| Gene Set | Leading Edge Genes |
|---|
| SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN UP | ATP5I, GIPC1, NDUFB8, POLR2I, CSNK1G2, GALE, ICMT, NSDHL, TBCA, UQCRC1, AES, PSMB5, RXRA, DCXR, CDK2AP2, STK3, DPAGT1, MBD3, ATP5J2, DHCR24, PPIB, DDT, ARHGAP1, COX6C, HMBS, EBP, NDUFV2, SCAND1, MAP2K2, GLUD1, HEXIM1, PSMD13, ETV5, MORF4L2, HMGCS1, PSMB3, HSD17B4, DHCR7 |
| ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE UP | SET, FLOT1, MGST3, CHPT1, METRN, DYNLRB1, SH3D19, CASK, SDF2L1, ICT1, NDUFA8, RNASEH2A, TK1, XRCC6BP1, CNN3, NANS, COPB2, SRXN1, TSPAN14, ARL2BP, PAPSS1, LMNA, MRPL40, GMNN, CCT2, PSMD6, IDH1, PHPT1, IDI1, HIST2H2BE, TFG, SEC61B, ELOVL6, COPE, ZMAT3, AP1S1, NCBP2, GALNTL4, APEX1, PDIA6, TOM1L1, CDK2AP2, SLC25A4, TMED7, ALG14, HEY1, CDR2, STT3B, SURF1, VAMP5, PIR, MAP2K2, YIPF1, CKAP4, MAPRE1, CCNA2, PPP1CA, TXNRD1, DNAJB11, SLC9A6, NDUFB3, PSMD2, MSH6, TUBB2C, DARS2 |
| STEIN ESRRA TARGETS | ASPH, MGST3, TEX2, CSNK1G2, ST3GAL5, C16ORF61, UQCRFS1, USP4, NDUFA8, ATP5O, MDH1, CAV2, SLC25A4, GSTM1, GAS2L1, UGP2, GMCL1, TUBB6, NANS, ALAS1, EBP, SLC25A3, ATP5C1, FZD2, DLAT, MOSC2, ATP6V0E2, GATAD1, PHB, NQO2, FBXL15, MSH6, HEXIM1, SUCLG1, RAB35, CS, ENDOG, RABIF |
| KEGG ALZHEIMERS DISEASE | BAD, NDUFV2, BACE1, ATP5C1, NDUFB8, UQCRH, MAPK3, ADAM10, UQCRFS1, NDUFA8, CALM2, NDUFB3, ATP5O, ATP5A1, NDUFA4, IDE, COX7C, COX6C, NDUFB10, NDUFC1 |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 13 | 2010107E04RIK, UQCR, RBM14, NDUFB8, ANXA2, GPX4, MRPS33, DYNLRB1, DAP3, CSRP2, NCBP2, PIGX, 2810428I15RIK, COMMD1, USMG5, S100A6, ATP5O, HDDC2, CYB5B, SLC35B2, GUK1, 1810046J19RIK, PPIB, UQCRC2, PPP2R5C, EBP, TIMM8B, NDUFC1, 2410015M20RIK, TCEB2, PARK7, LGALS1, GSTM5, TSEN34, MRPL18, LSMD1, NDUFA9, PCCB, ELOF1, CHMP2A, 1810063B05RIK, ECH1, CCDC56, 0610007P14RIK |
| BLUM RESPONSE TO SALIRASIB DN | MYCBP, ESPL1, TMPO, PLK1, CENPA, MCCC2, GAMT, ATP5J2, DHCR24, RNASEH2A, TK1, CNN3, SLC25A10, EBP, CKB, BUB1B, ISYNA1, FZD2, LMNA, MAPRE2, CCNA2, CYB5A, PLS3, NDUFB3, TTK, TUBG1, GMNN, CCNB2, MSH6, SRP9, POLE2, TUBB2C, PRDX3, GPSM2, CRIP2, FASN, SDC1 |
| LINDGREN BLADDER CANCER CLUSTER 3 UP | CCNE1, DYNLT3, TMPO, PLK1, PRDX4, TESK2, CCNB1, CENPA, ASS1, ALDH9A1, NQO2, MAPRE1, TXNRD1, CCNB2, GMNN, INSIG1, TOM1L1, PGM3, SUCLG1, GLO1, GMCL1, RNASEH2A, TK1, IDH2, ANXA4, COPB2, ALAS1, EBP, BIRC5, TFG |
