| Gene Set | Leading Edge Genes |
|---|
| KEGG PARKINSONS DISEASE | NDUFA3, UQCRH, UBB, NDUFA2, COX7B, ATP5O, UBE2G2, NDUFB3, NDUFS6, COX4I1, COX6B1, UQCRQ, NDUFB6, SLC6A3, ATP5E, COX7C, NDUFB2, NDUFC1 |
| WHITEFORD PEDIATRIC CANCER MARKERS | CDK6, TK1, RECQL4, RRM2, H2AFX, TPX2, TOP2A, CENPF, BIRC5 |
| CROONQUIST IL6 DEPRIVATION DN | CCNB2, RRM2, MKI67, TPX2, POLE2, SPAG5, TK1, SMC4, OIP5, TOP2A, KIF2C, TYMS |
| REACTOME CELL CYCLE MITOTIC | KIF20A, CEP76, CDK5RAP2, RRM2, GINS2, ORC6L, PSMD9, PSMA7, CENPF, NUP85, MNAT1, CENPJ, CDK6, CEP135, FEN1, CDC25C, POLE2, POLE, ODF2, RPS27, KIF2C, BIRC5 |
| GRAHAM CML DIVIDING VS NORMAL QUIESCENT UP | CEP76, RRM2, DLC1, SPAG5, GINS2, H2AFX, OIP5, TOP2A, NUP85, HSPA14, CENPF, KIF4A, FEN1, POLE2, TK1, PRC1, KIF2C, BIRC5, ASPM |
| CROONQUIST NRAS SIGNALING DN | MKI67, TPX2, CDC25C, SPAG5, TK1, H2AFX, OIP5, SMC4, TOP2A, KIF2C |
| REACTOME INSULIN SYNTHESIS AND SECRETION | RPL27, RPS11, RPL24, RPL38, RPS6, RPS16, RPLP0, RPL32, RPS8, RPL13A, RPL17, RPL3, RPS15A, RPS18, RPLP1, PCSK1, RPS10, RPS21, RPS23, RPS19, RPS12, RPL30, RPS7, RPL7A, RPS29, RPS13, RPL19, RPL15, NKX2-2, RPL31, RPL35A, RPS27, RPL7 |
| KANG DOXORUBICIN RESISTANCE UP | KIF4A, RRM2, MKI67, TPX2, CENPA, FOXM1, TK1, PRC1, NCAPG, OIP5, HMMR, TOP2A, ASPM, BIRC5, MCM4 |
| TANG SENESCENCE TP53 TARGETS DN | KIF4A, CCNB2, PPL, SPAG5, TK1, PRC1, TOP2A, BIRC5 |
| AMUNDSON GAMMA RADIATION RESPONSE | CCNB2, KIFC1, CDC25C, CENPA, AURKA, H2AFX, TACC3, CENPF |
| CHEMNITZ RESPONSE TO PROSTAGLANDIN E2 UP | |
| CORUM TRBP CONTAINING COMPLEX DICER RPL7A EIF6 MOV10 AND SUBUNITS OF THE 60S RIBOSOMAL PARTICLE | |
| NCI TRANSLATION INITIATION COMPLEX FORMATION | RPS15A, RPS11, RPS18, RPS3A, RPS6, RPS10, RPS21, RPS16, RPS23, RPS19, RPS12, RPS7, RPS29, RPS13, RPS8, RPS24, RPS27, PABPC1 |
| MITSIADES RESPONSE TO APLIDIN DN | |
| KUMAMOTO RESPONSE TO NUTLIN 3A DN | KIFC1, CENPF, KIF2C, SPAG5 |
| MORI IMMATURE B LYMPHOCYTE DN | H2AFV, RRM2, PRC1, H2AFX, SMC4, TOP2A |
| ODONNELL TARGETS OF MYC AND TFRC DN | FOXM1, TOP2A, CENPF, HELLS, POLE2, BIRC5 |
| GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING DN | CCNB2, FEN1, RRM2, CDC45L, POLE2, GINS2, OIP5, TOP2A, KIF2C, BIRC5 |
| REACTOME NUCLEOTIDE EXCISION REPAIR | ERCC3, ERCC4, POLE, MNAT1, POLR2G, POLE2 |
