 |
| REACTOME PEROXISOMAL LIPID METABOLISM | AMACR, HACL1, ACOT8, ACOX3, IDH1, PHYH, CROT, SLC27A2, SCP2, ACOX1, HSD17B4 |
| NCI GLUCOSE REGULATION OF INSULIN SECRETION | SDHB, SLC2A2, SDHD, SDHC, SDHA |
| YAMASHITA LIVER CANCER WITH EPCAM DN | GSTA3, HMGCS2, APOC1, HRG, SERPINC1, ECHDC2, ALDH1L1, SCLY |
| REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | CPT2, SLC25A20, PRKAG1, ACACB, ACSL1, PRKAA2, STK11 |
| NCI OXIDATIVE DECARBOXYLATION OF PYRUVATE TO ACETYL COA BY PYRUVATE DEHYDROGENASE | DLD, PDHB, DLAT, PDHA1 |
| NCI PYRUVATE METABOLISM AND TCA CYCLE | SDHB, SDHD, SDHC, SDHA |
| NCI MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS | HADHB, ACADS, ACADL, ACADM, ECHS1, HADH, HADHA |
| SCHLOSSER MYC AND SERUM RESPONSE SYNERGY | EIF4A1, PYCR1, KHSRP, RNF126, NCLN, SRM, SCAMP3, MTA1, FPGS, FRAT2, ZNF22, SNRPA, ARMC6, SGTA |
| NCI PHENYLALANINE AND TYROSINE CATABOLISM | FAH, GSTZ1, HGD, PAH, HPD, PCBD1, QDPR |
| NCI MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS | HADHB, ACADL, ACADM, DCI, HADHA, DECR1 |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 10 | AP3M1, RRBP1, NSUN2, DAD1, HBB-B1 /// HBB-B2, SLC1A4, POLR2L, RPN2, LASS2, TM9SF3, RANGAP1, FKBP4, CANX, BRP44, HSPE1, UFM1, LDHA, ARCN1, PEX13, PXMP3, FKBP2, TMED2, CDK2AP2, 2210016F16RIK, ADK, TIMM23, SEC61A1, 2310001A20RIK, YIPF5, EIF1B, BCKDHB, PRDX1 |
| NCI CARNITINE SYNTHESIS | BBOX1, TMLHE, ALDH9A1, SHMT1 |
| KEGG BIOSYNTHESIS OF UNSATURATED FATTY ACIDS | ACOT1, ACOT2, ELOVL6, ACOX3, ELOVL2, HADHA, PECR, FADS1, FADS2, ACOT4, ACOX1, ELOVL5, HSD17B12, SCD |
| CORUM RESPIRATORY CHAIN COMPLEX I EARLY INTERMEDIATE NDUFAF1 ASSEMBLY MITOCHONDRIAL | NDUFB6, NDUFA9, NDUFAF1, NDUFS7, NDUFS3 |
| NCI REGULATION OF PYRUVATE DEHYDROGENASE COMPLEX PDC | DLD, PDHB, PDK2, DLAT, PDHA1 |
| LEE LIVER CANCER | C6, PEMT, PPAP2B, ADH4, UROC1, PLG, C8A, SLC22A1, APOF, TTR, IGFALS, LDHD, ACADS, CYP2E1, C8B, NDRG2 |
| LEE LIVER CANCER TOP50 | C6, PEMT, PPAP2B, ADH4, UROC1, PLG, C8A, SLC22A1, APOF, TTR, IGFALS, LDHD, ACADS, CYP2E1, C8B, NDRG2 |
| DING LUNG CANCER MUTATED SIGNIFICANTLY | FGFR4, PAK3, EPHA5, GNAS, KDR, ATM, SLC38A3, PTPRD, INHBA, STK11, EGFR |
| BOYAULT LIVER CANCER SUBCLASS G12 DN | GCKR, HGD, FAH, ALDH1L1, GSTA3, QDPR, ACSL5, ABCG2 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS | AMACR, SLC27A5, SLC27A2, SCP2, CYP27A1, AKR1D1, ABCB11, HSD17B4, HSD3B7, CYP8B1, CYP7B1 |
| WILLIAMS ESR2 TARGETS UP | KIF21A, OXR1, RG9MTD2, HMGCL, ALG14, CYB5R3, UQCRFS1, GSTT2 |
| NCI BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA | HADHB, ACADM, ECHS1, HADH, HADHA |
