| Gene Set | Leading Edge Genes |
|---|
| WONG MITOCHONDRIA GENE MODULE | GSTO1, MRPS18A, NDUFA3, ATP5G2, NDUFB8, ATOX1, MRPL49, NDUFA1, MRPS30, NDUFS8, CYC1, TIMM13, ATP5O, NDUFS6, TUFM, ECHS1, CPT1A, NDUFS2, NDUFAB1, NDUFB2, NDUFS3, PTRH2, SUCLA2, MRPL13, SURF1, NFS1, NDUFC1, DLD, ABCB6, SDHB, MRPS16, TIMM17B, COX5B, TFAM, NDUFA10, NDUFAF1, ACAT1, UQCRQ, SUCLG1, NDUFB6, SEC61G, COX8A, COX7C |
| REACTOME GLUCOSE REGULATION OF INSULIN SECRETION | NDUFA13, DLD, SDHB, NDUFS7, NDUFA3, ATP5D, NDUFB8, SDHA, IDH3G, NDUFA1, COX5B, NDUFA10, NDUFS8, CYC1, UQCRC1, ATP5O, ETFB, NDUFS6, UQCRQ, SUCLG1, NDUFS2, NDUFB6, NDUFAB1, COX7C, NDUFS3, SUCLA2, NDUFC1 |
| MOOTHA HUMAN MITODB 6 2002 | MRPL9, UQCR, NDUFA3, MRPS18A, NDUFB8, SDHA, HADHB, CPT2, NDUFA1, CYC1, TIMM13, ATP5O, UQCRC1, ALDH4A1, MBD3, CYB5B, ECHS1, TUFM, ABCB7, SSBP1, NDUFAB1, MRPL16, NDUFB2, SUCLA2, NDUFS3, MRPL46, MRPL13, MRPL22, ABCB6, DLD, NDUFS7, MRPS7, ATP5D, MRPS16, MRPS12, MRPL35, MRPS11, MRPL4, TIMM44, MTCH2, TIMM17B, ACP6, ACAA2, HPS1, ETFB, MRPS2, ACAT1, CPOX, ACAD8, HADHA, HADH, UROS, MRPL48 |
| KEGG PARKINSONS DISEASE | SDHB, NDUFS7, NDUFA3, ATP5D, ATP5G2, NDUFB8, PARK7, CASP3, SDHA, NDUFA1, COX5B, NDUFA10, NDUFS8, CYC1, ATP5O, UQCRC1, NDUFS6, UBE2J1, UQCRQ, NDUFS2, NDUFB6, NDUFAB1, COX7C, NDUFS3, NDUFC1 |
| KEGG ALZHEIMERS DISEASE | NDUFS7, SDHB, NDUFA3, ATP5D, ATP5G2, NDUFB8, CASP3, SDHA, PLCB3, NDUFA1, NDUFA10, NDUFS8, CYC1, UQCRC1, ATP5O, NDUFS6, APH1A, UQCRQ, NDUFB6, NDUFAB1, COX7C, NDUFS3, NDUFC1 |
| KEGG HUNTINGTONS DISEASE | SDHB, NDUFS7, NDUFA3, ATP5D, ATP5G2, NDUFB8, CASP3, SDHA, PLCB3, NDUFA1, TFAM, NDUFA10, NDUFS8, CYC1, POLR2J, UQCRC1, ATP5O, NDUFS6, POLR2D, UQCRQ, NDUFB6, NDUFAB1, COX7C, NDUFS3, DCTN1, NDUFC1 |
| MOOTHA MITOCHONDRIA | MRPL9, UQCR, NDUFA3, MRPS18A, C1QBP, NDUFB8, SDHA, HADHB, NDUFA1, CYC1, TIMM13, ATP5O, UQCRC1, NDUFS6, ALDH4A1, MBD3, CYB5B, ECHS1, TUFM, ATPAF2, SSBP1, ABCB7, NDUFAB1, MRPL16, NDUFB2, NDUFS3, MRPL13, MRPL22, DLD, MRPS7, ATP5D, MRPS16, MRPS12, MRPL35, MRPS11, TIMM44, MTCH2, ACP6, ACAA2, ETFB, MRPS2, ACAT1, CPOX, ACAD8, HADHA, HADH, COX7C, MRPL48 |
