| Gene Set | Leading Edge Genes |
|---|
| HSIAO HOUSEKEEPING GENES | PRDX6, SET, GSTO1, RPL27, CASC3, RPS11, RPL24, SLC25A6, RPL38, ANXA2, YBX1, RPS6, ATOX1, RPS16, TXN, RPL18, CANX, RPL32, RPS9, RPL12, IQGAP1, LAMP1, PSMB5, BECN1, CST3, ECHS1, RPL14, RPL39, HSPB1, YWHAQ, DDT, CCT4, ATP6V1F, SEPT2, PTMA, CD81, ESD, RPL35, SLC25A3, CD151, VPS72, RPLP1, PSMB6, RPL11, RPS19, RPL36AL, RPS29, SF3B2, RPL28, GAPDH, COX8A, CSNK2B, RPL35A, COX7C, RPL7, TRIM28, PSMD7, HLA-DQB1, PLP2, GNAS, MGST2, GPX1, ANXA11, RPLP0, CTNNB1, IFITM1, ATP5A1, UBA52, RPS8, FYN, GNB2L1, RPL13A, RPL3, SOD1, ATP5C1, GNB1, H2AFZ, TMED10, RPS21, RPS5, LGALS1, S100A10, BUD31, HMGB1, RPL13, PSMB2, RPS7, RPL7A, VIM, WARS, OAZ1, COX4I1, SLC25A5, COX6A1, ATP5G3, RPLP2, PSAP, PSMB3, SNRPD2, HINT1, RPS15, NACA |
| MOOTHA VOXPHOS | NDUFA13, NDUFA3, UQCR, SURF2, SDHA, COX5B, NDUFA7, CYC1, NDUFA2, CYB5A, COX7B, NDUFA8, UQCRC1, NDUFA6, PET112L, NDUFS6, UCRC, COX4I1, NDUFB1, UQCRQ, NDUFB6, COX6A1, NDUFS2, NDUFAB1, COX7C, NDUFC1 |
| REACTOME ELECTRON TRANSPORT CHAIN | NDUFA13, NDUFA3, SDHA, COX5B, NDUFA7, CYC1, NDUFA2, COX7B, NDUFA8, UQCRC1, ETFB, NDUFA6, NDUFS6, NDUFB1, COX4I1, UQCRQ, COX6A1, NDUFS2, NDUFB6, NDUFAB1, COX7C, ETFA, NDUFC1 |
| KEGG PARKINSONS DISEASE | NDUFA3, SLC25A6, SDHA, COX5B, NDUFA7, CYC1, NDUFA2, COX7B, NDUFA8, UQCRC1, NDUFA6, UBE2G2, NDUFS6, COX4I1, NDUFB1, UQCRQ, NDUFB6, COX6A1, NDUFS2, NDUFAB1, COX7C, NDUFC1 |
| KEGG OXIDATIVE PHOSPHORYLATION | ATP6V1H, NDUFA3, SDHA, COX5B, NDUFA7, CYC1, NDUFA2, COX7B, ATP6V1G1, ATP6V0C, UQCRC1, NDUFA6, ATP6V0D1, NDUFS6, ATP5A1, COX4I1, NDUFB1, UQCRQ, ATP6V1D, NDUFB6, COX6A1, NDUFS2, NDUFAB1, COX8A, COX7C, NDUFB2, ATP6V1F, ATP5L, NDUFC1 |
| CORUM RESPIRATORY CHAIN COMPLEX I HOLOENZYME MITOCHONDRIAL | NDUFA13, NDUFS6, NDUFA3, NDUFB1, NDUFS2, NDUFB6, NDUFAB1, NDUFA7, NDUFA2, NDUFC1 |
| REACTOME GENE EXPRESSION | RPL10, RDBP, RPL27, CSTF2, RPL24, RPL38, YBX1, TARS, EIF2B5, RPS16, RPL18, SNRPF, RPL32, RPL12, POLR2G, EPRS, RAE1, RPL14, RPL39, NUP88, SSRP1, NUP188, RPL37, SNRPG, RPS20, MED6, SNRPD3, SF3B3, RPS19, RPL11, NHP2L1, PRPF8, FAU, RPS29, SF3B2, RPL7, U2AF1, NUP43, EIF5, POLR2C, MED12, RARA, RPLP0, PRPF4, POLR2J, UBA52, NFX1, PAPOLA, RPL5, RPS8, RPL13A, NUP205, GTF2H3, SF3A2, TCEB2, SFRS5, RPS5, RPS21, SNRPA, RPS7, EIF2B1, WARS, NR3C1, GTF2H1, RPLP2, NUP62, SNRPD2, RPS15, RXRB |