| ODONNELL TFRC TARGETS DN | KIF4A, KIF20A, RRM2, MKI67, POLE2, DLEU2, PRC1, SHCBP1, NRTN, TOP2A, CENPF, BIRC5, ASPM |
| MODY HIPPOCAMPUS PRENATAL | RPS8, RPL30, H2AFV, H2AFX, RPS27, TOP2A, RPL19 |
| REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | RPL27, RPS11, RPL24, RPL38, RPS3A, RPS6, RPS16, RPLP0, RPL32, RPS8, RPL13A, RPL17, RPL3, RPS15A, RPS18, RPLP1, RPS10, RPS21, RPS23, RPS19, RPS12, RPL30, RPS7, RPL7A, RPS29, RPS13, RPL19, RPL15, NKX2-2, RPL31, RPL35A, RPL7, RPS27, RPS24 |
| NCI GTP HYDROLYSIS AND JOINING OF THE 60S RIBOSOMAL SUBUNIT | RPL27, RPS11, RPL24, RPL38, RPS3A, RPS6, RPS16, RPLP0, RPL32, RPS8, RPL13A, RPL3, RPS15A, RPS18, RPLP1, RPS10, RPS21, RPS23, RPS19, RPS12, RPL30, RPS7, RPL7A, RPS29, RPS13, RPL19, RPL15, RPL31, RPL35A, RPS27, RPS24, RPL7 |
| NCI CAP DEPENDENT TRANSLATION INITIATION | RPL27, RPS11, RPL24, RPL38, RPS3A, RPS6, RPS16, RPLP0, RPL32, RPS8, RPL13A, RPL3, RPS15A, RPS18, RPLP1, RPS10, RPS21, RPS23, RPS19, RPS12, RPL30, RPS7, RPL7A, RPS29, RPS13, RPL19, RPL15, RPL31, RPL35A, RPS27, RPS24, RPL7 |
| STEIN ESRRA TARGETS RESPONSIVE TO ESTROGEN DN | |
| REACTOME TRANSCRIPTION COUPLED NER | ERCC3, ERCC4, PCNA, POLE, POLR2C, POLE2, MNAT1, POLR2G |
| NCI FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | RPS15A, RPS11, RPS18, RPS3A, RPS6, RPS10, RPS21, RPS16, RPS23, RPS19, RPS12, RPS7, RPS13, RPS29, RPS8, RPS24, RPS27 |
| REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | RPS15A, RPS11, RPS18, RPS3A, RPS6, RPS10, RPS21, RPS16, RPS23, RPS19, RPS12, RPS7, RPS13, RPS29, RPS8, RPS24, RPS27 |
| MORI MATURE B LYMPHOCYTE DN | |
| NCI RIBOSOMAL SCANNING AND START CODON RECOGNITION | RPS15A, RPS11, RPS18, RPS3A, RPS6, RPS10, RPS21, RPS16, RPS23, RPS19, RPS12, RPS7, RPS29, RPS13, RPS8, RPS24, RPS27 |
| CORUM 40S RIBOSOMAL SUBUNIT CYTOPLASMIC | RPS15A, RPS11, RPS18, RPS17, RPS3A, RPS6, RPS10, RPS14, RPS16, RPS21, RPS23, RPS19, RPS12, RPS7, RPS29, RPS13, RPS8, RPS27, RPS24 |
| REACTOME GTP HYDROLYSIS AND JOINING OF THE 60S RIBOSOMAL SUBUNIT | RPL27, RPS11, RPL24, RPL38, RPS3A, RPS6, RPS16, RPLP0, RPL32, RPS8, RPL13A, RPL17, RPL3, RPS15A, RPS18, RPLP1, RPS10, RPS21, RPS23, RPS19, RPS12, RPL30, RPS7, RPL7A, RPS29, RPS13, RPL19, RPL15, RPL31, RPL35A, RPL7, RPS27, RPS24 |
| CAIRO HEPATOBLASTOMA CLASSES UP | SLC25A3, NCAPD2, RRM2, UBAP2, GINS2, ZNHIT3, SPAG5, RPS16, DLST /// DLSTP, NUFIP1, OIP5, TOP2A, CENPF, MNAT1, KIF4A, DDX1, AP2B1, KIAA1797, TPX2, CDC25C, CCT5, GRK6, DNAJC9, SUPT4H1, PRC1, DNMT3A, KIF2C, EXOSC2, BIRC5, ASPM |
| FOURNIER ACINAR DEVELOPMENT LATE 2 | |
| REACTOME S PHASE | PSMD9, FEN1, ORC6L, POLE2, PSMA7, MNAT1, GINS2 |
| MORI LARGE PRE BII LYMPHOCYTE UP | |
| REACTOME REGULATION OF BETA CELL DEVELOPMENT | |
| CHANG CYCLING GENES | FOXM1, ARL4A, RECQL4, TACC3, PSRC1, CDC25C, TOP2A, GINS2 |
| REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | RPL27, RPS11, RPL24, RPL38, RPS3A, RPS6, RPS16, RPLP0, RPL32, POLR2G, RPS8, RPL13A, RPL17, RPL3, RPS15A, RPS18, RPLP1, RPS10, RPS21, RPS23, RPS19, RPS12, RPL30, RPS7, RPL7A, RPS29, RPS13, RPL19, RPL15, RPL31, RPL35A, RPL7, RPS27, RPS24 |
| WONG EMBRYONIC STEM CELL CORE | RRM2, NCAPD2, SPAG5, RPS16, FH, EXO1, TOP2A, PSMA7, RPS19, KIF4A, ZIC3, CCT5, POLE2, AMOTL2, DPP3, RPS27, PABPC1, TIMM8B, BIRC5 |
| JEON SMAD6 TARGETS DN | |
| REACTOME TRANSLATION INITIATION COMPLEX FORMATION | RPS15A, RPS11, RPS18, RPS3A, RPS6, RPS10, RPS21, RPS16, RPS23, RPS19, RPS12, RPS7, RPS29, RPS13, RPS8, RPS24, RPS27, PABPC1 |
| REACTOME SYNTHESIS OF DNA | PSMD9, FEN1, ORC6L, POLE2, PSMA7, GINS2 |
| CORUM 60S RIBOSOMAL SUBUNIT CYTOPLASMIC | |
| REACTOME TRANSLATION | RPL27, RPS11, EEF1B2, RPL24, RPL38, RPS3A, RPS6, RPS16, RPLP0, RPL32, RPS8, RPL13A, RPL17, RPL3, PABPC1, RPS15A, RPS18, RPLP1, RPS10, RPS21, RPS23, RPS19, RPS12, RPL30, RPS7, RPL7A, RPS29, RPS13, RPL19, RPL15, RPL31, RPL35A, RPL7, RPS24, RPS27 |
| MISSIAGLIA REGULATED BY METHYLATION DN | |
| NCI L13A MEDIATED TRANSLATIONAL SILENCING OF CERULOPLASMIN EXPRESSION | RPL27, RPS11, RPL24, RPL38, RPS3A, RPS6, RPS16, RPLP0, RPL32, RPS8, RPL13A, RPL3, PABPC1, RPS15A, RPS18, RPLP1, RPS10, RPS21, RPS23, RPS19, RPS12, RPL30, RPS7, RPL7A, RPS29, RPS13, RPL19, RPL15, RPL31, RPL35A, RPL7, RPS27, RPS24 |
| KEGG NUCLEOTIDE EXCISION REPAIR | ERCC3, ERCC4, POLE, POLE2, MNAT1, GTF2H5 |
| REACTOME INFLUENZA LIFE CYCLE | RPL27, RPS11, RPL24, RPL38, RPS6, RPLP0, RPS16, RPL32, NUP85, POLR2G, RAE1, RPS8, RPL13A, RPL17, RPL3, RPS15A, RPS18, RPLP1, RPS10, RPS21, CLTA, RPS23, RPS19, RPS12, RPL30, RPL7A, RPS7, RPS29, RPS13, RPL19, RPL15, RPL31, RPL35A, RPS27, RPL7 |