| LUCAS HNF4A TARGETS UP | TRAF4, AGXT2L1, ACY1, DHRS1, ETFDH, KIF13B, SLC25A20, SLC35D1, ACOX1, CIDEB, ATP7B, AKAP1, ALDH5A1, ERBB3, PRKCSH, KIFAP3, ACADVL, EBP |
| BIOCARTA NUCLEARRS PATHWAY | CYP1A2, PPARD, ABCB4, ABCB11, PPARA, NR1I3 |
| NCI BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA | HADHB, ACADS, ECHS1, HADH, HADHA |
| BIOCARTA EIF4 PATHWAY | PTEN, PIK3R1, EIF4G1, PIK3CA, EIF4A2, GHR, IRS1, PDK2, MAPK1 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | AMACR, SLC27A5, SLC27A2, CYP27A1, SCP2, AKR1D1, ABCB11, HSD17B4, HSD3B7, CYP8B1 |
| KEGG TERPENOID BACKBONE BIOSYNTHESIS | ACAT1, ACAT2, DHDDS, HMGCS2, FDPS, MVD, IDI1, PMVK, PDSS2, HMGCS1, MVK |
| REACTOME METABOLISM OF BILE ACIDS AND BILE SALTS | AMACR, SLC27A5, SLC27A2, SCP2, CYP27A1, SLC10A1, AKR1D1, HSD17B4, ABCB11, SLC10A2, CYP8B1, CYP7B1, HSD3B7 |
| NCI BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA | HADHB, ACADM, ECHS1, HADH, HADHA |
| NCI PROPIONYL COA CATABOLISM | PCCA, MCEE, PCCB, MUT |
| NCI SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | AMACR, SLC27A5, SLC27A2, CYP27A1, SCP2, AKR1D1, ABCB11, HSD17B4, HSD3B7, CYP8B1 |
| NCI LYSINE CATABOLISM | AADAT, ECHS1, HADH, GCDH |
| KEGG GLYCOSAMINOGLYCAN BIOSYNTHESIS HEPARAN SULFATE | B3GAT1, EXTL1, B3GAT3, EXTL2, HS3ST2, EXT2, HS3ST3B1, XYLT2, NDST1, GLCE, B3GAT2 |
| NCI LEUCINE CATABOLISM | MCCC2, IVD, MCCC1 |
| KEGG MATURITY ONSET DIABETES OF THE YOUNG | NR5A2, ONECUT1, NEUROG3, SLC2A2, PKLR, GCK, HHEX |
| KEGG GLYOXYLATE AND DICARBOXYLATE METABOLISM | CS, HAO1, ACO2, MDH1, ACO1, MTHFD1, AFMID, HYI |
| KEGG PRIMARY BILE ACID BIOSYNTHESIS | AMACR, SLC27A5, CYP27A1, SCP2, AKR1D1, HSD17B4, HSD3B7, CYP7B1, CYP8B1 |
| NCI FORMATION OF ACETOACETIC ACID | ACAT1, HMGCS2, HMGCL |
| WANG RESPONSE TO FORSKOLIN UP | ACSL3, SPCS3, INSIG1, GNAI3, EVI5, FADS1, DYNLL2 |
| KEGG N GLYCAN BIOSYNTHESIS | DAD1, DOLPP1, GANAB, RPN2, DPM1, MGAT5B, ALG12, RPN1, MAN1B1, MAN2A2, ALG3, B4GALT2, ALG6, MGAT1, DPAGT1, ALG8, ALG14, STT3B, ALG2, MGAT3 |
| PETRETTO HEART MASS QTL CIS UP | PLEKHB1, RAB14, ADRA1B, DHDDS, BPHL, RPUSD4, CSNK2A1, TST |
| NCI BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA | HADHB, ACADL, ECHS1, HADH, HADHA |
| CORUM FRATAXIN COMPLEX | HSPD1, AFG3L2, SDHA |
| SCHLOSSER MYC TARGETS AND SERUM RESPONSE DN | HDGF, RPP40, FABP5, MXI1, PRDX4, AKAP1, BYSL, PDIA5, CSE1L, RAN, FTSJ1, LDHA, BAG2 |
| NCI ALPHA OXIDATION OF PHYTANATE | SLC27A2, HACL1, IDH1, PHYH |
| NIKOLSKY BREAST CANCER 1Q21 AMPLICON | RORC, SHC1, MRPL9, FDPS, SCAMP3, EFNA1, PKLR, PMVK, TDRKH, DCST2 |
| NCI BETA OXIDATION OF PRISTANOYL COA | CROT, SCP2, ACOX2, AMACR, ACOT8, HSD17B4, ACOX3 |
| REACTOME VITAMIN B5 (PANTOTHENATE) METABOLISM | COASY, PANK3, PPCS, FASN, AASDHPPT, SLC25A16, PANK4, PANK1 |
| NCI HISTIDINE CATABOLISM | FTCD, UROC1, AMDHD1 |
| KEGG PENTOSE AND GLUCURONATE INTERCONVERSIONS | CRYL1, XYLB, DHDH, UGT2A3, DCXR, RPE, UGP2 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | CYP27A1, SLC27A2, SLC27A5, AMACR, AKR1D1, CYP8B1, HSD3B7 |
| NCI SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL | CYP27A1, AKR1D1, CYP7B1, CYP8B1, HSD3B7 |
| REACTOME CELL CELL ADHESION SYSTEMS | PARD3, CLDN12, CDH10, PVRL3, CLDN2, MLLT4, CTNNB1, CLDN3, CLDN1, CLDN4, CDH13, CDH7, CLDN5, CDH2, PVRL1, CLDN6, CRB3 |
| KEGG PROTEIN EXPORT | SPCS3, HSPA5, SRP9, SEC61B, OXA1L, SPCS2, SRPR, SEC61A1, SEC63, SRP72, IMMP2L, SRP68, SRPRB |
| NCI SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | CYP27A1, SLC27A2, SLC27A5, AMACR, AKR1D1, CYP8B1, HSD3B7 |
| NCI SYNTHESIS OF BILE ACIDS AND BILE SALTS | AMACR, CYP27A1, SLC27A2, SLC27A5, AKR1D1, CYP7B1, CYP8B1, HSD3B7 |
| NCI TRYPTOPHAN CATABOLISM | KYNU, AFMID, HAAO, TDO2, KMO |
| REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | ATP5O, ATP5A1, ATP5I, ATP5C1, ATP5D, ATP5G1, ATP5J, ATP5B, ATP5F1 |
| REACTOME RECYCLING OF BILE ACIDS AND SALTS | SLC27A5, SLC10A1, ABCB11, SLC10A2 |
| REACTOME COPI MEDIATED TRANSPORT | ARFGAP1, GBF1, ARCN1, COPB2, COPZ1, COPA, COPG, COPB1 |
| NCI COPI MEDIATED TRANSPORT | ARFGAP1, GBF1, ARCN1, COPB2, COPZ1, COPA, COPG, COPB1 |
| NCI RECYCLING OF BILE ACIDS AND SALTS | SLC27A5, SLC10A1, ABCB11, SLC10A2 |
| ZIRN TRETINOIN RESPONSE WT1 DN | ECE1, TYSND1, AQP1, TLR5 |
| NCI FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | ATP5O, ATP5A1, ATP5I, ATP5C1, ATP5D, ATP5G1, ATP5J, ATP5B, ATP5F1 |
| KEGG GLYCOSYLPHOSPHATIDYLINOSITOL GPI ANCHOR BIOSYNTHESIS | GPAA1, PIGC, GPLD1, PIGG, PIGL, PIGY, PIGS, PIGX, PIGB, PIGH |
| BIOCARTA EIF PATHWAY | |
| NCI REGULATION OF LIPID METABOLISM BY PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA PPARALPHA | |
| WANG RESPONSE TO ANDROGEN UP | |
| BOYAULT LIVER CANCER SUBCLASS G12 UP | |
| KEGG GLYCEROLIPID METABOLISM | |
| REACTOME TIGHT JUNCTION INTERACTIONS | CLDN4, PARD3, CLDN12, CLDN5, CLDN2, CLDN1, CLDN3, CRB3, CLDN6 |
| VANHARANTA UTERINE FIBROID WITH 7Q DELETION DN | |
| KEGG VALINE LEUCINE AND ISOLEUCINE BIOSYNTHESIS | |
| FARMER BREAST CANCER APOCRINE VS LUMINAL | |
| VERRECCHIA RESPONSE TO TGFB1 C6 | DSP, IGFBP4, NEO1, EPHB4 |
| FARMER BREAST CANCER CLUSTER 4 | |
| CORUM PEX26-PEX6-PEX1 COMPLEX | PEX6, PEX26, PEX1 |