| DANG MYC TARGETS UP | RPL10, PCNA, RPL27, PRPS2, PSMB1, TXN, SNRPB, RPS16, HSPE1, RPL22, RPL32, UXT, DBI, TYMS, UBE2C, BAX, RPL5, HMGA1, CSTB, PTMA, RPS20, HSPA4, RPL3, SLC25A3, CAD, LTA4H, H2AFZ, SRM, SNRPD3, RPS5, SHMT1, RPL13, RPS19, RPS13, CCT5, PRDX3, GAPDH |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 13 | NDUFA13, POLE3, NDUFA3, UQCR, POLD3, TCEB2, MRPL23, MRPL35, CCND1, UBL5, PSME2, COX5B, S100A10, BUD31, NDUFA2, DAP, COX7B, TMEM93, DBI, PSMA6, HDDC2, LYRM2, OGFR, COX6A1, NDUFS2, NDUFAB1, SNRPG, EBP, NDUFC1 |
| CORUM RESPIRATORY CHAIN COMPLEX I LAMBDA SUBUNIT MITOCHONDRIAL | NDUFS2, NDUFA13, NDUFS6, NDUFA7, NDUFA2 |
| FOURNIER ACINAR DEVELOPMENT LATE 2 | PRPF40A, POLE3, CLPB, NOLC1, PLK1, ITGA3, MRPL17, TXN, GLT25D1, PRPS1, SNRPF, PREB, PRPF4, ARL4C, ANAPC5, GINS1, CKS1B, TNFRSF12A, EHD1, IGF2BP2, SMARCA4, RNASEH2A, NUP188, MAP4K4, NUP205, NIF3L1, RNASEN, HMBS, RAI14, TIMELESS, CAD, GNB1, SKP2, H2AFZ, C16ORF53, CDC45L, MRPL35, FOXM1, SF3B3, GEMIN6, PTPLAD1, ITGB5, HPS1, DHX15, PSMB2, DTL, LAMC2, PLOD3, MBNL1, NCAPG2, SPRY2, CALM1, CDCP1, PRDX3, SC65, IDI1, RFWD3, NT5DC2, XRCC3, KIF2C, BIRC5 |
| NCI REMOVAL OF LICENSING FACTORS FROM ORIGINS | PSMB2, PSMA6, PSMD14, PSMC5, PSMB5, PSMD7, UBA52, MCM5, CDT1, PSMB6, PSMB1, PSME2, PSMD9, PSMB3, PSMA7 |
| NCI ORC1 REMOVAL FROM CHROMATIN | PSMB2, PSMA6, PSMD14, PSMC5, PSMB5, PSMD7, UBA52, MCM5, CDT1, PSMB6, PSMB1, PSME2, PSMD9, PSMB3, PSMA7 |
| CORUM PA28GAMMA-20S PROTEASOME | PSMA6, PSMB2, PSMB5, PSMA2, PSMA5, PSMB6, PSMB1, PSMA4, PSMB7, PSMB3, PSMA7 |
| NCI VIF MEDIATED DEGRADATION OF APOBEC3G | PSMC5, PSMB8, PSMD7, PSMA2, PSMA5, TCEB2, PSMB6, PSMB1, PSMA4, PSME2, PSMB7, PSMD9, PSMA7, PSMD14, PSMA6, PSMB2, PSMB5, UBA52, PSMB10, PSMB3 |
| NCI SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE | PSMC5, PSMB8, PSMD7, PSMA2, PSMA5, PSMB6, PSMB1, PSMA4, PSME2, PSMB7, PSMD9, PSMA7, PSMD14, PSMA6, PSMB2, PSMB5, UBA52, MCM5, PSMB10, PSMB3 |
