| Gene Set | Leading Edge Genes |
|---|
| DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP | POLR2B, EI24, ICT1, ADH5, NDUFA8, BTBD1, POLD2, ECHS1, ANAPC1, TERF1, SREBF1, SPAG7, EIF2AK1, LMAN1, MARCH6, UBE2G1, SEPHS2, HEBP1, DDB1, ACSL5, ALDH6A1, PRKRA, ATF2, NDUFB6, GLO1, WDR13, CLNS1A, PHB2, FZD7, MRPS35, STK11, TM9SF1, C1QBP, SLC25A11, ALAD, NCBP2, SS18, SPTLC1, ARCN1, TAF6, CTNNBL1, POLR2E, FNTA, HMG20B, DPAGT1, MTX2, ATP5J2, ATP5J, PPA2, MPDU1, SSBP1, OXSR1, CAPN7, NDUFAB1, BAG4, PDHB, COPS2, PHYH, TOMM22, SCARB2, UBE2B, NIT2, CMAS, NCOR1, MAP2K2, ACADM, ACAD8, CNOT8, NUDT6, FADS1, PCYT2, HDAC2, IMPA1, RNF5, MRPS31, AUP1, MYCBP, RBBP4, COPS5, CETN2, PRDX4, NGRN, MRPL49, MRPS30, SOLH, CYC1, CUL4A, ATP5O, CPSF1, PEBP1, FDPS, COPS3, DAPK1, CNIH, PPP2R5C, IDH3B, NBR1, NDUFV2, ABCB6, HRSP12, PAPSS1, HBP1, ARL5A, DPM1, WHSC2, PXMP3, PUS1, PECI, CLPX, SDHD, ERGIC3, NDUFA5, STOML2, COMT, PRKAG1, NDUFB5, ORC5L, RREB1, AHCYL1, LANCL1, PDCD2, SLC29A1, SEP15, MLF2, PGRMC2, ZNF22, APEH, HMBS, CDC37, UPF3B, SH3GLB2, FUSIP1, ACO1, MSH6, OAT, ZMPSTE24, ANP32A, CDK8, KIFAP3, ACLY, HMGCS1, GTF2H4 |
| MOOTHA PGC | MRPS18A, MRPS34, SDHA, SACM1L, SLC25A11, COMT, NDUFB5, HSPE1, CYC1, ICT1, NDUFA8, ATP5O, NDUFA6, AMACR, MRPS18B, GUK1, CDC34, COPS3, NDUFAB1, EIF4A2, DDT, MRPL34, NDUFS3, DHX16, NFS1, TIMM8B, NDUFC1, NDUFV2, NDUFS5, ULK1, PDHB, ATP5C1, SDHB, MRPS12, PHYH, IDH3G, UBE2B, FDX1, RPA3, ACADM, MRPL18, SEPX1, NDUFB3, MRPS2, PUS1, APBA3, NDUFB6, PCYT2, COX7C, GTF2H4, MRPL39, STARD7 |
| TIEN INTESTINE PROBIOTICS 24HR UP | MRPL9, NDUFA5, C1QBP, ALAD, TRIAP1, EI24, HSPE1, FBXO3, RDH11, MRPS22, NDUFA8, NDUFA6, EMG1, PPIF, DCXR, CYB5B, MRPS18B, ECHS1, POP5, ATP5J, ENTPD4, FDPS, FBXO9, SPAST, NDUFB2, SUCLA2, EBP, NDUFC1, TIMM8B, LRPPRC, NDUFV2, PDHB, MMD, POLR2L, EXOSC7, CUGBP1, GGA2, TFAM, RPA3, PDCD5, NDUFB3, MRPS2, NDUFA9, TUBG1, MSH6, ACAT2, TSN, OAT, NDUFB6, ACLY, IDI1, HMGCS1, STARD7, DHCR7 |
| STARK PREFRONTAL CORTEX 22Q11 DELETION DN | ARPC5L, TXNDC14, MRPS18A, KRTCAP2, 1110031I02RIK, ATP5H, HSPE1, BSCL2, CYC1, NDUFS8, ADH5, NDUFA8, DDX56, NDUFS6, GUK1, FDPS, LRPAP1, COPS3, PPP2R5C, NDUFB11, TIMM8B, NDUFB10, APOA1BP, NDUFV2, 2410015M20RIK, NDUFS7, COPS6, MRPL41, 3110001D03RIK, MRPS11, SEPHS2, MRPS28, PDCD5, TMEM147, NDUFA9, FKBP2, SRP9, MRPS17, RPL36AL, 2310028O11RIK, CLNS1A, 2810405K02RIK, 2900010M23RIK, IMMP1L, 1110020P15RIK, SEC61B, UQCR, TUSC4, C1QBP, 2310016M24RIK, TMEM126A, DEB1, NDUFS1, MRPS22, UFC1, POLR2J, MKKS, GM561, CHCHD1, HIGD2A, ATP5J, MKI67IP, ATP5E, BCCIP, NDUFAB1, CWF19L1, NDUFB2, PGRMC2, UQCRC2, SRA1, NDUFS3, 2510002D24RIK, ATP5C1, MRPS12, IDH3G, DGCR6, MEA1, LSMD1, TUBG1, BNIP1, D10ERTD322E |
