| Gene Set | Leading Edge Genes |
|---|
| MOOTHA HUMAN MITODB 6 2002 | BCS1L, DNM1L, HLCS, PCCA, MRPL12, MTIF2, OXCT1, NDUFS8, SLC25A16, NDUFA8, NDUFS6, MUT, PDHA1, NDUFS2, DIABLO, SLC25A10, DECR1, MTHFD1, VDAC3, SCP2, COX4NB, MRPS28, TOMM20, CYB5A, MRPL18, NDUFS4, HADH, ACSL5, NDUFB6, BCKDK, PRDX3, COX8A, ATP5B, IDH2, MDH2, MRPL48, PCK2, NDUFB8, MRPL17, TIMM17A, SLC25A11, BDH1, UQCRFS1, NDUFS1, UQCRC1, TSFM, POLG, MBD3, TUFM, ATP5J2, BCAT2, REXO2, AK2, BCKDHA, COX6C, NDUFS3, MFN2, ABAT, GOT1, PDHB, SDHB, SARDH, ACSL1, TOMM22, TFAM, ACADM, ACAA2, MRPS15, NDUFA2, ACAD8, GPD2, GCAT, MRPS14, ATP5L, ACADSB, MRPL49, NDUFA1, CYC1, ATP5O, ATP5S, ACSL3, SUCLA2, ACADVL, ALAS1, NDUFC1, NDUFV2, NDUFS5, MRPS16, DCI, IMMT, OGDH, APAF1, DGUOK, ETFB, NDUFA9, ACAT1, PCCB, HADHA, NDUFA4, ACADS, MKRN2, NNT, ATP5I, MLYCD, UQCR, NME4, MRPS34, UQCRH, SDHA, ETFDH, HADHB, CPT2, DAP3, HTATSF1, NDUFB5, IVD, SLC25A4, ATP5G1, CYB5B, CYB5R3, UQCRC2, NDUFB2, MRPL16, HAX1, TOMM40, SLC25A15, ATP5C1, IDH3A, IDH3G, ACO2, SLC9A6, NDUFB3, PYCR1, SLC25A17, ALDH2, SLC25A5, SUCLG1, ATP5G3 |
| STEIN ESRRA TARGETS UP | NNT, SLC31A1, MMACHC, PFKM, SEC23B, TRAK2, ACADSB, MGST3, TEX2, NDRG4, ACY1, ST3GAL5, ETFDH, AK1, BRP44, TRIM2, ABLIM1, ATP5O, MDH1, ATP5G1, SLC25A4, GSTM1, MUT, METTL7A, UGP2, PDHA1, PXMP4, NDUFS2, ACYP1, LETMD1, GMCL1, YIPF2, SUCLA2, NANS, MFN2, DECR1, GSTM2, CKB, GOT1, ATP5C1, SDHB, EPN3, PPIC, EHHADH, NUDT3, HTATIP2, ACAA2, ACADM, DCI, OGDH, ILVBL, ANXA6, NDUFA9, ACAT1, ST6GALNAC4, SUCLG1, ATP1B1, IMPA1, RNF5, LEFTY1 |
| REACTOME ELECTRON TRANSPORT CHAIN | NDUFB8, UQCRH, ETFDH, SDHA, NDUFA1, NDUFB5, CYC1, NDUFS1, UQCRFS1, NDUFS8, NDUFA8, UQCRC1, NDUFS6, NDUFS2, COX6C, UQCRC2, NDUFB2, NDUFS3, NDUFB11, NDUFC1, COX5A, NDUFV2, NDUFS5, SDHB, NDUFB9, NDUFA2, ETFB, NDUFB3, NDUFA9, NDUFS4, NDUFA4, NDUFB6, COX8A |
| MOOTHA VOXPHOS | BCS1L, ATP5I, NDUFA3, UQCR, NDUFB8, UQCRH, SDHA, ATP5H, NDUFA1, NDUFB5, CYC1, NDUFS1, NDUFS8, UQCRFS1, NDUFA8, UQCRC1, ATP5O, NDUFS6, ATP5G1, MBD3, ATP5J2, ATP5E, NDUFS2, COX6C, NDUFB2, UQCRC2, NDUFS3, NDUFC1, NDUFS5, SDHB, ATP5C1, NDUFB4, CYB5A, NDUFB3, NDUFA9, NDUFS4, NDUFA4, NDUFB6, ATP5G3, COX8A, ATP5B, ATP5L |
