| Gene Set | Leading Edge Genes |
|---|
| PUJANA BRCA1 PCC NETWORK | POLA1, CDC16, HMGCR, TMPO, SMNDC1, PSMA2, PPP1CC, YY1, SLBP, PSMA4, FH, ACTR3, TIPRL, POLR2G, CKS1B, NCAPH, LSM3, GSR, COX7A2L, ARPC2, CCT4, PTMA, BUB3, SNRPE, EIF4E2, ASH2L, ACVR1B, NUP155, UBE2G1, SUMO1, HBXIP, ME2, RPL19, PRKRA, COPB1, VBP1, PRDX3, PRKRIR, PFAS, SUB1, CCNB1, TIMM17A, RBM34, YARS, NDUFS1, TOPBP1, RCOR1, PARN, CBFB, CDC23, TCP1, SNX4, PPIH, COX6C, HTRA2, DLD, PAICS, INVS, PSMB2, HMGN1, FADS1, NONO, GTF2H1, NPM3, ATXN10, DARS, PRIM1, MYCBP, SET, COPS5, ILF2, NOLC1, IARS2, MRPL3, RGS10, PSMA3, EIF2S1, IGBP1, GINS1, ATP5O, TAF9, TBCE, PPP2R5C, PABPC1, SUMO2, IMPDH2, GTF2E2, LARP7, ZNHIT3, DPM1, GNPAT, XPNPEP1, PSMB7, PHF20, NFYB, SMC3, CCT5, GTF2A2, FDFT1, XRCC5, EIF5, KIF2C, C6ORF130, NNT, ATG12, RAD51C, DAP3, NUP133, COX7B, ANXA13, TBCA, ZNF259, CYB5B, FRG1, TFDP1, PSMC2, UBE2I, MFAP1, LSM5, OXA1L, ADNP, SNRPB2, PSIP1, CCNB2, PCMT1, MSH6, CLINT1, SLC25A5, PMS1, ANP32A, ZMPSTE24, C14ORF143, ABI1, FOXA2, HSPD1, TOP2B, RPS25, BCAS2, MXRA7, CENPA, PSMB1, POLR2B, TXN, MTIF2, PARP2, ZNF207, DBI, UPF2, GMPS, TMEM106C, CHEK1, MELK, SNRPG, PPM1A, DLAT, TCEB1, UBTF, CSE1L, MPHOSPH6, CCNG1, CCT2, TAF12, SSB, ACAT2, ATF2, RPA1, TOMM34, EEF1E1, IARS, HMGN3, NPM1, ERH, EEF1B2, ZWINT, DKC1, PRPS2, TRIM14, GART, GALNT1, TRIAP1, PSME2, NCBP2, TOP2A, SLC20A1, ARCN1, CNOT1, DDX18, C7ORF44, CCT8, C10ORF28, MFN1, ATP5J, SSBP1, USP10, CASP2, AK2, SERBP1, SRP72, UBE2L3, APITD1, MTAP, TMEM5, H2AFZ, HPRT1, RBBP7, ATIC, RFC4, OIP5, MAPRE1, HIST1H4C, GOSR1, RPL30, NCBP1, UBE2D2, BTF3, HDAC2, CCNC, PRDX1, ANP32B, MRPS31, EXOSC10, NCAPD2, RPL24, CCBL1, BUB1, GTF3A, CCT3, GTF3C2, ASNS, HSPE1, RFC5, IQCB1, EXOSC8, PSMD10, MRPS18B, CDK7, ECD, MBD2, FDPS, COPS3, PMPCB, CNIH, CHEK2, CRLF3, PSMA5, KIAA0922, NGDN, SHFM1, IMMT, AGPS, TRIP13, M6PR, DUT, INSIG1, TCEA1, RPL36AL, PCCB, PTTG1, UNG, ALDH5A1, TARDBP, CLPX, SCYE1, STARD7, AP3S1, RGS19, SNW1, UQCRH, DBF4, PAK2, KARS, STMN1, RAN, PWP1, AURKA, ADSL, ANAPC5, CENPF, C6ORF62, MSH2, ALG8, WEE1, PIGF, CKS2, ZBTB24, UQCRC2, TINP1, CDK2, ZNF22, SSR1, PSMC6, BET1, MTR, TOR1A, BUB1B, KIAA0196, HSP90AA1, RRM1, TIMM8A, PIGB, RPA3, ACTR2, UBE2N, NAP1L1, NDUFB3, PTDSS1, GRIP2, YWHAB, LBR, CUL1, DHX9, DNAJC7, RAD51AP1, HAT1, RNGTT, WDR67, H2AFV, SNRPD2 |
| BLALOCK ALZHEIMERS DISEASE DN | SCCPDH, BCAS2, PFN2, HSPD1, MGST3, DNM1L, RPN2, GLT8D1, TXN, PCCA, POLR2B, FH, ACTR3, ZNF207, AASDHPPT, ADH5, POLR2G, SAP18, ARPC5, DDX1, LSM3, NFYC, ATP6V1D, NDUFS2, ARPC2, COX7A2L, CCT4, ESD, DLAT, ASH2L, PIK3R4, CSE1L, SCP2, PAM, UBE2G1, WDR7, SUMO1, TOMM20, OGT, HBXIP, CCT2, NDUFS4, SSB, VBP1, PRDX3, DCTN2, SHANK2, EEF1E1, IARS, DYNLL1, PFKM, MGEA5, FKBP1B, SUB1, GLRB, COPS8, TIMM17A, NCBP2, FGF13, BAG5, RPE, ARCN1, CDS2, RCOR1, AP4S1, WRB, ITGB1BP1, PDIA6, ACP1, DNAJC8, ATP5J, SSBP1, SNX4, SRP54, ARPC1A, USP10, RNF14, SERBP1, COX6C, SRP72, TSPAN7, ARL1, ATP6V1E1, HTRA2, DLD, TMEM5, TSG101, PPT1, HPRT1, UBE2B, ATIC, RAB11A, CD59, PSMB2, PGM1, DYNC1I2, PPP3CB, COX7A2, SLC25A14, CALM1, EIF1B, UROS, ATXN10, DARS, ATP5L, DYNLT3, USP33, COPS5, CRYZ, NOLC1, GBAS, HSP90AB1, PRKAR1A, NARS, CCT3, SLC35A1, MRPL3, ATP5H, HSPE1, CYC1, RFC5, EIF2S1, ATP5O, PSMB5, PSMD10, UGP2, COX6B1, CDK7, TAF9, PMPCB, SUCLA2, PPP2R5C, STAMBP, SUMO2, HRSP12, EPHA4, PAPSS1, PSMA5, FARS2, ZNHIT3, PIAS1, LAPTM4B, C11ORF58, TTC1, SHFM1, SCAMP1, STAT1, NHP2L1, TXNDC9, PCCB, CCT5, RCHY1, GTF2A2, SMYD2, ALDH5A1, ELAVL4, C18ORF10, DCTN6, PEX19, CAP1, EIF5, PON2, FBXL2, AP3S1, SC5DL, NNT, PPP1R7, SNX3, RPP30, UQCRH, CDC40, RAD51C, PEX11B, APP, ATP2B1, TCEAL1, NDUFB5, GALC, ENC1, COX7B, TBCA, MDH1, PPID, MSH2, TRIM37, ALG8, NQO1, CKS2, TFDP1, UQCRC2, PAFAH1B1, PCTK2, PSMC2, FHL1, SSR1, LSM5, PSMC6, BET1, EBP, TOR1A, RSU1, ATP5C1, ATRN, ATP6V1C1, HSP90AA1, PPP2CA, BRE, ACTR2, ATP8A2, MAOA, ZNF204, NDUFB3, MTMR4, SLC9A6, PTDSS1, YWHAB, PCMT1, CUL1, C5ORF13, REEP5, COX4I1, SLC25A5, OAT, ATP5G3, H2AFV, SNRPD2, KDELR2 |
| DODD NASOPHARYNGEAL CARCINOMA DN | POLA1, HSPD1, TMPO, PSMA2, RPN2, CENPA, SLBP, PSMA4, GNPDA1, CALU, ZNF207, TIPRL, ADH5, CKS1B, NCAPH, SFRS7, CHEK1, YWHAQ, MELK, SNRPG, RBM9, BUB3, SNRPE, EIF4E2, TCEB1, CSE1L, NUP155, CCNG1, SUMO1, CCT2, ME2, TPX2, SLC25A13, GPSM2, MLLT11, PMP22, UMPS, EEF1E1, CSTF1, RBMX, IARS, DKC1, ZWINT, SUB1, CCNB1, RBM34, STX6, YARS, RPE, TOPBP1, TOP2A, DDX18, C7ORF44, CCT8, SSBP1, SUPT7L, AK2, SRP72, DPYSL2, RAI14, PAICS, H2AFZ, COPS2, HPRT1, SPAG5, ATIC, RFC4, C3ORF63, OIP5, MAPRE1, ATP6V1B2, PSMB2, TTK, CPOX, PLAGL2, NCBP1, CDC25C, NONO, HDAC2, DARS, PRIM1, BUB1, NOLC1, SLC39A14, CCT3, MRPL3, TCF12, CYC1, RPL22, RFC5, ASCC3, GPR137B, ADIPOR2, GINS1, MCM6, TBCE, STAMBP, LAMB1, CHEK2, TMEM97, HRSP12, CCT6A, PRNP, UTP18, NFYB, C11ORF58, IMMT, DHX15, THOC1, DPY19L4, STAT1, SOCS5, PTTG1, UNG, RCHY1, IDH1, XRCC5, CBX1, KIF2C, NNT, SEPHS1, DBF4, RAD51C, STMN1, RAN, PWP1, AURKA, ADSL, NUP133, CENPF, MSH2, MTRR, CKS2, ZBTB24, GRSF1, TNPO1, LSM5, MTR, BUB1B, FXR1, FANCG, RRM1, ADNP, MTMR4, CCNB2, MSH6, CUL1, C5ORF13, PGK1, PMS1, ATP5G3, RAD51AP1, PPAT, QDPR, UBE3A |
