| Gene Set | Leading Edge Genes |
|---|
| CORUM RESPIRATORY CHAIN COMPLEX I LAMBDA SUBUNIT MITOCHONDRIAL | NDUFS6, NDUFS7, NDUFS3, NDUFS8, NDUFA5, NDUFA2 |
| WONG EMBRYONIC STEM CELL CORE | HDAC1, KIF20A, STOML2, NCBP2, ADSL, RUVBL1, RPA3, PPM1G, CCNA2, KIF4A, ATP5O, NDUFB7, RPP40, PUS1, ACAD8, HADH, CCT5, DHX9, POP7, KIF22, MRPL16, BANF1, ZNF22, LSM5, NT5DC2, BIRC5 |
| PUJANA CHEK2 PCC NETWORK | HDAC1, RBBP4, POLE3, PRKRIR, TAF11, C1QBP, ZWINT, TMPO, RAN, SLBP, NCBP2, ADSL, CPSF4, ANAPC5, ORC5L, TOPBP1, ICT1, ATP5O, EXOSC8, C1D, FRG1, TMEM106C, CPT1A, POLR2H, COPS3, NUP88, SSRP1, ZNF22, LMNB2, BUB3, LSM5, CTCF, PAICS, LSM7, MPHOSPH6, UBE2G1, TFAM, RUVBL1, RPA3, NUTF2, FGF8, CCNA2, MNAT1, PRKRA, CCT5, DHX9 |
| ZHANG BREAST CANCER PROGENITORS UP | CTCF, CASP8AP2, PAICS, TMPO, LSM7, MRPS33, TRRAP, RPA3, CCNA2, TOPBP1, ORC5L, C1D, ASXL1, PHB2, LRRC40, LSM5 |
| REACTOME METABOLISM OF RNA | NUP88, EXOSC8, NUP133, NUP37, DCPS, LSM5, EXOSC2 |
| SCHLOSSER MYC TARGETS REPRESSED BY SERUM | EXOSC8, POLE3, CCT5, DHX9, NDUFB6, RAN, FBXO9, UBE2G1, TFAM, SERBP1, SLC39A6, BUB3, CHERP |
| NCI FORMATION OF HIV 1 ELONGATION COMPLEX CONTAINING HIV 1 TAT | |
| REACTOME CELL CYCLE MITOTIC | KIF18A, NUP133, ODF2, RPA3, ANAPC5, NUP37, DCTN1, MNAT1 |
| NCI TAT MEDIATED ELONGATION OF THE HIV 1 TRANSCRIPT | |
| REACTOME MRNA 3 END PROCESSING | |
| REACTOME LATE PHASE OF HIV LIFE CYCLE | RDBP, TAF11, TCEB2, TAF10, RAN, NCBP2, NUP133, MNAT1, POLR2J, POLR2D, POLR2F, RAE1, NUP37, POLR2H, SSRP1, NUP88, POLR2C |
| REACTOME RNA POL II CTD PHOSPHORYLATION AND INTERACTION WITH CE | |
| NCI TRANSCRIPTION COUPLED NER TC NER | POLR2E, POLR2B, POLR2D, POLR2F, ERCC5, POLR2J |
| REACTOME NUCLEOTIDE EXCISION REPAIR | POLR2E, POLR2D, POLR2F, RFC2, POLR2H, POLR2B, RPA3, POLR2C, ERCC5, POLR2J, MNAT1 |
| NCI GLOBAL GENOMIC NER GG NER | |
| REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT | POLR2H, POLR2E, POLR2B, RDBP, NCBP2, POLR2D, POLR2F, POLR2C, POLR2J |
| CORUM DDB2 COMPLEX | |
| NCI ELONGATION OF INTRON CONTAINING TRANSCRIPTS AND CO TRANSCRIPTIONAL MRNA SPLICING | POLR2E, POLR2D, POLR2F, POLR2H, POLR2B, NCBP2, POLR2C, POLR2J, MNAT1 |
| CORUM C COMPLEX SPLICEOSOME | PNN, MAGOH, DDX41, FRG1, SFRS1, SNRPD3, PRPF19, PRPF4B, RBM8A, SNRPD2, AQR, LSM2, SNRPB2 |
| CORUM RNA POLYMERASE II CORE COMPLEX | |
| NCI VIRAL MESSENGER RNA SYNTHESIS | |
| REACTOME GLOBAL GENOMIC NER | MNAT1 |
| NCI FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX | POLR2E, POLR2B, POLR2D, POLR2F, ERCC5, POLR2J |
| REACTOME MICRORNA BIOGENESIS | |
| CORUM BRCA1-CORE RNA POLYMERASE II COMPLEX | |
| NCI FORMATION OF THE HIV 1 EARLY ELONGATION COMPLEX | POLR2E, RDBP, POLR2D, POLR2F, POLR2H, NCBP2, POLR2C, POLR2J, MNAT1 |
