| Gene Set | Leading Edge Genes |
|---|
| NUYTTEN NIPP1 TARGETS DN | PPP1CB, PLEKHF2, SEC23A, HMGCR, PPP2CB, ASPH, TMPO, RNF138, PRKAR1A, CXCR7, SMU1, BMPR2, PCGF3, TSPYL1, ABCA1, OSBPL3, SP3, NOTCH1, UGDH, VCL, MAN2A1, ACSL3, PKD2, RNF11, PPP2R1B, CUL3, YME1L1, LRRC14, ROCK2, EPAS1, GOLT1B, PRR11, PYGB, SMC1A, SLC16A1, MARCH6, RANBP9, BTBD3, ADAM9, RNF13, MBNL2, RAP2C, HIPK1, FBXO21, DNAJA1, SERINC1, PDCD10, WDR37, PJA2, RBM12, TBL1XR1, PRPS2, PAK2, FZD4, MTMR9, RB1CC1, NUDT4, BAG5, TSGA14, JMJD4, MKNK2, ATP6V1A, CAV2, UBE2W, TMED7, GOLGA2, F2R, EXOSC2, SLC25A24, CAV1, RAI14, CAPZA2, ISYNA1, GNA11, SPTLC2, CMTM6, CREBL2, FNBP1, CASP3, CCND1, FSCN1, PHF15, PIR, NF2, GOLGA1, SGPP1, CRK, ECT2, WSB2, RPS6KB1, TULP4, LBR, SETD8, HEXIM1, SYNJ2BP, INHBB, CCDC91, ZMPSTE24, SDC1 |
| FLECHNER BIOPSY KIDNEY TRANSPLANT OK VS DONOR UP | ABI1, SEC23A, PPP2CB, ACADSB, PRKAR1A, HSPE1, STRN3, SH3BGRL, DEK, ARPC5, SP3, COL1A2, AZIN1, ACSL3, NPTN, MYO1B, COL4A1, CNIH, STAT3, PPP2R5C, PALLD, NCOA3, CD2AP, TRIM44, AGL, CBR4, GLS, AMD1, SCP2, TMEM123, BTBD3, PPP1R2, PTP4A2, ADD3, TOR1AIP1, C1S, DNAJA1, STAT1, SERINC1, ID1, PRKRA, MYH9, ATF2, PJA2, DYNLL1, RNF6, RB1, DDX5, FNBP1L, SEC22B, PFTK1, RECQL, CDC42BPA, SEC24B, PDLIM5, RPS6KA3, ATP6V1A, SMAD5, AHCYL1, ETF1, TNPO1, FHL1, ASF1A, AHR, CREBL2, COPS2, NEK7, OAT, ZMPSTE24, ARHGEF18, QDPR, ELOVL5 |
| ENK UV RESPONSE KERATINOCYTE DN | FKBP5, SEC23A, SLC31A1, ABCE1, HSPD1, ACADSB, PRKAR1A, PRKCI, SLBP, JAG2, KRAS, HSPE1, STRN3, AASDHPPT, MECP2, PCGF3, DEK, IFIT1, ARHGEF7, UGDH, GAS2L1, MAN2A1, WASF1, AZIN1, ACSL3, PKD2, NPTN, PRPF4B, YME1L1, RBM9, ROCK2, CTCF, NCOA3, CCDC6, CD2AP, TRIM44, GNAQ, AGL, DDX42, SMC1A, SLC16A1, RNF13, PTP4A2, SRF, DNAJA1, DUSP5, MYO10, ID1, RDX, FZD6, CYP51A1, DLG5, USP1, TROVE2, UMPS, BCAR3, SFRS11, MARCH7, ATP2C1, SEMA3C, RB1, RTCD1, BMI1, SYPL1, PFTK1, COL16A1, NDUFS1, SEC24B, TOP2A, WWTR1, ATP6V1A, TNC, RCBTB2, RAB14, TPR, STK3, POLS, AKAP11, ZNF148, TRIM23, IPO7, PSMD5, GOT1, PAICS, COPS2, SMARCA2, MCM3AP, IGSF3, UPF3A, ACADM, ACTR2, USP14, GOSR1, FMR1, PIK3R3, LBR, PSPH, MBNL1, PURA, CXADR, RBM8A, DDX17, TPST2, ELOVL5, ZNF638, ZFR |
| SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN DN | POLE3, IDS, HPCAL1, SFRS6, BCL2L2, ARPC5, SPAG9, PRPF18, GTF2B, ARHGEF7, MAN2A1, PITPNA, AZIN1, NPTN, GMCL1, LGMN, CNIH, YME1L1, STAT3, ROD1, CCDC6, TRIM44, RHOB, GEMIN4, DCTN4, ARL5A, SCP2, LMAN1, LAP3, USP8, PPP1R2, GRK5, RNF13, CUL4B, E2F6, TRAM1, KIF5B, DNAJA1, PDCD10, EIF2AK3, HADHA, USP1, MRPS35, TTC3, ALDH3A2, SNAPC3, ASAH1, SPTLC1, PDLIM5, SEC24B, RPS6KA3, DNAJC15, RCBTB2, CD164, GARS, ETF1, OXSR1, BRCC3, XBP1, TRAM2, ZNF24, IPO7, EXOC5, GNB1, CREBL2, PCYT1A, MCM3AP, GOLGA1, CRK, TXNRD1, FMR1, KLF6, PSPH, RNF4, CCNC, SKAP2 |
