| Gene Set | Leading Edge Genes |
|---|
| CASORELLI ACUTE PROMYELOCYTIC LEUKEMIA DN | HMGCR, DNM1L, CENPA, AURKB, MRPL12, HDGFRP3, STT3A, TYMS, NCAPH, MCM3, GMPS, MCM5, CLN6, TMEM106C, VCL, DUS4L, DHCR24, KIF22, NDUFS2, CHEK1, TK1, ENOSF1, CEP55, POLD3, CSE1L, NUP155, AP2M1, LPIN1, SC4MOL, ATP6V0D1, CDC20, PAFAH1B3, GLO1, DNAJC9, CSRP1, ZNF544, GPSM2, IDI1, RPA1, HSD17B4, DHCR7, SFRS9, ELOVL6, DNAJC12, ZWINT, CCNB1, RPE, HMGB3, TOP2A, MRPL28, PDK3, ECHDC1, UQCRC1, SLA, FEN1, RECQL4, RNF121, SLC2A10, DCXR, TMEM14A, SNX4, ASPM, TTLL12, PDHB, ARHGAP6, LDLR, SPAG5, ASL, CMAS, ORC1L, DEPDC5, RFC4, HMMR, COIL, CCNA2, SLC16A3, DDX41, RAD54L, CDC25C, FADS1, PCYT2, UROS, STIP1, RFC3, CDKN3, DLEU1, GMPPB, NCAPG, RDH11, SCD, ADIPOR2, GINS1, FTSJ2, CDC6, ACSL3, CIRBP, RAD54B, TMEM97, ATPIF1, MCM2, GGA2, PRMT7, MAD1L1, TRIP13, M6PR, SHQ1, PXMP3, ETFB, ACAT1, PIN4, AARS, PECI, RAP2B, FDFT1, FADS2, KIF15, SMC4, KIF2C, CENPM, BIRC5, KIF20A, SHMT2, NNT, C3ORF37, PLK1, GINS2, SDHA, AURKA, CDC2, KLHDC3, TST, C3ORF14, SF3A3, NAP1L4, CENPF, NSDHL, HOXA9, NUSAP1, STIL, EXOC3, DVL2, ZNF671, NEK9, EBP, SNX5, BUB1B, TPM1, RMND5B, HIRIP3, MAPRE2, ODC1, MEF2C, CCNB2, MCM7, MVD, PRC1, CDC25A, PTGES2 |
| KINSEY TARGETS OF EWSR1 FLII FUSION UP | RCN3, POLA1, MLX, TMPO, AURKB, SLBP, PAX7, NCAPH, MCM3, DUS4L, TKT, RNASEH2A, TK1, MTMR6, NUP155, PPP2R2D, UBE2G1, DTL, GTF2A1, ME2, TPX2, RAP1A, MDC1, NSBP1, DNAJC9, GPSM2, CCDC21, CSTF1, TRIB3, PHF17, NUCKS1, CCNB1, BAG5, USP47, RPE, HMGB3, PCBP1, RCOR1, RPS27L, ZNF93, PPA2, PLS1, BLM, ASPM, SENP6, PRUNE, NRN1, DNAJB1, ORC1L, HMMR, PIAS2, PTPLAD1, MIS12, CACYBP, SLC25A14, NUDT4 /// NUDT4P1, PRIM1, RFC3, PCNA, RBBP4, CHAF1B, SERP1, EXO1, CRYZL1, NUP85, CDCA3, GINS1, MCM6, TBCE, RAD54B, PPP2R5C, RUVBL1, NFYB, TMEM70, SMC3, SEPT10, GRK5, DNMT1, PXMP3, NMT1, GMNN, SFRS1, GTF2A2, TAF5, TACC3, KIF2C, FBXO22, BIRC5, DHX8, SEPHS1, WHSC1, SSX2IP, PLK1, PLP2, RAD51C, DDB2, MCM10, PRPS1, UCHL5, ICMT, NAP1L4, SIP1, STAU2, CYB5B, H2AFY2, TFDP1, KNTC1, ASF1A, TPRKB, GALK2, SAE1, CTH, MTMR4, CCNB2, MSH6, LARP4, NET1, ANP32A, MCM7, USP21, ARMC1, PRC1, KIAA1462, MRPL39, POLE3, CASC5, CENPA, ZNF232, COQ9, ADH5, FLI1, C9ORF40, TYMS, CDT1, MCM5, CLN6, C1ORF112, CHEK1, HS2ST1, GMCL1, TUBB6, GEMIN4, CKAP2, CEP55, ASRGL1, PPP1R8, TMEM48, RACGAP1, C12ORF48, CDS1, RPA1, C12ORF29, MRPL48, RRM2, ZWINT, DNAJC12, CCDC99, NARS2, TOP2A, CNOT1, KIAA0101, FEN1, WRB, DDX39, FBXO28, LSM4, PLK4, SNAPC5, CMAS, RFC4, MAPRE1, OIP5, COIL, HIST1H4C, SNRPA, TUBG1, TTK, NUP50, CDC25C, STIP1, CDKN3, NCAPD2, CRYZ, BUB1, DCP2, SLC3A2, NCAPG, RFC5, FTSJ2, EIF4EBP1, GYG2, PSMD10, C17ORF42, CDC6, COPS3, NUP88, KCTD9, TMEM97, HRSP12, MCM2, PASK, DIDO1, SLC1A5, ZWILCH, GGA2, SHMT1, NUDT21, WWP1, TRIP13, KIF18A, MYBL2, TCEA1, AARS, PTTG1, TSN, PRKAA1, MKRN2, KIF15, USP1, HSPC157, CENPM, CASP8AP2, PPP1R7, RTCD1, CNIH4, DBF4, POGK, GINS2, CDC7, PAK2, AURKA, CDC2, FAM64A, ORC5L, CENPF, NUSAP1, MSH2, SLC29A1, WEE1, NSFL1C, ZW10, CDK2, EAF2, TRPM4, BUB1B, FANCG, BCAS4, RRM1, ITGB3BP, WDR76, ECT2, DEPDC1, SRR, RAD51AP1, PARP11, MYB, CDC25A, CTSC, CDCA8 |
