| Gene Set | Leading Edge Genes |
|---|
| DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP | CHPT1, RPN2, TARS, PTPLA, GOT2, TXNL1, PCBD1, ICT1, ADH5, NDUFA8, CREG1, POLD2, ABCD3, PDHA1, DUSP12, AZIN1, IDE, STRAP, GMCL1, SPAG7, COPS4, NBN, ETFA, COPB2, ACOT1 /// ACOT2, PDAP1, CAD, AGL, PPM1A, SLC39A8, MTHFD1, LMAN1, PSMD1, GLUD1, HEBP1, DDB1, ALG3, ETNK1, ARF4, CYCS, LIN7C, FKBP3, NDUFB6, GLO1, PRDX3, ATP5B, HSD17B4, XPOT, PHB2, NMT2, MRPS35, STK11, C1QBP, SLC25A11, ALAD, NCBP2, EIF4E, ARCN1, TAF6, CTNNBL1, POLR2E, UQCRC1, HMG20B, RPS27L, DPAGT1, MTX2, GNAI3, ATP5J2, SSBP1, NIPSNAP1, CAPN7, NDUFAB1, AK2, BAG4, ALDH1A1, PDHB, DLD, ACSL1, COPS2, TOMM22, NIT2, MTCH2, ATIC, MAP2K2, HBS1L, MRPS15, EIF2B1, CPOX, UBE2E3, HDAC2, IMPA1, MRPS31, UROS, FASN, DARS, PRDX6, MYCBP, NME1, RBBP4, ABCE1, COPS5, DAD1, PRDX4, ACY1, ELAVL1, YES1, CCT3, MRPL49, MRPS30, CSNK2A1, PSMA3, CYC1, FTSJ2, ATP5O, BLMH, GSPT1, PEBP1, UGP2, FDPS, SORD, COPS3, PMPCB, CNIH, SUCLA2, PPP2R5C, IDH3B, MAPK1, NDUFV2, ABCB6, PAPSS1, CUL5, WHSC2, SLC16A1, ALDH9A1, RANBP9, NQO2, SDCCAG3, IMMT, OGDH, HSD17B12, PXMP3, GCLC, PCCB, PUS1, PTOV1, PEX1, HADHA, CYP51A1, XRCC5, FADS2, PPM1B, CFDP1, CLPX, HIBCH, SDHD, EIF5, TFG, PKP4, SNX3, NDUFA5, FXN, TM2D1, ETFDH, MCCC2, STOML2, FKBP4, COMT, PRKAG1, SEC31A, TST, NDUFB5, MIF, ORC5L, GAS2, PCTP, RREB1, MDH1, STAU2, PDCD2, SLC29A1, LSS, GCDH, EIF4G1, ST13, ITM2A, PDHX, SLC27A2, SEP15, UBE4A, PGRMC2, GBE1, HMBS, SNRPN /// SNURF, CCNH, LASS2, RANGAP1, ACO2, RSC1A1, CTH, PSMD2, PCMT1, MSH6, DCUN1D1, AQP3, PSMD12, SUCLG1, CBARA1, ADSS, CDK8, HMGCS1, QDPR, GTF2H4 |
| BLALOCK ALZHEIMERS DISEASE DN | GSTA4, HSPD1, ASPH, RPN2, SLC30A9, GOT2, ADH5, NDUFA8, NPAS2, HYOU1, HSPA5, NFYC, PDHA1, AZIN1, NDUFS2, PREP, RNF11, DDT, CCT4, COPS4, ATP5F1, NDUFB11, ETFA, UBE2A, ACOT1 /// ACOT2, COX5A, TTRAP, SLC25A3, DLAT, MTHFD1, MCCC1, PPIA, VDAC1, CSE1L, PSMD1, PPP1R2, MRPS28, GLUD1, KPNB1, MRPL18, PTEN, NDUFS4, ARF4, PSMD6, CYCS, UQCRQ, FKBP3, GLO1, PRDX3, DCTN2, COX8A, COX7C, ATP5B, PSME3, MRPS10, ACTR1B, IARS, DHCR7, WFDC1, NDUFB8, SLC25A11, NCBP2, RPE, ARCN1, MECR, GADD45GIP1, UQCRC1, AES, ATP5A1, PDIA6, PPA1, TFRC, MTX2, ELOVL2, ATP5J2, MFN1, TMEM14A, SSBP1, NIPSNAP1, USP10, NDUFAB1, SAMM50, MET, COX6C, NDUFS3, SRP72, TUBB2A, ABAT, PDHB, DLD, COPS7A, UAP1, SDHB, LDOC1, HPRT1, ERGIC2, THOC5, NIT2, MTCH2, MGLL, ATIC, NF2, MRPS15, EIF2B1, HIGD1A, GORASP2, CHMP2A, CS, UBE2E3, UROS, ECH1, DARS, ATP5L, BAT3, DYNLT3, ARPC5L, NME1, ABCE1, COPS5, DNAJB9, PRDX4, CCT3, SLC35A1, HSPE1, CSNK2A1, LDHA, CYC1, RDH11, COX11, MRPL20, ABHD6, AHSA1, ATP5O, PSMB5, F8, UGP2, GUK1, COX6B1, PMPCB, METTL5, SUCLA2, PTRH2, GRPEL1, PPP2R5C, IDH3B, CNTNAP2, MAPK1, NDUFV2, NUDT11, CNKSR2, PAPSS1, PEX7, ZNHIT3, COMMD3, MRPL15, RANBP9, NDUFB4, TMEM147, PDCD5, PTS, HSD17B12, TMEM126B, DNAJA1, PCCB, PEX1, CCT5, SMYD2, WDR12, NDUFA4, PEX19, SDHD, PCTK1, EIF5, PJA1, SC5DL, SNX3, UQCR, NDUFA5, UQCRH, TM2D1, SDHA, MCCC2, SEC31A, NDUFB5, ORC5L, DDX47, MKKS, MDH1, METAP1, PDCD2, TRIM37, MRP63, MTERFD1, PDHX, SEP15, MARS, UQCRC2, NDUFB2, MRPL16, HCCS, MRPL13, BET1, EBP, MRPL22, LRPPRC, ATP5C1, PFDN2, UBC, SNRPN /// SNURF, CCNH, HSP90AA1, SLC35B1, ACO2, MAOA, NDUFB3, ARNT2, MTMR4, PCMT1, NECAP1, TSNAX, PSMD12, CBARA1, TUBB2C, TM2D3, PSMB3, OPA1 |
| REACTOME DIABETES PATHWAYS | NDUFV1, RPN2, SLC2A2, CYC1, ENO1, SDHC, NDUFA8, NDUFB7, ATP5O, NDUFS6, HSPA5, COX6B1, PDHA1, SSR2, NDUFS2, SUCLA2, ATP5F1, SUCLG2, NDUFB11, ETFA, NDUFA12, IDH3B, BCHE, SLC30A6, NDUFC1, NDUFB10, COX5A, NDUFV2, SPCS3, NDUFS7, DLAT, PKLR, NDUFA10, NDUFB4, OGDH, NDUFA9, SRP9, CYCS, UQCRQ, NDUFA4, IGFBP5, NDUFB6, COX8A, ATP5B, COX7C, SDHD, IDH2, ATP5I, SEC61B, NDUFA5, UQCRH, NDUFB8, SDHA, NDUFB5, UQCRFS1, NDUFS1, GLP1R, UQCRC1, NDUFA6, ATP5A1, DLST, PRKAR2A, EXOC3, PDIA6, ATP5G1, ATP5J2, SSR4, PDHX, NDUFAB1, NDUFB2, UQCRC2, COX6C, NDUFS3, PDHB, DLD, ERN1, ATP5C1, SDHB, ATP5D, SSR3, IGFALS, ACO2, NDUFB9, DNAJB11, NDUFB3, SUCLG1, CS, ATP5L |
| KRIGE RESPONSE TO TOSEDOSTAT 24HR DN | HDGF, HSPD1, CHCHD7, CLPB, NTHL1, CFL2, MRPL12, GOT2, SDHC, RG9MTD1, POLD2, ABCD3, SUPV3L1, FABP5, SPRYD4, PMPCA, SLC25A10, MRPL14, NDUFB10, PDAP1, COX5A, COQ3, GNPNAT1, NFE2L3, MRPL41, VDAC1, MRPL4, MRPL36, PEX5, CYB5A, ALG3, TOP1MT, MON1A, B3GALNT2, ABCB10, MRPL21, STK11, DHCR7, MPP6, IFRD2, C1QBP, NUDT7, DNAJC11, BDH1, NCBP2, EIF4E, DCXR, SESN3, ATP5J2, BCCIP, NDUFAB1, NDUFS3, TTLL12, UAP1, ATP5D, PCOLCE2, MRPS12, MTCH2, MGLL, SCFD2, POLR3G, AK3L1, SNRPN, HDAC2, GCAT, FASN, METTL8, STIP1, ENDOG, SPR, VKORC1L1, MAP2K3, NME1, TMEM109, ABCE1, MMACHC, PRDX4, ACY1, CCT3, AURKAIP1, SFXN1, HSPE1, LDHA, COX11, TIMM13, RHOT2, NDUFB7, GSPT1, PEBP1, SORD, GPD1L, XRCC6BP1, GRPEL1, IDH3B, TIMM8B, TBL3, MRPS25, RNF126, SRM, SLC16A1, GGA2, TMEM70, TMEM147, PDCD5, B3GAT3, DNAJA1, INSIG1, SLC25A19, CFDP1, TIMM50, PKP4, GFM1, ATP5I, MRPS34, FXN, NCLN, FKBP4, FTSJ1, LAS1L, MIF, GLRX5, SLC29A1, BOLA3, ATP5G1, KTI12, NR2F2, MRP63, ITM2A, MRPL16, EBP, LRPPRC, EXOSC7, HSP90AA1, RANGAP1, RSC1A1, SLC25A30, HES6, MSH6, WDR74, QDPR, DEPDC6 |