| CREIGHTON ENDOCRINE THERAPY RESISTANCE 5 | PPP1CB, PLEKHF2, SC5DL, AACS, PPP2CB, ACADSB, HSPA2, SH3BP4, SAMD4A, FZD4, APOLD1, NUDT4, CXCR7, KRAS, SEC22B, STRN3, SH3BGRL, AP1G1, SLC25A16, CAB39, IKBKB, LIMK2, UGDH, GALNT7, TMEM135, PKD2, EHD1, RNF11, MYO1B, TRAM2, EFNB2, IL1R1, SYNJ2, CCNE1, GLTP, AHR, MTMR12, B3GNT2, STK38L, PCYT1A, FNBP1, INPP5A, GOLPH3, PTPLAD1, CD55, MBNL2, WSB2, PIK3R3, PDZD2, MBNL1, SOCS6, MYH9, RAB27B, WDR37, INHBB, STX12, PMP22, TWSG1, SDC1 |
| REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | BCKDHB, HIBADH, IVD, ACADSB, ALDH6A1, BCAT1 |
| SHEN SMARCA2 TARGETS UP | ABI1, TRAK2, ARID4B, PRKAR1A, IDS, NAB1, SETX, OSTM1, DLG1, FBXO3, STAG1, AASDHPPT, MECP2, DEK, MAP4K5, SP3, DDX1, CAND1, SLC30A5, NPTN, SEPT2, RNF38, PPP2R5C, PREPL, CTCF, GNAQ, DCTN4, SMC1A, EED, BTBD3, SEC63, PPP1R2, SEPT10, PCMTD2, CUL4B, TOR1AIP1, HIPK1, SERINC1, PRKRA, HMG20A, PTPN11, TSN, PJA2, USP1, TROVE2, TWSG1, TUBGCP3, ANGEL2, MARCH7, RB1, SS18, SPTLC1, SEC24B, SEC23IP, NUMB, RAB14, RMND5A, AKAP11, TMED7, TMEM135, RAB4A, TNPO1, ACVR1, ZDHHC6, SNX5, TLK1, SMAP1, RAB23, CAPZA2, PDHB, SENP6, UPF3B, COPS2, UPF3A, SERINC3, FMR1, SOCS6, PURA, PCNP, NEK7, NCKAP1, ZDHHC17, PKN2 |
| SCHLOSSER MYC TARGETS AND SERUM RESPONSE UP | PTDSS1, GEMIN4, SFRS2, AMD1, SLC1A5, GRPEL1, SLC7A5, LMNB2 |
| MILI PSEUDOPODIA HAPTOTAXIS UP | DPP8, PRPF40A, CLOCK, RNF138, DNM1L, TRAPPC2, IFT74, KRAS, CUGBP2, SH3BGRL, AASDHPPT, DEK, BTBD1, KRR1, RBM7, DDX1, ASNSD1, CUL3, YME1L1, CPSF6, PALLD, TRIM44, CD2AP, ARL5A, HIF1A, SCP2, MTMR6, INTS6, GOLPH3, PTP4A2, CUL4B, MBNL2, YTHDF2, KIF5B, DNAJA1, GULP1, PDCD10, ATF2, PJA2, NXT2, KPNA3, ACSL4, TROVE2, SFRS11, RNF6, PPP3CA, SFRS3, PPP1R7, DDX5, LIMS1, FNBP1L, DIXDC1, SACM1L, PDSS1, MAPK8, VPS4B, DNAJC15, AP4S1, YTHDF3, VCPIP1, SNAP23, NAT12, SERPINB9, SNX5, WDR26, CAPZA2, COPS2, BHLHB9, DYNC1LI2, ACTR2, IFIT2, PSIP1, MBNL1, SMCHD1, CCNE2, SYNJ2BP, PCNP, RAB8B, ARMC1, CCNC, CDV3, ARMCX3, ZFR |
| CAFFAREL RESPONSE TO THC DN | CYP51A1, DNAJA1, SFRS3, HSPA2 |
| CHARAFE BREAST CANCER LUMINAL VS BASAL DN | |
| MARTORIATI MDM4 TARGETS FETAL LIVER DN | |
| MONNIER POSTRADIATION TUMOR ESCAPE UP | |
| NCI COLLAGEN ADHESION VIA ALPHA 2 BETA 1 GLYCOPROTEIN | |
| NCI NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | |
| BORCZUK MALIGNANT MESOTHELIOMA UP | |
| BOYAULT LIVER CANCER SUBCLASS G123 UP | |
| GINESTIER BREAST CANCER ZNF217 AMPLIFIED UP | |
| MILI PSEUDOPODIA CHEMOTAXIS UP | |
| NIKOLSKY BREAST CANCER 6P24 P22 AMPLICON | |
| BROWNE HCMV INFECTION 20HR UP | |
| DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP | |
| RODRIGUES THYROID CARCINOMA ANAPLASTIC UP | |
| LINDGREN BLADDER CANCER WITH LOH IN CHR9Q | |
| SESTO RESPONSE TO UV C5 | |
| RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED DN | |