| STEIN ESRRA TARGETS UP | SLC31A1, MGST3, TOMM70A, ST3GAL5, SLC25A20, CALU, NDUFS8, EGLN1, FASTKD1, TACC2, MUT, PDHA1, GABARAPL1 /// GABARA, NDUFS2, PAFAH2, GMCL1, NANS, NAGPA, GTPBP8, EPN3, MRPS11, PPP2R2D, NUDT3, RNF34, IMMT, KCNK13, PLA2G12A, OBFC1, ANXA6, ACAT1, PECI, RAB17, NNT, MLYCD, C6ORF162, ALDH3A2, CCDC121, AURKA, NDUFB5, MRPS22, PCTP, UQCRC1, ATP2A3, MDH1, CASP9, METTL7A, RNF14, OSBPL1A, MRPL34, NDUFS3, MAEA, EBP, ESRRA, ZNF576, SDHB, GSTK1, OXA1L, MRPL35, BDH2, TIMM8A, ACAA2, SLC16A3, OTUB2, FANCF, DSCR3, RNF4, PCYT2, RNF5, CTSC, ENDOG, C17ORF81 |
| BLUM RESPONSE TO SALIRASIB DN | POLA1, TOP2B, TMPO, AURKB, CENPA, SFRS6, CARHSP1, HSPA14, TYMS, ABCD3, MCM3, TUBB, MCM5, DHCR24, KIF22, HSPB1, CHEK1, ABCC6, RNASEH2A, TK1, FZD2, VDAC3, CD37, DBP, CSE1L, PAFAH1B3, CDC20, ID1, TPX2, PTPN4, GPSM2, RPA1, RRM2, PACSIN2, HN1, ZWINT, TUBB3, HMGB3, TOPBP1, TOP2A, RECQL4, FEN1, CBFB, DDX39, RAB4A, H2AFZ, SPAG5, RBBP7, PLK4, ORC1L, NPAT, RFC4, HMMR, B3GNT1, CCNA2, TUBG1, TTK, NUP50, CDC25C, PRIM1, RFC3, CDKN3, PCNA, CHAF1B, BUB1, GTF3C2, PBK, EXO1, NCAPG, RFC5, ZNF443, CDC6, MCM6, VAV3, MCM2, NPEPPS, SMC1A, BARD1, NARF, SHMT1, NFYB, DNMT1, TRIP13, SMARCE1, DUT, GMNN, MYBL2, SFRS1, PTTG1, CBX1, MRE11A, TACC3, USP1, KIF15, TROAP, SLC9A3R1, KIF2C, HDAC1, KIF20A, CASP8AP2, NME4, PLK1, STMN1, CDC7, GINS2, AURKA, CDC2, PRPS1, CENPF, GAMT, NUSAP1, STIL, MSH2, UBE2C, TFDP1, CKS2, CDK2, EBP, PXMP2, BUB1B, HIRIP3, RRM1, ITGB3BP, MAPRE2, RPA3, POLD1, CCNB2, MSH6, ANP32A, TUBB2C, RAD51AP1, H2AFV, ACLY, PRC1, CDC25A, H2AFY |
| RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED UP | CASC5, TMPO, DNM1L, RAP2A /// RAP2B, LEPRE1, MTIF2, CALU, HSPA14, TYMS, ABCD3, GMPS, GSR, CHEK1, RNASEH2A, DIAPH3, C1ORF103, HIST3H2A, CKAP2, VPS35, INTS7, CSE1L, NUP155, TMEM48, FAF1, DTL, RACGAP1, C12ORF48, ME2, NP, DNAJC9, GPSM2, HN1, RSRC1, ELOVL6, ZWINT, MLF1IP, NMD3, CCNB1, CCDC99, USP47, HMGB3, TOPBP1, AP2S1, MICAL2, FEN1, TPR, ACP1, CBFB, CCDC14, DDX39, RASAL2, C12ORF35, SERPINH1, H2AFZ, CEBPG, SUPT16H, RFC4, CCNA2, SNX13, TUBG1, DYNC2H1, CACYBP, XRCC4, PCNA, RBBP4, PBK, NCAPG, PHTF2, SCD, GINS1, EIF4EBP1, CDC6, TMEM97, MCM2, MRPS16, PHGDH, ZWILCH, SMC3, SEPT10, PPP1R14B, DNMT1, AGPS, NUDT21, KIF18A, TSN, CYP51A1, C18ORF10, PRKAA1, USP1, KIF2C, NNT, RTCD1, SSX2IP, RAD51C, DBF4, GINS2, STMN1, AURKA, CDC2, GALC, ORC5L, GNAI1, CENPF, SIP1, NUSAP1, STIL, UBE2C, UBE2W, CKS2, KNTC1, SSR1, BUB1B, FXR1, ITGB3BP, RRM1, GLRX2, CKLF, ECT2, LEPROTL1, MSH6, PSPH, PMS1, DCUN1D4, MCM7, CBARA1, RAD51AP1, YIPF5, HAT1, PRC1, CTSC |
| HORIUCHI WTAP TARGETS DN | CDKN3, POLA1, NCAPD2, HMGCR, BUB1, CASC5, TMPO, AURKB, CENPA, PBK, RFC5, PEX13, CDCA3, TYMS, ABCD3, FECH, GSR, KIF22, TK1, TMEM97, IMPDH2, PPM1A, CKAP2, CNN2, SHMT1, SEPT10, TRIP13, GMNN, RACGAP1, PTTG1, UNG, GLO1, FDFT1, CCDC21, KIF2C, BIRC5, KIF20A, SC5DL, RRM2, SEPHS1, PLK1, PLP2, NUCKS1, CCNB1, AURKA, FAM64A, TOP2A, SMAD2, KIAA0101, NUSAP1, SMAD5, DCXR, UBE2C, CKS2, LSM4, DRG2, ING3, ASPM, BUB1B, ASF1A, CAT, RRM1, ODC1, HMMR, OIP5, POLD1, CCNA2, HIST1H4C, CCNB2, LEPROTL1, LBR, DEPDC1, SLC25A5, MCM7, RAD51AP1, H2AFV, PRC1, CDCA8 |
| SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN UP | SNAP29, RBBP4, ZNF330, CCDC85B, ZNF232, HDGFRP3, B4GALT7, NCAPG, SLC12A9, NDUFS8, BLOC1S1, OPHN1, STT3A, FTSJ2, EIF4EBP1, EIF4G3, GMPS, DHCR24, TM6SF1, KIF22, HSPB1, MEF2D, CCR10, POLRMT, MYL6B, ATPIF1, TAX1BP3, NARF, NUDT3, MAD1L1, TP53, APAF1, TCEA1, PIN4, ZNF84, IFNGR1, SPA17, PTTG1, RAP2B, TAF5, PHKA2, ZNF544, TACC3, HSD17B4, NAGLU, DHCR7, HDAC1, KIF20A, SEC22A, DDB2, PTPN6, AURKA, IVD, HMGB3, ICMT, TOP2A, CENPF, NSDHL, UQCRC1, PET112L, RPS27L, RECQL4, IL27RA, DCXR, CDK2AP2, UBE2C, BCAT2, PPA2, CKS2, LSM4, EBP, HMBS, SPAG5, H2AFX, PIGB, CACYBP, ETV5, H2AFV |
| ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE UP | MGST3, IARS2, GTF3C2, RIOK2, GMDS, SERP1, EXOSC5, STT3A, ICT1, HSPA14, TYMS, IGBP1, LGTN, MCM3, ATP5S, GMPS, LSM3, MCM5, MRPS18B, TBCE, RNASEH2A, TK1, ZNF329, DPH5, RPP21, VPS35, FARS2, SMC3, AMZ2, DNMT1, MRPL18, DTL, GMNN, TAF12, NUP37, ACBD3, IDH1, MDC1, NAGA, TBC1D2, TMCO3, DNAJC9, C14ORF166, MKRN2, RPA1, IDI1, TSSC1, AP3S1, RSRC1, DHX35, POGK, GINS2, AURKA, SLC39A1, KLHL12, TRIM27, NUP133, NDUFB5, MID1IP1, THAP11, NUSAP1, PIGC, APEX1, WRB, C10ORF26, CDK2AP2, TOM1L1, SLC2A10, TMEM14A, CKS2, TFDP1, LSM4, GOLPH3L, GPKOW, SURF1, ASPM, LRRC42, KIAA0196, SERPINH1, HPRT1, ATRN, OXA1L, TMED10, LRRC8D, RBBP7, CYBRD1, ODC1, TIMM8A, RFC4, RPA3, PIGB, CCNA2, IL10RB, MSH6, CCDC51, TUBB2C, TBL2, PRC1, C14ORF147, IK, DEPDC6 |
| KOBAYASHI EGFR SIGNALING 24HR DN | RFC3, CDKN3, PCNA, POLA1, BUB1, TMPO, AURKB, CENPA, PBK, NCAPG, EXO1, PARP2, RFC5, CDCA3, HSPA14, TYMS, GINS1, NCAPH, MCM3, MCM5, CDT1, CDC6, MCM6, TK1, RNASEH2A, TUBB6, RAD54B, MCM2, CEP55, BARD1, CSE1L, ZWILCH, TRIP13, DUT, DTL, GMNN, RACGAP1, MYBL2, TPX2, UNG, DNAJC9, GPSM2, KIF15, USP1, KIF2C, BIRC5, CENPM, ZWINT, PLK1, DBF4, CCNB1, GINS2, AURKA, CCDC99, MCM10, CDC2, PRPS1, FAM64A, TOP2A, NUSAP1, FEN1, STIL, SLC29A1, MSH2, UBE2C, TFDP1, CKS2, ACOX2, BLM, ASPM, BUB1B, SPAG5, PLK4, RRM1, ORC1L, ODC1, RFC4, H2AFX, HMMR, CCNA2, HIST1H4C, CKLF, ECT2, TUBG1, MSH6, DEPDC1, ETV5, MCM7, RAD51AP1, HAT1, TUBB2C, POLR3K, PRC1, CDC25A, CDCA8, PRIM1 |
| MANALO HYPOXIA DN | RFC3, PBK, GNPDA1, EXO1, PARP2, RFC5, NUP85, GINS1, MCM3, MCM5, CDC6, DHCR24, MCM6, GPD1L, C1ORF112, NVL, MCM2, BARD1, CSE1L, SLC1A5, ZWILCH, PRMT7, RUVBL1, COQ2, TRIP13, GMNN, C12ORF48, ID1, TPX2, DNAJC9, USP1, NUP43, DHCR7, ZWINT, ELOVL6, FXN, DHX35, DBF4, GINS2, CDC7, NARS2, CCDC99, CDC2, MCM10, PRPS1, UCHL5, SIP1, KIAA0101, PET112L, NUSAP1, FEN1, STIL, POP5, RSAD1, TOP3A, NIF3L1, HMBS, C11ORF48, C12ORF52, SLC25A15, FANCG, RRM1, SNAPC5, ODC1, H2AFX, OIP5, PTPLAD1, CCNA2, GLRX2, TUBG1, MNS1, RPL39L, RAD51AP1, TUBB2C, PCYT2, POLR3K, PRC1 |
| SHEN SMARCA2 TARGETS UP | GMPR2, TRAK2, PRKAR1A, DCP2, CDKN1B, LMBRD1, CRYZL1, ROCK1, AASDHPPT, ATP5O, RWDD3, C20ORF30, UPF2, ATRX, METTL5, C1ORF77, BAZ2B, XPO1, COPS4, PPP2R5C, VPS26A, SUCLG2, BUB3, GTF2H5, SCFD1, XPA, DCTN4, NPEPPS, GYG1, PHKB, DPM1, SMC1A, CSE1L, UBE2G1, NFYB, BTBD3, SMC3, SEPT10, TMEM41B, NUDT21, PCMTD2, CUL4B, AMZ2, HIPK1, HSDL2, HMG20A, PTPN11, FTO, TSN, CBX1, XRCC5, WDR61, MORF4L1, IKBKAP, KIAA0494, HIBCH, RPA1, USP1, APC, TWSG1, ANGEL2, PON2, ZMYND11, NNT, SEPHS1, INSIG2, SOS2, RAF1, PEX11B, DHX29, ANKMY2, MAPK9, RNF130, MAP4K3, NUP133, SPTLC1, RBM16, MKKS, SMAD2, CDC23, PPWD1, SHOC2, TMEM14A, NSFL1C, ST13, FBXO28, TMEM135, RNF14, OSBPL1A, RAB4A, GBE1, UQCRC2, FBXW11, SNX5, UNC50, YTHDC1, PDHB, SENP6, GTF3C3, ORC4L, TMED10, CAMSAP1, RNF146, DERA, PCMT1, TMEM14B, APPBP2, KIAA0355, CEP57, RASA1, PCNP, SUCLG1, ANP32A, HAT1, H2AFV, RAB28, TRAPPC4, MRFAP1L1, RHOT1, C6ORF211 |