| KINSEY TARGETS OF EWSR1 FLII FUSION UP | POLA1, POLE3, HSPD1, TMPO, PVRL3, CENPA, SLBP, FH, ZNF207, AASDHPPT, COQ9, SDHC, ADH5, ARPC5, NCAPH, NFYC, DUS4L, SSRP1, CHEK1, ARPC2, MELK, PTMA, CUL3, ESD, DLAT, TCEB1, FADS3, NUP155, PSMD1, UBE2G1, CCT2, TMED2, ME2, TPX2, MDC1, PRDX3, GPSM2, RPA1, UMPS, CSTF1, DKC1, ZWINT, PRPS2, GART, CCNB1, BAG5, RPE, RCOR1, TOP2A, SLC20A1, CNOT1, PPP1R16B, WRB, DDX18, ACP1, TCP1, PLS1, SRP54, USP10, AK2, SERBP1, SRP72, BLM, APITD1, PAICS, TMEM5, PRUNE, RFC4, OIP5, MAPRE1, HIST1H4C, COIL, TTK, NCBP1, CDC25C, SLC25A14, CALM1, UVRAG, NONO, CCNC, CRKL, DARS, PRIM1, PGD, SET, COPS5, MTDH, MAGOH, CRYZ, BUB1, HSP90AB1, SERP1, RFC5, GINS1, GYG2, PSMD10, MCM6, NUP88, COPS3, TBCE, SUCLA2, VAMP3, PPP2R5C, CHEK2, TMEM97, HRSP12, CRLF3, XPNPEP1, NFYB, C11ORF58, SMC3, SEPT10, DHX15, TRIP13, TCEA1, PTTG1, GTF2A2, KIAA0895, XRCC5, KIF2C, SQLE, PPP1R7, SNX3, SEPHS1, PLP2, DBF4, RAD51C, PAK2, AURKA, CDC2, PRPS1, ICMT, CENPF, SIPA1L1, STAU2, PPID, MSH2, CYB5B, WEE1, TFDP1, ZW10, GRSF1, UQCRC2, CDK2, EXOSC9, EXOSC2, BUB1B, FANCG, HSP90AA1, RRM1, GALK2, ACTR2, MTMR4, CTH, CCNB2, MSH6, CUL1, PGK1, SRR, ANP32A, RAD51AP1, CDYL, PPAT, UBE3A, KDELR2 |
| CASORELLI ACUTE PROMYELOCYTIC LEUKEMIA DN | PGD, HMGCR, DLEU1, HSPD1, RAB3GAP1, HSP90AB1, NOLC1, DNM1L, ARID5B, CENPA, INPP4B, PTK2, ACTR3, CYC1, EIF2S1, SCD, ADIPOR2, GINS1, NCAPH, CKS1B, PSMB5, TAF15, TMEM106C, VCL, DUS4L, FDPS, ACSL3, CHEK1, SSRP1, MELK, RBM9, BUB3, CHEK2, TMEM97, DLAT, EIF4E2, ASH2L, POLD3, CSE1L, NUP155, HTATIP2, EED, LAPTM4B, SUMO1, DHX15, TRIP13, M6PR, SC4MOL, NHP2L1, INSIG1, ACAT2, HADHA, CCT5, FZD6, FDFT1, XRCC5, GPSM2, TARDBP, SMC4, HSD17B4, GLUL, KIF2C, SQLE, NNT, PFKM, ELOVL6, DKC1, PTRF, ZWINT, CCNB1, AURKA, CDC2, RPE, BLVRA, TOP2A, CENPF, GNAI1, NSDHL, PDK3, DDX18, PPID, DNAJC8, C7ORF44, PDIA6, STIL, ST7, PLS1, SRP54, SNX4, SERBP1, SSR1, NEK9, EBP, EXOSC2, BUB1B, RMND5B, PAICS, RPS4Y1, SCRN1, HSP90AA1, MLLT3, SPAG5, MAPRE2, PIR, ATIC, RFC4, ACTR2, COIL, MAOA, FHL2, CCNB2, SRI, HEXIM1, NCBP1, CDC25C, PGK1, FADS1, DHX9, NONO, ACLY, UROS, ELOVL5, KDELR2 |
| STEIN ESRRA TARGETS | NNT, SLC31A1, RGS19, PFKM, ALDH3A2, MGST3, SLC39A14, PRPS2, TRIM14, ST3GAL5, ETFDH, TIMM17A, AURKA, AK1, ASNS, GNPDA1, NDUFB5, FH, CALU, NDUFS1, COX7B, ATP5O, MDH1, C7ORF44, ATP5G1, MXD4, MUT, UGP2, ATP5J, PLS1, RNF14, NDUFS2, UQCRC2, DCTD, SUCLA2, RBM9, DECR1, EBP, EXOSC2, LAMB1, DLD, FZD2, DLAT, OXA1L, PPIC, TIMM8A, HTATIP2, B3GNT1, ACAA2, IMMT, NAP1L1, ANXA6, ACAT1, MSH6, NDUFS4, SSB, DSCR3, ATP5G3, WDR67, KIAA0494, NPM3, MID1, STARD7, ATP5L |
| STEIN ESRRA TARGETS UP | NNT, SLC31A1, PFKM, ALDH3A2, MGST3, TRIM14, ST3GAL5, ETFDH, TIMM17A, AURKA, AK1, ASNS, NDUFB5, FH, CALU, NDUFS1, COX7B, ATP5O, MDH1, WWC1, C7ORF44, ATP5G1, MUT, UGP2, ATP5J, RNF14, NDUFS2, UQCRC2, SUCLA2, DECR1, EBP, DLD, DLAT, OXA1L, PPIC, TIMM8A, HTATIP2, ACAA2, IMMT, ANXA6, ACAT1, NDUFS4, DSCR3, ATP5G3, WDR67, NPM3, ATP5L |
| RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED UP | GPNMB, HSPD1, NOLC1, TMPO, DNM1L, SLC39A14, PSMA2, ASNS, MTIF2, CALU, FH, PSMA3, TIPRL, UBE2V2, EIF2S1, SCD, GINS1, P4HA1, CKS1B, ABCD3, GMPS, TAF9, GSR, IDE, CHEK1, BUB3, TMEM97, ZNF146, PSMA5, TCEB1, CSE1L, NUP155, LAPTM4B, SMC3, SCAMP1, SEPT10, AGPS, ANXA1, ME2, C18ORF10, TUSC3, GPSM2, GMFB, APC, P4HA2, KIF2C, CARS, CHRNA5, NNT, ZWINT, ELOVL6, DBF4, SUB1, CCNB1, RAD51C, COPS8, GART, STMN1, TIMM17A, RAN, AURKA, CDC2, NCBP2, ADSL, GALC, TOPBP1, CENPF, ENC1, GNAI1, C7ORF44, ACP1, CBFB, STIL, CCT8, YTHDF3, SSBP1, CKS2, SSR1, EXOSC9, BUB1B, RAI14, SAR1A, FXR1, ITGB1, PAICS, H2AFZ, ATP6V1C1, RRM1, ATIC, RFC4, ACTR2, TRIP11, MSH6, DHX9, PMS1, SGCE, DCUN1D4, RAD51AP1, HAT1, PPAT, NPM3 |
| SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN DN | SNUPN, GPNMB, CDC16, CRYZ, HSP90AB1, NOLC1, PSMA2, RPN2, PPP1CC, PSMB1, POLR2B, MTIF2, ZNF207, PSMA3, PRCP, ADH5, GPR137B, EIF2S1, RBM5, ATP5O, ARPC5, CLEC2B, MAN2A1, ATP6V1D, UGP2, SSR2, TAF9, YWHAQ, COX7A2L, TSPAN31, CCT4, CNIH, COPB2, GLG1, PDCD6, C22ORF28, PPM1A, MCL1, CRLF3, ASH2L, PSMA5, FARS2, SCP2, XPNPEP1, NFYB, PIAS1, TTC1, CD46, GRK5, RNF13, TOMM20, ATP6V1G1, M6PR, TRAM1, CCT2, TXNDC9, NDUFS4, CNOT2, HADHA, VBP1, DCTN6, PRDX3, PEX19, GMFB, EIF5, CAP1, RABIF, SNX3, ALDH3A2, PEX11B, TIMM17A, PWP1, DAP3, YARS, SPTLC1, LIPA, GALC, IFITM1, DAZAP2, TRIM13, TM9SF2, CDC23, ST13, ZNF148, C19ORF2, GRSF1, XBP1, SRP72, ZNF22, MFAP1, ARL1, BET1, CTDSP2, ATP6V1E1, YTHDC1, DLD, CREBL2, PPT1, BRE, TMED10, ORC4L, CAT, TCEB3, RPA3, MAPRE1, ACTR2, CD59, UBE2N, ATP6V1B2, SNRPB2, PTDSS1, NSF, CUL1, PGM1, PPP3CB, UBE2D2, SLC25A5, DRG1, DSCR3, ANP32A, RNGTT, CDYL, CCNC, ATXN10, LAPTM4A |
| ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE UP | SET, SERPINB1, RPS25, ILF2, CETN2, HSP90AB1, MGST3, IARS2, GTF3C2, SERP1, TIPRL, GPR137B, SDHC, IGBP1, CKS1B, PSMB5, GMPS, LSM3, MRPS18B, SSR2, TBCE, CNIH, COPB2, PAPSS1, TCEB1, FARS2, RGS5, PPIC, GNPAT, MRPL40, GNG5, SMC3, TOR1AIP1, CCT2, NHP2L1, RPL36AL, TAF12, ACBD3, GTF2A2, IDH1, MDC1, VBP1, PEX19, GMFB, RPA1, P4HA2, EEF1E1, DYNLL1, AP3S1, AURKA, RBM34, NUP133, NDUFB5, BLVRA, C6ORF62, PPID, WRB, ACP1, PDIA6, TOM1L1, CCT8, CKS2, TFDP1, HAX1, SSR1, MFAP1, PSMC6, ARL1, KIAA0196, LPGAT1, TSG101, H2AFZ, HPRT1, ATRN, OXA1L, TMED10, GGPS1, RBBP7, PIR, TIMM8A, RFC4, SERTAD2, RPA3, PIGB, MAPRE1, UBE2N, NDUFB3, PSMB2, RPL30, MSH6, BTF3, DRG1, COX7A2, IK, KDELR2 |
| BENPORATH MYC MAX TARGETS | MYCBP, SLC31A1, CDC16, MAGOH, RPS25, TMPO, PSMB1, GLT8D1, YY1, TCF12, SERP1, NDUFA1, ACTR3, EIF2S1, SCD, USP4, CALM2, IGBP1, GINS1, PSMB5, DDX1, PSMD10, MAN2A1, ATP6V1D, SFRS7, COPS3, COX7A2L, HRSP12, EIF4E2, ASH2L, PSMA5, VPS52, FADS3, DPM1, AMD1, MPHOSPH6, GNPAT, MRPL40, PSMB7, PIAS1, AGPS, TRIP13, HBXIP, M6PR, SSB, GNS, PRKRA, ARL6IP5, EEF1E1, ZNF35, PSMC5, PPP1R7, SNX3, ATG12, MGEA5, PRPS2, PEX11B, PWP1, ASAH1, SYPL1, NDUFB5, NDUFS1, TOPBP1, NDUFA6, AP4S1, PET112L, MDH1, MSH2, ZNF259, CCT8, PIGF, SRP54, CKS2, UQCRC2, HAX1, MFAP1, ARL1, HTRA2, LTA4H, ATP5C1, PPP1R12A, TMEM5, CREBL2, H2AFZ, COPS2, PPP2CA, TMED10, SPAG5, TCEB3, MAPRE2, MAPRE1, COIL, PTDSS1, PCMT1, SRI, NCBP1, RASA1, DRG1, PMS1, ZMPSTE24, RAD51AP1, ATXN10, DDX17 |
| TARTE PLASMA CELL VS PLASMABLAST DN | MYCBP, COPS5, TOP2B, TMPO, PSMA2, NARS, CENPA, MRPL3, ASNS, TXN, HSPE1, FH, PSMA3, EIF2S1, DBI, GINS1, ATP5O, CKS1B, ABCD3, CLEC2B, FDPS, CCT4, SNRPG, GLDC, SUMO2, TMEM97, CLIC1, GGH, PSMA5, TCEB1, CSE1L, MPHOSPH6, SUMO1, TRIP13, DUT, ANXA6, CCT2, CCT5, VBP1, FDFT1, RPA1, EIF5, KIF2C, PSMC5, NNT, PRPS2, UQCRH, CCNB1, GALNT1, GART, PAK2, TIMM17A, PWP1, PSME2, YARS, NDUFS1, TOPBP1, TOP2A, COX7B, ZNF410, TCP1, ATP5J, CKS2, UQCRC2, COX6C, SSR1, OSTF1, UBE2L3, EBP, EXOSC2, PAICS, HPRT1, RRM1, ATIC, RFC4, SNRPB2, PSMB2, CPOX, LBR, DNAJC7, OAT, ANP32A, HUWE1, SLC39A7, PRIM1 |
| NUYTTEN EZH2 TARGETS DN | SET, RDBP, NCAPD2, BUB1, TMPO, CPS1, PPP1CC, GLT8D1, CENPA, CTSL2, INPP4B, COCH, PTK2, RFC5, POLR2G, NCAPH, CKS1B, NLE1, SP3, EXOSC8, NRXN3, EIF4EBP2, MRPS18B, ENTPD4, YWHAQ, SSRP1, CCT4, PTMA, CUL3, VPS26A, BUB3, TMEM97, PPM1A, IMPDH2, HSBP1, CSE1L, NUP155, GNPAT, UTP18, SMC3, CD46, SRF, DPY19L4, CCT2, TPX2, PTTG1, SPA17, MKRN1, SLC26A2, MDC1, TBL1X, TSPAN6, PEX19, PPM1B, UMPS, KIF2C, DKC1, ZWINT, ALDH3A2, PRPS2, GART, CCNB1, RAD51C, PAK2, AURKA, PRPSAP1, TRIAP1, TCEAL1, SYPL1, ARCN1, TOP2A, TOPBP1, CENPF, CNOT1, DAZAP2, TRIM13, DNAJC8, STIL, TRIM37, CYB5B, WEE1, TFDP1, SPAST, BANF1, UBE2I, CDC42, ARL1, BLM, LSM5, EXOSC2, APITD1, ITGB1, LPGAT1, CREBL2, HPRT1, ATP6V1C1, FANCG, PRUNE, AZI1, SPAG5, DDHD2, UBE2B, RFC4, RPA3, SERTAD2, OIP5, GLCE, GALK2, HIST1H4C, TCF7L2, MTMR4, CCNB2, LBR, PPP3CB, FADS1, ANP32A, KLHL9, RAD51AP1, GTF2H1, C14ORF143, H2AFV, WDR67, HDAC2, IK, PRIM1, KCNK1 |
| ACEVEDO LIVER CANCER UP | SERPINB1, CDC16, SMNDC1, RIN2, RPN2, CALU, ACTR3, CFHR2, AASDHPPT, TIPRL, UBE2V2, SDHC, PSMA6, CKS1B, ARPC5, GMPS, LSM3, COPB2, TCEB1, CCNG1, RGS5, GNG5, PAK1, CD46, TOR1AIP1, TAF12, ANAPC13, MDC1, VBP1, P4HA2, EEF1E1, SUB1, ANKMY2, NCBP2, RBM34, TOPBP1, WRB, TOM1L1, PDIA6, ACP1, SRP54, SNX4, SRP72, SAR1A, CREBBP, PPT1, H2AFZ, GGPS1, RBBP7, PIR, RFC4, TRIP12, PLS3, VIM, SLC25A14, UVRAG, HDAC2, EIF1B, C9ORF3, ELOVL5, DYNLT3, ILF2, CETN2, GBAS, HSP90AB1, PRKAR1A, IARS2, CCT3, SERP1, GTF3C2, GPR137B, IGBP1, PSMD10, SSR2, VPS26A, PALLD, LAMB1, SUMO2, TMCO1, OCRL, PAPSS1, LARP7, HBP1, DPM1, FARS2, PPIC, GNPAT, SMC3, PIAS1, IMMT, DHX15, ACBD3, SPA17, PEX19, GMFB, PON2, C6ORF130, ZFYVE26, AP3S1, POLD4, SEPHS1, UQCRH, AURKA, NDUFB5, NUP133, BLVRA, LIPA, COX7B, ATP6V1A, C6ORF62, MICA, VPS8, PPID, ZNF259, YTHDF3, CKS2, UQCRC2, MFAP1, SSR1, BET1, KIAA0196, ABLIM3, LPGAT1, TMED10, TIMM8A, SNX2, PIGB, RPA3, SERTAD2, UBE2N, SLC9A6, KLHL9, IK, KDELR2 |
| HORIUCHI WTAP TARGETS DN | SC5DL, POLA1, SEPHS1, NCAPD2, HMGCR, EEF1B2, BUB1, TMPO, PLP2, CCNB1, CENPA, AURKA, RFC5, TOP2A, COX7B, PEX13, CKS1B, ABCD3, GSR, CKS2, FDPS, MELK, BUB3, BUB1B, TMEM97, PPM1A, IMPDH2, PAICS, DLAT, HSP90AA1, CAT, RRM1, OIP5, C11ORF58, HIST1H4C, SEPT10, NAP1L1, TRIP13, CCNB2, LBR, ACAT2, UNG, PTTG1, SLC25A5, RAD51AP1, FDFT1, H2AFV, GMFB, CCNC, CDH2, ATXN10, KIF2C |