| STEIN ESRRA TARGETS | MMACHC, ECSIT, ACY1, NDUFV1, C16ORF61, MRPS30, GOT2, BRP44, COQ9, NDUFA8, ATP5O, SUPV3L1, GSTM1, UGP2, PDHA1, DSG2, NDUFS2, PAFAH2, GMCL1, GRPEL1, SUCLA2, IDH3B, COX5A, COQ3, SLC25A3, NDUFS7, SLC39A8, FZD2, DLAT, MOSC2, MRPS11, MRPL4, SLC16A1, EHHADH, RFXANK, MRPL15, FDX1, NQO2, IMMT, DCI, OGDH, NDUFA9, CYCS, FDXR, CHCHD3, TIMM50, BMP7, SDHD, STARD7, MLYCD, MRPL2, ALDH3A2, TEX2, DNAJC11, SDHA, NDUFB5, GSTM4, UQCRFS1, NDUFS1, MRPS22, CLDN1, ABLIM1, MECR, UQCRC1, MDH1, WWC1, PPIF, ATP5G1, CAV2, NR2F2, PDHX, UQCRC2, MRPL34, HCCS, NDUFS3, QRSL1, MFN2, EBP, FZD10, DLD, GSTK1, ATP5C1, SDHB, MRPS12, MRPL35, ACO2, SEC14L2, GATAD1, FBXL15, MSH6, HIGD1A, HEXIM1, SUCLG1, CS, IMPA1, AFG3L2, SLC10A2, ENDOG, OPA1, ATP5L |
| KRIGE RESPONSE TO TOSEDOSTAT 6HR DN | MAP2K3, HDGF, MMACHC, ABCE1, TMEM109, HSPD1, CHCHD7, PRDX4, CCT3, NTHL1, CFL2, AURKAIP1, MRPL12, GOT2, SFXN1, LDHA, COX11, SDHC, TIMM13, NDUFB7, RHOT2, RG9MTD1, POLD2, ABCD3, FABP5, PEBP1, SPRYD4, GPD1L, SORD, XRCC6BP1, GRPEL1, SLC25A10, IDH3B, MRPL14, NDUFC1, TIMM8B, PDAP1, NDUFB10, COQ3, TBL3, GNPNAT1, NFE2L3, MRPL41, RNF126, VDAC1, MRPL4, SRM, GGA2, SLC16A1, TMEM70, PDCD5, TMEM147, MRPL36, PEX5, CYB5A, DNAJA1, B3GAT3, ALG3, INSIG1, TOP1MT, SLC25A19, SMYD2, MON1A, B3GALNT2, CFDP1, MRPL21, STK11, DHCR7, GFM1, MPP6, ATP5I, MRPS34, C1QBP, NUDT7, DNAJC11, FKBP4, NCBP2, LAS1L, EIF4E, MIF, GLRX5, DCXR, ATP5G1, BOLA3, SESN3, ATP5J2, MRP63, NR2F2, BCCIP, MRPL16, NDUFS3, TTLL12, LRPPRC, UAP1, EXOSC7, MRPS12, RANGAP1, MTCH2, MGLL, SCFD2, RSC1A1, SLC25A30, MSH6, HES6, WDR74, POLR3G, SNRPN, HDAC2, GCAT, FASN, QDPR, STIP1, METTL8, SPR, ENDOG, VKORC1L1 |
| KAAB HEART ATRIUM VS VENTRICLE DN | C1QBP, SDHA, MCCC2, ELAC2, BDH1, ASS1, CSRP2, GOT2, NDUFS1, UQCRFS1, CYC1, COQ9, ADH5, ABLIM1, UQCRC1, ATP5A1, TSFM, NDUFS6, METAP1, CDK2AP2, MRPS18B, PDHX, NDUFS2, COPS3, GBE1, NDUFS3, PPP2R5C, ACADVL, IDH3B, GPT, COX5A, SLC25A3, NDUFV2, DLD, ATP5C1, SDHB, NDUFS7, VDAC1, HRAS, DCI, OGDH, CYB5A, AZGP1, NDUFA9, IPO13, AK3L1, HADHA, UQCRQ, SMYD2, MAOB, PRDX3, ACADS, COX8A, GCAT, ECH1, AFG3L2, SDHD, IDH2, HIST2H2BE, OPA1, STARD7 |
| ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE UP | CHPT1, NUDCD2, SH3D19, SDF2L1, BRP44, TIPRL, ICT1, HSPA14, SDHC, NDUFA8, BOLA1, HYOU1, GMPS, YIF1B, DUSP12, COPB2, NOL7, IRAK1, DTYMK, SCAMP3, PPP1R2, TATDN1, MRPL36, UBLCP1, MRPL18, MRPS17, TAF12, PSMD6, GNMT, NDUFB6, SEC61G, PHPT1, PSME3, IDI1, XPOT, P4HA2, MRPL48, XRCC6, IFRD2, SEC61B, ELOVL6, C1QBP, SLC33A1, NCBP2, ABHD5, MID1IP1, APEX1, FOXQ1, CDK2AP2, TOM1L1, PDIA6, ACP1, TFRC, PPA1, HDDC3, TINF2, TMEM14A, CPVL, PSEN2, NAGS, ALG14, REXO2, LYAR, RANBP6, VAMP5, HPRT1, PCOLCE2, DVL3, RBBP7, PIR, MAP2K2, USP34, EIF2B1, HIGD1A, CCDC91, DRG1, SPCS1, MRPS18C, F5, TBL2, PSMB4, SFXN2, FKBP11, MRPL9, CSTF2, DAD1, IARS2, DYNLRB1, ZCCHC17, TMEM85, ACTL6A, PSMB5, MRPS18B, PIGY, SSR2, XRCC6BP1, CNN3, CNIH, NDUFA12, PAPSS1, COMMD3, WDR8, PDCD5, TMEM147, AQP11, RPL36AL, NUDT1, IDH1, PEX19, YARS2, HIST2H2BE, TFG, TRIP4, COPE, AHCY, TM2D1, DHX29, CHMP5, OBFC2B, NDUFB5, UFC1, METAP1, CHCHD1, MARS, GBE1, CRY1, HAX1, STT3B, SURF1, SLC35B1, SEC14L2, RPA3, UFM1, DNAJB11, NDUFB3, MEA1, PSMD2, MSH6, DNAJC19, TSNAX, FADD, CCDC51, TUBB2C, DARS2, GTF2H4, KDELR2, DEPDC6 |
| ACEVEDO NORMAL TISSUE ADJACENT TO LIVER TUMOR DN | MRPS18A, REEP6, NDUFB8, AHCY, DHRS1, TM7SF2, FKBP4, GOT2, SFXN1, PGM2, PSMA3, KHDRBS3, NSDHL, ABHD6, ATP5O, RXRA, HSPA5, HAGH, CDK2AP2, VPS26B, BOK, FEM1A, CYB5B, PAFAH2, F10, PGRMC2, ARMC6, MRPL22, ADH4, SDHB, LDLR, AGMAT, TGDS, SLC35B1, KPNA1, MRPS11, PPM1F, IGFALS, OTC, PSMB7, RETSAT, STARD10, MAOA, GLUD1, DNAJB11, MEA1, LSMD1, ATF5, DNAJA1, SH3BGRL2, RPL36AL, AARS, CLPP, GNMT, ZFPM1, HMGCS1, MRPL53, GPD1, MRPS31, FASN, STK11, ENDOG |
| REACTOME METABOLISM OF AMINO ACIDS | DLD, AGMAT, SRM, MCCC2, OTC, ASS1, GOT2, DBT, ALDH9A1, GLUD1, PCBD1, GAMT, DLST, BBOX1, GSTZ1, GCDH, AZIN1, HIBCH, SLC38A3, QDPR |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 13 | 2010107E04RIK, 1110020P15RIK, UQCR, MRPS18A, NDUFA5, NDUFB8, CSRP2, NCBP2, PIGX, TMEM93, USMG5, ATP5O, PQBP1, CYB5B, GUK1, 1810046J19RIK, NDUFS2, NDUFAB1, PPIB, PMPCB, MRPL45, UQCRC2, ATP5F1, MRPL13, PPP2R5C, NDUFB11, EBP, TIMM8B, NDUFC1, NDUFA13, 2410015M20RIK, 1810020G14RIK, ATP5D, PEX7, PARK7, MRPL35, PDCD5, GSTM5, TSEN34, MRPL18, NDUFA9, PCCB, FKBP3, POLR3K, ECH1, 0610007P14RIK |
| REACTOME BIOLOGICAL OXIDATIONS | ALDH1A1, GCLC, ADH4, GSTA3, SULT1B1, GLYAT, AHCY, SULT1C2, CYP2U1, GSTP1, MAOB, COMT, TPMT, GSTM4, ADH1A, GSTM5 |
| REACTOME PYRUVATE METABOLISM AND TCA CYCLE | DLD, PDHB, SDHB, DLAT, SLC16A1, ACO2, LDHA, SDHC, OGDH, DLST, SUCLG1, CS, PDHX, SUCLA2, SDHD, IDH3B |
| WELCSH BRCA1 TARGETS 1 DN | DDX11, SCAP, BOP1, FKBP4, NSDHL, AGPAT2, HSP90B1, EMG1, RXRA, SLC29A1, POLG, SSBP1, NDRG1, BYSL, DHCR24, EIF4G1, MAP2K5, DDT, PMPCA, LMNB2, CAD, CDC37, MTHFD1, HDLBP, VDAC1, MRPS12, SRM, PPM1F, PSMD1, ATIC, ALG3, FDFT1, XRCC5, FASN, U2AF1, SLC39A7 |
| REACTOME PHASE II CONJUGATION | GSTA4, GCLC, GSTM1, GSTA3, SULT1B1, UGDH, GLYAT, AHCY, SULT1C2, GSTP1, COMT, TPMT, GSTM4, GSTM5 |
| KEGG TYROSINE METABOLISM | HEMK1, GSTZ1, ADH4, LCMT2, DDC, MAOB, GOT2, COMT, ADH1A, MIF, MAOA, ADH5, LCMT1 |
