| Gene Set | Leading Edge Genes |
|---|
| KEGG OXIDATIVE PHOSPHORYLATION | ATP5C1, SDHB, NDUFA3, ATP5G2, NDUFB8, NDUFA1, NDUFA10, NDUFS8, CYC1, ATP5O, UQCRC1, ATP5A1, NDUFS6, ATP5G1, NDUFS2, NDUFB6, COX8A, NDUFB2, COX7C, ATP5B, NDUFS3, NDUFC1 |
| KEGG PARKINSONS DISEASE | SDHB, NDUFA3, ATP5G2, NDUFB8, PARK7, NDUFA1, NDUFA10, NDUFS8, CYC1, ATP5O, UQCRC1, NDUFS6, NDUFS2, NDUFB6, ATP5B, COX7C, NDUFS3, NDUFC1 |
| KEGG HUNTINGTONS DISEASE | SDHB, NDUFA3, ATP5G2, NDUFB8, GPX1, NDUFA1, NDUFA10, NDUFS8, CYC1, POLR2J, ATP5O, UQCRC1, NDUFS6, AP2B1, NDUFS2, NDUFB6, ATP5B, COX7C, NDUFS3, NDUFC1 |
| KEGG ALZHEIMERS DISEASE | SDHB, CALM3, NDUFA3, ATP5G2, NDUFB8, ADAM10, NDUFA1, NDUFA10, NDUFS8, CYC1, ATP5O, NDUFS6, APH1A, NDUFS2, NDUFB6, ATP5B, COX7C, NDUFS3, NDUFC1 |
| CASORELLI ACUTE PROMYELOCYTIC LEUKEMIA DN | SQLE, HSP90AB1, YBX1, SDHA, TM7SF2, GMPPB, STOM, CYC1, MRPL28, CTNNBL1, NSDHL, UQCRC1, MCM3, TUBB, GP1BB /// SEPT5, TUFM, BCAP31, EBP, CDC45L, ILKAP, PSMB6, RANGAP1, CMAS, COIL, ETFB, ACAT1, INSIG1, NUDT1, ACAT2, HADHA, CDC25C, GLO1, NUP93, MVD, LMAN2, GPSM2, TARDBP, IDI1, HSD17B4, STIP1, KIF2C, MGAT3, XRCC6 |
| ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE UP | IFRD2, ILF2, CSTF2, CETN2, HSP90AB1, COPE, DYNLRB1, DHX29, SDF2L1, SDF2, UFC1, HSPA14, PSMB5, APEX1, MCM3, GMPS, ACP1, SSR2, PIGT, HAX1, GPKOW, COPB2, SURF1, SERPINH1, PAPSS1, OXA1L, RFC4, NEDD8, UFM1, CUL2, PSMB2, NHP2L1, PSMD2, PSMD6, NUDT1, SFRS2, IDH1, TMCO3, APEX2, IDI1, TRAPPC4, MRPL48, TFG, XRCC6 |
| BORCZUK MALIGNANT MESOTHELIOMA UP | SCCPDH, COPS5, ILF2, HSP90AB1, PRPS2, PSMA2, CDK4, RAN, YKT6, NCBP2, PPP4C, AP2S1, MRPL28, DBI, FNTA, EMG1, ATP5A1, NDUFS2, BET1, SLC25A3, SDHB, PSMB6, PARK7, CCNG1, PSMB7, RFC4, PSMD2, DNAJA1, TPX2, NUDT1, GLO1, PGRMC1, H2AFV, DDOST, STIP1 |
| REACTOME CELL CYCLE MITOTIC | KIF20A, PSMC5, SSNA1, CDK5RAP2, CETN2, PSMA2, DBF4, PSMB6, PPP2CA, CDK4, RANGAP1, PSMD11, PSMB7, PSMD4, RFC4, ANAPC5, RFC5, CENPF, NUP85, MNAT1, PSMD14, PSMB2, PSMD2, MCM3, PSMB5, PSMD6, TUBB, PSMD12, PSMB3, KNTC1, KIF2C |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 14 | SERPINH1, APEX1, PSMB5, PSMD6, HDLBP, SMYD2, SSR2, CDK4, PDIA4, SNRPD3, PREP, SEC61A1, LMAN2, BANF1 |
| REACTOME S PHASE | PSMC5, PSMA2, PSMB6, PSMC3, CDK4, PSMD11, PSMB7, RFC4, PSMD4, CCNA2, RFC5, MNAT1, PSMB2, PSMD2, PSMB5, MCM3, PSMD6, PSMD3, PSMD12, PSMB3 |
| MISSIAGLIA REGULATED BY METHYLATION DN | ITGB4, GMPS, ACAT2, STMN1, CBARA1, NDUFS3, RFC5, KNTC1, EBP |
| REACTOME CELL CYCLE CHECKPOINTS | PSMC5, PSMA2, PSMB6, PSMD11, PSMB7, RFC4, PSMD4, ANAPC5, RFC5, PSMD14, PSMB2, PSMB5, MCM3, PSMD2, PSMD6, PSMD3, PSMD12, CDC25C, PSMB3 |
| BIDUS METASTASIS UP | SQLE, YBX1, DBF4, PPP2CA, BCL7A, CENPA, RRM1, CKAP5, PBK, NCBP2, RFC4, HMGB3, PCBP1, RFC5, CENPF, RAE1, TPX2, SFRS2, TARDBP |
