| Gene Set | Leading Edge Genes |
|---|
| KEGG PARKINSONS DISEASE | COX5A, UQCRH, NDUFA2, SDHC, ATP5O, NDUFA6, NDUFB3, NDUFS6, ATP5A1, COX6B1, UQCRQ, NDUFB6, COX6C, NDUFB2, COX7C, NDUFC1 |
| LINDGREN BLADDER CANCER CLUSTER 3 UP | RFC3, PCNA, RRM2, ATAD2, TMPO, H2AFZ, CCNB1, CENPA, TARS, PLK4, RBBP7, E2F8, ALDH9A1, MCM4, TYMS, CCNB2, HMOX1, TFRC, PEBP1, NASP, SUCLG1, RAD51, PARD6B, TK1, BIRC5 |
| WHITEFORD PEDIATRIC CANCER MARKERS | CDK6, PCNA, RECQL4, RRM2, MLF1IP, TMPO, CCNB1, CENPA, PLK4, PSAT1, TK1, BIRC5, MCM4 |
| ZHANG BREAST CANCER PROGENITORS UP | RRM2, NVL, MTDH, TMPO, H2AFZ, HELLS, MRPS33, PSAT1, PBK, SHCBP1, CALM2, SYNCRIP, SSB, ENPP3, RAD51, PCYOX1, LSM5, NDUFC1, PUS7L |
| PUJANA CHEK2 PCC NETWORK | RFC3, PCNA, MTDH, RRM2, HMGCR, POLE3, TMPO, CCNB1, ZNHIT3, PLK4, RBM34, MNAT1, NDUFB3, PCMT1, RECQL4, SSB, TFRC, UNG, KHDRBS1, CCNE2, POLE2, DNAJC9, COPS3, PRDX3, IDI1 |
| SHEDDEN LUNG CANCER POOR SURVIVAL A6 | RFC3, PCNA, MMP12, RRM2, ATAD2, GPR19, PSAT1, MCM10, E2F8, SHCBP1, HMMR, PCMT1, RECQL4, CCNE2, HEXIM1, POLE2, BIRC5 |
| BLUM RESPONSE TO SALIRASIB DN | BUB1B, RFC3, PCNA, RRM2, TMPO, H2AFZ, RAB40B, CENPA, PLK4, RBBP7, PBK, HMMR, NDUFA2, NDUFB3, RGS2, RECQL4, CCNE2, POLE2, PRDX3, RAD51, CHST12 |
| RHEIN ALL GLUCOCORTICOID THERAPY DN | BUB1B, PRDX6, PCNA, SCCPDH, RRM2, MLF1IP, CCT6A, E2F8, SHCBP1, HMMR, ACAA2, SDHC, MCM4, PCMT1, UNG, POLE2, RAD51, PRDX3, ING2, GBE1, LSM5, ATP5L, BIRC5 |
| CROONQUIST IL6 DEPRIVATION DN | BUB1B, RFC3, PCNA, RRM2, CCNB1, CENPA, PLK4, OIP5, HMMR, MCM4, TYMS, CCNB2, NASP, CCNE2, POLE2, TK1 |
| REACTOME CELL CYCLE MITOTIC | BUB1B, PSMC5, RFC3, CEP76, PCNA, RRM2, MLF1IP, CCNB1, CENPA, PLK4, MCM10, MNAT1, MCM4, CENPJ, CDK6, CCNE2, POLE2, NDE1, BIRC5 |
| GRAHAM CML DIVIDING VS NORMAL QUIESCENT UP | BUB1B, RFC3, CEP76, RRM2, MLF1IP, CCNB1, CENPA, PBK, MCM10, E2F8, OIP5, HMMR, HSPA14, MCM4, AMMECR1, SYNCRIP, CCNE2, POLE2, RAD51, TK1, LSM5, BIRC5 |
| GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING DN | BUB1B, AMMECR1, RFC3, CCNB2, PCNA, RRM2, MLF1IP, CCNE2, CDC45L, POLE2, MCM10, BIRC5, MCM4, TYMS |
| LI WILMS TUMOR VS FETAL KIDNEY 1 DN | |
| REACTOME CELL CYCLE CHECKPOINTS | |
| LEE EARLY T LYMPHOCYTE UP | |
| MORI IMMATURE B LYMPHOCYTE DN | RAD51, E2F8, MCM10, RRM2, CCNB1, CENPA |
| NCI PYRIMIDINE BIOSYNTHESIS INTERCONVERSION | |
| ODONNELL TARGETS OF MYC AND TFRC DN | |
| NCI FOLDING OF ACTIN BY CCT TRIC | |
| ZHAN MULTIPLE MYELOMA PR UP | |
| REACTOME NUCLEOTIDE EXCISION REPAIR | ERCC3, RFC3, PCNA, POLR2C, POLE2, MNAT1, POLR2G |
| NCI COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING | |
| REACTOME MITOTIC PROMETAPHASE | |
| WINNEPENNINCKX MELANOMA METASTASIS UP | PCNA, ENY2, RRM2, SHCBP1, CCNB1, BIRC5, CENPA |
| REACTOME GLOBAL GENOMIC NER | |
| NUYTTEN EZH2 TARGETS DN | |
| CORUM CCT MICRO-COMPLEX | |
| MUELLER PLURINET | BUB1B, RFC3, PCNA, RECQL4, CASP6, SSB, TMPO, CCNB1, RAD51, COPS3, MCM10, HMMR, MNAT1, MCM4, BIRC5 |
| MARKEY RB1 ACUTE LOF DN | PCNA, RRM2, TMPO, H2AFZ, CCNB1, CENPA, DNAJC9, RAD51, E2F8, ZMYND11, BIRC5 |
| NCI CHAPERONIN MEDIATED PROTEIN FOLDING | |
| REACTOME METABOLISM OF PROTEINS | |
| HOFFMANN LARGE TO SMALL PRE BII LYMPHOCYTE UP | |
| STEIN ESRRA TARGETS RESPONSIVE TO ESTROGEN DN | |
| REACTOME TRANSCRIPTION COUPLED NER | ERCC3, RFC3, PCNA, POLR2C, POLE2, MNAT1, POLR2G |
| MORI MATURE B LYMPHOCYTE DN | |
| NCI MITOTIC PROMETAPHASE | |
| YU MYC TARGETS UP | CKS2, PCNA, E2F8, IDI1, BRCA2, CCNB1, BIRC5 |
| CROONQUIST NRAS SIGNALING DN | |
| BOYAULT LIVER CANCER SUBCLASS G23 UP | |
| FERREIRA EWINGS SARCOMA UNSTABLE VS STABLE UP | |
| EGUCHI CELL CYCLE RB1 TARGETS | |
| RUIZ TNC TARGETS DN | ATAD2, RRM2, MLF1IP, TMPO, CCNE2, MCM10, E2F8, SHCBP1, NMT2, BIRC5 |
| REACTOME G1 S TRANSITION | |
| NCI ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | CCT2, CCT5, TCP1, CCT3, CCT6A |
| FOURNIER ACINAR DEVELOPMENT LATE 2 | |
| GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS TURQUOISE DN | |
| REACTOME S PHASE | |
| MORI LARGE PRE BII LYMPHOCYTE UP | |
| KEGG CELL CYCLE | |
| NCI FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | |
| VANTVEER BREAST CANCER METASTASIS DN | |
| REACTOME SYNTHESIS OF DNA | |
| REACTOME MITOTIC M M G1 PHASES | BUB1B, PSMC5, MLF1IP, NDE1, BIRC5, MCM4, CENPA |
| MISSIAGLIA REGULATED BY METHYLATION DN | |
| STEIN ESR1 TARGETS | |
| REACTOME INFLUENZA LIFE CYCLE | |
| KEGG NUCLEOTIDE EXCISION REPAIR | ERCC3, RFC3, PCNA, POLE3, POLE2, MNAT1, GTF2H5 |