| PELLICCIOTTA HDAC IN ANTIGEN PRESENTATION DN | PSMD14, PSMB2, PSMA6, PSMC5, PSMB5, DERL1, PSMD7, PSMB6, TAPBP, TAP2, PSME2, HLA-B, KDELR1, HLA-C, PSMA7 |
| CORUM NOP56P-ASSOCIATED PRE-RRNA COMPLEX | RPL10, RPL27, RPS11, RPL24, NOLC1, YBX1, RPS6, RSL1D1, PWP1, RPLP0, RPS16, RPL18, RPL22, RPL32, RPL12, RPS9, SCYL2, RBM28, RPL14, EBNA1BP2, RPL39, RPL5, RPS8, RPL13A, RPL3, RPL35, HIST1H1D, RPLP1, RPL13, RPL11, NHP2L1, RPS7, RPL7A, RPS13, RPS29, SLC25A5, RPL28, RPL15, RPLP2, RPL35A, RPL7, U2AF1, RPS15 |
| PENG LEUCINE DEPRIVATION DN | OGFR, SRM, PDIA4, LRRC32, HSPE1, PSMA7, BST2, HSPA4, EMP3, AHSA1 |
| CORUM RESPIRATORY CHAIN COMPLEX I INTERMEDIATE VII/650KD MITOCHONDRIAL | |
| HONMA DOCETAXEL RESISTANCE | RPL38, IFI6, MRPL17, SQRDL, GNB2L1, MRPS6, S100A10, COX7C, MX1 |
| CORUM 18S U11/U12 SNRNP | |
| NCI TRANSCRIPTION COUPLED NER TC NER | GTF2H3, GTF2H1, ERCC6, POLR2C, ERCC5, POLR2J, POLR2G, MNAT1 |
| NCI CYTOSOLIC TRNA AMINOACYLATION | |
| REACTOME NUCLEOTIDE EXCISION REPAIR | GTF2H3, GTF2H1, PCNA, POLD1, POLR2G, POLR2J |
| NCI GLOBAL GENOMIC NER GG NER | |
| NCI FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX | GTF2H3, GTF2H1, ERCC6, POLR2C, ERCC5, POLR2J, POLR2G, MNAT1 |
| REACTOME DNA STRAND ELONGATION | GINS1, PCNA, GINS4, MCM5, POLD1 |
| LUI THYROID CANCER CLUSTER 3 | |
| REACTOME METABOLISM OF PROTEINS | |
| LIAO METASTASIS | |
| NCI DUAL INCISION REACTION IN GG NER | |
| NCI UNWINDING OF DNA | |
| BONOME OVARIAN CANCER POOR SURVIVAL DN | GLT25D1, EHMT2, GRK6 |
| NCI FORMATION OF INCISION COMPLEX IN GG NER | |
| REACTOME DUAL INCISION REACTION IN TC NER | GTF2H3, GTF2H1, ERCC6, POLR2C, ERCC5, POLR2J, POLR2G, MNAT1 |
| CHNG MULTIPLE MYELOMA HYPERPLOID UP | RPL35, RPL24, RPLP1, RPS6, RPS16, RPL18, RPL32, RPS9, RPS19, RPL7A, UBA52, RPS13, RPL14, RPLP2, RPL15, RPL28, RPL37, RPL35A, RPL29, RPL13A, RPS15, KLK3 |
| REACTOME DUAL INCISION REACTION IN GG NER | |
| CORUM 12S U11 SNRNP | |
| REACTOME UNWINDING OF DNA | |
| NCI DUAL INCISION REACTION IN TC NER | GTF2H3, GTF2H1, ERCC6, POLR2C, ERCC5, POLR2J, POLR2G, MNAT1 |
| CORUM NCOR1 COMPLEX | |
| NCI MRNA SPLICING MINOR PATHWAY | NHP2L1, PRPF8, ASCC3L1, SNRPD3, SF3B2, SF3B3, SNRPG, SNRPF, SNRPD2, POLR2C, POLR2J, POLR2G |