| FOURNIER ACINAR DEVELOPMENT LATE 2 | SQLE, RAI14, POLE3, LDLR, CLPB, CDC45L, UCHL5, PTPLAD1, COL4A2, NUP85, CDCA3, PSMB2, MCM3, TUBG1, PITRM1, TIPIN, PRDX3, H2AFV, IDI1, KIF2C, NT5DC2, HMBS |
| REACTOME SYNTHESIS OF DNA | PSMC5, PSMA2, PSMB6, PSMC3, PSMD11, PSMB7, PSMD4, RFC4, CCNA2, RFC5, PSMB2, PSMB5, MCM3, PSMD2, PSMD6, PSMD12, PSMB3 |
| REACTOME DNA REPLICATION PRE INITIATION | PSMC5, PSMA2, PSMB6, DBF4, PSMC3, PSMD11, PSMB7, PSMD4, PSMD14, PSMB2, PSMB5, MCM3, PSMD2, PSMD6, PSMD3, PSMD12, PSMB3 |
| KOBAYASHI EGFR SIGNALING 24HR DN | CDC45L, RANGAP1, PBK, HMMR, RFC5, CDCA3, HSPA14, EZH2, MCM3, TUBG1, TUBB, TPX2, TIPIN, TUBB2C, GPSM2, POLR3K, PRC1, TUBB6, KIF2C |
| WHITEFORD PEDIATRIC CANCER MARKERS | RFC4, ILF2, NUDT1, CENPF, CDK4, STMN1 |
| PELLICCIOTTA HDAC IN ANTIGEN PRESENTATION UP | PSMD2, PSMD6, COPE, PDIA4, YIPF5, PSMB7, PSMD4, PSMB3, TRAPPC4, COPZ1, COPB2, BCAP31 |
| SOTIRIOU BREAST CANCER GRADE 1 VS 3 UP | KIF20A, CDC45L, STMN1, MRPL15, HMMR, CDCA3, EZH2, MCM3, CDC20, GMPS, NUDT1, PSMD12, PFDN6, NUP93, TACC3, PRC1, STIP1 |
| KEGG STEROID BIOSYNTHESIS | |
| LI WILMS TUMOR VS FETAL KIDNEY 1 DN | |
| MITSIADES RESPONSE TO APLIDIN DN | |
| RAMALHO STEMNESS UP | |
| MORI IMMATURE B LYMPHOCYTE DN | |
| REACTOME TELOMERE MAINTENANCE | |
| MOLENAAR TARGETS OF CCND1 AND CDK4 DN | |
| ZHAN MULTIPLE MYELOMA PR UP | |
| SCHUHMACHER MYC TARGETS UP | |
| REACTOME INTEGRATION OF ENERGY METABOLISM | |
| MOREAUX B LYMPHOCYTE MATURATION BY TACI DN | |
| REACTOME GLOBAL GENOMIC NER | |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 10 | |
| REACTOME DNA STRAND ELONGATION | |
| TOYOTA TARGETS OF MIR34B AND MIR34C | |
| CORUM 39S RIBOSOMAL SUBUNIT MITOCHONDRIAL | MRPL34, MRPL16, MRPL46, MRPL28, MRPL35 |
| DAIRKEE TERT TARGETS UP | |
| MANALO HYPOXIA DN | |
| MOOTHA FFA OXYDATION | |
| REACTOME EXTENSION OF TELOMERES | |
| RICKMAN TUMOR DIFFERENTIATED MODERATELY VS POORLY DN | |
| RICKMAN METASTASIS UP | |
| REN BOUND BY E2F | |
| REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | |
| WEST ADRENOCORTICAL TUMOR UP | |
| CROONQUIST NRAS SIGNALING DN | |
| CORUM 55S RIBOSOME MITOCHONDRIAL | MRPS7, MRPS16, MRPS12, MRPS11, MRPL35, DAP3, MRPL15, MRPL16, MRPL34, MRPL46, MRPL28 |
| NCI ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | |
| WEI MYCN TARGETS WITH E BOX | |
| REACTOME DNA REPAIR | |
| ZHANG RESPONSE TO CANTHARIDIN DN | |
| ACEVEDO NORMAL TISSUE ADJACENT TO LIVER TUMOR DN | |
| CORUM 28S RIBOSOMAL SUBUNIT MITOCHONDRIAL | |
| RHODES CANCER META SIGNATURE | |
| SHEDDEN LUNG CANCER POOR SURVIVAL A6 | |
| KAUFFMANN DNA REPAIR GENES | |
| AMUNDSON GAMMA RADIATION RESPONSE | |
| RICKMAN TUMOR DIFFERENTIATED MODERATELY VS POORLY UP | |
| FUJII YBX1 TARGETS DN | |
| REACTOME G2 M CHECKPOINTS | |