| MANALO HYPOXIA DN | NOLC1, ELOVL6, DKC1, ZWINT, RPP30, DBF4, GART, CDC2, GNPDA1, PRPS1, YARS, PARP2, AASDHPPT, RFC5, EIF2S1, GINS1, PET112L, NLE1, EXOSC8, DDX18, PDCD2, STIL, MCM6, GPD1L, IDE, MELK, EXOSC2, APITD1, DLAT, TMEM5, FANCG, CSE1L, RRM1, MRPL40, ATIC, OIP5, TRIP13, ID1, ACAT2, TPX2, RAD51AP1, PPAT, EEF1E1, UMPS, IARS |
| WEST ADRENOCORTICAL TUMOR UP | HMGCR, POLE3, BUB1, TMPO, RPN2, TXN, PSMA3, RFC5, SCD, UBE2V2, TMEM106C, TAF9, FDPS, MELK, BUB3, TMEM97, CCT6A, PSMB7, KIAA0922, GNG5, VPS41, MLF1, SC4MOL, TXNDC9, ACAT2, TPX2, PTTG1, TMED9, FDFT1, DCTN2, P4HA2, KIF2C, IARS, SQLE, HDAC1, SC5DL, NNT, ZWINT, ELOVL6, CCNB1, FBN2, ANKMY2, AURKA, CDC2, SPTLC1, ICMT, TOP2A, SLC20A1, CENPF, MICA, CDC23, TCP1, TNPO1, ANXA4, PSMC2, LSM5, PSMC6, EBP, BUB1B, H2AFZ, NR1H4, PIR, MAPRE1, ACTR2, CLINT1, CDC25C, ZMPSTE24, RNGTT |
| WELCSH BRCA1 TARGETS 1 UP | HDAC1, SEC23A, SERPINB1, PRKAR1A, COPS8, TCEAL1, NDUFS1, LIPA, TOP2A, PRCP, GNAI1, SDHC, CALM2, ABCD3, MICA, WRB, TM9SF2, NFYC, CKS2, ARPC1A, ZNF148, ANXA4, VAMP3, SSR1, PPP2R5C, NPC2, TSG101, COPS2, ALDH7A1, PPIC, PAM, SCAMP1, CD46, AGPS, ID4, TRAM1, STAT1, ANXA1, TAF12, IDH1, HMGCL, KDELR2, KIF2C, HMGN3 |
| REACTOME CELL CYCLE MITOTIC | PSMC5, CDC16, POLA1, CETN2, BUB1, ZWINT, PSMA2, DBF4, CCNB1, PPP1CC, CENPA, PSMB1, AURKA, PSME2, PSMA4, NUP133, RFC5, CENPF, GINS1, PSMA6, CKS1B, PSMB5, PSMD10, CDC23, WEE1, CDK7, TFDP1, CDK2, PPP2R5C, BUB3, PSMC6, BUB1B, APITD1, UBE2D1, PSMA5, PPP2CA, HSP90AA1, PSMC1, PSMB7, RFC4, RPA3, SMC3, MAPRE1, PSMB2, CCNB2, CUL1, PTTG1, DYNC1I2, DCTN2, KIF2C, DYNLL1, PRIM1 |
| SHEDDEN LUNG CANCER POOR SURVIVAL A6 | SEC23A, PFN2, BUB1, NOLC1, SMNDC1, DNM1L, CENPA, SLBP, CTSL2, MTIF2, ACTR3, SCD, UBE2V2, GINS1, NCAPH, CHEK1, MELK, BUB3, PYGL, EIF4E2, PSMA5, CSE1L, XPNPEP1, TRIP13, NDUFA9, NMU, TPX2, PTTG1, CCT5, GPSM2, KIF2C, CHRNA5, SEPHS1, ZWINT, ELOVL6, CCNB1, DBF4, STMN1, SNX7, RAN, AURKA, ATP2B1, CDC2, PRPS1, TOP2A, CENPF, PPID, ACP1, C7ORF44, PDCD2, TCP1, TFDP1, CKS2, ZNF248, EXOSC2, BUB1B, SAR1A, UBE2D1, PAICS, H2AFZ, SPAG5, TIMM8A, RFC4, OIP5, PSMB2, CCNB2, PCMT1, MSH6, HEXIM1, NCBP1, HAT1, RAD51AP1, HDAC2, CDYL, PPAT, DARS, PRIM1 |
| KEGG PARKINSONS DISEASE | NDUFS5, HTRA2, ATP5C1, PARK7, UBE2G1, NDUFA1, ATP5H, NDUFB5, NDUFS1, CYC1, COX7B, SDHC, NDUFB3, ATP5O, NDUFA6, PPID, NDUFS4, ATP5G1, COX4I1, SLC25A5, COX6B1, ATP5J, COX7A2, NDUFS2, ATP5G3, COX7A2L, COX6C, UQCRC2, UBE2L3 |
| KEGG OXIDATIVE PHOSPHORYLATION | ATP6V1E1, NDUFS5, ATP5I, ATP5C1, UQCRH, ATP6V1C1, NDUFA1, ATP5H, NDUFB5, NDUFS1, CYC1, COX7B, SDHC, ATP6V1G1, NDUFB3, NDUFA6, ATP5O, NDUFS4, ATP5G1, COX4I1, ATP5J, COX6B1, ATP6V1D, COX7A2, NDUFS2, ATP5G3, COX7A2L, COX6C, UQCRC2, ATP5L |
| BLUM RESPONSE TO SALIRASIB DN | MYCBP, POLA1, TOP2B, BUB1, TMPO, CPS1, CENPA, COCH, RFC5, ABCD3, MCM6, SFRS7, CHEK1, YWHAQ, FZD2, VDAC3, SMC1A, CSE1L, RGS5, NFYB, DHX15, TRIP13, SRP9, ID1, TPX2, PTTG1, PTPN4, CBX1, PRDX3, GPSM2, MID1, KIF2C, HDAC1, ZWINT, GALNT1, STMN1, AURKA, PRPS1, TOPBP1, TOP2A, ENC1, CENPF, CBFB, STIL, PDCD2, MSH2, CDK2AP1, TFDP1, CKS2, IRS1, CDK2, TSPAN7, MEST, LSM5, EBP, BUB1B, H2AFZ, SPAG5, HSP90AA1, MAPRE2, RRM1, NPAT, RFC4, RPA3, B3GNT1, PLS3, CCNB2, TTK, MSH6, CDC25C, DHX9, ANP32A, ATP5G3, RAD51AP1, H2AFV, ACLY, H2AFY, PRIM1 |
| MARTINEZ RESPONSE TO TRABECTEDIN DN | ELOVL6, DKC1, BUB1, TMPO, PPP1CC, PSMB1, AURKA, PSMA4, MTIF2, ADSL, RCOR1, TOP2A, MYCBP2, PTPRK, SRRM2, CDC23, WEE1, CDK7, RNF14, ACSL3, FYN, XBP1, PSMC2, MFAP1, BUB3, PSMC6, JMJD1C, CRLF3, PSMA5, POLD3, GGPS1, HIST1H4C, OGT, MTMR4, LBR, CDC25C, UBE2D2, GTF2H1, XRCC5, HDAC2, DLG5, TARDBP |
| BENPORATH CYCLING GENES | SNUPN, ARL4A, CDC16, POLA1, HMGCR, ILF2, RPS25, BUB1, TMPO, C20ORF111, PRKAR1A, CENPA, SLBP, ZNF207, MYCBP2, NCAPH, CKS1B, PDGFA, MRPS18B, VCL, CDK7, SFRS7, MELK, BUB3, CHEK2, HRSP12, AMD1, RNF113A, OGT, TRIP13, SRF, STAT1, TXNDC9, PTTG1, UNG, MDC1, DCTN6, GPSM2, MID1, KIF2C, DYNLL1, INSIG2, SEPHS1, ZWINT, DKC1, CCNB1, RAD51C, RAN, PWP1, AURKA, TOPBP1, TOP2A, CENPF, MSH2, CKS2, BUB1B, DUSP4, FXR1, TSG101, PPP2CA, RRM1, RFC4, HIST1H4C, CCNB2, ARL6IP1, LBR, MEGF9, RAD51AP1, ANP32B, PRIM1 |
| MUELLER PLURINET | SET, ARL4A, HSPD1, NOLC1, HSP90AB1, SMNDC1, TMPO, CCNB1, AURKA, RFC5, STX3, PSMA6, CKS1B, PPID, EXOSC8, MSH2, LSM3, WEE1, CDK7, CKS2, MBD2, COPS3, CHEK1, PTMA, EXOSC9, LSM5, CHEK2, BUB1B, SNRPE, ANXA3, HPRT1, ATIC, PAK1, RFC4, RPA3, SUMO1, TRIP13, PSIP1, CCNB2, MSH6, SSB, RCHY1, ANP32A, XRCC5, PPM1B, HDAC2 |
