| Gene Set | Leading Edge Genes |
|---|
| MOOTHA HUMAN MITODB 6 2002 | ACADL, NDUFA3, MRPL49, MRPL12, NDUFS8, NDUFA8, ATP5O, FIBP, FECH, SDS, MUT, ECHS1, CPT1A, COX7A2L, TK1, ACADVL, SLC25A10, NDUFC1, TIMM8B, NDUFV2, DLAT, SCP2, COX4NB, APAF1, ACAT1, STARD3, HADH, ACSL5, NDUFA4, BCKDK, ACADS, MKRN2, COX7C, MRPS35, PCK2, NNT, ATP5I, UQCR, ATP5G2, NDUFB8, UQCRH, MRPS33, PTPRA, CPT2, BLVRA, IVD, UQCRC1, MBD3, TUFM, ATP5J2, ATP5J, ATP5E, MTCH1, BAK1, BCKDHA, COX6C, MRPL46, ATP5C1, UCP2, TOMM22, ACAA2, ACADM, MRPS15, NDUFB3, SLC25A17, OAT, MRPS14, ENDOG, ATP5L |
| MOOTHA MITOCHONDRIA | MYCBP, NDUFA3, ACADL, MRPL49, MRPL12, NDUFS8, NDUFA8, ATP5O, FIBP, FECH, MUT, ECHS1, CPT1A, ACADVL, SLC25A10, NDUFC1, TIMM8B, NDUFV2, MRPL41, DLAT, PYGB, COX4NB, APAF1, TP53, ACAT1, PECI, STARD3, HADH, NDUFA4, BCKDK, DCTN6, ACADS, MKRN2, COX7C, MRPS35, PCK2, NNT, ATP5I, UQCR, ATP5G2, NDUFB8, UQCRH, MRPS33, PTPRA, CROT, IVD, UQCRC1, MBD3, TUFM, ATP5J2, ATP5J, ATP5E, MTCH1, BAK1, BCKDHA, COX6C, NFS1, ATP5C1, UCP2, TOMM22, ACAA2, ACADM, MRPS15, NDUFB3, SLC25A17, OAT, SLC25A23, MRPS14, ATP5L |
| REACTOME INTEGRATION OF ENERGY METABOLISM | NNT, ATP5I, NDUFA3, NDUFB8, UQCRH, NDUFA11, CPT2, NDUFS8, NDUFA8, UQCRC1, NDUFB7, ATP5O, ATP5J2, ATP5J, ATP5E, COX7A2L, COX6C, NDUFB10, NDUFC1, PPP2R5D, NDUFV2, NDUFA13, GNB1, ATP5C1, DLAT, ADCY7, NDUFB3, NDUFA4, COX7C, ACLY, STK11, ATP5L |
| SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN UP | KIF20A, HDAC1, PCK2, ATP5I, SART1, NDUFA3, ATP5G2, GIPC1, NDUFB8, POLR2I, VASP, CSNK1G2, UBL5, EI24, IVD, ICMT, HMGB3, NDUFS8, BLOC1S1, NSDHL, AES, UQCRC1, RXRA, EMD, DCXR, CDK2AP2, DPAGT1, MBD3, CST3, ATP5J2, ATP5J, DHCR24, PKD2, KIF22, B4GALT1, DDT, MLF2, COX6C, MTHFS, GOLGA2, HMBS, EBP, DOK1, NDUFV2, RTN3, CD97, SCAND1, UCP2, MAP2K2, HMGB1, APAF1, TP53, FKBP2, HEXIM1, PSMD13, ALDH6A1, TMC6, H2AFV, PSMB3, HMGCS1, HSD17B4, DHCR7 |
| TIEN INTESTINE PROBIOTICS 24HR UP | KIF20A, FAIM, MGST3, TMPO, UBL5, CENPA, ALAD, EI24, ADSL, FBXO3, ICMT, RDH11, NDUFA8, ERCC3, DCXR, CBFB, NTAN1, ATP5J2, ECHS1, ATP5J, SYNGR2, DHCR24, UROD, MTCH1, LRPAP1, TK1, VAMP8, ISOC1, EBP, NDUFC1, TIMM8B, NDUFV2, TPCN1, NDUFA13, UBE2D1, MMD, POLR2L, HSBP1, PHB, ACAA2, NDUFB3, GMNN, TUBG1, NSF, MSH6, ACAT2, TSN, OAT, H2AFV, ACLY, IDI1, HMGCS1, TM7SF3, PON2, ATP5L, DHCR7 |
| KEGG PARKINSONS DISEASE | NDUFV2, ATP5C1, NDUFA3, ATP5G2, NDUFB8, UQCRH, VDAC1, CASP3, NDUFS8, APAF1, NDUFA8, NDUFB3, ATP5O, ATP5J, ATP5E, NDUFA4, COX7A2L, COX6C, COX7C, NDUFB10, NDUFC1 |
| KEGG ALZHEIMERS DISEASE | NDUFV2, ATP5C1, NDUFA3, ATP5G2, NDUFB8, UQCRH, CASP3, CAPN1, MAPK3, PLCB3, NDUFS8, NDUFA8, NDUFB3, ATP5O, APH1A, ATP5J, NDUFA4, ATP5E, COX7A2L, COX7C, NDUFC1, NDUFB10 |
| KEGG FATTY ACID METABOLISM | ACAT1, ACADL, ACAT2, PECI, CPT1A, ACSL5, HADH, ACADS, CPT2, ALDH9A1, ACAA2, ACADM |
| NUYTTEN EZH2 TARGETS DN | YIPF4, PCK2, GMPR2, ORMDL2, LIMD2, TBL1XR1, TMPO, SSX2IP, GTPBP3, MRPS33, CENPA, SS18, SYPL1, CANX, PREB, TMEM19, HMGB3, FIBP, SLC29A1, AUH, CDK2AP2, RAP2A, MND1, ANKRA2, ISOC1, RAB13, F2R, LXN, HMBS, ASPM, NDUFB10, NDUFV2, APOA1BP, CASP6, HSBP1, MIF4GD, DDHD2, CMAS, OMA1, HMGB1, PCMTD2, KLHDC5, ADD1, GMNN, FBXO21, PIGP, RAD54L, FADS1, MARCH2, TSN, MBTPS1, H2AFV, IDI1, ODF2, MRPS35, RFWD3, NT5DC2, NDE1, BIRC5 |
| STARK PREFRONTAL CORTEX 22Q11 DELETION DN | IMMP1L, 1110058L19RIK, TUSC4, UQCR, SEC61B, DYNLRB1, NDUFA11, 1110031I02RIK, BLVRA, NDUFS8, NDUFA8, D16H22S680E, RAB4B, NTAN1, UGP2, ATP5J, TMEM165, ATP5E, LRPAP1, EIF2B4, 2510002D24RIK, PPP2R5C, TIMM8B, NDUFB10, APOA1BP, NDUFV2, ATP5C1, SCAND1, COPS6, PFDN5, MRPL41, PPT1, PSMC3, 3110001D03RIK, MRPL40, SEPHS2, PPP1CA, DGCR6, LSMD1, TUBG1, FKBP2, SRP9, 2700094K13RIK, ACAT2, IDH1, DCTN6, 2610524H06RIK, PSMB3, D10ERTD322E, SNRPD2, CCDC56, SPSB3, 2900010M23RIK |
| KEGG VALINE LEUCINE AND ISOLEUCINE DEGRADATION | ACAT1, AUH, ACAT2, HADH, MUT, AOX1, ACADS, BCKDHA, ALDH9A1, HMGCS1, IVD, ACAA2, ACADM |
| MOOTHA FFA OXYDATION | ACAT1, ACADL, CPT1A, ECHS1, HADH, CPT2, ACADS, ACAA2, ACADM, ACADVL |
| JI RESPONSE TO FSH UP | FDFT1, FADS2, IDI1, FCGRT, CTNNB1, FADS1, EBP |
| REACTOME CHOLESTEROL BIOSYNTHESIS | FDFT1, IDI1, HMGCS1, EBP, DHCR7, NSDHL, DHCR24 |
| REACTOME REGULATION OF APC ACTIVATORS BETWEEN G1 S AND EARLY ANAPHASE | PSMA1, PSMD6, UBE2D1, CDC23, PSMD13, ANAPC1, PSMC3, ANAPC4, CDK2, PSMB3, ANAPC2, ANAPC5, PSMA7, PSME1 |
| MORI PLASMA CELL UP | BPGM, LMAN1, MGAT2, RPN1, DDOST, NANS, BET1, EBP |
| NCI AUTODEGRADATION OF CDH1 BY CDH1 APC C | |
| NCI TRANSFORMATION OF LANOSTEROL TO CHOLESTEROL | |
| KEGG CITRATE CYCLE TCA CYCLE | |
| REACTOME CDC20 PHOSPHO APC MEDIATED DEGRADATION OF CYCLIN A | |
| NCI PHOSPHORYLATION OF THE APC C | |
| THEILGAARD NEUTROPHIL AT SKIN WOUND DN | |
| KEGG HUNTINGTONS DISEASE | |
| BIOCARTA ERK5 PATHWAY | |
| REACTOME PEROXISOMAL LIPID METABOLISM | |
| CORUM F1F0-ATP SYNTHASE EC 3.6.3.14 MITOCHONDRIAL | ATP5E, ATP5O, ATP5I, ATP5C1, ATP5J2, ATP5J, ATP5L |
| NCI APC C CDC20 MEDIATED DEGRADATION OF SECURIN | |
| WONG MITOCHONDRIA GENE MODULE | |
| REACTOME DIABETES PATHWAYS | |
| DAIRKEE TERT TARGETS UP | |
| REACTOME GLUCOSE REGULATION OF INSULIN SECRETION | |
| NCI CDC20 PHOSPHO APC C MEDIATED DEGRADATION OF CYCLIN A | |
| REACTOME REGULATION OF INSULIN SECRETION | |
| NCI CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | |
| REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | ATP5E, ATP5O, ATP5I, ATP5C1, ATP5J2, ATP5J, ATP5L |
| REACTOME APCDC20 MEDIATED DEGRADATION OF CYCLIN B | |
| NCI FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | |
| NCI REGULATION OF APC C ACTIVATORS BETWEEN G1 S AND EARLY ANAPHASE | |
| REACTOME TRANSFORMATION OF LANOSTEROL TO CHOLESTEROL | |
| REACTOME PHOSPHORYLATION OF THE APC | |