| KEGG OXIDATIVE PHOSPHORYLATION | ATP5C1, NDUFS7, SDHB, NDUFA3, ATP5G2, NDUFB8, SDHA, NDUFA1, NDUFA10, NDUFS8, CYC1, UQCRC1, ATP5O, NDUFS6, ATP5G1, UQCRQ, NDUFB6, NDUFAB1, COX7C, NDUFB2, NDUFS3, NDUFC1 |
| TIEN INTESTINE PROBIOTICS 24HR UP | KIF20A, MRPL9, FAIM, C1QBP, PEPD, DBF4, ALAD, ADSL, HSPE1, FBXO3, RDH11, TOPBP1, HSPA14, TIMM13, ERCC3, EMG1, LSS, CYB5B, ECHS1, ENTPD4, TIPIN, FBXO9, LRPAP1, NDUFB2, SUCLA2, EBP, NDUFC1, MRPL22, NDUFA13, MMD, POLR2L, HSBP1, SNRPD3, GGA2, NEDD8, PHB, ACAA2, PDCD5, CUL2, MRPS2, ACAT2, SFRS2, TSN, FKBP3, H2AFV, IDI1, HMGCS1, STARD7, DHCR7 |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 17 | SDHB, COPS6, MRPS7, COPE, MRPS12, MRPS11, ADSL, ALDH9A1, UFC1, TIMM13, RNF7, ERCC3, PIAS3, LRPAP1, NDUFAB1, DDT, MRPL34, MRPL16, LIAS, CSNK2B, HMGCS1, NDUFS3, HSD17B4, HMBS, STARD7 |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | CPSF3L, RBBP4, SDHB, HECTD3, MRPS16, USP48, PPCS, CTNNB1, NADK, ELOVL1, ZMYM4, PEF1, ACAT1, ACAD8, ECHS1, LETM1, UTP11L, CWF19L1, PQLC2, QARS, MRPL48, HMBS, MED8 |
| DAIRKEE TERT TARGETS UP | PIN1, PRPF31, SSNA1, NDUFA13, RDBP, MRPS18A, ATP5D, ATP5G2, NGRN, IDH3G, STOML2, NEDD8, MECR, SGTA, UQCRC1, MRPS2, NMT1, CCS, ECHS1, CDC34, LMAN2, COPS4, QARS, NIF3L1, MRPL48, BET1 |
| RICKMAN METASTASIS UP | NMT1, CETN2, UPF3B, IDH1, ABCB7, ITGB5, MRPS35, E2F6 |
| PELLICCIOTTA HDAC IN ANTIGEN PRESENTATION UP | ERGIC3, PSMD2, PSMD6, PSMA5, COPE, PDIA4, YIPF5, PSMB3, TRAPPC4, COPZ1, BCAP31, SIL1 |
| CORUM CSA COMPLEX | |
| KEGG STEROID BIOSYNTHESIS | |
| REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | |
| MORI PLASMA CELL UP | |
| ZHANG RESPONSE TO CANTHARIDIN DN | |
| REACTOME DNA REPAIR | POLD2, ERCC3, POLR2E, POLR2D, TDP1, XPC, RAD50, POLR2B, ERCC2, MNAT1, POLR2J |
| REACTOME INTEGRATION OF ENERGY METABOLISM | |
| CORUM CSA-POLIIA COMPLEX | |
| CORUM 39S RIBOSOMAL SUBUNIT MITOCHONDRIAL | MRPL22, MRPL34, MRPL16, MRPL35 |
| MOOTHA FFA OXYDATION | |
| BYSTRYKH HEMATOPOIESIS STEM CELL AND BRAIN QTL CIS | |
| KEGG NUCLEOTIDE EXCISION REPAIR | ERCC3, XPC, POLE3, CETN2, ERCC2, CUL4B, MNAT1 |