| RHEIN ALL GLUCOCORTICOID THERAPY DN | SET, EMP1, MLF1IP, PRDX4, MRPS33, BZW2, ADSL, TBCA, NDUFA8, MDH1, APEX1, PDIA6, TUFM, UGP2, FHL1, ISOC1, BCAP31, BUB1B, MAD2L1, COPS6, ATP5C1, PPIA, CYFIP1, ACAA2, CYB5A, CCNB2, TTK, GMNN, POLE2, GLO1, PRDX3, IDH2, MRPS35, KDELR2, DYNLL1, ATP5L, BIRC5 |
| KEGG GLUTATHIONE METABOLISM | GSTA4, GSTM1, MGST3, IDH1, GSTM5, GSTM2 |
| PAL PRMT5 TARGETS UP | SET, 2310003F16RIK, ARL2BP, PRKCDBP, TMPO, NDUFB8, PSMC3, FKBP4, NCBP2, MRPL20, EMP3, TSEN34, CCNB2, TTK, APEX1, GMNN, PTOV1, PSMD6, TUFM, POLE2, GUSB, TARDBP, ECH1, TUBB2A, LSM2, NDE1, CAPG, ERH |
| KEGG PROPANOATE METABOLISM | HIBCH, PCCB, ALDH3A2, HADHA, SUCLG1 |
| REACTOME CHOLESTEROL BIOSYNTHESIS | FDFT1, IDI1, HMGCS1, MVK, DHCR7, DHCR24, NSDHL |
| GRAHAM CML DIVIDING VS NORMAL QUIESCENT UP | BUB1B, CCNE1, ESPL1, ELOVL6, PRDX4, CCNB1, LMNA, CENPA, TST, SFXN1, MRPS15, CCNA2, CCNB2, TTK, GMNN, POLE2, ACOT7, RNASEH2A, TK1, PMP22, TUBB6, IDH2, NT5DC2, BIRC5 |
| ROSTY CERVICAL CANCER PROLIFERATION CLUSTER | BUB1B, ESPL1, MAD2L1, MLF1IP, TMPO, PLK1, CCNB1, CENPA, ASF1B, MRPS15, CCNA2, CDCA3, SAC3D1, CCNB2, TTK, GMNN, TK1, DPP3, BIRC5, EBP |
| REACTOME CELL CYCLE MITOTIC | |
| KEGG CITRATE CYCLE TCA CYCLE | |
| SCHLOSSER SERUM RESPONSE AUGMENTED BY MYC | |
| FLECHNER BIOPSY KIDNEY TRANSPLANT REJECTED VS OK DN | |
| GRADE COLON CANCER UP | |
| KEGG FATTY ACID METABOLISM | |
| BORCZUK MALIGNANT MESOTHELIOMA UP | |
| REACTOME DARPP32 EVENTS | |
| RHODES UNDIFFERENTIATED CANCER | |
| WHITEFORD PEDIATRIC CANCER MARKERS | |
| ALONSO METASTASIS UP | |
| LANDIS ERBB2 BREAST TUMORS 324 DN | |
| LEE EARLY T LYMPHOCYTE UP | |
| HORIUCHI WTAP TARGETS DN | |
| HUANG DASATINIB RESISTANCE DN | |
| ODONNELL TARGETS OF MYC AND TFRC DN | |
| IVANOVA HEMATOPOIESIS INTERMEDIATE PROGENITOR | |
| ZHAN MULTIPLE MYELOMA PR UP | |
| SANA RESPONSE TO IFNG DN | |
| CAFFAREL RESPONSE TO THC DN | DNAJA1, TMEM109, CCNA2 |
| CORUM F1F0-ATP SYNTHASE EC 3.6.3.14 MITOCHONDRIAL | ATP5E, ATP5O, ATP5A1, ATP5I, ATP5C1, ATP5J2, ATP5J, ATP5L |
| LOPEZ MBD TARGETS | |
| NATSUME RESPONSE TO INTERFERON BETA DN | |
| BANDRES RESPONSE TO CARMUSTIN WITHOUT MGMT 48HR DN | |
| NUYTTEN EZH2 TARGETS DN | |
| MARKEY RB1 ACUTE LOF DN | |
| LIU CMYB TARGETS UP | |
| REACTOME METABOLISM OF PROTEINS | |
| HOFFMANN LARGE TO SMALL PRE BII LYMPHOCYTE UP | |
| REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | |
| CASORELLI ACUTE PROMYELOCYTIC LEUKEMIA DN | |
| KEGG TERPENOID BACKBONE BIOSYNTHESIS | |
| KEGG BIOSYNTHESIS OF UNSATURATED FATTY ACIDS | |
| CROONQUIST NRAS SIGNALING DN | |