| MCBRYAN PUBERTAL BREAST 4 5WK DN | MLX, RBBP4, TMEM109, REEP6, SFXN1, CSNK2A1, MLXIPL, 9530058B02RIK, FABP5, ERAL1, EIF4G1, NFIC, 4933439F18RIK, GYK, NID2, UBE4A, HCCS, GPAM, SLC25A10, ACADVL, IDH3B, BCHE, DLAT, ATP5D, ACSL1, BPNT1, IGFALS, ACO2, MTCH2, EHHADH, COQ5, DBT, IMMT, DCI, PPARGC1B, SUCLG1, ECH1, GPD1, 2810405K02RIK |
| RODWELL AGING KIDNEY NO BLOOD DN | LRPPRC, GSTA4, UAP1, DLAT, PRKAA2, MTO1, RHOBTB3, GOT2, DBT, GSTM4, NDUFS1, CYB5A, ADH5, CTH, PET112L, ATP5A1, SRP9, CYCS, PEBP1, SULT1C2, DSG2, PRDX3, COX8A, AK2, COX7C, COX6C, BMP7, ISOC1 |
| KEGG ARGININE AND PROLINE METABOLISM | GAMT, AGMAT, PYCRL, ALDH3A2, ACY1, SRM, MAOB, OTC, ASS1, GOT2, ALDH9A1, GLUD1 |
| KEGG GLUTATHIONE METABOLISM | GSTA4, GSTZ1, GCLC, GSTK1, GSTM1, GSTA3, IDH1, SRM, GSTP1, GSTM4, GSTM5 |
| GOLDRATH HOMEOSTATIC PROLIFERATION | HDGF, MRPL9, NME1, GNPNAT1, MRPS25, ATP5D, ALDH3A2, RAB18, NUDCD2, DUSP19, SFXN1, HSPE1, BRP44, IPP, SDHC, NDUFB3, PPA1, AU021838, LIN7C, BYSL, YIPF5, RNF11, NDUFAB1, 2310028O11RIK, GYK, GALK1, NDUFB2, QDPR, NDUFC1, PDAP1 |
| RAMALHO STEMNESS UP | SEC23A, FKBP11, GSTA4, ELOVL6, MRPL17, GFER, YES1, IARS2, SH3D19, PIGX, LAS1L, GAS2, ARCN1, TXNL1, UTP20, PDCD2, TOM1L1, PPA1, BYSL, MTERFD1, USP10, NDUFAB1, PAFAH2, MRPL45, MRPL34, RABGGTB, RYK, COPS4, SUCLG2, LSM2, LIG3, COPS7A, CAD, RAB18, PEX7, DTYMK, PPP1R2, MRPS2, PSMD12, GLO1, RNF4, XRCC5, GCAT, MRPS10, MRPS31, XPOT, ZFP213, IARS |
| CORUM RESPIRATORY CHAIN COMPLEX I BETA SUBUNIT MITOCHONDRIAL | NDUFB3, NDUFB7, NDUFB8, NDUFB6, NDUFA4, NDUFAB1, NDUFB5, NDUFB9, NDUFB2, NDUFB4, NDUFB11, NDUFB10 |
| REACTOME TRNA AMINOACYLATION | AARS, LARS2, IARS2, TARS, NARS2, MARS, DARS2, YARS2, IARS, DARS |
| REACTOME CITRIC ACID CYCLE | DLST, DLD, SDHB, SDHA, SUCLG1, CS, ACO2, IDH2, SUCLA2, SDHD, SUCLG2, IDH3B, OGDH, SDHC |
| KEGG GLYCOLYSIS GLUCONEOGENESIS | DLD, PDHB, ADH4, ACSS2, ALDH3A2, DLAT, PKLR, PGM2, ALDH9A1, ADH1A, ENO1, ADH5 |
| CORUM RESPIRATORY CHAIN COMPLEX I LAMBDA SUBUNIT MITOCHONDRIAL | NDUFA13, NDUFS6, NDUFV2, NDUFS7, NDUFA5, NDUFV1, NDUFS2, NDUFS3, NDUFS1, NDUFA12 |
| KEGG PYRUVATE METABOLISM | MDH1, GRHPR, DLD, PDHB, HAGH, ACOT12, ACSS2, ALDH3A2, DLAT, GLO1, PKLR, ALDH9A1 |
| CORUM RESPIRATORY CHAIN COMPLEX I INCOMPLETE INTERMEDIATE MITOCHONDRIAL | NDUFA9, NDUFS6, NDUFV2, NDUFS7, NDUFB8, NDUFV1, NDUFS2, NDUFA10, NDUFS1 |
| KEGG ALANINE ASPARTATE AND GLUTAMATE METABOLISM | GPT, NIT2, ASS1, ADSS, ASPA, GOT2, ACY3, AGXT, GLUD1, ABAT |
| NCI CITRIC ACID CYCLE TCA CYCLE | SDHB, SDHA, SUCLG1, CS, IDH3G, ACO2, SDHD, SUCLA2, SUCLG2, SDHC, IDH3B |
