| Gene Set | Leading Edge Genes |
|---|
| REACTOME ELECTRON TRANSPORT CHAIN | COX5A, NDUFA13, NDUFA3, NDUFV1, NDUFA10, NDUFB5, NDUFS8, NDUFS1, CYC1, SDHC, ETFB, NDUFS6, NDUFB6, COX6A1, NDUFA4, NDUFS2, COX7C, NDUFB2, SDHD, NDUFS3, NDUFB11, ETFA, NDUFC1 |
| RHEIN ALL GLUCOCORTICOID THERAPY DN | BUB1B, KIF11, MAD2L1, GPR125, PRPS2, STMN1, CAT, PTPLA, RRM1, STOML2, PCCA, CCNG1, E2F8, RFC4, ADSL, MCM4, PSIP1, ECT2, TTK, APEX1, RACGAP1, ACAT1, GMPS, TUBB, NUDT1, HADH, POLE2, ANP32A, AK2, RPA1, MAGED1 |
| PUJANA CHEK2 PCC NETWORK | RFC3, POLE3, ABCE1, TTF2, ILF2, PAXIP1, CENPA, C16ORF80, RFC5, ATP5O, MCM3, GMPS, CPT1A, TMEM106C, NUP88, SMARCA4, CNIH, LMNB2, WDR68, CTR9, CHEK2, KIF11, CAD, AGL, CENPI, DLAT, CDC45L, CCNF, SMC1A, CSE1L, SNRPD3, SLC16A1, MNAT1, LYPLA1, MCM4, CDC20, TPX2, NUDT1, PRKRA, RPIA, MRE11A, RPA1, KIF2C, SEPHS1, RAD51C, GALNT1, STMN1, RAN, NCBP2, ADSL, FTSJ1, WRN, ANAPC5, CENPF, OGG1, TOE1, METAP1, CDC23, RMND5A, WNT11, ATP5J, DDX46, MTA1, SRP72, ZNF22, KNTC1, RECK, BUB1B, CENPC1, LMNB1, MAD2L1, FOXM1, RRM1, RFC4, TTF1, PSIP1, TTK, MSH6, POLR3G, TPP2, POLE2, H2AFV, HDAC2 |
| WONG EMBRYONIC STEM CELL CORE | KIF20A, RFC3, NTHL1, STOML2, NCBP2, CDCA3, SDHC, HSPA14, ATP5O, MCM3, APEX1, NIPSNAP1, MRPL16, BANF1, ZNF22, CHEK2, LMNB1, MAD2L1, CKAP2, DLAT, CCNF, CSE1L, SLC16A1, RRM1, LYPLA1, MCM4, KIF4A, RACGAP1, ACAD8, SNRPD1, HADH, POLE2, NEK2, POLR3K, NT5DC2 |
| KOBAYASHI EGFR SIGNALING 24HR DN | RFC3, ABCE1, CENPA, PBK, E2F8, SHCBP1, RFC5, CDCA3, HSPA14, MCM3, TUBB, PSRC1, BUB1B, KIF11, LMNB1, MAD2L1, ITGA6, CDC45L, RANGAP1, CSE1L, E2F1, RRM1, HMMR, MCM4, KIF4A, ECT2, TUBG1, RACGAP1, TTK, MSH6, CDC20, TPX2, SNRPD1, POLE2, NCAPG2, NEK2, GPSM2, POLR3K, PRC1, KIF2C |
| BIDUS METASTASIS UP | PREPL, LMNB1, KIF11, TTF2, MAD2L1, CENPA, CSE1L, RRM1, PBK, CKAP5, NCBP2, RFC4, FBXO3, PRKDC, RFC5, CENPF, KIF4A, ECT2, RACGAP1, CAND1, TPX2, RMND5A, SNRPD1, ATF2, AZIN1, PHF10 |
| REACTOME CELL CYCLE MITOTIC | BUB1B, KIF20A, RFC3, CENPI, MAD2L1, CENPA, E2F1, RANGAP1, CKAP5, PRKACA, RFC4, ANAPC2, ANAPC5, RFC5, CENPF, MNAT1, MCM4, POLD2, TUBG1, MCM3, TUBB, CDC25C, POLE2, ANAPC1, NEK2, RPA1, KNTC1, KIF2C |
| ODONNELL TFRC TARGETS DN | BUB1B, CDKN3, KIF20A, KIF11, PLK1, CCNB1, CENPA, FOXM1, SHCBP1, HMMR, CCNA2, CENPF, GALT, KIF4A, ECT2, TTK, CDC20, POLE2, RANBP1, PRC1, TACC3, SURF1, BIRC5, ASPM |
| LI WILMS TUMOR VS FETAL KIDNEY 1 DN | |
| REACTOME TELOMERE MAINTENANCE | |
| REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | |
| WAKASUGI HAVE ZNF143 BINDING SITES | |
| MOLENAAR TARGETS OF CCND1 AND CDK4 DN | |
| SCHUHMACHER MYC TARGETS UP | |
| MOREAUX B LYMPHOCYTE MATURATION BY TACI DN | |
| REACTOME GLOBAL GENOMIC NER | |
| KEGG LIMONENE AND PINENE DEGRADATION | |
| NCI APC CDC20 MEDIATED DEGRADATION OF NEK2A | |
| TOYOTA TARGETS OF MIR34B AND MIR34C | |
| MANALO HYPOXIA DN | |
| NCI ACTIVATION OF THE PRE REPLICATIVE COMPLEX | |
| REACTOME EXTENSION OF TELOMERES | |
| REN BOUND BY E2F | |
| REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | |
| SCHLOSSER MYC AND SERUM RESPONSE SYNERGY | |
| KEGG MISMATCH REPAIR | |
| CAIRO HEPATOBLASTOMA CLASSES UP | |
| FOURNIER ACINAR DEVELOPMENT LATE 2 | |
| REACTOME S PHASE | |
| NCI ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | |
| REACTOME DNA REPAIR | |
| ZHANG RESPONSE TO CANTHARIDIN DN | |
| REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | |
| KEGG BASE EXCISION REPAIR | |
| REACTOME INACTIVATION OF APC VIA DIRECT INHIBITION OF THE APCOMPLEX | |
| NCI INACTIVATION OF APC C VIA DIRECT INHIBITION OF THE APC C COMPLEX | |
| GOUYER TATI TARGETS DN | |
| RHODES CANCER META SIGNATURE | |
| KEGG LYSINE DEGRADATION | |
| REACTOME SYNTHESIS OF DNA | |
| SHEDDEN LUNG CANCER POOR SURVIVAL A6 | |
| KEGG PENTOSE AND GLUCURONATE INTERCONVERSIONS | |
| SCIBETTA KDM5B TARGETS DN | |
| NCI REGULATION OF APC C ACTIVATORS BETWEEN G1 S AND EARLY ANAPHASE | |
| KAUFFMANN DNA REPAIR GENES | |
| AMUNDSON GAMMA RADIATION RESPONSE | TTK, MAD2L1, CDC25C, UBE2C, PLK1, TSN, CCNF, CENPA, NEK2, TACC3, CCNA2 |
| STEIN ESR1 TARGETS | |
| REACTOME G2 M CHECKPOINTS | |
| KEGG NUCLEOTIDE EXCISION REPAIR | |
| MOOTHA VOXPHOS | |