| RHEIN ALL GLUCOCORTICOID THERAPY DN | INTS8, CETN2, PRDX4, CDK4, SPARC, PCCA, CANX, OXCT1, SH3BGRL, GPX7, HMGN2, MCTS1, HDDC2, UGP2, METTL5, MPP1, ATP9A, KIF11, GPR125, COPS6, EHBP1, CEP55, NUCB2, MYH10, SCP2, CYB5A, ACAT1, PCCB, NUDT1, ALDH6A1, HADH, GLO1, PRDX3, TALDO1, IDH2, PFKM, PRPS2, AHCY, STMN1, STOML2, NDUFB5, TOP2A, MDH1, PDIA6, CCT8, TUFM, GDI2, TMEM135, AK2, FHL1, MAGED1, ZFAND1, RSU1, ATP5C1, ITGB3BP, ACADM, ACAA2, HMMR, PSIP1, CCNB2, TTK, ECT2, POLE2, CALM1, RPL31, DARS, ATP5L |
| KEGG PROPANOATE METABOLISM | ACAT1, PCCB, MUT, ALDH6A1, ALDH7A1, ALDH2, SUCLG1, PCCA, EHHADH, HIBCH, SUCLA2, ACADM, ABAT |
| SHEN SMARCA2 TARGETS UP | TRAK2, PRKAR1A, IDS, OSTM1, DLG1, STAG1, FBXO3, AASDHPPT, MECP2, ATP5O, MAP4K5, SP3, DDX1, CAND1, SLC30A5, ITFG1, ACTR10, METTL5, SUCLA2, RYK, RNF38, SUCLG2, NBR1, ATG3, SCFD1, NOL7, MLH1, GYG1, WDFY3, PHKB, CSE1L, SMC3, TMEM126B, SRP9, SERINC1, RDX, PRKRA, HMG20A, VBP1, PJA2, NDUFB6, XRCC5, PEX19, HIBCH, SLC25A12, USP1, TROVE2, ARFIP1, ARHGAP5, NNT, RB1, SEPHS1, TAF9B, COMMD10, PEX11B, MTO1, DHX29, ANKMY2, ARHGAP29, MAPK9, HTATSF1, SS18, BRWD2, FBXW2, ERCC3, RAB14, RMND5A, TMEM14A, AKAP11, TMED7, TMEM135, CAPN7, DDX46, RAB4A, UQCRC2, ACVR1, ZDHHC6, SNX5, UNC50, TLK1, CENPC1, PDHB, SENP6, MOCS2, COPS2, ORC4L, SMARCA2, TMED10, SNX2, PSMF1, USP9X, CUL2, DERA, APPBP2, RDH14, PSMD12, RCOR3, PURA, PCNP, SUCLG1, ANP32A, H2AFV, KIFAP3, TRAPPC4, RHOT1, MRPS14, PKN2 |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 14 | FKBP11, RB1, SEC61B, THOP1, TUBB3, CDK4, YKT6, EIF2B5, MRPL12, CARM1, D17WSU104E, SYNCRIP, PSMB5, CCT8, VCL, SSR2, PREP, PTP4A3, 1110036O03RIK, GSTM2, GOLGA5, SERPINH1, HTRA2, CAD, IRAK1, SSR3, ASL, MRPS28, TYMS /// TYMS-PS, PTOV1, COL18A1, GORASP2, SMYD2, NSBP1, SEC61A1, RCN1, LMAN2, MORF4L2, 2900010M23RIK, SLC39A7, NDE1 |
| REACTOME CITRIC ACID CYCLE | DLST, NNT, SDHB, SUCLG1, SDHA, IDH3G, ACO2, SUCLA2, IDH2, SUCLG2, OGDH |
| TARTE PLASMA CELL VS B LYMPHOCYTE UP | CAV1, PRDX4, PYGB, NUCB2, RPN2, SLC35B1, FUT8, P4HB, GGCX, TRAM1, FKBP2, PYCR1, PDIA6, ARF4, PDIA5, LMAN2 |