| ALONSO METASTASIS UP | GSTA4, DAD1, RAN, ENO1, CYC1, MRPS22, NME2, MDH1, CHCHD1, COX6B1, DUSP12, DSG2, BCCIP, NDUFAB1, IDE, GABARAP, NDUFB11, PPP2R5C, SLC30A6, MRPL37, AKT1S1, VDAC1, MRPL15, NDUFB3, AK3L1, CCT5, GLO1, XRCC5, POLR3K, COX8A, BZW1, SDHD, LHFPL2, EIF5 |
| KEGG CYSTEINE AND METHIONINE METABOLISM | SRM, CTH, BHMT, GOT2, CBS, LDHA, AHCY, TAT |
| KEGG HISTIDINE METABOLISM | HEMK1, ALDH3A2, DDC, MAOB, ASPA, FTCD, ACY3, ALDH9A1, LCMT1 |
| MOOTHA TCA | SDHB, SDHA, SUCLG1, CS, ACO2, SUCLA2, SDHD, IDH2, SDHC, OGDH, IDH3B |
| REACTOME STEROID METABOLISM | SC5DL, ACOT8, TM7SF2, SLC10A1, ABCB11, CYP8B1, MVK, NSDHL, HSD17B7, LSS, DHCR24, SLC27A2, STARD4, CYP51A1, FDFT1, ACOX2, IDI1, HSD17B4, HMGCS1, SLC10A2, HSD3B7, DHCR7, EBP |
| LANDIS ERBB2 BREAST PRENEOPLASTIC DN | 1110020P15RIK, CHPT1, MCCC1, NDUFV1, ALDH1A7, HADHB, CPT2, ALAD, ACAA1B, PGM2, ACAA2, ABHD5, GSTZ1, PDHA1, NDUFAB1, GPD2, GBE1, GPAM |
| REACTOME GLUTATHIONE CONJUGATION | GSTP1, GSTA4, GSTM4, GCLC, GSTA3, GSTM1, GSTM5 |
| KEGG SELENOAMINO ACID METABOLISM | CTH, HEMK1, MARS, PAPSS2, CBS, LCMT2, PAPSS1, AHCY, LCMT1 |
| PELLICCIOTTA HDAC IN ANTIGEN PRESENTATION UP | SAR1B, SAR1A, COPE, GOPC, PSMD1, PSMB7, SEC22B, PSMC4, TRAPPC1, PSMD4, WFS1, COPZ1, HSP90B1, PSMD2, GOSR2, TRAPPC3, HSPA5, PSMD6, PSMD3, COPB1, TMED7, PDIA4, YIPF5, PSMB3, TRAPPC4, COPB2, BCAP31, COPG, KDELR2, PSMB4 |
| KEGG BETA ALANINE METABOLISM | SRM, EHHADH, MLYCD, HIBCH, ALDH9A1, ALDH3A2, HADHA, ABAT |
| RODWELL AGING KIDNEY DN | LRPPRC, PRKAA2, DLAT, MTO1, RHOBTB3, GOT2, DBT, NDUFS1, ADH5, ATP5A1, CYCS, PEBP1, SULT1C2, AK2, COX7C, BMP7, ISOC1 |
| BIOCARTA ETC PATHWAY | UQCRC1, ATP5A1, GPD2, CYCS, SDHB, SDHD, SDHC, SDHA |
| HU ANGIOGENESIS DN | ATP5O, MDH1, SOD1, GMPS, HMGN1, GCDH, SMYD2, NDUFB6, ITM2A, RPA3, DARS |
| REACTOME CHOLESTEROL BIOSYNTHESIS | SC5DL, LSS, DHCR24, TM7SF2, CYP51A1, FDFT1, IDI1, HMGCS1, MVK, DHCR7, NSDHL |
| NCI OXIDATIVE DECARBOXYLATION OF PYRUVATE TO ACETYL COA BY PYRUVATE DEHYDROGENASE | PDHX, DLD, PDHB, DLAT, PDHA1 |
| KEGG PHENYLALANINE METABOLISM | DDC, PRDX6, MAOB, GOT2 |
| PENG RAPAMYCIN RESPONSE DN | PSMD5, TMEM109, TGDS, MRPS11, SRM, CSE1L, MRPL12, HSPE1, ATF5, NDUFA9, HYOU1, ATP5G1, JTB, CHUK, RABGGTB, FASN, HCCS, COPB2 |
| KEGG PENTOSE AND GLUCURONATE INTERCONVERSIONS | XYLB, DHDH, UGT2A3, DCXR, RPE, UGDH |
| REACTOME VITAMIN B5 (PANTOTHENATE) METABOLISM | COASY, PPCS, PANK3, FASN, SLC25A16, PANK1 |
| CORUM F1F0-ATP SYNTHASE EC 3.6.3.14 MITOCHONDRIAL | ATP5O, ATP5A1, ATP5I, ATP5C1, ATP5D, ATP5G1, ATP5J2, ATP5J, ATP5E, ATP5H, ATP5B, ATP5F1 |
| BARIS THYROID CANCER UP | CYCS, CYC1, STIP1 |
| KEGG TERPENOID BACKBONE BIOSYNTHESIS | FDPS, IDI1, PDSS2, HMGCS1, DHDDS, MVK |
| REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | ATP5O, ATP5A1, ATP5I, ATP5C1, ATP5D, ATP5G1, ATP5J2, ATP5J, ATP5E, ATP5H, ATP5B, ATP5F1 |
| NCI FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | ATP5O, ATP5A1, ATP5I, ATP5C1, ATP5D, ATP5G1, ATP5J2, ATP5J, ATP5E, ATP5H, ATP5B, ATP5F1 |
| CORUM TERF2-RAP1 COMPLEX | |
| KIM MYC AMPLIFICATION TARGETS UP | |
| BIOCARTA KREB PATHWAY | |
| REACTOME RNA POL II CTD PHOSPHORYLATION AND INTERACTION WITH CE | |
| ROME INSULIN TARGETS IN MUSCLE UP | PRDX6, TMEM109, COPS6, COPE, MRPS16, SLC35B1, CCT6A, CFL2, PPP2R5B, TMEM70, ARCN1, TMEM93, DCUN1D1, HIGD1A, CHCHD1, COPS3, HCCS, MLLT1, UBQLN1, PSMB4 |
| KEGG ASCORBATE AND ALDARATE METABOLISM | |
| CORUM DDB2 COMPLEX | |
| BANDRES RESPONSE TO CARMUSTIN WITHOUT MGMT 48HR DN | |
| KEGG GLYCOSYLPHOSPHATIDYLINOSITOL GPI ANCHOR BIOSYNTHESIS | |
| CORUM ECSIT COMPLEX ECSIT NDUFS3 TOM20 | |
| CORUM RESPIRATORY CHAIN COMPLEX I GAMMA SUBUNIT MITOCHONDRIAL | |
| NCI FORMATION OF THE EARLY ELONGATION COMPLEX | WHSC2, POLR2E, NCBP2, GTF2H4, POLR2I, POLR2L, CCNH |
| NCI RNA POLYMERASE II TRANSCRIPTION ELONGATION | POLR2E, POLR2I, POLR2L, TCEB2, CCNH, WHSC2, NCBP2, GTF2H4 |
| WILLIAMS ESR2 TARGETS UP | |
| KEGG GLYOXYLATE AND DICARBOXYLATE METABOLISM | |
| BIOCARTA EIF PATHWAY | |
| COULOUARN TEMPORAL TGFB1 SIGNATURE DN | |
| NCI UREA SYNTHESIS | |
| REACTOME METABOLISM OF VITAMINS AND COFACTORS | |
| IIZUKA LIVER CANCER PROGRESSION G2 G3 UP | |
| KEGG RETINOL METABOLISM | |
| CORUM RESPIRATORY CHAIN COMPLEX I INTERMEDIATE VII/650KD MITOCHONDRIAL | |
| UEDA PERIFERAL CLOCK | |
| WANG RESPONSE TO ANDROGEN UP | |
| KEGG FOLATE BIOSYNTHESIS | |
| KEGG PROTEIN EXPORT | |
| ELLWOOD MYC TARGETS DN | |
| BIOCARTA NUCLEARRS PATHWAY | |
| REACTOME MICRORNA BIOGENESIS | |
| REACTOME MTOR SIGNALLING | |
| HOSHIDA LIVER CANCER SUBCLASS S2 | |
| HOSHIDA LIVER CANCER SURVIVAL DN | |
| WANG RESPONSE TO FORSKOLIN UP | SPCS3, INSIG1, GNAI3, EVI5, NGLY1 |
| KEGG N GLYCAN BIOSYNTHESIS | |
| NCI INSULIN SYNTHESIS AND SECRETION | |
| SCHLOSSER MYC AND SERUM RESPONSE SYNERGY | |
| PETRETTO HEART MASS QTL CIS UP | |
| CORUM COP9 SIGNALOSOME COMPLEX | COPS3, GPS1, COPS5, COPS7A, COPS6, COPS4, COPS2 |
| GRUETZMANN PANCREATIC CANCER DN | |
| REACTOME HIV1 TRANSCRIPTION ELONGATION | POLR2E, POLR2I, POLR2L, TCEB2, CCNH, WHSC2, NCBP2, GTF2H4 |
| CORUM CSA-POLIIA COMPLEX | DDB1, COPS3, GPS1, COPS5, COPS7A, COPS6, COPS4, COPS2 |
| CORUM FRATAXIN COMPLEX | |
| NCI MICRORNA MIRNA BIOGENESIS | |