| CORUM RESPIRATORY CHAIN COMPLEX I BETA SUBUNIT MITOCHONDRIAL | NDUFB3, NDUFB7, NDUFB6, NDUFA4, NDUFAB1, NDUFB9, NDUFB2, NDUFB5, NDUFB4, NDUFB11, NDUFB10 |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | RBBP4, SCAP, DALRD3, TOP2B, ZMYM6, DMAP1, ARHGEF10L, ZCCHC17, EI24, NADK, UBIAD1, UTP11L, ECHS1, PAQR7, ORAOV1, QARS, TIMM8B, ZBTB8OS, MRPS16, SIDT2, WHSC2, FDX1, WDR8, JAGN1, PTS, SNX19, CLNS1A, TMEM115, PCGF6, MRPL48, AP3M1, CPSF3L, DDX50, ATP5I, INTS4, RAF1, DNAJC11, NGLY1, NUDC, TMEM126A, RPUSD4, CTNNB1, ELOVL1, CHCHD1, DPAGT1, OXSR1, CAPN7, SEC24C, PEX14, CWF19L1, ZMYM1, HERC4, APEH, MIB2, MED8, HMBS, SDHB, NSUN4, USP48, PARK7, UBP1, PPCS, IQSEC1, ACAD8, HMGCL, ZMPSTE24, DHX30, MRPL43, NMNAT1 |
| REACTOME CITRIC ACID CYCLE | DLST, NNT, DLD, SDHB, SDHA, IDH3G, SDHD, SUCLA2, IDH3B, SDHC |
| CORUM RESPIRATORY CHAIN COMPLEX I LAMBDA SUBUNIT MITOCHONDRIAL | NDUFS6, NDUFV2, NDUFS7, NDUFA5, NDUFV1, NDUFS8, NDUFS1, NDUFS3 |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 17 | COPS5, MRPL2, MRPS34, KRTCAP2, 1500032L24RIK, EI24, EXOC7, MRPS22, UFC1, ICT1, NDUFB7, PDCD2, VPS25, NDUFAB1, LRPAP1, DDT, MRPL34, MRPL16, LIAS, NDUFS3, GRPEL1, CNIH, STUB1, HMBS, 2310003F16RIK, NDUFV2, SDHB, COPS6, MRPS7, MRPS12, MRPS11, NDUFB9, PTPLAD1, MRPL36, DNAJC19, NDUFB6, CSNK2B, HMGCS1, PHB2, STARD7 |
| NCI CITRIC ACID CYCLE TCA CYCLE | IDH3G, SDHB, SDHD, SUCLA2, SDHC, IDH3B, SDHA |
| CORUM RESPIRATORY CHAIN COMPLEX I INCOMPLETE INTERMEDIATE MITOCHONDRIAL | NDUFA9, NDUFS6, NDUFV2, NDUFS7, NDUFS1, NDUFB8, NDUFV1 |
| SHEN SMARCA2 TARGETS UP | RAF1, PEX11B, MTO1, SS18, SPTLC1, FBXO3, FBXW2, CUL4A, HNMT, MKKS, NUMB, ATP5O, RAB14, LANCL1, RMND5A, NSFL1C, CAPN7, UQCRC2, TNPO1, PPP2R5C, NBR1, UBR2, CTCF, TTRAP, NOL7, PDHB, UPF3B, MOCS2, COPS2, RAB40B, DPM1, FUSIP1, UBE2G1, NCOR1, SRP14, CUL4B, PCMTD2, AGGF1, SRP9, RDH14, PRKRA, TSN, ANP32A, NDUFB6, KIFAP3, SDHD, RHOT1, MRPS14, TRIP4 |
| PELLICCIOTTA HDAC IN ANTIGEN PRESENTATION UP | TXNDC12, ERGIC3, SAR1B, SAR1A, COPE, PSMB1, SEC22A, SEC22B, TRAPPC1, PSMC4, WFS1, COPZ1, PSMD2, TRAPPC3, PSMD6, TMED9, PDIA4, PSMB3, COPG, KDELR2 |
| CORUM RESPIRATORY CHAIN COMPLEX I EARLY INTERMEDIATE NDUFAF1 ASSEMBLY MITOCHONDRIAL | NDUFA6, NDUFB6, NDUFA9, NDUFAF1, NDUFS7, NDUFS3 |
| MORI PLASMA CELL UP | LMAN1, RPN1, TMEM39A, BET1, EBP, SSR2 |
| CORUM F1F0-ATP SYNTHASE EC 3.6.3.14 MITOCHONDRIAL | ATP5O, ATP5I, ATP5C1, ATP5D, ATP5G1, ATP5J2, ATP5J, ATP5E, ATP5H, ATP5F1 |
| PENG RAPAMYCIN RESPONSE DN | PSMD5, NDUFA9, ATP5G1, JTB, TGDS, CHUK, MRPS11, STRA13, MRPL12, HSPE1, RABGGTB |
| REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | ATP5O, ATP5I, ATP5C1, ATP5D, ATP5G1, ATP5J2, ATP5J, ATP5E, ATP5H, ATP5F1 |
| NCI FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | ATP5O, ATP5I, ATP5C1, ATP5D, ATP5G1, ATP5J2, ATP5J, ATP5E, ATP5H, ATP5F1 |
| NCI FORMATION OF HIV 1 ELONGATION COMPLEX CONTAINING HIV 1 TAT | POLR2E, RDBP, POLR2F, POLR2I, POLR2L, WHSC2, POLR2B, NCBP2, GTF2H4, POLR2J |
| NCI RNA POL II CTD PHOSPHORYLATION AND INTERACTION WITH CE | |
| NCI RNA POL II CTD PHOSPHORYLATION AND INTERACTION WITH CE1 | |
| NCI TAT MEDIATED ELONGATION OF THE HIV 1 TRANSCRIPT | |
| CORUM RESPIRATORY CHAIN COMPLEX I INTERMEDIATE VII/650KD MITOCHONDRIAL | |
| REACTOME RNA POL II CTD PHOSPHORYLATION AND INTERACTION WITH CE | |
| REACTOME GENE EXPRESSION | |
| REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT | WHSC2, POLR2E, POLR2B, RDBP, NCBP2, POLR2F, POLR2I, POLR2L, POLR2J |
| REACTOME RNA POLYMERASE I III AND MITOCHONDRIAL TRANSCRIPTION | |
| REACTOME MICRORNA BIOGENESIS | POLR2E, POLR2B, POLR2F, POLR2I, POLR2L, POLR2J |
| NCI FORMATION OF THE HIV 1 EARLY ELONGATION COMPLEX | POLR2E, RDBP, POLR2F, POLR2I, POLR2L, WHSC2, POLR2B, NCBP2, GTF2H4, POLR2J |
| CORUM RAP1 COMPLEX | TERF2IP, XRCC5, TERF1 |
| NCI ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT | WHSC2, POLR2E, POLR2B, RDBP, NCBP2, POLR2F, POLR2I, POLR2L, POLR2J |
| CORUM CNS-P53 COMPLEX | COPS3, GPS1, COPS5, COPS7A, COPS6, COPS2 |
| CORUM CSA COMPLEX | DDB1, COPS3, GPS1, COPS5, COPS7A, COPS6, COPS2, CUL4A |
| NCI MRNA CAPPING | POLR2E, POLR2F, POLR2I, POLR2L, POLR2B, NCBP2, GTF2H4, POLR2J |
| NCI FORMATION OF THE EARLY ELONGATION COMPLEX | POLR2E, RDBP, POLR2F, POLR2I, POLR2L, WHSC2, POLR2B, NCBP2, GTF2H4, POLR2J |
| CORUM COP9 SIGNALOSOME COMPLEX | COPS3, GPS1, COPS5, COPS7A, COPS6, COPS2 |
| REACTOME HIV1 TRANSCRIPTION ELONGATION | POLR2E, RDBP, POLR2F, POLR2I, POLR2L, WHSC2, POLR2B, NCBP2, GTF2H4, POLR2J |
| REACTOME TRANSCRIPTION | RDBP, RRN3, UPF3B, POLR2L, TCEB2, POLR2I, GTF3C4, WHSC2, POLR2B, NCBP2, TFAM, TAF6, MNAT1, POLR2J, TFB2M, POLR2E, POLR2F, CPSF1, SFRS2, NFIC, CSTF1, GTF2H4, SNAPC2 |
| NCI HIV 1 TRANSCRIPTION ELONGATION | POLR2E, RDBP, POLR2F, POLR2I, POLR2L, WHSC2, POLR2B, NCBP2, GTF2H4, POLR2J |
| CORUM CSA-POLIIA COMPLEX | DDB1, COPS3, GPS1, COPS5, COPS7A, COPS6, COPS2, CUL4A |
| REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX | POLR2E, RDBP, POLR2F, POLR2I, POLR2L, WHSC2, POLR2B, NCBP2, GTF2H4, POLR2J |
| NCI MICRORNA MIRNA BIOGENESIS | POLR2E, POLR2B, POLR2F, POLR2I, POLR2L, POLR2J |