| GRAHAM CML DIVIDING VS NORMAL QUIESCENT UP | KIF20A, CDKN3, PRDX4, CCNB1, STMN1, CENPA, PBK, HIST1H1C, SFXN1, TOP2A, FBXO5, SYNCRIP, ABCD3, STK39, MICAL2, GSPT1, SAMM50, SUCLA2, ASPM, TPM1, KIF11, ITGB3BP, MRPS28, RPA3, HMMR, CCNA2, MRPS15, CCNB2, TTK, ECT2, CDC20, NUDT1, CCNE2, POLE2, IDH2, NT5DC2 |
| NCI INSULIN SYNTHESIS AND SECRETION | KIF5B, TRAM1, SPCS3, SRP9, CPE, SEC61B, SSR3, RPN2, SSR4, SSR2, SPCS2, SRPR, SPCS1, DDOST, SRP72, STT3B, SRPRB |
| REACTOME MEMBRANE TRAFFICKING | AP3S1, ARFGAP1, SAR1B, COPE, SNX2, SEC31A, TXNDC5, COPZ1, AP1G1, CLTC, SORT1, COPB1, COPB2, COPA, COPG, ARRB1, TPD52L1, SNX5 |
| KEGG CITRATE CYCLE TCA CYCLE | |
| FLECHNER BIOPSY KIDNEY TRANSPLANT REJECTED VS OK DN | |
| KEGG FATTY ACID METABOLISM | |
| BIOCARTA BARRESTIN PATHWAY | |
| NCI COPI MEDIATED TRANSPORT | |
| REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | |
| SMITH TERT TARGETS UP | |
| SCHUHMACHER MYC TARGETS UP | |
| REACTOME INTEGRATION OF ENERGY METABOLISM | |
| SHAFFER IRF4 TARGETS IN MYELOMA VS MATURE B LYMPHOCYTE | |
| ZHANG BREAST CANCER PROGENITORS UP | |
| WOO LIVER CANCER RECURRENCE DN | |
| COLDREN GEFITINIB RESISTANCE UP | |
| WEBER METHYLATED IN COLON CANCER | |
| RODRIGUES THYROID CARCINOMA UP | |
| HAMAI APOPTOSIS VIA TRAIL UP | |
| NAKAMURA CANCER MICROENVIRONMENT DN | |
| REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | |
| RODWELL AGING KIDNEY NO BLOOD DN | |
| PETRETTO HEART MASS QTL CIS UP | |
| NETPATH ANDROGEN RECEPTOR PATHWAY UP | |
| KEGG GLYOXYLATE AND DICARBOXYLATE METABOLISM | |
| KEGG BUTANOATE METABOLISM | |
| CHUANG OXIDATIVE STRESS RESPONSE DN | |
| REACTOME PYRUVATE METABOLISM AND TCA CYCLE | |
| SCHLOSSER MYC TARGETS REPRESSED BY SERUM | |
| REACTOME CLATHRIN DERIVED VESICLE BUDDING | |
| KAAB HEART ATRIUM VS VENTRICLE DN | |
| KEGG PYRUVATE METABOLISM | |
| LANDIS ERBB2 BREAST PRENEOPLASTIC DN | |
| SCHLOSSER MYC TARGETS AND SERUM RESPONSE DN | |
| REACTOME COPI MEDIATED TRANSPORT | |
| DAVICIONI PAX FOXO1 SIGNATURE IN ARMS UP | |