| BUYTAERT PHOTODYNAMIC THERAPY STRESS DN | MYCBP, BUB1, AK1, PARP2, STX8, MECP2, VCL, C1ORF156, SFRS7, HRSP12, SYNPO, XPA, UBTF, AMD1, PPIC, MRPL40, WDR7, BLCAP, SRF, M6PR, NHP2L1, ID1, SLC26A2, ALDH5A1, TBL1X, TARDBP, CSTF1, PON2, RABIF, TGFBR2, SEPHS1, SUB1, RAD51C, PPP1R3C, TRIM14, DBF4, PEX11B, AURKA, ZNF238, BAG5, ICMT, LIPA, TOP2A, ENC1, C7ORF44, EBAG9, ATP5G1, ALG8, ZFP161, PIGF, AK2, IRS1, ZNF22, OSTF1, EBP, TEX261, APITD1, HOXA1, ATRN, TCEB3, TIMM8A, B3GNT1, PTDSS1, TGFBI, C5ORF13, PMS1, ANP32A, ATXN10, UROS, EHMT2, PRIM1 |
| KAAB FAILED HEART ATRIUM DN | TGFBR2, CDC16, MAD2L1BP, GTF3A, SLC39A14, PPP1CC, PSMB1, RAN, APP, TXN, CTNNA1, EI24, PSMA3, GPR137B, PSMB5, ACP1, IFITM3, PAFAH1B1, UBE2I, CNIH, ZNF22, PODXL, PDCD6, PPM1A, TCEB1, ACVR1B, TMED10, RBP1, AMD1, PIR, SUMO1, CD59, PIGH, SLC9A6, NHP2L1, PGM1, SRI, PRDX1, RPA1, PLP1, PMP22, LAPTM4A |
| REACTOME G1 S TRANSITION | PSMC5, POLA1, PSMA5, PSMA2, CCNB1, DBF4, PSMB1, PSMC1, PSME2, PSMA4, PSMB7, RPA3, PSMB2, PSMA6, CKS1B, PSMB5, CUL1, WEE1, CDK7, TFDP1, CDK2, PSMC6, PRIM1 |
| PUJANA BRCA CENTERED NETWORK | RFC3, PAICS, TMPO, PPP1CC, RAD51C, AURKA, RRM1, POLR2B, NFYB, RFC4, PRPS1, PRPF4, TOP2A, TOPBP1, TBCA, DUT, LBR, MSH2, UNG, TFDP1, MCM6, MRE11A, COPS3, RPA1, XPO1, BUB3, PPP2R5C, BLM, CHEK2 |
| KIM WT1 TARGETS DN | USP33, ARL4A, MAGOH, COPS5, RPS25, BUB1, TMPO, CDKN1B, CENPA, GLT8D1, SERP1, ASNS, PARP2, AASDHPPT, ASCC3, ABCD3, MRPS18B, GAS2L1, PPP2R5C, BUB3, LAMB1, GTF2H5, PPM1A, SNTB2, FZD2, HBP1, UBE2G1, NFYB, HTATIP2, SMC3, GRK5, HBXIP, ID1, SLC26A2, ATF2, PPM1B, GPSM2, KIF2C, POLD4, C6ORF130, ELOVL6, GLRB, RAD51C, DBF4, CDC40, AURKA, ZNF238, CDC2, ASAH1, TOP2A, CENPF, GNAI1, PPWD1, PIGF, CKS2, GRSF1, XBP1, IRS1, LSM5, DPYSL2, BUB1B, FXR1, ITGB1, MTAP, OXA1L, VAMP4, OIP5, ACTR2, TCF7L2, SLC38A6, CPOX, ARL6IP1, APPBP2, PMS1, ARMCX6 /// LOC653354, RAD51AP1, H2AFV, WDR67, CRKL |
| REACTOME CELL CYCLE CHECKPOINTS | PSMC5, CDC16, PSMA2, DBF4, CCNB1, HUS1, PSMB1, PSME2, PSMA4, RFC5, PSMA6, PSMB5, PSMD10, CDC23, WEE1, MCM6, CHEK1, PSMC2, CDK2, BUB3, PSMC6, CHEK2, BUB1B, UBE2D1, PSMA5, PSMD1, PSMC1, PSMB7, RFC4, RPA3, PSMF1, PSMB2, CCNB2, CDC25C |
| SANA RESPONSE TO IFNG DN | HSPD1, ILF2, HSP90AB1, MGST3, H2AFZ, PRSS23, CCT3, TIMM17A, CSE1L, RAN, PRCP, CCT5, NQO1, HMGCL, SMYD2, SSR2, CTNNAL1, OAT, YWHAQ, HDAC2, CCT4, PRDX1, SNRPD2, PON2, KDELR2 |
| OUELLET OVARIAN CANCER INVASIVE VS LMP UP | COPS5, PSMA2, MRPL3, CTNNA1, FH, NDUFS1, UBE2V2, CKS1B, MDH1, CKS2, MELK, MEST, COPB2, PSMC6, SUMO2, ATP5C1, H2AFZ, DPM1, TMED10, CSE1L, RFC4, SUMO1, MAPRE1, SNRPB2, PSMB2, TCEA1, HMGN1, SLC25A5, OAT, CBX1, KDELR2, IARS, HMGN3 |
| KOBAYASHI EGFR SIGNALING 24HR DN | POLA1, NOLC1, BUB1, ZWINT, TMPO, DBF4, CCNB1, CENPA, AURKA, PRPS1, PARP2, RFC5, SLC20A1, TOP2A, GINS1, CKS1B, DCBLD2, EXOSC8, STIL, MSH2, TFDP1, CKS2, MCM6, SFRS7, MELK, CDK2, BLM, BUB1B, DUSP4, PAICS, H2AFZ, SPAG5, CSE1L, RRM1, RFC4, HIST1H4C, TRIP13, MSH6, TPX2, UNG, ETV5, RAD51AP1, GPSM2, EEF1E1, KIF2C, PRIM1 |
| GRADE COLON AND RECTAL CANCER UP | SET, ANXA5, SEPHS1, GTF3A, C20ORF111, PSMA2, COPS8, CCNB1, KARS, PSMB1, RAN, MRPL3, DAP3, HSPE1, PSMA3, RFC5, SAP18, IFITM1, DDX1, GYG2, CCT8, CDK7, CKS2, C19ORF2, PMPCB, TBCE, MELK, SRP72, PDCD6, H2AFZ, DPM1, RRM1, ATIC, PSMB7, LAPTM4B, UBE2N, PTDSS1, TGFBI, SSB, CCT5, DHX9, DRG1, VBP1, MDC1, NONO, FDFT1, GPSM2, PRDX1, TRAF5, CSTF1, EEF1E1, NPM1 |
| BENPORATH PROLIFERATION | ILF2, BUB1, H2AFZ, GART, DBF4, STMN1, CENPA, AURKA, CSE1L, CTSL2, RFC4, NDUFB5, TOP2A, SHFM1, CENPF, CKS1B, CCNB2, LBR, MSH2, PTTG1, SLC25A5, CKS2, RAD51AP1, HDAC2, H2AFV, GPSM2, SNRPG, KDELR2 |
| REACTOME DNA REPLICATION PRE INITIATION | PSMC5, POLA1, PSMA5, PSMA2, DBF4, PSMB1, PSMC1, PSMD1, PSME2, PSMA4, PSMB7, RPA3, PSMB2, PSMA6, PSMB5, PSMD10, PSMC2, CDK2, PSMC6, PRIM1 |
| APPIERTO RESPONSE TO FENRETINIDE DN | ATP5O, SET, MDH1, RSU1, SLC3A1, H2AFZ, PPP1CC, IARS2, PPIH, IFITM3, ASNS, PTMA, BANF1, HIST1H4C |
| PUJANA XPRSS INT NETWORK | POLA1, NCAPD2, ZWINT, TMPO, RAD51C, PPP1CC, STMN1, CENPA, DCP2, POLR2B, TOP2A, TOPBP1, KATNA1, TBCA, KIAA0101, GINS1, EXOSC8, MSH2, MTF2, FRG1, CASP2, TFDP1, COPS3, PPP2R5C, BUB3, CHEK2, SUZ12, PAICS, LARP7, ZNHIT3, BAT1, RRM1, KIAA0922, RFC4, NFYB, HMMR, SMC3, PSIP1, DUT, LBR, HMGN1, CEP57, UNG, DNAJC9, RAD51AP1, MRE11A, H2AFV, RPA1 |
| NCI SCF SKP2 MEDIATED DEGRADATION OF P27 P21 | PSMC5, PSMA5, PSMA2, PSMB1, PSMD1, PSMC1, PSME2, PSMA4, PSMB7, PSMB2, CKS1B, PSMA6, PSMB5, CUL1, PSMD10, SKP1A, PSMC2, CDK2, PSMC6 |
