| Gene Set | Leading Edge Genes |
|---|---|
| WONG EMBRYONIC STEM CELL CORE | NCAPH, CCNB2, NDUFA9, SSB, HADH, CSE1L, RRM1, ADSL, SMC4, TOP2A, ADH5, IARS |
| CAIRO HEPATOBLASTOMA CLASSES UP | LRPPRC, TMEM97, TMPO, CCNB1, CCT6A, CENPA, CSE1L, RRM1, SF3B3, ADSL, TOP2A, CCNB2, PTDSS1, DDX1, TTK, MSH6, SSB, SSRP1, ACLY, SMC4, IARS |
| PUJANA BRCA2 PCC NETWORK | ATR, CASP6, TMPO, FANCG, RRM1, TOP2A, TOPBP1, NCAPH, PSIP1, PTDSS1, EXOSC8, HMGN1, ACAT2, CDC23, CASP2, SSRP1, SMC4, PPP2R5C |
| MANALO HYPOXIA DN | CSE1L, RRM1, MRPL40, EXOSC8, ACAT2, FANCG, IARS |
| PUJANA XPRSS INT NETWORK | PSIP1, RFC3, EXOSC8, HMGN1, TMPO, DNAJC9, CASP2, RRM1, SMC4, TOPBP1, TOP2A, PPP2R5C |
| PUJANA BRCA CENTERED NETWORK | RFC3, RRM1, TMPO, PPP2R5C, TOP2A, TOPBP1 |
| REACTOME MITOTIC M M G1 PHASES | SMC3, PPP2R5C, CENPA, PSMB1 |
| REACTOME CELL CYCLE MITOTIC | CETN2, CDC23, SMC3, PPP2R5C, CENPA |
| REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | RFC3, ATR |
| YU MYC TARGETS UP | |
| REACTOME CELL CYCLE CHECKPOINTS | |
| BOYAULT LIVER CANCER SUBCLASS G23 UP | |
| KEGG MISMATCH REPAIR | |
| HORIUCHI WTAP TARGETS DN | |
| ZHONG RESPONSE TO AZACITIDINE AND TSA DN | |
| MORI LARGE PRE BII LYMPHOCYTE UP | |
| NUYTTEN EZH2 TARGETS DN | TMEM97, CASP6, TMPO, CETN3, FANCG, CCNB1, CENPA, DDHD2, CSE1L, NUP155, TOP2A, TOPBP1, NCAPH, SP3, TTK, EXOSC8, EIF4EBP2, PAPOLA, PPP3CB, BRD8, NUP88, SSRP1, SMC4, NEK9 |
| MARKEY RB1 ACUTE LOF DN | |
| KAUFFMANN DNA REPAIR GENES | |
| ZHANG RESPONSE TO IKK INHIBITOR AND TNF DN |
| Color legend | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| q-value | -1 | -0.2 | -0.05 | -0.01 | -0.001 | -0.0001 | |||||
| Color | |||||||||||
| yersinia enterocolitica wap bl6 | pseudomonas aeruginosa fdr440 | pseudomonas aeruginosa | streptococcus pneumoniae d39 | GeneSet Name |
|---|---|---|---|---|
| -0.00014 | -0.11079 | -0.00224 | -0.09472 | WONG_EMBRYONIC_STEM_CELL_CORE |
| -0.00045 | -0.05619 | -0.00726 | -0.10890 | CAIRO_HEPATOBLASTOMA_CLASSES_UP |
| -0.04536 | -0.00002 | -0.00097 | -0.01261 | PUJANA_BRCA2_PCC_NETWORK |
| -0.03448 | -0.14929 | -0.03027 | -0.02142 | MANALO_HYPOXIA_DN |
| -0.03541 | -0.00019 | -0.00097 | -0.00417 | PUJANA_XPRSS_INT_NETWORK |
| -0.06827 | -0.00050 | -0.01365 | -0.01894 | PUJANA_BRCA_CENTERED_NETWORK |
| -0.09142 | -0.16003 | -0.00227 | -0.03998 | REACTOME_MITOTIC_M_M_G1_PHASES |
| -0.02742 | -0.00616 | -0.00096 | -0.03832 | REACTOME_CELL_CYCLE_MITOTIC |
| -0.08733 | -0.00025 | -0.06489 | -0.06131 | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS |
| -0.12252 | -0.04480 | -0.12022 | -0.02289 | YU_MYC_TARGETS_UP |
| -0.01735 | -0.08869 | -0.00423 | -0.18352 | REACTOME_CELL_CYCLE_CHECKPOINTS |
| -0.13323 | -0.15757 | -0.17995 | -0.12725 | BOYAULT_LIVER_CANCER_SUBCLASS_G23_UP |
| -0.10213 | -0.00771 | -0.13621 | -0.16509 | KEGG_MISMATCH_REPAIR |
| -0.13330 | -0.05527 | -0.00235 | -0.01609 | HORIUCHI_WTAP_TARGETS_DN |
| -0.01800 | -0.07111 | -0.10608 | -0.16660 | ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_DN |
| -0.06022 | -0.00134 | -0.02813 | -0.00446 | MORI_LARGE_PRE_BII_LYMPHOCYTE_UP |
| -0.01992 | -0.00193 | -0.00115 | -0.01919 | NUYTTEN_EZH2_TARGETS_DN |
| -0.08737 | -0.07746 | -0.08917 | -0.06105 | MARKEY_RB1_ACUTE_LOF_DN |
| -0.10612 | -0.00283 | -0.04560 | -0.01600 | KAUFFMANN_DNA_REPAIR_GENES |
| -0.14746 | -0.01852 | -0.04466 | -0.00279 | ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_DN |