| LEE METASTASIS AND RNA PROCESSING UP | |
| NCI ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT | POLR2E, POLR2B, RDBP, NCBP2, POLR2D, POLR2F, POLR2J |
| REACTOME TRANSCRIPTION COUPLED NER | POLR2E, POLR2D, POLR2F, RFC2, POLR2H, RPA3, POLR2C, ERCC5, POLR2J, MNAT1 |
| NCI MRNA CAPPING | |
| KEGG SPLICEOSOME | |
| REACTOME MRNA SPLICING MINOR PATHWAY | POLR2E, PRPF8, POLR2D, POLR2F, SF3B5, POLR2H, SNRPD3, POLR2B, POLR2K, NCBP2, POLR2C, LSM2, POLR2J |
| KEGG RNA POLYMERASE | POLR2H, POLR2E, POLR2B, POLR2D, POLR2K, POLR2F, POLR2C, POLR2J |
| NCI PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | |
| REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | |
| NCI FORMATION OF THE EARLY ELONGATION COMPLEX | POLR2E, RDBP, POLR2D, POLR2F, POLR2H, NCBP2, POLR2C, POLR2J, MNAT1 |
| NCI DUAL INCISION REACTION IN GG NER | |
| CHIANG LIVER CANCER SUBCLASS UNANNOTATED DN | |
| ZHONG RESPONSE TO AZACITIDINE AND TSA DN | CIRBP, GOLPH3L, RBM8A, CCNA2, ICT1, LSM7 |
| NCI CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION | |
| KEGG PYRIMIDINE METABOLISM | |
| REACTOME VIRAL MESSENGER RNA SYNTHESIS | |
| NCI FORMATION OF INCISION COMPLEX IN GG NER | |
| REACTOME HIV1 TRANSCRIPTION ELONGATION | |
| ZHANG RESPONSE TO CANTHARIDIN DN | |
| REACTOME DNA REPAIR | POLR2H, POLD2, MPG, XRCC1, RPA3, MNAT1, FANCG |
| REACTOME DUAL INCISION REACTION IN TC NER | POLR2E, POLR2B, POLR2D, POLR2F, ERCC5, POLR2J |
| CORUM SPLICEOSOME | |
| MOREAUX MULTIPLE MYELOMA BY TACI DN | ZCCHC10, C1QBP, LRRC40, BUB3, ORC5L, MRPS12, LSM5 |
| RHODES CANCER META SIGNATURE | |
| NCI HIV 1 TRANSCRIPTION ELONGATION | POLR2E, RDBP, POLR2D, POLR2F, POLR2H, NCBP2, POLR2C, POLR2J, MNAT1 |
| REACTOME HIV LIFE CYCLE | RDBP, TAF11, TCEB2, TAF10, RAN, NCBP2, NUP133, MNAT1, POLR2J, POLR2D, POLR2F, RAE1, NUP37, POLR2H, SSRP1, NUP88, BANF1, POLR2C |
| REACTOME DUAL INCISION REACTION IN GG NER | |
| NCI DUAL INCISION REACTION IN TC NER | POLR2E, POLR2B, POLR2D, POLR2F, ERCC5, POLR2J |
| NCI MICRORNA MIRNA BIOGENESIS | |
| REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX | POLR2E, RDBP, POLR2D, POLR2F, POLR2H, POLR2B, NCBP2, POLR2C, POLR2J, MNAT1, SUPT5H |
| NCI MRNA 3 END PROCESSING | |
| REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | MAGOH, UPF3B, POLR2L, SLBP, NCBP2, NUP133, NUDT21, POLR2J, SNRPB2, POLR2D, POLR2F, CPSF1, NUP37, SF3B5, DHX9, POLR2H, NUP88, RBM8A, SNRPD2, POLR2C |
| NCI MRNA SPLICING MINOR PATHWAY | POLR2L, SNRPD3, WDR57, POLR2B, POLR2K, NCBP2, POLR2J, POLR2E, PRPF8, POLR2D, POLR2F, SFRS1, SF3B5, POLR2H, SNRPD2, POLR2C, LSM2 |
| KEGG NUCLEOTIDE EXCISION REPAIR | POLE3, RPA3, MNAT1 |