| GARY CD5 TARGETS DN | PSMC5, SEPHS1, CRYZ, NOLC1, MGEA5, ZWINT, CCNB1, RAN, ATP2B1, NUP133, ADSL, BAG5, ZNF207, ASCC3, CENPF, EIF2S1, SAP18, GINS1, AP4S1, PSMB5, DDX1, DDX18, PDIA6, PPWD1, CYB5B, CDK2AP1, YTHDF3, ZBTB24, GRSF1, SERBP1, PSMC2, PSMC6, EIF4E2, ATP6V1C1, TCEB3, AMD1, PSMD1, SERTAD2, OIP5, MTMR4, TXNDC9, SRI, NCBP1, DHX9, DNAJC7, DRG1, ANP32A, GTF2H1, TARDBP, UMPS, EIF5 |
| REACTOME MITOTIC M M G1 PHASES | BUB1B, PSMC5, APITD1, ZWINT, BUB1, PSMA5, PSMA2, PPP1CC, PPP2CA, CENPA, PSMB1, PSME2, PSMC1, PSMA4, PSMB7, NUP133, MAPRE1, SMC3, CENPF, PSMB2, PSMA6, PSMB5, PSMD10, PSMC2, PPP2R5C, BUB3, PSMC6, KIF2C |
| MARKEY RB1 ACUTE LOF DN | SET, POLA1, HSPD1, BUB1, TMPO, CCNB1, STMN1, CENPA, AURKA, ADSL, TOPBP1, RFC5, CKS1B, LSM3, TRIM37, TMEM106C, CKS2, TFDP1, CDK2, H2AFZ, CSE1L, RFC4, SMC3, OGT, TRIP13, PSIP1, CCNB2, DSTN, RAD51AP1, H2AFV, HDAC2, TARDBP, CDH2, PRIM1 |
| REACTOME REGULATION OF APC ACTIVATORS BETWEEN G1 S AND EARLY ANAPHASE | BUB1B, PSMC5, CDC16, UBE2D1, PSMA5, PSMA2, CCNB1, PSMB1, PSMD1, PSMC1, PSME2, PSMA4, PSMB7, PSMB2, PSMA6, PSMB5, CUL1, PSMD10, CDC23, PSMC2, CDK2, BUB3, PSMC6 |
| RAMALHO STEMNESS UP | SEC23A, IARS2, PRPSAP1, MRPL3, ARIH1, RPL22, MDFI, SEC23IP, STAM, DDX1, PDCD2, MSH2, TOM1L1, TGIF2, USP10, TNPO1, XPO1, EIF4G2, KIF2A, HRSP12, ITGB1, PPIC, LAPTM4B, PLS3, YWHAH, YWHAB, TXNDC9, ACAT2, UBE2D2, RASA1, XRCC5, MRPS31, UMPS, LAPTM4A, IARS |
| REACTOME SIGNALING BY WNT | PSMC5, PSMA5, PSMA2, PPP2CA, PSMB1, PSMD1, PSMC1, PSME2, PSMA4, PSMB7, PSMA3, PSMB2, PSMA6, PSMB5, CUL1, PSMD10, PSMC2, PPP2R5C, PSMC6 |
| CAFFAREL RESPONSE TO THC 24HR 5 DN | NDUFB3, KIAA0101, DUT, ATP5J2, SUB1, PCBP2, PPIH, ASNS, POU4F1, NDUFA1, COPB2, EIF5, HIST1H4C, EBP |
| REN BOUND BY E2F | RFC3, H2AFZ, CENPA, RRM1, RFC4, RPA3, TOP2A, DUT, TTK, MSH2, UNG, PTTG1, MCM6, CHEK1, CDK2, CSTF1, UMPS, BUB3 |
| NCI APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | PSMC5, CDC16, UBE2D1, PSMA5, PSMA2, PSMB1, PSMD1, PSMC1, PSME2, PSMA4, PSMB7, PSMB2, PSMA6, PSMB5, PSMD10, CDC23, PSMC2, PSMC6 |
| NCI AUTODEGRADATION OF CDH1 BY CDH1 APC C | PSMC5, CDC16, UBE2D1, PSMA5, PSMA2, PSMB1, PSMD1, PSMC1, PSME2, PSMA4, PSMB7, PSMB2, PSMA6, PSMB5, PSMD10, CDC23, PSMC2, PSMC6 |
| CORUM PA700-20S-PA28 COMPLEX | PSMB2, PSMA6, PSMC5, PSMB5, PSMD10, PSMA5, PSMA2, PSMB1, PSMD1, PSMC1, PSME2, PSMA4, PSMB7, PSMC2, PSMC6 |
| NCI SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 | PSMC5, PSMA5, PSMA2, PSMB1, PSMD1, PSMC1, PSME2, PSMA4, PSMB7, PSMA6, PSMB2, PSMB5, CUL1, PSMD10, SKP1A, PSMC2, PSMC6 |
| NCI REGULATION OF ACTIVATED PAK 2P34 BY PROTEASOME MEDIATED DEGRADATION1 | PSMC5, PSMA5, PSMA2, PAK2, PSMB1, PSMD1, PSMC1, PSME2, PSMA4, PSMB7, PSMA6, PSMB2, PSMB5, PSMD10, PSMC2, PSMC6 |
| NCI APC C CDC20 MEDIATED DEGRADATION OF SECURIN | PSMC5, CDC16, UBE2D1, PSMA5, PSMA2, PSMB1, PSMD1, PSMC1, PSME2, PSMA4, PSMB7, PSMB2, PSMA6, PSMB5, PSMD10, CDC23, PTTG1, PSMC2, PSMC6 |
| REACTOME CDC20 PHOSPHO APC MEDIATED DEGRADATION OF CYCLIN A | BUB1B, PSMC5, CDC16, UBE2D1, PSMA5, PSMA2, PSMB1, PSMD1, PSMC1, PSME2, PSMA4, PSMB7, PSMB2, PSMA6, PSMB5, PSMD10, CDC23, PSMC2, BUB3, PSMC6 |
| LEE LIVER CANCER SURVIVAL DN | ANXA3, SET, CLIC1, ATP5C1, UBE2D1, CCNB1, RAN, SLBP, RPE, ACTR3, MAPRE1, HIST1H4C, TOPBP1, CENPF, SNRPB2, CALM2, NSF, YWHAB, MSH6, HMGN1, VCL, CCT5, CKS2, YWHAQ, HDAC2, PTMA, SNRPG, ANXA4, BUB3, EEF1E1, LAMB1 |
| HU ANGIOGENESIS DN | SET, SOD1, PFN2, H2AFZ, PSMB1, RPA3, DHX15, GNAI1, ATP6V1G1, ATP5O, MDH1, GMPS, HMGN1, CDK2AP1, GTF2A2, SMYD2, CKS2, DARS |
| NCI CDC20 PHOSPHO APC C MEDIATED DEGRADATION OF CYCLIN A | BUB1B, PSMC5, CDC16, UBE2D1, PSMA5, PSMA2, PSMB1, PSMD1, PSMC1, PSME2, PSMA4, PSMB7, PSMB2, PSMA6, PSMB5, PSMD10, CDC23, PSMC2, BUB3, PSMC6 |
| REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC | PSMC5, CDC16, UBE2D1, PSMA5, PSMA2, PSMB1, PSMD1, PSMC1, PSME2, PSMA4, PSMB7, PSMB2, PSMA6, PSMB5, PSMD10, CDC23, PSMC2, PSMC6 |
| MOREAUX MULTIPLE MYELOMA BY TACI DN | NNT, DKC1, DBF4, GLT8D1, RAN, DHX29, CDC2, PSMA3, AASDHPPT, ORC5L, DDX1, DDX18, CDC23, TERF1, EBNA1BP2, SSBP1, TMEM135, SPAST, CHEK1, ERCC1, BUB3, PPP2R5C, LSM5, PDCD6, TTRAP, PPP1R12A, BARD1, FEM1B, SHFM1, SNX19, CCT2, CEP57, CCT5, SF3B2, IK, DARS, IARS, ATP5L |
| TIEN INTESTINE PROBIOTICS 6HR DN | RDBP, TMPO, RIN2, CENPA, RBM34, ADSL, STX3, NDUFA6, DDX1, GYG2, TRIM37, MTRR, ATP6V1D, TAF9, SPAST, MELK, SUCLA2, RBM9, UBE2D1, FXR1, TSG101, BAMBI, TAX1BP3, PSMC1, ACAA2, TTC1, FHL2, ANXA6, RCHY1, SMYD2, ARMCX6 /// LOC653354, PPM1B |
| PAL PRMT5 TARGETS UP | SET, NNT, PPP1R7, CETN2, TMPO, STMN1, SLBP, NCBP2, ANAPC5, TOPBP1, RFC5, IGBP1, CKS1B, PSMB5, PTPRK, LSM3, NFYC, ST7, CKS2, SFRS7, NUP88, COPS3, ARL2BP, TMEM5, LARP7, RRM1, TRIP13, PSIP1, CCNB2, FMR1, TTK, YWHAB, TGFBI, CDC25C, RASA1, SPCS2, NONO, HAT1, H2AFV, CFDP1, TARDBP, EHMT2, PRIM1, ERH |
| GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING DN | BUB1B, ZWINT, BUB1, VDAC3, CSE1L, RRM1, RFC4, LEPR, OIP5, TOP2A, TRIP13, GINS1, CKS1B, CCNB2, MSH2, MCM6, RAD51AP1, ATP5G3, CHEK1, MELK, NPM3, APOBEC3B, KIF2C |
| SOTIRIOU BREAST CANCER GRADE 1 VS 3 UP | ZWINT, BUB1, TMPO, CCNB1, STMN1, CENPA, AURKA, TXN, TOP2A, CENPF, NCAPH, GINS1, STIL, CKS2, MCM6, CHEK1, MELK, SNRPG, CDK2, BLM, BUB1B, TCEB1, H2AFZ, SPAG5, RFC4, OIP5, TRIP13, TTK, CCNB2, TPX2, PTTG1, CCT5, H2AFV, APOBEC3B, KIF2C |
| CORUM PA28GAMMA-20S PROTEASOME | PSMA6, PSMB2, PSMB5, PSMA2, PSMA5, PSMB6, PSMB1, PSMA4, PSMB7, PSMA3 |
| KANG DOXORUBICIN RESISTANCE UP | BUB1B, CDKN3, BUB1, ZWINT, CENPA, BARD1, AURKA, RRM1, RFC4, OIP5, HMMR, TOP2A, GINS1, KIAA0101, TPX2, CDC6, NQO1, RAD51AP1, BIRC5 |
| BIOCARTA PROTEASOME PATHWAY | PSMA6, PSMB2, PSMB5, PSMA2, PSMA5, RPN2, PSMB1, PSMA4, PSMB7, PSMA3 |
| LINDGREN BLADDER CANCER CLUSTER 3 UP | DYNLT3, HSPD1, BUB1, ZWINT, TMPO, PRPS2, RAD51C, DBF4, CCNB1, STMN1, CENPA, AURKA, SERP1, YARS, TOP2A, CENPF, CKS1B, MSH2, TOM1L1, TMEM106C, HIST1H3H, CKS2, ZNF148, YWHAQ, AK2, MELK, CDK2, ANXA4, COPB2, EBP, H2AFZ, ATP6V1C1, GNPAT, RFC4, RPA3, MAPRE1, TRIP13, CCNB2, INSIG1, PTTG1, MDC1, H2AFV, PRDX1, KIF2C |
| MISSIAGLIA REGULATED BY METHYLATION DN | BUB1B, PAICS, TMPO, ZWINT, H2AFZ, STMN1, CSE1L, PIR, RRM1, RFC4, RPA3, RFC5, CENPF, PSIP1, MSH6, LBR, ACAT2, MDC1, PCBP2, CHEK1, ANP32B, PRIM1, EBP |
| ALONSO METASTASIS UP | SET, PFKM, PRKAR1A, PPP1R3C, RAN, ADSL, LIPA, CYC1, ENC1, GNG12, CKS1B, MDH1, CBFB, WEE1, COX6B1, YWHAQ, NCOA4, MFAP1, PPP2R5C, NPC2, ASH2L, TCEB1, MAPRE1, HIST1H4C, HBXIP, SRI, CCT5, UBE2D2, BTF3, VBP1, XRCC5, CDYL, EIF5, LAPTM4A |
| CORUM PA28-20S PROTEASOME | PSMA6, PSMB2, PSMB5, PSMA2, PSMA5, PSMB6, PSMB1, PSMA4, PSME2, PSMB7, PSMA3 |
| SAKAI TUMOR INFILTRATING MONOCYTES DN | COPS5, PRKAR1A, RAD51C, SUB1, RAN, PPIC, TXN, ARIH1, TOP2A, SNRPB2, PSMB5, CCT8, CDK7, TAF9, PRDX3, NCOA4 |
| CORUM 20S PROTEASOME | PSMA6, PSMB2, PSMB5, PSMA2, PSMA5, PSMB6, PSMB1, PSMA4, PSMB7, PSMA3 |
| CORUM 26S PROTEASOME | PSMB2, PSMA6, PSMC5, PSMB5, PSMA2, PSMA5, PSMB1, PSMC1, PSMA4, PSMB7, PSMC2, PSMA3, PSMC6 |
| MOREAUX B LYMPHOCYTE MATURATION BY TACI DN | TTRAP, PPP1R12A, DKC1, BARD1, RAN, CDC2, AASDHPPT, DDX1, CCT2, CDC23, EBNA1BP2, CCT5, SSBP1, CHEK1, IK, IARS, LSM5 |
| ROSTY CERVICAL CANCER PROLIFERATION CLUSTER | ZWINT, BUB1, TMPO, DBF4, CCNB1, CENPA, AURKA, CDC2, TOP2A, CENPF, NCAPH, GINS1, STIL, CKS2, CHEK1, MELK, EBP, BUB1B, H2AFZ, SPAG5, RPA3, OIP5, TRIP13, TTK, CCNB2, TPX2, PTTG1, C18ORF10, RAD51AP1, APOBEC3B, SMC4, KIF2C |
| BHATTACHARYA EMBRYONIC STEM CELL | SET, SEPHS1, RPL24, ELOVL6, PSMA2, CCNB1, CALU, PSMA3, IFITM1, PSIP1, CCT8, TPX2, SSB, PTTG1, IDH1, SFRS7, DSG2, HDAC2, CCNC, PODXL, NPM1 |
| CROONQUIST NRAS SIGNALING DN | BUB1B, ZWINT, POLD3, CCNB1, RAD51C, SPAG5, CENPA, CSE1L, AURKA, OIP5, TOP2A, GNAI1, TRIP13, NCAPH, GINS1, CCNB2, STIL, TPX2, CDC25C, WEE1, CHEK1, EIF5, KIF2C, CHEK2 |
| CROONQUIST IL6 DEPRIVATION DN | BUB1B, GINS1, NCAPH, CCNB2, BUB1, ZWINT, WEE1, CCNB1, CENPA, CKS2, AURKA, CHEK1, OIP5, TOP2A, KIF2C, TRIP13 |
| RHODES CANCER META SIGNATURE | SNRPE, HSPD1, ILF2, MRPL3, PSME2, RFC4, HSPE1, TOP2A, OGT, SDHC, CCT5, SSBP1, CKS2, NONO, CCT4, PTMA, SSR1, PPP2R5C, COPB2, IARS, KDELR2 |
| CHANG CYCLING GENES | CCNB2, ARL4A, ILF2, DKC1, CENPA, AURKA, CKS2, MELK, TOP2A |
| GRAHAM CML DIVIDING VS NORMAL QUIESCENT UP | |
| DANG BOUND BY MYC | |
| ROME INSULIN TARGETS IN MUSCLE UP | |
| BOYAULT LIVER CANCER SUBCLASS G123 UP | GINS1, SNRPE, CCNB2, TMPO, CCT3, SGCE, HAT1, CBX1, ACLY, RFC4, SMC4, PON2 |
| PUJANA BRCA2 PCC NETWORK | |
| NCI AURORA B PATHWAY | |
| NCI PLK1 PATHWAY | |
| CORUM C COMPLEX SPLICEOSOME | |
| REACTOME PEROXISOMAL LIPID METABOLISM | |
| CORUM F1F0-ATP SYNTHASE EC 3.6.3.14 MITOCHONDRIAL | |
| NCI HOST INTERACTIONS OF HIV FACTORS | |
| CHOI ATL CHRONIC VS ACUTE DN | |
| NCI REPAIR SYNTHESIS FOR GAP FILLING BY DNA POLYMERASE IN TC NER | |
| FRASOR RESPONSE TO SERM OR FULVESTRANT DN | |
| CORUM 6S METHYLTRANSFERASE AND RG-CONTAINING SM PROTEINS COMPLEX | |
| RODRIGUES THYROID CARCINOMA ANAPLASTIC UP | |
| NCI ORC1 REMOVAL FROM CHROMATIN | |
| REACTOME TRNA AMINOACYLATION | |
| SESTO RESPONSE TO UV C5 | |
| ZHAN VARIABLE EARLY DIFFERENTIATION GENES DN | |
| REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 | |
| CORUM DNA-PK-KU-EIF2-NF90-NF45 COMPLEX | |
| REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 | |
| REACTOME CHOLESTEROL BIOSYNTHESIS | |
| BOYAULT LIVER CANCER SUBCLASS G23 UP | |
| JISON SICKLE CELL DISEASE DN | |
| CORUM DNA SYNTHESOME COMPLEX 13 SUBUNITS | |