| FOURNIER ACINAR DEVELOPMENT LATE 2 | RFC3, CDKN3, POLA1, POLE3, TMPO, DNM1L, CENPA, MRPL3, PHTF2, PARP2, NUP85, CDCA3, SCD, FASTKD1, GINS1, MCM3, PDLIM7, PITRM1, NASP, CDC6, VCL, MCM6, RNASEH2A, TFB1M, POLRMT, MCM2, CDC45L, BARD1, CSE1L, TMEM48, GEMIN6, ITGB5, TRIP13, DUT, DTL, RACGAP1, ME2, PTTG1, NUP37, CYP51A1, DNAJC9, IDI1, USP1, KIF2C, BIRC5, ELK3, RRM2, ZWINT, ELOVL6, WHSC1, PLK1, DBF4, CDC7, GINS2, AURKA, CDC2, PRPS1, UCHL5, ANAPC5, PFN1, NUSAP1, FEN1, ALG8, CKS2, CNOT7, CDK2, NIF3L1, BLM, HMBS, ASPM, TTLL12, SH3TC1, TPRKB, LDLR, H2AFZ, SUPT16H, MRPL35, ODC1, RPA3, PTPLAD1, SAE1, TUBG1, TTK, MSH6, CAMSAP1L1, DEPDC1, LARP4, PMS1, MCM7, HAT1, H2AFV, PRC1, CDC25A, NT5DC2 |
| MITSIADES RESPONSE TO APLIDIN DN | NCAPD2, ZFP64, BUB1, CENPA, DCP2, KCTD12, NCAPG, SCD, TYMS, NCAPH, GINS1, GMPS, TUBB, RAP2A, MCM5, CDT1, TMEM106C, DHCR24, KIAA0100, TMEM97, CKAP2, MCM2, FUT8, CSE1L, TMEM48, SMC3, TOMM20, TRIP13, ADD3, DUT, RACGAP1, CLTC, PIK3CB, TPX2, PTTG1, C18ORF10, TACC3, BIRC5, RRM2, RSRC1, ZWINT, WHSC1, NUCKS1, CCNB1, NGLY1, CDC7, AURKA, TOPBP1, TOP2A, CENPF, NSDHL, CNOT1, KIAA0101, NUSAP1, TPR, CBFB, MSH2, WEE1, TFDP1, BLM, ASPM, BUB1B, SUPT16H, RRM1, RFC4, NF2, CCNA2, SNRPA, MTMR4, ECT2, PSMD2, MSH6, LBR, SFRS14, EIF4B, MYB, CDCA8, DEPDC6 |
| BUYTAERT PHOTODYNAMIC THERAPY STRESS DN | CDKN3, VANGL1, GMPR2, BUB1, STX10, TRMT12, AURKB, GTF3C2, CCDC85B, SLC25A20, PARP2, EXO1, CTNNBIP1, STX8, CDCA3, C9ORF40, MCM3, ZDHHC4, ANTXR1, VCL, C1ORF156, C1ORF112, EXTL2, HRSP12, XPA, UBTF, ABHD14A, CNN2, BARD1, CCDC15, PPP2R2D, ACP6, SHMT1, TMEM160, M6PR, DUT, ETFB, POLM, ID1, SLC26A2, PYCARD, TBC1D2, TCTA, ID3, TM7SF3, MANSC1, CSTF1, IMP3, BIRC5, KIF20A, TGFBR2, PHF17, THAP10, SEPHS1, MRPS34, SSX2IP, DBF4, RAD51C, CDC7, GINS2, AURKA, ZNF238, TRIAP1, FAM64A, IVD, TOP2A, LIPT1, THAP11, ZNF93, ZFP161, TMEM14A, POP5, MRP63, THYN1, MRPL34, OSTF1, EBP, HMBS, PXMP2, TTLL12, LCMT2, HOXA1, ATRN, BDH2, ORC1L, TIMM8A, B3GNT1, CCNA2, DERA, CKLF, PTDSS1, C14ORF109, NUDT6, ANP32A, C14ORF147, CTSC, EHMT2, ENDOG, DEPDC6, C17ORF81, PRIM1 |
| UDAYAKUMAR MED1 TARGETS UP | MTDH, ASPH, TMPO, SSX2IP, THOP1, DCP2, AURKA, MRPL12, SDF2L1, STX6, ANAPC5, RDH11, OGG1, KIAA0101, EIF4EBP1, SLC29A1, FECH, CDC6, KDELC1, ACSL3, DUS1L, LRRC14, TSPAN12, DDHD2, COX4NB, BRD9, MAD1L1, SLC16A3, PSPH, LBR, CAMSAP1L1, ME2, LARP4, NSMAF, NUBP2, NAGLU |
| BASAKI YBX1 TARGETS UP | CDKN3, ARPC5L, NCAPD2, BUB1, AURKB, CENPA, SLC3A2, PBK, S100A2, RFC5, PEX13, CDCA3, TYMS, GINS1, MCM3, PDLIM7, MCM5, CDC6, KIF22, CHEK1, TK1, TUBB6, DIAPH3, MCM2, CEP55, SLC1A5, ZWILCH, C13ORF34, TRIP13, DTL, KRT10, TPX2, PTTG1, UNG, MDC1, DNAJC9, KIF2C, BIRC5, CENPM, KIF20A, HN1, ZWINT, WHSC1, PLK1, CCNB1, GINS2, DDB2, CCDC99, AURKA, CDC2, MCM10, COTL1, DR1, CDK2AP2, UBE2C, FOXE1, COMMD4, ASPM, BUB1B, TPRKB, H2AFX, OIP5, CCNA2, GLRX2, SAE1, CTH, CCNB2, RRAS, DEPDC1, CACYBP, MCM7, HAT1, TUBB2C, H2AFV, PRC1, CDCA8 |
| KEGG PYRUVATE METABOLISM | MDH1, ACAT1, GRHPR, PDHB, ME2, ALDH3A2, DLAT, ALDH7A1, PDHA1, GLO1 |
