| Gene Set | Leading Edge Genes |
|---|
| KEGG VALINE LEUCINE AND ISOLEUCINE DEGRADATION | ACADS, ACAT1, ACADM, IVD, HADH, BCAT2, MUT |
| BLUM RESPONSE TO SALIRASIB DN | KIF20A, HDAC1, ESPL1, HN1, TMPO, PLK1, STMN1, CENPA, CENPF, FBXO5, GAMT, MSH2, TUBB, UBE2C, RNASEH2A, TK1, SLC25A10, PXMP2, BUB1B, CCNA2, KIF4A, CCNB2, TTK, TUBG1, MSH6, CDC20, PAFAH1B3, TPX2, KIF23, CDC25C, POLE2, NEK2, H2AFV, GPSM2, TACC3, SUV39H1, FASN, SLC9A3R1, KIF2C |
| RHEIN ALL GLUCOCORTICOID THERAPY DN | BUB1B, MAD2L1, LTA4H, MLF1IP, STMN1, MRPS33, CCNG1, PSIP1, CCNB2, RACGAP1, APEX1, TTK, ACAT1, TUBB, HADH, ALDH6A1, CPNE3, POLE2, CACYBP, WASF1, ZFAND1, BIRC5 |
| WONG EMBRYONIC STEM CELL CORE | BUB1B, HDAC1, KIF20A, LMNB1, HN1, MAD2L1, CKAP2, PLK1, CCNF, AURKB, MRPL12, CCNA2, CDCA3, KIF4A, CCNB2, GMNN, RACGAP1, APEX1, TTK, CDC20, MSH2, KIF23, HADH, GTSE1, POLE2, NIPSNAP1, NEK2, NT5DC2, BIRC5 |
| LINDGREN BLADDER CANCER CLUSTER 3 UP | CKAP2, TMPO, PLK1, CCNB1, STMN1, CENPA, ALDH9A1, CENPF, KIF4A, CCNB2, RACGAP1, MSH2, KIF23, UBE2C, PXMP4, NEK2, H2AFV, GMCL1, RNASEH2A, TACC3, ERBB2, KIF2C, BIRC5 |
| REACTOME CENTROSOME MATURATION | NEK2, TUBG1, CKAP5, PRKACA, ODF2, TUBB, PLK1, CCNB1, NDE1 |
| REACTOME G2 M TRANSITION | CCNB2, TUBG1, TUBB, CDC25C, PLK1, CCNB1, CKAP5, PRKACA, ODF2, CCNA2, NDE1 |
| LOPEZ MESOTELIOMA SURVIVAL TIME UP | |
| REACTOME CELL CYCLE MITOTIC | |
| NAKAYAMA SOFT TISSUE TUMORS PCA2 UP | |
| NCI CENTROSOME MATURATION | |
| SCIAN CELL CYCLE TARGETS OF TP53 AND TP73 DN | |
| MONTERO THYROID CANCER POOR SURVIVAL UP | CCNB2, NUSAP1, PRC1, UBE2C, ASPM, BIRC5, CENPA |
| BENPORATH CYCLING GENES | |
| RHODES UNDIFFERENTIATED CANCER | CDC20, KIF23, UBE2C, CCNB1, CENPA, H2AFX, CCNA2, KIF2C, BIRC5 |
| KUMAMOTO RESPONSE TO NUTLIN 3A DN | |
| PAL PRMT5 TARGETS UP | |
| HORIUCHI WTAP TARGETS DN | |
| NCI AURORA B PATHWAY | |
| SHEPARD BMYB TARGETS | |
| CORUM RC COMPLEX DURING G2/M-PHASE OF CELL CYCLE | |
| ODONNELL TARGETS OF MYC AND TFRC DN | |
| REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | |
| NCI PLK1 PATHWAY | |
| PRAMOONJAGO SOX4 TARGETS DN | |
| BUYTAERT PHOTODYNAMIC THERAPY STRESS DN | |
| ODONNELL TFRC TARGETS DN | |
| MARKEY RB1 ACUTE LOF DN | |
| MUELLER PLURINET | |
| NCI LOSS OF PROTEINS REQUIRED FOR INTERPHASE MICROTUBULE ORGANIZATION FROM THE CENTROSOME | |
| RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY UP | |
| CORUM CTBP CORE COMPLEX | |
| HOFFMANN LARGE TO SMALL PRE BII LYMPHOCYTE UP | |
| NCI LOSS OF NLP FROM MITOTIC CENTROSOMES | |
| FINETTI BREAST CANCER BASAL VS LUMINAL | |
| NCI RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES | |
| ALCALAY AML BY NPM1 LOCALIZATION DN | |
| YU MYC TARGETS UP | |
| LY AGING MIDDLE DN | |
| REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | |
| KEGG BUTANOATE METABOLISM | |
| CORUM GCN5-TRRAP HISTONE ACETYLTRANSFERASE COMPLEX | |
| CHIANG LIVER CANCER SUBCLASS UNANNOTATED DN | |
| CHIANG LIVER CANCER SUBCLASS PROLIFERATION UP | BUB1B, KIF20A, LMNB1, HN1, CCNB1, CCNA2, CCNB2, RACGAP1, TTK, CDC20, KIF23, UBE2C, WASF1, GPD1L, NEK2, KIF2C, BIRC5, ASPM |
| CORUM BRM-SIN3A COMPLEX | |
| MORI LARGE PRE BII LYMPHOCYTE UP | |
| FINETTI BREAST CANCER KINOME RED | |
| CHANG CYCLING GENES | CCNB2, ASF1B, LMNB1, TACC3, KIF23, CDC25C, UBE2C, CENPA |
| SHEPARD CRUSH AND BURN MUTANT DN | |
| TANG SENESCENCE TP53 TARGETS DN | |
| CORUM CTBP COMPLEX | |
| CORUM RC COMPLEX DURING S-PHASE OF CELL CYCLE | |
| BENPORATH PROLIFERATION | |