| Gene Set | Leading Edge Genes |
|---|
| MITSIADES RESPONSE TO APLIDIN DN | SEPT9, SYK, RRM2, NCAPD2, RSRC1, SHCBP1, CDC42BPA, TOP2A, CENPF, EPRS, HCFC1, GMPS, RAP2A, MCM5, WEE1, KIAA0100, TIPIN, DSP, NUP188, NUP205, RNASEN, CSNK2A1 /// CSNK2A1P, SKP2, GNB1, CHAF1A, CHD4, POLD3, HELLS, AP3D1, SNRPA, TPX2, TBL1X, EIF4B, NARG1, BIRC5 |
| WHITEFORD PEDIATRIC CANCER MARKERS | RRM2, H2AFX, TOP2A, DNMT1, CENPF, TWIST1, CKS1B, CDK6, CCNB2, EIF4EBP1, MCM5, NUDT1, TPX2, POLE2, MFN2, CCNT1, BIRC5 |
| SOTIRIOU BREAST CANCER GRADE 1 VS 3 UP | BOLA2 /// BOLA2B, ESPL1, ORMDL2, TIMELESS, RRM2, SPAG5, SNRPF, EXO1, OIP5, TOP2A, PSMA7, COX7B, CENPF, CCNB2, FEN1, GMPS, NUDT1, TPX2, CCT5, PFDN6, NUP93, DNAJC9, MCM6, HIST1H4B, H2AFV, BIRC5 |
| REACTOME INSULIN SYNTHESIS AND SECRETION | RPL10, RPL27, RPS11, RPL24, RPL38, RPN2, RPS6, RPL23, RPS16, RPLP0, RPL18, RPL12, RPS9, UBA52, RPL14, SSR4, RPS8, STXBP1, RPL13A, RPL17, RPL10A, RPL41, RPL3, RPS15A, RPL35, RPS18, PCSK1, RPL23A, SSR3, RPS10, RPS23, RPS19, FAU, RPS7, RPL19, RPS29, RPS13, RAB27A, RPL15, SEC61A1, RPL31, NKX2-2, RPL7, RPS27, RPS15, PAX6, SRPRB |
| ODONNELL TARGETS OF MYC AND TFRC DN | ACACA, CKS1B, CHAF1A, CDC6, HELLS, POLE2, TOP2A, CENPF, BIRC5 |
| LUI THYROID CANCER CLUSTER 3 | PSMD8, UBE2E3, SARS, FBL, RPL18, RPL10A, RPL17, CLDN7 |
| REACTOME INFLUENZA LIFE CYCLE | RPL10, RPL27, RPS11, RPL24, RPL38, RPS6, RPLP0, RPS16, RPL23, RPL18, RPL12, RPS9, POLR2G, UBA52, RPL14, RPS8, NUP88, NUP188, RPL13A, NUP205, RPL10A, RPL17, RPL41, RPL3, RPS15A, RPL35, RPS18, RPL23A, RPLP1, NUP210, RPS10, RPS23, RPS19, KPNB1, FAU, RPS7, RPS29, RPS13, RPL19, NUP93, RPL15, RPL31, RPS27, NUP62, RPL7, RPS15, HSPA1A |
| MONTERO THYROID CANCER POOR SURVIVAL UP | CCNB2, RRM2, DIAPH3, BIRC5, CENPA |
| KUMAMOTO RESPONSE TO NUTLIN 3A DN | CDKN3, KIFC1, CENPF, SPAG5 |
| CORUM 40S RIBOSOMAL SUBUNIT CYTOPLASMIC | RPS15A, RPS11, RPS18, RPS17, RPS3A, RPS6, RPS10, RPS14, RPS16, RPS21, RPS9, RPS23, RPS19, FAU, RPS7, RPS13, RPS29, RPS8, RPS27, RPS24, RPS15 |
| REACTOME REGULATION OF BETA CELL DEVELOPMENT | RPL10, RPL27, RPS11, RPL24, RPL38, RPS6, RPL23, RPS16, RPLP0, RPL18, RPL12, RPS9, UBA52, RPL14, RPS8, RPL13A, RPL17, RPL10A, RPL41, RPL3, RPS15A, RPL35, RPS18, RPL23A, RPS10, NKX6-1, RPS23, RPS19, FAU, RPS7, RPL19, RPS29, RPS13, RPL15, RPL31, NKX2-2, RPL7, RPS24, RPS27, RPS15, PAX6 |
| CHNG MULTIPLE MYELOMA HYPERPLOID UP | RPL35, EEF1B2, RPL24, RPLP1, RPS17, RPS6, RPS16, RPL18, RPS9, RPS23, RPS19, UBA52, RPS13, RPL14, RPL15, RPL28, FBL, RPL13A, RPS15 |
| NCI RECRUITMENT OF REPAIR AND SIGNALING PROTEINS TO DOUBLE STRAND BREAKS | ATM, TP53BP1, H2AFX |
| REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | RPL10, RPL27, RPS11, RPL24, RPL38, RPS3A, RPS6, RPL23, RPS16, RPLP0, RPL18, RPL12, RPS9, POLR2G, UBA52, RPL14, RPS8, RPL13A, RPL17, RPL10A, RPL41, RPL3, RPS15A, RPL35, RPS18, RPL23A, RPS10, RPS23, RPS19, FAU, RPS7, RPL19, RPS29, RPS13, RPL28, RPL15, RPL31, RPL7, RPS24, RPS27, RPS15 |
| MODY HIPPOCAMPUS PRENATAL | RPS18, SFPQ, RPL23A, RPL19, RPS8, H2AFV, H2AFX, RPS27, RPL12, TOP2A |
| REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | RPL10, RPL27, RPS11, RPL24, RPL38, RPS3A, RPS6, RPL23, RPS16, RPLP0, RPL18, RPL12, RPS9, UBA52, RPL14, RPS8, RPL13A, RPL17, RPL10A, RPL41, RPL3, RPS15A, RPL35, RPS18, RPL23A, RPS10, NKX6-1, RPS23, RPS19, FAU, RPS7, RPL19, RPS29, RPS13, RPL28, RPL15, RPL31, NKX2-2, RPL7, RPS24, RPS27, RPS15, PAX6 |
| CORUM 60S RIBOSOMAL SUBUNIT CYTOPLASMIC | RPL10, RPL35, RPL27, RPL24, RPL23A, RPL38, RPLP1, RPL23, RPLP0, RPL18, RPL12, RPL19, RPL14, RPL15, RPL13A, RPL31, RPL7, RPL10A, RPL17, RPL41, RPL3 |
| REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | RPS15A, RPS11, RPS18, RPS3A, RPS6, RPS10, EIF2S2, RPS16, RPS9, RPS23, FAU, RPS7, RPS13, RPS29, RPS8, RPS24, RPS27, RPS15 |
| NCI REGULATION OF THE FANCONI ANEMIA PATHWAY | UBB, UBA52, ZBTB32 |
| NCI FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | RPS15A, RPS11, RPS18, RPS3A, RPS6, RPS10, EIF2S2, RPS16, RPS9, RPS23, FAU, RPS7, RPS13, RPS29, RPS8, RPS24, RPS27, RPS15 |