| REACTOME CELL CYCLE MITOTIC | PCNA, CDC16, POLA1, BUB1, CASC5, ORC3L, PPP1CC, AURKB, CENPA, RFC5, NUP85, TYMS, GINS1, MCM3, PSMD10, MCM5, CDT1, CDC6, PPP2R5C, MCM2, DCTN3, CEP63, ZWILCH, SMC3, MAD1L1, KIF18A, GMNN, PTTG1, NUP37, ODF2, RPA1, KIF2C, BIRC5, KIF20A, POLD4, RRM2, ZWINT, TK2, PLK1, CCNB1, DBF4, GINS2, CDC7, CCDC99, AURKA, NUP133, ANAPC5, ORC5L, CENPF, FEN1, CDC23, UBE2C, WEE1, TFDP1, KNTC1, BUB1B, CDK5RAP2, CCNH, TUBGCP5, PLK4, ITGB3BP, ORC1L, RFC4, RPA3, MAPRE1, POLD1, CCNA2, MIS12, PSMD2, CCNB2, CEP57, MCM7, TUBB2C, CDC25A, CDCA8, PRIM1 |
| SHEDDEN LUNG CANCER POOR SURVIVAL A6 | CDKN3, PCNA, VANGL1, NCAPD2, BUB1, DNM1L, AURKB, CENPA, PBK, SLBP, MRPL12, MTIF2, HDGFRP3, EXO1, NCAPG, PHTF2, CARHSP1, CDCA3, SCD, TYMS, GINS1, NCAPH, EIF4EBP1, MCM5, CDT1, CDC6, CHEK1, TK1, FIP1L1, C1ORF103, GGH, CDK5R1, PYGL, SAP30, CKAP2, CEP55, ZWILCH, NUDT3, TRIP13, DTL, KIF18A, RACGAP1, C12ORF48, TPX2, TFPT, PTTG1, NUP37, DNAJC9, GPSM2, TACC3, KIF15, KIF2C, BIRC5, TSSC1, KIF20A, SEPHS1, HN1, WHSC1, ZWINT, ELOVL6, SSX2IP, DBF4, CCNB1, GINS2, CDC7, STMN1, AURKA, CDC2, PRPS1, FAM64A, DR1, TOP2A, CENPF, AP2S1, KIAA0101, NUSAP1, RECQL4, ACD, UBE2C, CKS2, TFDP1, LSM4, KNTC1, RASAL2, ZNF248, ASPM, BUB1B, TPRKB, SPAG5, PLK4, ORC1L, CMAS, TIMM8A, TNNT1, RFC4, H2AFX, OIP5, HMMR, CCNA2, COMMD8, WDR76, CCNB2, PCMT1, TUBG1, MSH6, SLC16A3, DEPDC1, PGM3, HAT1, RAD51AP1, PRC1, CDC25A, CDCA8, PRIM1 |
| ZHANG BREAST CANCER PROGENITORS UP | NCAPD2, PHF17, CRYZ, BUB1, TMPO, CDC40, DBF4, STMN1, MRPS33, AURKA, LPHN3, PBK, WIF1, RPE, ORC5L, TOP2A, TOPBP1, NUP85, ADH5, CALM2, METTL9, TRIM37, CDC6, WEE1, CHEK1, ING3, BUB1B, NVL, HRSP12, SAP30, MCM2, TULP3, NUP155, SHMT1, RPA3, CCNA2, TRIP13, CTH, RNF7, GMNN, PLEKHB1, APPBP2, ADK, DNAJC9, EIF4B, GPSM2, MYB, RPA1, CDC25A, IK, USP1, CDCA8, PCYOX1, KIF2C, EPS8, PRIM1 |
| MISSIAGLIA REGULATED BY METHYLATION DN | CDKN3, TMPO, ZWINT, STMN1, HMGB3, RFC5, CENPF, TYMS, KIAA0101, NUSAP1, GMPS, MCM5, CDT1, UBE2C, CDC6, KIF22, CHEK1, TK1, RNASEH2A, NDUFS3, KNTC1, EBP, BUB1B, H2AFZ, FUT8, CSE1L, RRM1, SHMT1, RFC4, RPA3, CCNA2, DNMT1, DUT, PSIP1, GMNN, MSH6, LBR, MDC1, CBARA1, HAT1, PRC1, ANP32B, PRIM1 |
| GOLDRATH ANTIGEN RESPONSE | CDKN3, PCNA, SLC31A1, BUB1, TMPO, AURKB, CENPA, GNPDA1, CARHSP1, RFC5, CDCA3, NCAPH, MCM5, CDC6, VCL, KIF22, CHEK1, WBP5, TK1, MXD3, NCF4, TMEM97, GGH, ATPIF1, CKAP2, ARL5A, DOCK5, TRIP13, MRPL18, DTL, GMNN, RACGAP1, TACC3, BIRC5, KIF20A, SSX2IP, PLK1, PLP2, CCNB1, STMN1, CCDC99, AURKA, KLRK1, IGJ, TOPBP1, TOP2A, NUSAP1, H1F0, WEE1, CCR2, CKS2, ASPM, EBP, HMBS, CD244, PLK4, MAPRE2, CYFIP1, ODC1, RPA3, CCNA2, CCNB2, ECT2, CPOX, PGM1, REEP5, RAD51AP1, H2AFV, PRC1, TBL2, CDCA8, ITGA4, PRIM1 |
| PUJANA BRCA CENTERED NETWORK | RFC3, PCNA, RBBP4, TAF11, TMPO, PPP1CC, RAD51C, DCP2, AURKA, PRPS1, TOP2A, TOPBP1, KATNA1, MSH2, MCM5, UBE2C, DDX39, MCM6, TFDP1, COPS3, PPP2R5C, BLM, ASF1A, NCK1, MCM2, RRM1, RFC4, NFYB, HMMR, CCNA2, SNRPA, DNMT1, MCM4, DUT, MYBL2, CDC20, LBR, RAD54L, UNG, MRE11A, RPA1 |
| KIM WT1 TARGETS DN | ACTR6, ZFP64, BUB1, TMPO, AURKB, CENPA, GLT8D1, SERP1, CCDC85B, NCAPG, PARP2, RDH11, CDCA3, FASTKD1, RWDD3, ABCD3, EIF4EBP1, MRPS18B, HOXB6, RAB7L1, KIF22, PPP2R5C, GTF2H5, PPM1A, CDK5R1, FZD2, CKAP2, CEP55, BARD1, UBE2G1, TMEM48, PRMT7, SMC3, GRK5, APAF1, TMEM160, PLA2G12A, KIF18A, GMNN, RACGAP1, KRT10, ID1, RAP2B, SLC26A2, PPM1B, GPSM2, REPIN1, KIF2C, IMP3, KIF20A, C6ORF130, POLD4, PPM1D, SHMT2, ELOVL6, CDC40, DBF4, RAD51C, CDC7, AURKA, ZNF238, DERL2, CDC2, TRIM27, TST, FAM64A, ELOVL1, C14ORF106, ORC5L, TOP2A, CENPF, LIPT1, SIP1, THAP11, HOXA9, GADD45GIP1, NUSAP1, CDK2AP2, PPWD1, POP5, CKS2, LSM4, MRPL34, GOLPH3L, NIF3L1, ASPM, BUB1B, C12ORF41, ASF1A, FXR1, OXA1L, VAMP4, DNAJB1, OIP5, CCNA2, CKLF, DERA, ARL6IP1, CPOX, FAM82B, MNS1, APPBP2, SFRS14, CEP57, LARP4, NUDT6, NET1, PMS1, ARMC1, RAD51AP1, H2AFV, C14ORF147, CDCA8, STIP1, ITGA4 |
| MUELLER PLURINET | PCNA, TMPO, CCNB1, CDC7, AURKB, PTPN6, AURKA, EXO1, RFC5, HSPA14, MCM3, APEX1, MSH2, GMPS, MCM5, CDT1, WEE1, CASP9, NPPB, DHCR24, SP1, CKS2, COPS3, CHEK1, LSM4, TK1, VAMP8, C1ORF103, BUB1B, MCM2, PASK, ITGB3BP, PHGDH, ORC1L, PAK1, RFC4, RUVBL1, RPA3, PIAS2, HMMR, POLD1, CCNA2, TRIP13, PSIP1, CCNB2, GMNN, MSH6, ANP32A, MRE11A, MYB, RPA1, CTBP2, BIRC5 |
| LINDGREN BLADDER CANCER CLUSTER 3 UP | PCNA, RBBP4, CHAF1B, TAF11, BUB1, TMPO, CENPA, SERP1, EXO1, TYMS, MCM5, CDT1, CDC6, TMEM106C, RNASEH2A, TK1, GMCL1, TMEM97, GGH, SHMT1, TRIP13, FAF1, GMNN, RACGAP1, PTTG1, MDC1, TACC3, MKRN2, CCDC21, IDH2, KIF2C, BIRC5, PPM1D, ANKRD27, ZWINT, PLK1, CCNB1, DBF4, RAD51C, GINS2, CDC7, STMN1, AURKA, TOP2A, CENPF, PIGC, TOM1L1, MSH2, UBE2C, PPA2, SNX4, ZNF148, CKS2, DAB2, EBP, PLK4, RBBP7, ORC1L, RFC4, RPA3, CCNB2, MNS1, DEPDC1, PGM3, H2AFV, PRC1, CDC25A, CDCA8 |
| BENPORATH CYCLING GENES | CDKN3, SNUPN, PCNA, VANGL1, CDC16, PKNOX1, CHAF1B, NCAPD2, HMGCR, BUB1, TMPO, ORC3L, AURKB, CENPA, PBK, SLBP, EXO1, CDCA3, NCAPH, MCM5, CDC6, ANTXR1, MRPS18B, VCL, KIF22, HIST1H4B, C1ORF103, HIST3H2A, ENOSF1, HRSP12, SAP30, CKAP2, MCM2, INTS7, CNN2, PASK, BARD1, C13ORF34, RNF113A, USP53, TRIP13, DTL, GMNN, HP1BP3, TXNDC9, PTTG1, UNG, NUP37, NUDT13, KIAA1598, MDC1, RAB3A, GPSM2, TACC3, ODF2, USP1, HSPC157, KIF2C, DHX8, BIRC5, SEPHS1, INSIG2, HN1, ZWINT, PLK1, RAD51C, NUCKS1, CCNB1, GINS2, CDC7, AURKA, CCDC99, FAM64A, DR1, HMGB3, TOPBP1, TOP2A, CENPF, KATNA1, KIAA0101, NUSAP1, RECQL4, NIPBL, MSH2, ACD, CCDC14, UBE2C, CKS2, KCTD2, BUB1B, FXR1, DNAJB1, ORC1L, RFC4, HMMR, MAP3K2, HIST1H4C, CCNA2, CCNB2, ARL6IP1, LBR, ARMC1, RAD51AP1, TUBB2C, PRC1, CDC25A, ANP32B, CDCA8, HDAC3, PRIM1 |
| WINNEPENNINCKX MELANOMA METASTASIS UP | CDKN3, PCNA, RSRC1, WHSC1, ZWINT, BUB1, CCNB1, GINS2, CENPA, AURKA, NCAPG, EXO1, TOP2A, RFC5, CENPF, C9ORF40, TYMS, OGG1, KIAA0101, NCAPH, GMPS, CDC6, CKS2, CHEK1, TK1, KNTC1, ASPM, CEP55, SPAG5, RFC4, RPA3, IMMT, GLRX2, CCNB2, ECT2, RACGAP1, GMNN, C12ORF48, MSH6, PTTG1, CACYBP, H2AFV, PRC1, CDCA8, KIF2C, BIRC5 |
| BENPORATH PROLIFERATION | CDKN3, PCNA, RRM2, CHAF1B, ANKRD27, BUB1, DBF4, STMN1, CENPA, AURKA, PBK, NDUFB5, EXO1, TOP2A, CENPF, HSPA14, TYMS, SMAD2, MCM3, FANCE, MSH2, CDT1, TMEM14A, CKS2, C11ORF73, C1ORF112, ASPM, ASF1A, H2AFZ, CEBPG, MCM2, CSE1L, RFC4, DTL, CCNB2, RACGAP1, LBR, PTTG1, SLC25A5, RAD51AP1, H2AFV, GPSM2, PRC1, IDH2, BIRC5 |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER UP | C17ORF71, PPM1D, TMEM97, HN1, DHX40, ALDH3A2, RAD51C, GTF3C2, MRPL12, UTP18, TOP2A, BAIAP2, STX8, SGSH, NUP85, ICT1, ATP2A3, SEC14L1, NAT9, CDC6, SRR, ATPAF2, AKAP1, ABCC3, TK1, DHRS7B, PMP22, BIRC5 |
| BIDUS METASTASIS UP | SFRS9, RBBP4, WHSC1, BUB1, CASC5, DBF4, CCNB1, PAK2, CENPA, AURKA, CKAP5, PBK, MCM10, CDC2, HMGB3, RCOR1, RFC5, CENPF, NCAPH, NUSAP1, WRB, CBFB, PSMD10, CDC23, UBE2C, CDC6, TFDP1, CHEK1, ZNF550, CEBPG, PLK4, CCDC15, ADNP, ODC1, RFC4, CCNA2, ECT2, CCNB2, GMNN, RACGAP1, MNS1, TPX2, DEPDC1, CEP57, SFRS1, LARP4, SMC4, H2AFY, BIRC5, NDRG3 |
| BOYAULT LIVER CANCER SUBCLASS G3 UP | HN1, NCAPD2, RBBP4, FNBP1L, BUB1, NARS, PPP1CC, STMN1, NCAPG, TOPBP1, SMAD2, CDC6, TPD52L2, C17ORF71, USP3, KIAA0196, TPRKB, FXR1, NPEPPS, CEP55, NUP155, ZWILCH, UTP18, HMMR, COIL, CCNA2, TRIP13, CKLF, NSF, TTK, SLC16A3, DUSP3, NUP37, RAD51AP1, TACC3, KIF2C, PRIM1, CENPM |
| MOREAUX MULTIPLE MYELOMA BY TACI DN | NNT, ACTR6, DBF4, GLT8D1, DHX29, CDC2, AASDHPPT, ORC5L, TYMS, PMS2L3, DDX18, FIBP, ACD, CDC23, C17ORF42, NASP, TERF1, TMEM165, C11ORF73, TMEM135, SPAST, CHEK1, LSM4, COMMD4, PPP2R5C, BUB3, LSM5, PDCD6, ASF1A, MCM2, BARD1, RACGAP1, NMT1, CEP57, ANKRD49, FANCF, WDR61, SF3B2, IK, LRRC40 |
| ZHONG RESPONSE TO AZACITIDINE AND TSA DN | PPIE, TBC1D5, HDAC4, LSM7, NUCKS1, NGLY1, ITGB3BP, DIAPH2, C6ORF48, ARHGEF9, HIST1H4C, CCNA2, ICT1, LGTN, PET112L, TOM1L1, PMS1, GLTSCR2, CIRBP, ANP32B, KIF15, GOLPH3L, SUCLG2, PPP2R5C, RBMX |
| REACTOME MITOTIC M M G1 PHASES | KIF20A, ZWINT, BUB1, CASC5, PLK1, ORC3L, PPP1CC, AURKB, CENPA, CCDC99, NUP133, ORC5L, CENPF, NUP85, MCM3, PSMD10, MCM5, CDT1, CDC6, KNTC1, PPP2R5C, BUB1B, MCM2, ZWILCH, ITGB3BP, ORC1L, SMC3, MAD1L1, MIS12, KIF18A, GMNN, NUP37, MCM7, CDCA8, KIF2C, BIRC5 |
| REACTOME CELL CYCLE CHECKPOINTS | BUB1B, CDC16, MCM2, ORC3L, DBF4, CCNB1, CDC7, ORC1L, MCM10, RFC4, RPA3, MAD1L1, ORC5L, ANAPC5, RFC5, TP53, CCNB2, MCM3, CDC23, MCM5, CDC25C, UBE2C, CDC6, WEE1, MCM6, CHEK1, RPA1, CDC25A |
| MARKEY RB1 ACUTE LOF DN | KIF20A, CDKN3, PCNA, CHAF1B, RBBP4, BUB1, TMPO, PLK1, NUCKS1, CCNB1, STMN1, CENPA, CCDC99, AURKA, MTCP1, ANAPC5, TOPBP1, RFC5, CDCA3, NUSAP1, NIPBL, LSM3, TRIM37, MCM5, CDT1, CDC6, CKS2, TFDP1, KIF22, LSM4, TK1, CKAP2, RFC4, SMC3, CCNA2, TRIP13, PSIP1, DTL, CCNB2, RACGAP1, GMNN, DNAJC9, RAD51AP1, MRE11A, H2AFV, PRC1, IDH2, PRIM1, BIRC5 |
| CREIGHTON AKT1 SIGNALING VIA MTOR DN | CIB1, TUBB2C, PAFAH1B3, PPP4C, MRPS7 |
| YU MYC TARGETS UP | CDKN3, KIF20A, PCNA, BUB1, PLK1, CCNB1, AURKA, TOP2A, DTL, RACGAP1, CCNB2, ECT2, GMNN, TFDP1, CKS2, IDI1, BIRC5, ASPM |
| CHANG CYCLING GENES | KIAA0101, CDKN3, GMNN, CCNB2, UBE2C, CENPA, GINS2, CKS2, AURKA, PBK, TACC3, USP1, TOP2A |
| REACTOME LAGGING STRAND SYNTHESIS | |
| FERRANDO HOX11 NEIGHBORS | |
| LI WILMS TUMOR VS FETAL KIDNEY 1 DN | |
| MONTERO THYROID CANCER POOR SURVIVAL UP | |
| BOYAULT LIVER CANCER SUBCLASS G123 UP | GINS1, KIF20A, CCNB2, PNMA1, TMPO, CACYBP, POGK, PRKCI, BARD1, HAT1, CBX1, RFC4, SMC4, NT5DC2, SAC3D1 |
| PAL PRMT5 TARGETS UP | |
| REACTOME REPAIR SYNTHESIS OF PATCH 27 30 BASES LONG BY DNA POLYMERASE | |
| NCI AURORA B PATHWAY | |
| NCI PLK1 PATHWAY | |
| MARKEY RB1 CHRONIC LOF UP | |
| REACTOME NUCLEOTIDE EXCISION REPAIR | |
| CORUM C COMPLEX SPLICEOSOME | |
| REACTOME PEROXISOMAL LIPID METABOLISM | |
| NCI VIRAL MESSENGER RNA SYNTHESIS | |
| NCI REPAIR SYNTHESIS FOR GAP FILLING BY DNA POLYMERASE IN TC NER | |
| FRASOR RESPONSE TO SERM OR FULVESTRANT DN | |
| REACTOME CHOLESTEROL BIOSYNTHESIS | |