| ST INTERFERON GAMMA PATHWAY | |
| AMIT EGF RESPONSE 480 HELA | |
| ZHAN EARLY DIFFERENTIATION GENES DN | |
| RIGGINS TAMOXIFEN RESISTANCE DN | |
| RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED UP | |
| MAYBURD RESPONSE TO L663536 DN | |
| KEGG TGF BETA SIGNALING PATHWAY | |
| NCI RETINOIC ACID PATHWAY | |
| DOUGLAS BMI1 TARGETS DN | |
| UDAYAKUMAR MED1 TARGETS UP | |
| NCI TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS | |
| WANG LMO4 TARGETS DN | |
| AMIT EGF RESPONSE 240 MCF10A | |
| DE YY1 TARGETS DN | |
| SCHLOSSER MYC TARGETS REPRESSED BY SERUM | |
| MARTINEZ RESPONSE TO TRABECTEDIN DN | |
| SCHLOSSER SERUM RESPONSE DN | |
| KEGG ACUTE MYELOID LEUKEMIA | |
| RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY DN | |
| GEORGES TARGETS OF MIR192 AND MIR215 | |
| AMIT SERUM RESPONSE 240 MCF10A | |
| SENGUPTA NASOPHARYNGEAL CARCINOMA UP | |
| REACTOME MRNA 3 END PROCESSING | |
| VERRECCHIA RESPONSE TO TGFB1 C1 | |
| RAMALHO STEMNESS UP | |
| GENTILE RESPONSE CLUSTER D3 | |
| GEORGES CELL CYCLE MIR192 TARGETS | |
| SEIDEN ONCOGENESIS BY MET | |
| CORUM ITGA2-ITGB1-COL6A3 COMPLEX | |
| DING LUNG CANCER EXPRESSION BY COPY NUMBER | |
| ELVIDGE HIF2A TARGETS UP | |
| HENDRICKS SMARCA4 TARGETS DN | |
| ELVIDGE HYPOXIA DN | |
| NCI LYMPHANGIOGENESIS PATHWAY | |
| WANG SMARCE1 TARGETS DN | |
| BIOCARTA SKP2E2F PATHWAY | |
| GARY CD5 TARGETS DN | |
| KANG DOXORUBICIN RESISTANCE DN | |
| NCI S1P S1P3 PATHWAY | |
| PYEON HPV POSITIVE TUMORS DN | |
| ZHANG BREAST CANCER PROGENITORS UP | |
| TOOKER GEMCITABINE RESISTANCE DN | |
| SIMBULAN UV RESPONSE IMMORTALIZED DN | |
| ELVIDGE HIF1A TARGETS UP | |
| NCI DIABETES PATHWAYS | |
| SASSON RESPONSE TO GONADOTROPHINS DN | |
| PUIFFE INVASION INHIBITED BY ASCITES DN | |
| BIDUS METASTASIS UP | |
| HAMAI APOPTOSIS VIA TRAIL UP | |
| REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS | |
| KEGG THYROID CANCER | |
| CORUM SEC6/8 EXOCYST COMPLEX | |
| REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | |
| REACTOME SPHINGOLIPID METABOLISM | |
| NCI CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION | |
| KINSEY TARGETS OF EWSR1 FLII FUSION UP | |
| OSMAN BLADDER CANCER UP | |
| NCI TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | |
| WEI MYCN TARGETS WITH E BOX | |
| MOREAUX MULTIPLE MYELOMA BY TACI DN | |
| JI RESPONSE TO FSH DN | |
| HOFMANN MYELODYSPLASTIC SYNDROM RISK UP | |
| ST STAT3 PATHWAY | |
| WENDT COHESIN TARGETS UP | |
| SCHLOSSER MYC TARGETS AND SERUM RESPONSE DN | |
| NCI MRNA 3 END PROCESSING | |
| DEURIG T CELL PROLYMPHOCYTIC LEUKEMIA DN | |
| WAMUNYOKOLI OVARIAN CANCER GRADES 1 2 UP | |
| TOOKER RESPONSE TO BEXAROTENE UP | |
| DODD NASOPHARYNGEAL CARCINOMA DN | |
| HOSHIDA LIVER CANCER SURVIVAL UP | |