| Gene Set | Leading Edge Genes |
|---|---|
| RHEIN ALL GLUCOCORTICOID THERAPY DN | BUB1B, TRMT5, INTS8, KIF11, MAD2L1, ATP5C1, ELAVL1, HPRT1, STMN1, SMC1A, SCP2, RRM1, PCCA, NDUFB5, SHCBP1, ACADM, PSIP1, ECT2, RACGAP1, TTK, ACAT1, GMPS, HADH, POLE2, TMEM135, FANCL, CFDP1 |
| PUJANA CHEK2 PCC NETWORK | AP3S1, RFC3, POLE3, SEPHS1, STMN1, CENPA, RFC5, CENPF, CNOT1, MCM3, METAP1, GMPS, CDC23, GSR, NUP88, DDX46, PPP2R5C, KNTC1, CTR9, WDR68, BUB1B, LMNB1, CENPI, CENPC1, CAD, AGL, KIF11, MAD2L1, HPRT1, SMC1A, FOXM1, CSE1L, RRM1, RANBP9, PSIP1, TTK, MSH6, PARP1, TPX2, FADS1, POLE2, MRE11A, KIF2C, PRPSAP2 |
| ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE UP | AP3S1, NUDT2, ELOVL6, HPRT1, FARS2, MIF4GD, HTATSF1, MCFD2, NDUFB5, UCHL5, HSPA14, SLC9A6, MCM3, PPOX, METAP1, EIF2B1, MSH6, GMPS, PARP1, IDH1, ALG14, DDX46, TBCE, XRCC6BP1, TSPAN14, UBE4B, CTR9, SURF1 |
| TIEN INTESTINE PROBIOTICS 24HR UP | BUB1B, KIF20A, PDHB, KIF11, CENPI, MAD2L1, HPRT1, CENPA, FOXM1, TRIAP1, HTATSF1, SHCBP1, LMAN2L, TOPBP1, CENPF, HSPA14, ABCD3, DERA, SLC9A6, SC4MOL, RACGAP1, MCM3, MSH6, CYB5B, POLE2, SPAST, DDX46, DAB2, QDPR |
| WONG EMBRYONIC STEM CELL CORE | KIF20A, LMNB1, MAD2L1, ELOVL6, CKAP2, KRAS, IPO9, CDCA3, HSPA14, KIF4A, MCM3, RACGAP1, PARP1, ACAD8, HADH, POLE2, NIPSNAP1, THOC3, NEK2 |
| MISSIAGLIA REGULATED BY METHYLATION DN | PSIP1, BUB1B, MSH6, CAD, LMNB1, CDC25C, STMN1, CBARA1, FOXM1, RRM1, NDUFS3, RFC5, KNTC1 |
| FOURNIER ACINAR DEVELOPMENT LATE 2 | RFC3, CAD, POLE3, ELOVL6, DNM1L, MUS81, CENPA, FOXM1, CSE1L, TMEM48, UCHL5, CDCA3, KIF4A, MCM3, RACGAP1, MSH6, VCL, NCAPG2, ELK3 |
| FUJII YBX1 TARGETS DN | KIF4A, MCM3, LMNB1, MAD2L1, CENPK, CDC25C, HADH, POLE2, FOXM1, SHCBP1, RFC5, SSR1, FIGNL1, UBE4B |
| WILCOX PRESPONSE TO ROGESTERONE UP | |
| REACTOME CELL CYCLE MITOTIC | BUB1B, KIF20A, RFC3, CDC16, CENPC1, CENPI, CDK5RAP2, MAD2L1, CENPA, SMC1A, TSGA14, MAPRE1, RFC5, CENPF, NUP85, MCM3, TUBG1, CENPK, PPP2R5A, CDC23, CDC25C, POLE2, ANAPC1, NEK2, KNTC1, PPP2R5C, KIF2C, NDE1 |
| FLECHNER BIOPSY KIDNEY TRANSPLANT REJECTED VS OK DN | |
| BORCZUK MALIGNANT MESOTHELIOMA UP | |
| KEGG PEROXISOME | |
| LI WILMS TUMOR VS FETAL KIDNEY 1 DN | |
| MITSIADES RESPONSE TO APLIDIN DN | |
| REACTOME CELL CYCLE CHECKPOINTS | |
| MORI IMMATURE B LYMPHOCYTE DN | |
| REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | |
| WAKASUGI HAVE ZNF143 BINDING SITES | |
| MOLENAAR TARGETS OF CCND1 AND CDK4 DN | |
| ZHAN MULTIPLE MYELOMA PR UP | |
| REACTOME PEROXISOMAL LIPID METABOLISM | |
| ODONNELL TFRC TARGETS DN | |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | |
| TOYOTA TARGETS OF MIR34B AND MIR34C | |
| MANALO HYPOXIA DN | |
| KEGG DNA REPLICATION | |
| RICKMAN METASTASIS UP | |
| BIDUS METASTASIS UP | |
| WEST ADRENOCORTICAL TUMOR UP | |
| KEGG BIOSYNTHESIS OF UNSATURATED FATTY ACIDS | |
| KOBAYASHI EGFR SIGNALING 24HR DN | |
| KEGG MISMATCH REPAIR | |
| EGUCHI CELL CYCLE RB1 TARGETS | |
| CAIRO HEPATOBLASTOMA CLASSES UP | |
| REACTOME DNA REPAIR | |
| SHEDDEN LUNG CANCER POOR SURVIVAL A6 | |
| REACTOME DNA REPLICATION PRE INITIATION | |
| KAUFFMANN DNA REPAIR GENES |
| Color legend | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| q-value | -1 | -0.2 | -0.05 | -0.01 | -0.001 | -0.0001 | |||||
| Color | |||||||||||
| helicobacter pylori kx2 npgec | streptococcus pneumoniae d39 | helicobacter pylori kx1 npgec | escherichia coli | ehrlichia chaffeensis liberty | GeneSet Name |
|---|---|---|---|---|---|
| -0.00435 | -0.09494 | -0.00293 | -0.01385 | -0.08669 | RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN |
| -0.00736 | -0.01854 | -0.00673 | -0.01673 | -0.17936 | PUJANA_CHEK2_PCC_NETWORK |
| -0.00489 | -0.03975 | -0.00733 | -0.03431 | -0.17557 | ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP |
| -0.00160 | -0.00708 | -0.00057 | -0.08017 | -0.01033 | TIEN_INTESTINE_PROBIOTICS_24HR_UP |
| -0.01048 | -0.09472 | -0.00353 | -0.00075 | -0.00681 | WONG_EMBRYONIC_STEM_CELL_CORE |
| -0.00300 | -0.11602 | -0.00244 | -0.00002 | -0.08244 | MISSIAGLIA_REGULATED_BY_METHYLATION_DN |
| -0.00795 | -0.14008 | -0.00300 | -0.09170 | -0.02119 | FOURNIER_ACINAR_DEVELOPMENT_LATE_2 |
| -0.01337 | -0.00733 | -0.00344 | -0.00002 | -0.05731 | FUJII_YBX1_TARGETS_DN |
| -0.07181 | -0.14164 | -0.02611 | -0.01543 | -0.16956 | WILCOX_PRESPONSE_TO_ROGESTERONE_UP |
| -0.00105 | -0.03832 | -0.00054 | -0.00008 | -0.14637 | REACTOME_CELL_CYCLE_MITOTIC |
| -0.01843 | -0.09827 | -0.00698 | -0.10980 | -0.02290 | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN |
| -0.00017 | -0.01909 | -0.00038 | -0.14538 | -0.08517 | BORCZUK_MALIGNANT_MESOTHELIOMA_UP |
| -0.04060 | -0.08208 | -0.01373 | -0.00379 | -0.00008 | KEGG_PEROXISOME |
| -0.02224 | -0.03326 | -0.01328 | -0.00499 | -0.12543 | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN |
| -0.00683 | -0.00376 | -0.00925 | -0.00002 | -0.08816 | MITSIADES_RESPONSE_TO_APLIDIN_DN |
| -0.00003 | -0.18352 | -0.00086 | -0.03627 | -0.05832 | REACTOME_CELL_CYCLE_CHECKPOINTS |
| -0.02413 | -0.00708 | -0.00202 | -0.00005 | -0.07682 | MORI_IMMATURE_B_LYMPHOCYTE_DN |
| -0.01157 | -0.18461 | -0.02227 | -0.04835 | -0.09717 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM |
| -0.13870 | -0.05418 | -0.04323 | -0.00048 | -0.09953 | WAKASUGI_HAVE_ZNF143_BINDING_SITES |
| -0.00059 | -0.02179 | -0.01373 | -0.00017 | -0.08292 | MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_DN |
| -0.06073 | -0.06787 | -0.06738 | -0.00002 | -0.12250 | ZHAN_MULTIPLE_MYELOMA_PR_UP |
| -0.00494 | -0.12205 | -0.01303 | -0.02116 | -0.02794 | REACTOME_PEROXISOMAL_LIPID_METABOLISM |
| -0.01570 | -0.08433 | -0.00798 | -0.00011 | -0.11168 | ODONNELL_TFRC_TARGETS_DN |
| -0.05828 | -0.08443 | -0.02063 | -0.04179 | -0.13498 | LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN |
| -0.01704 | -0.03505 | -0.02530 | -0.00006 | -0.17694 | TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C |
| -0.02679 | -0.02142 | -0.05884 | -0.00285 | -0.00680 | MANALO_HYPOXIA_DN |
| -0.05497 | -0.18309 | -0.00933 | -0.00035 | -0.05540 | KEGG_DNA_REPLICATION |
| -0.09744 | -0.03433 | -0.05493 | -0.01546 | -0.17550 | RICKMAN_METASTASIS_UP |
| -0.00955 | -0.00363 | -0.00728 | -0.00302 | -0.12771 | BIDUS_METASTASIS_UP |
| -0.00769 | -0.07686 | -0.00298 | -0.10340 | -0.00510 | WEST_ADRENOCORTICAL_TUMOR_UP |
| -0.05304 | -0.15504 | -0.05067 | -0.15291 | -0.00005 | KEGG_BIOSYNTHESIS_OF_UNSATURATED_FATTY_ACIDS |
| -0.04230 | -0.07071 | -0.00610 | -0.00476 | -0.16719 | KOBAYASHI_EGFR_SIGNALING_24HR_DN |
| -0.02889 | -0.16509 | -0.06315 | -0.00033 | -0.05781 | KEGG_MISMATCH_REPAIR |
| -0.13000 | -0.01971 | -0.02187 | -0.00006 | -0.08972 | EGUCHI_CELL_CYCLE_RB1_TARGETS |
| -0.02501 | -0.10890 | -0.01507 | -0.00621 | -0.04425 | CAIRO_HEPATOBLASTOMA_CLASSES_UP |
| -0.06785 | -0.18550 | -0.04418 | -0.00022 | -0.10973 | REACTOME_DNA_REPAIR |
| -0.02761 | -0.07798 | -0.03282 | -0.00959 | -0.14253 | SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 |
| -0.00061 | -0.14167 | -0.00239 | -0.19797 | -0.19897 | REACTOME_DNA_REPLICATION_PRE_INITIATION |
| -0.09101 | -0.01600 | -0.06811 | -0.00003 | -0.08733 | KAUFFMANN_DNA_REPAIR_GENES |