| SCHLOSSER MYC TARGETS AND SERUM RESPONSE DN | |
| REACTOME ACTIVATION OF CHAPERONES BY IRE1 ALPHA | |
| CORUM RNA POLYMERASE II COMPLEX INCOMPLETE CDK8 COMPLEX CHROMATIN STRUCTURE MODIFYING | |
| KEGG GLYCEROLIPID METABOLISM | |
| NCI RNA POL II CTD PHOSPHORYLATION AND INTERACTION WITH CE | |
| NCI RNA POL II CTD PHOSPHORYLATION AND INTERACTION WITH CE1 | |
| NCI TAT MEDIATED ELONGATION OF THE HIV 1 TRANSCRIPT | |
| LANDIS ERBB2 BREAST TUMORS 324 DN | |
| REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT | WHSC2, POLR2E, NCBP2, POLR2I, POLR2L |
| REACTOME RNA POLYMERASE I III AND MITOCHONDRIAL TRANSCRIPTION | |
| NCI FORMATION OF THE HIV 1 EARLY ELONGATION COMPLEX | WHSC2, POLR2E, NCBP2, GTF2H4, POLR2I, POLR2L, CCNH |
| CORUM CSA COMPLEX | DDB1, COPS3, GPS1, COPS5, COPS7A, COPS6, COPS4, COPS2 |
| KEGG VALINE LEUCINE AND ISOLEUCINE BIOSYNTHESIS | |
| NCI MRNA CAPPING | POLR2E, NCBP2, GTF2H4, POLR2I, POLR2L, CCNH |
| KEGG BIOSYNTHESIS OF UNSATURATED FATTY ACIDS | |
| NCI SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | |
| REACTOME RECYCLING OF BILE ACIDS AND SALTS | |
| KEGG AMINOACYL TRNA BIOSYNTHESIS | |
| NCI HIV 1 TRANSCRIPTION ELONGATION | WHSC2, POLR2E, NCBP2, GTF2H4, POLR2I, POLR2L, CCNH |
| REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX | WHSC2, POLR2E, NCBP2, GTF2H4, POLR2I, POLR2L, CCNH |
| REACTOME COPI MEDIATED TRANSPORT | |
| CORUM RESPIRATORY CHAIN COMPLEX I EARLY INTERMEDIATE NDUFAF1 ASSEMBLY MITOCHONDRIAL | |
| NCI FORMATION OF HIV 1 ELONGATION COMPLEX CONTAINING HIV 1 TAT | POLR2E, POLR2I, POLR2L, TCEB2, CCNH, WHSC2, NCBP2, GTF2H4 |
| HONMA DOCETAXEL RESISTANCE | |
| MORI PLASMA CELL UP | |
| NCI COPI MEDIATED TRANSPORT | |
| REACTOME GENE EXPRESSION | |
| NCI FORMATION OF RNA POL II ELONGATION COMPLEX | POLR2E, POLR2I, POLR2L, TCEB2, CCNH, WHSC2, NCBP2, GTF2H4 |
| NCI REGULATION OF PYRUVATE DEHYDROGENASE COMPLEX PDC | |
| CORUM OLIGOSACCHARYLTRANSFERASE OSTC-III | |
| NCI ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT | WHSC2, POLR2E, NCBP2, POLR2I, POLR2L |
| CORUM CNS-P53 COMPLEX | COPS3, GPS1, COPS5, COPS7A, COPS6, COPS4, COPS2 |
| RICKMAN METASTASIS UP | |
| NCI RECYCLING OF BILE ACIDS AND SALTS | |
| NCI METABOLISM OF FOLATE AND PTERINES | |
| REACTOME TRANSCRIPTION | RRN3, GTF3C5, NFIB, CSTF2, POLR2L, TCEB2, POLR2I, HIST1H2BC, CCNH, WHSC2, POLR2B, NCBP2, TFAM, TAF6, MNAT1, POLR2J, TAF13, POLR2E, POLR2F, TAF12, NFX1, SFRS2, HIST1H4I, NFIC, RNGTT, U2AF1, GTF2H4, CSTF1, GTF3C1, HIST2H2BE |
| NIKOLSKY BREAST CANCER 16P13 AMPLICON | |
| KEGG PANTOTHENATE AND COA BIOSYNTHESIS | |