| REACTOME HOST INTERACTIONS OF HIV FACTORS | |
| TIEN INTESTINE PROBIOTICS 2HR DN | |
| REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX | |
| REACTOME SYNTHESIS OF DNA | |
| CORUM EXOSOME | |
| MEINHOLD OVARIAN CANCER LOW GRADE DN | |
| REACTOME CITRIC ACID CYCLE | |
| REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | |
| ROZANOV MMP14 CORRELATED | |
| NCI VPU MEDIATED DEGRADATION OF CD4 | |
| KEGG STEROID BIOSYNTHESIS | |
| REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | |
| CORUM 17S U2 SNRNP | |
| GENTILE RESPONSE CLUSTER D3 | |
| NCI CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 | |
| SEIDEN ONCOGENESIS BY MET | |
| MORI IMMATURE B LYMPHOCYTE DN | |
| CORUM 18S U11/U12 SNRNP | |
| SAKAI CHRONIC HEPATITIS VS LIVER CANCER UP | |
| WAKASUGI HAVE ZNF143 BINDING SITES | |
| CAFFAREL RESPONSE TO THC 24HR 5 UP | |
| CHANDRAN METASTASIS TOP50 UP | |
| REACTOME MITOTIC PROMETAPHASE | |
| KEGG PROTEIN EXPORT | |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | |
| REACTOME P53 INDEPENDENT DNA DAMAGE RESPONSE | |
| WANG LMO4 TARGETS UP | |
| NCI CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX | |
| HOSHIDA LIVER CANCER SUBCLASS S2 | |
| BYSTRYKH HEMATOPOIESIS STEM CELL AND BRAIN QTL CIS | |
| FINETTI BREAST CANCER BASAL VS LUMINAL | |
| NCI INSULIN SYNTHESIS AND SECRETION | |
| REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | |
| GOLDRATH HOMEOSTATIC PROLIFERATION | |
| NCI MRNA SPLICING MAJOR PATHWAY | |
| ZHONG RESPONSE TO AZACITIDINE AND TSA DN | |
| FOURNIER ACINAR DEVELOPMENT LATE 2 | |
| MOHANKUMAR TLX1 TARGETS UP | |
| MORI LARGE PRE BII LYMPHOCYTE UP | |
| TAKAO RESPONSE TO UVB RADIATION DN | |
| CORUM SPLICEOSOME | |
| JI RESPONSE TO FSH DN | |
| KEGG PROTEASOME | |
| NCI VIF MEDIATED DEGRADATION OF APOBEC3G | |
| WENDT COHESIN TARGETS UP | |
| NCI DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX | |
| SCHLOSSER MYC TARGETS AND SERUM RESPONSE DN | |
| SONG TARGETS OF IE86 CMV PROTEIN | |
| FUJII YBX1 TARGETS DN | |
| NCI CITRIC ACID CYCLE TCA CYCLE | |
| JAERVINEN AMPLIFIED IN LARYNGEAL CANCER | |
| SEIDEN MET SIGNALING | |
| JIANG HYPOXIA CANCER | ARPC5, EDN2, PGM1, PPT1, RPN2, SERP1, SUMO1, RPL22, HAX1, CENPF, ATP6V1A |
| MMS MOUSE LYMPH HIGH 4HRS UP | |
| RHODES UNDIFFERENTIATED CANCER | |
| ZHAN MULTIPLE MYELOMA SUBGROUPS | |
| BASSO B LYMPHOCYTE NETWORK | |
| ODONNELL TARGETS OF MYC AND TFRC DN | |
| NCI CYTOSOLIC TRNA AMINOACYLATION | |
| NCI ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | |
| MOLENAAR TARGETS OF CCND1 AND CDK4 DN | |
| ZHAN MULTIPLE MYELOMA PR UP | |
| NCI PHOSPHORYLASE KINASE ACTIVATES GLYCOGEN PHOSPHORYLASE | |
| NCI APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS | |
| ONKEN UVEAL MELANOMA UP | |
| HOFFMANN LARGE TO SMALL PRE BII LYMPHOCYTE UP | |
| NCI PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | |
| NCI MITOTIC PROMETAPHASE | |
| GOLUB ALL VS AML UP | |
| REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | |
| LAIHO COLORECTAL CANCER SERRATED UP | |
| KEGG AMINOACYL TRNA BIOSYNTHESIS | |
| REACTOME CYCLIN A1 ASSOCIATED EVENTS DURING G2 M TRANSITION | |
| SCIBETTA KDM5B TARGETS DN | |
| KAUFFMANN DNA REPAIR GENES | |
| REACTOME TRANSFORMATION OF LANOSTEROL TO CHOLESTEROL | |
| REACTOME G2 M CHECKPOINTS | |
| GOLDRATH ANTIGEN RESPONSE | |
| ONKEN UVEAL MELANOMA DN | |
| NCI TRANSFORMATION OF LANOSTEROL TO CHOLESTEROL | |
| NAKAMURA TUMOR ZONE PERIPHERAL VS CENTRAL UP | |
| CHEMNITZ RESPONSE TO PROSTAGLANDIN E2 UP | |
| FERRANDO T ALL WITH MLL ENL FUSION DN | |
| REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G | |
| DING LUNG CANCER EXPRESSION BY COPY NUMBER | |
| NCI FOLDING OF ACTIN BY CCT TRIC | |
| STEIN ESRRA TARGETS DN | |
| KAYO AGING MUSCLE DN | |
| NCI APC CDC20 MEDIATED DEGRADATION OF NEK2A | |
| KEGG PROPANOATE METABOLISM | |
| LEE METASTASIS AND RNA PROCESSING UP | |
| RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY UP | |
| RICKMAN METASTASIS UP | |
| YU MYC TARGETS UP | |
| CHIANG LIVER CANCER SUBCLASS PROLIFERATION UP | |
| REACTOME S PHASE | |
| FINETTI BREAST CANCER KINOME RED | |
| CHOI ATL STAGE PREDICTOR | |
| FARMER BREAST CANCER CLUSTER 2 | |
| OUELLET CULTURED OVARIAN CANCER INVASIVE VS LMP UP | |
| VANTVEER BREAST CANCER METASTASIS DN | |
| NCI FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | |
| NCI REGULATION OF ACTIVATED PAK 2P34 BY PROTEASOME MEDIATED DEGRADATION | |
| FLECHNER PBL KIDNEY TRANSPLANT OK VS DONOR UP | |
| NCI UBIQUITIN MEDIATED DEGRADATION OF PHOSPHORYLATED CDC25A | |
| AMUNDSON GAMMA RADIATION RESPONSE | |
| REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION | |