| Gene Set | Leading Edge Genes |
|---|
| WONG MITOCHONDRIA GENE MODULE | GSTO1, MRPS18A, NDUFA3, ATP5G2, NDUFB8, ATOX1, MCCC2, MRPL49, NDUFA1, NDUFS8, CYC1, ATP5O, NDUFS6, ATP5G1, ATP5J2, TUFM, ECHS1, CPT1A, ATP5E, NDUFS2, NDUFB2, COX6C, NDUFS3, SURF1, DECR1, NFS1, NDUFC1, PDHB, MRPS16, TIMM17B, DCI, CYB5A, NDUFB3, GSTZ1, PCCB, CLPP, SUCLG1, FDXR, NDUFB6, NDUFA4, ATP5G3, COX8A, GCAT, COX7C |
| MOOTHA MITOCHONDRIA | UQCR, NDUFA3, MRPL2, MRPS18A, NDUFB8, SDHA, CROT, BDH1, MRPL49, NDUFA1, TST, CYC1, NDUFS1, ATP5O, UQCRC1, NDUFS6, ATP5G1, ALDH4A1, MBD3, TUFM, ECHS1, CYB5R3, NDUFB2, COX6C, NDUFS3, IDH3B, ABAT, DECR1, SLC25A3, CAD, PDHB, MRPS16, MRPL35, MRPS11, CAT, TIMM17B, FPGS, DCI, NDUFB3, ETFB, PYCR1, PCCB, HADHA, SUCLG1, FDXR, BCKDK, CS, ATP5G3, COX8A, COX7C, MRPL48 |
| MOOTHA HUMAN MITODB 6 2002 | UQCR, NDUFA3, MRPL2, MRPS18A, NDUFB8, SDHA, BDH1, MRPL49, NDUFA1, TST, CYC1, NDUFS1, ATP5O, UQCRC1, ATP5G1, ALDH4A1, MBD3, ECHS1, TUFM, CYB5R3, NDUFB2, COX6C, NDUFS3, IDH3B, ABAT, DECR1, SLC25A3, PDHB, MRPS16, MRPS11, TIMM17B, FPGS, DCI, NDUFB3, ETFB, PYCR1, PCCB, HADHA, SUCLG1, FDXR, BCKDK, CS, ATP5G3, COX8A, GCAT, MRPL48 |
| REACTOME GLUCOSE REGULATION OF INSULIN SECRETION | NDUFA3, NDUFB8, SDHA, NDUFA1, NDUFS1, NDUFS8, CYC1, UQCRC1, ATP5O, NDUFS6, ATP5G1, ATP5J2, ATP5E, NDUFS2, NDUFB2, NDUFS3, NDUFB11, IDH3B, NDUFC1, NDUFA13, PDHB, RAPGEF3, IDH3G, PRKACA, ETFB, NDUFB3, SUCLG1, NDUFA4, NDUFB6, CS, COX8A, COX7C |
| REACTOME INTEGRATION OF ENERGY METABOLISM | PPP2R5D, NDUFA13, PDHB, NDUFA3, NDUFB8, RAPGEF3, SDHA, IDH3G, PRKACA, NDUFA1, NDUFS1, CYC1, NDUFB3, UQCRC1, ATP5O, ETFB, NDUFS6, ATP5G1, SUCLG1, CS, NDUFA4, COX8A, NDUFB2, COX7C, FASN, NDUFS3, IDH3B, NDUFC1 |
| KEGG ALZHEIMERS DISEASE | CDK5, NDUFA3, NDUFB8, SDHA, NDUFA1, UQCRFS1, NDUFS8, NDUFS1, CYC1, NDUFB3, UQCRC1, ATP5O, NDUFS6, PPP3CB, NDUFB6, NDUFA4, PSEN2, NDUFS2, ATP5E, ATP5G3, COX8A, COX7C, NDUFB2, NDUFS3, NDUFC1 |
| KEGG PARKINSONS DISEASE | NDUFA3, NDUFB8, SDHA, NDUFA1, UQCRFS1, NDUFS8, NDUFS1, CYC1, UQCRC1, ATP5O, NDUFB3, NDUFS6, NDUFB6, NDUFA4, NDUFS2, ATP5E, ATP5G3, COX8A, COX7C, NDUFB2, NDUFS3, NDUFC1 |
| KEGG HUNTINGTONS DISEASE | NDUFA3, POLR2L, NDUFB8, POLR2I, SDHA, NDUFA1, AP2A2, CYC1, NDUFS1, UQCRFS1, NDUFS8, AP2S1, NDUFB3, UQCRC1, ATP5O, NDUFS6, AP2B1, NDUFA4, NDUFB6, NDUFS2, ATP5E, ATP5G3, COX8A, COX7C, NDUFB2, NDUFS3, DCTN1, NDUFC1 |
| TIEN INTESTINE PROBIOTICS 24HR UP | ATOX1, FARP1, FKBP4, ADSL, LMAN2L, HSPE1, SHCBP1, CENPF, NUP85, HSPA14, GLRX5, DBI, ERCC3, NTAN1, ECHS1, PLXNA1, FDPS, SPAST, LRPAP1, GM2A, NDUFB2, DPP3, NUP205, LMNB2, EBP, NDUFC1, TPCN1, NDUFA13, PDHB, POLR2L, FOXM1, PSMB7, PRDX2, CALD1, NDUFB3, TUBG1, MSH6, ACAT2, NUDT1, SNRPD1, POLE2, TBL1X, SMYD2, NUP93, ATP5G3, H2AFV, TRAPPC4, QDPR |