| BOYAULT LIVER CANCER SUBCLASS G23 UP | |
| LE EGR2 TARGETS UP | |
| CORUM DNA SYNTHESOME COMPLEX 13 SUBUNITS | |
| REACTOME PYRUVATE METABOLISM AND TCA CYCLE | |
| REACTOME SYNTHESIS OF DNA | |
| NCI SYNTHESIS OF DNA | |
| REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | |
| REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | |
| WU APOPTOSIS BY CDKN1A VIA TP53 | |
| MORI IMMATURE B LYMPHOCYTE DN | |
| WAKASUGI HAVE ZNF143 BINDING SITES | |
| BOYAULT LIVER CANCER SUBCLASS G12 UP | |
| REACTOME MITOTIC PROMETAPHASE | |
| REACTOME POLYMERASE SWITCHING | |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | |
| NCI P53REGULATIONPATHWAY | |
| NCI DNA STRAND ELONGATION | |
| FINETTI BREAST CANCER BASAL VS LUMINAL | |
| NCI PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | |
| REACTOME REMOVAL OF THE FLAP INTERMEDIATE | |
| REACTOME G1 S TRANSITION | |
| NCI REPAIR SYNTHESIS OF PATCH 27 30 BASES LONG BY DNA POLYMERASE | |
| MORI LARGE PRE BII LYMPHOCYTE UP | |
| NCI PHENYLALANINE AND TYROSINE CATABOLISM | |
| VECCHI GASTRIC CANCER EARLY UP | |
| NCI MRNA SPLICING MINOR PATHWAY | |
| SONG TARGETS OF IE86 CMV PROTEIN | |
| FUJII YBX1 TARGETS DN | |
| CORUM PLC-GAMMA-2-SYK-LAT-FCR-GAMMA COMPLEX | |
| BENPORATH MYC MAX TARGETS | |
| BORCZUK MALIGNANT MESOTHELIOMA UP | |
| NCI REMOVAL OF THE FLAP INTERMEDIATE | |
| RHODES UNDIFFERENTIATED CANCER | |
| ODONNELL TARGETS OF MYC AND TFRC DN | |
| STEIN ESRRA TARGETS | |
| TARTE PLASMA CELL VS PLASMABLAST DN | |
| NCI ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | |
| ZHAN MULTIPLE MYELOMA PR UP | |
| MOLENAAR TARGETS OF CCND1 AND CDK4 DN | |
| NCI PHOSPHORYLASE KINASE ACTIVATES GLYCOGEN PHOSPHORYLASE | |
| REACTOME GLOBAL GENOMIC NER | |
| HOFFMANN LARGE TO SMALL PRE BII LYMPHOCYTE UP | |
| REACTOME TRANSCRIPTION COUPLED NER | |
| NCI MITOTIC PROMETAPHASE | |
| REACTOME DNA REPAIR | |
| NCI LAGGING STRAND SYNTHESIS | |
| KAUFFMANN DNA REPAIR GENES | |
| REACTOME DNA REPLICATION PRE INITIATION | |
| REACTOME TRANSFORMATION OF LANOSTEROL TO CHOLESTEROL | |
| NIKOLSKY BREAST CANCER 16Q24 AMPLICON | |
| ONKEN UVEAL MELANOMA DN | |
| NCI TRANSFORMATION OF LANOSTEROL TO CHOLESTEROL | |
| GARCIA TARGETS OF FLI1 AND DAX1 DN | |
| CHEMNITZ RESPONSE TO PROSTAGLANDIN E2 UP | |
| FURUKAWA DUSP6 TARGETS PCI35 DN | |
| NCI POLYMERASE SWITCHING | |
| DING LUNG CANCER EXPRESSION BY COPY NUMBER | |
| REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION | |
| BIOCARTA ERK5 PATHWAY | |
| REACTOME DNA STRAND ELONGATION | |
| NCI DNA REPLICATION | |
| KEGG PROPANOATE METABOLISM | |
| TOYOTA TARGETS OF MIR34B AND MIR34C | |
| RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY UP | |
| REACTOME EXTENSION OF TELOMERES | |
| RICKMAN METASTASIS UP | |
| NCI LEADING STRAND SYNTHESIS | |
| WEST ADRENOCORTICAL TUMOR UP | |
| NCI POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE | |
| CHIANG LIVER CANCER SUBCLASS PROLIFERATION UP | |
| NCI TELOMERE C STRAND LAGGING STRAND SYNTHESIS | |
| REACTOME S PHASE | |
| FINETTI BREAST CANCER KINOME RED | |
| KALMA E2F1 TARGETS | |
| VANTVEER BREAST CANCER METASTASIS DN | |
| PUJANA BREAST CANCER WITH BRCA1 MUTATED UP | |
| REACTOME GLUCOSE METABOLISM | |