| WONG EMBRYONIC STEM CELL CORE | SET, NDUFB8, PSMB6, CDK4, NTHL1, HSPE1, HSPA14, MID1IP1, KIF4A, ATP5O, PSMB5, MCM3, CLPP, SNRPD1, ECHS1, POLE2, CDC34, FDPS, GLO1, PDIA4, DPP3, NT5DC2 |
| MISSIAGLIA REGULATED BY METHYLATION DN | ITGB4, MSH6, CAD, GMPS, ACAT2, CDC25C, FOXM1, FASN, NDUFS3, KNTC1, EBP |
| REACTOME CELL CYCLE MITOTIC | KIF20A, PPP2R5D, POLA2, CDC16, CDK5RAP2, DBF4, PSMB6, CDK4, E2F1, SMC1A, PRKACA, PSMB7, PSMD4, ANAPC2, ANAPC5, CENPF, MNAT1, NUP85, CENPJ, PSMB2, TUBG1, PSMB5, MCM3, PPP2R5A, PSMD3, CDC25C, POLE2, ANAPC1, FZR1, KNTC1, KIF2C |
| REACTOME S PHASE | POLA2, PSMD7, ORC3L, PSMA2, PSMB6, CDK4, PSMB7, PSMD4, MNAT1, MCM4, PSMB2, PSMB5, MCM3, PSMD3, POLE2, POLE, PSME3, RPA1, FZR1, PSMB4 |
| FOURNIER ACINAR DEVELOPMENT LATE 2 | CAD, CLPB, CDC45L, FOXM1, C16ORF61, FKBP4, PREB, TXNDC5, SCD, NUP85, CDCA3, KIF4A, PSMB2, TUBG1, MCM3, MSH6, TIPIN, H2AFV, PRMT5, NUP205, NT5DC2, KIF2C, HMBS |
| REACTOME SYNTHESIS OF DNA | POLA2, PSMD7, ORC3L, PSMA2, PSMB6, PSMB7, PSMD4, MCM4, PSMB2, PSMB5, MCM3, PSMD3, POLE2, POLE, RPA1, PSME3, FZR1, PSMB4 |
| WHITEFORD PEDIATRIC CANCER MARKERS | NUDT1, LMNB2, POLE2, CENPF, CDK4 |
| SOTIRIOU BREAST CANCER GRADE 1 VS 3 UP | KIF4A, ORMDL2, CDC20, GMPS, NUDT1, TPX2, CDC45L, PFDN6, NUP93, C16ORF61, FOXM1, H2AFV, PRC1, TACC3, KIF2C |
| MITSIADES RESPONSE TO APLIDIN DN | |
| MORI IMMATURE B LYMPHOCYTE DN | H2AFV, PRC1, CDC45L, CDCA3 |
| ODONNELL TFRC TARGETS DN | KIF4A, KIF20A, CDC20, PLK1, POLE2, FOXM1, PRC1, TACC3, SHCBP1, SCD, CENPF, SURF1, BIRC5, ASPM |
| REACTOME DNA STRAND ELONGATION | |
| NCI ACTIVATION OF THE PRE REPLICATIVE COMPLEX | |
| KEGG DNA REPLICATION | |
| CROONQUIST NRAS SIGNALING DN | MCM3, CDC20, TPX2, CDC25C, UBE2C, PLK1, RAD51C, FOXM1, CSE1L, KIF2C |
| SCHLOSSER MYC AND SERUM RESPONSE SYNERGY | |
| REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | ATP5O, ATP5A1, ATP5I, ATP5C1, ATP5G1, ATP5J2, ATP5J, ATP5E, ATP5B |
| CAIRO HEPATOBLASTOMA CLASSES UP | |
| CORUM 55S RIBOSOME MITOCHONDRIAL | MRPL2, MRPS18A, MRPS16, MRPL35, MRPS11, MRPL49, MRPS10, MRPS14, MRPS35, MRPL48, MRPS22 |
| NCI ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | |
| REACTOME DNA REPAIR | |
| ZHANG RESPONSE TO CANTHARIDIN DN | |
| WELCSH BRCA1 TARGETS 1 DN | |
| KEGG BASE EXCISION REPAIR | |
| JEON SMAD6 TARGETS DN | |
| KEGG LYSINE DEGRADATION | |
| NCI FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | |
| KAUFFMANN DNA REPAIR GENES | |
| AMUNDSON GAMMA RADIATION RESPONSE | TACC3, UBE2C, CDC25C, PLK1, CENPA |
| KEGG NUCLEOTIDE EXCISION REPAIR | |