| LI AMPLIFIED IN LUNG CANCER | |
| REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | ATP5E, ATP5O, ATP5A1, ATP5I, ATP5C1, ATP5J2, ATP5J, ATP5L |
| KEGG BUTANOATE METABOLISM | |
| BIOCARTA TFF PATHWAY | |
| PENG LEUCINE DEPRIVATION DN | |
| UDAYAKUMAR MED1 TARGETS UP | |
| XU HGF SIGNALING NOT VIA AKT1 48HR DN | |
| SESTO RESPONSE TO UV C6 | |
| PENG GLUTAMINE DEPRIVATION DN | |
| CORUM RNA POLYMERASE II COMPLEX CHROMATIN STRUCTURE MODIFYING | |
| SCIBETTA KDM5B TARGETS DN | |
| REACTOME TRANSFORMATION OF LANOSTEROL TO CHOLESTEROL | |
| REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | |
| FARMER BREAST CANCER APOCRINE VS BASAL | |
| REACTOME CHAPERONIN MEDIATED PROTEIN FOLDING | |
| TAKAO RESPONSE TO UVB RADIATION UP | |
| REACTOME GLUTATHIONE CONJUGATION | |
| CROMER METASTASIS DN | |
| NCI TRANSFORMATION OF LANOSTEROL TO CHOLESTEROL | |
| GALE APL WITH FLT3 MUTATED DN | |
| KEGG PEROXISOME | |
| MORI PLASMA CELL UP | |
| HONMA DOCETAXEL RESISTANCE | |
| MORI IMMATURE B LYMPHOCYTE DN | |
| KEGG PARKINSONS DISEASE | |
| BIOCARTA RAS PATHWAY | |
| KEGG HUNTINGTONS DISEASE | |
| ELLWOOD MYC TARGETS DN | |
| LEE LIVER CANCER SURVIVAL DN | |
| REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | |
| MUELLER PLURINET | |
| REACTOME DIABETES PATHWAYS | |
| DAIRKEE TERT TARGETS UP | |
| BIOCARTA MCALPAIN PATHWAY | |
| TARTE PLASMA CELL VS B LYMPHOCYTE UP | |
| RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY UP | |
| CHEN HOXA5 TARGETS 9HR DN | |
| KAAB FAILED HEART ATRIUM DN | |
| REACTOME REGULATION OF INSULIN SECRETION | |
| WAMUNYOKOLI OVARIAN CANCER LMP UP | |
| BIOCARTA NOS1 PATHWAY | |
| YU MYC TARGETS UP | |
| CHIANG LIVER CANCER SUBCLASS UNANNOTATED DN | |
| CROONQUIST IL6 DEPRIVATION DN | |
| TIMOFEEVA GROWTH STRESS VIA STAT1 DN | |
| GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS TURQUOISE DN | |
| MORI LARGE PRE BII LYMPHOCYTE UP | |
| ACEVEDO NORMAL TISSUE ADJACENT TO LIVER TUMOR DN | |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 16 | |
| BIOCARTA AKAP95 PATHWAY | |
| NUYTTEN NIPP1 TARGETS DN | |
| OUELLET CULTURED OVARIAN CANCER INVASIVE VS LMP UP | |
| REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS | |
| NCI FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | |
| LANDIS ERBB2 BREAST PRENEOPLASTIC DN | |
| KEGG PYRUVATE METABOLISM | |
| CORUM OLIGOSACCHARYLTRANSFERASE COMPLEX STT3B VARIANT | |
| HSIAO HOUSEKEEPING GENES | |
| REACTOME PHASE II CONJUGATION | |
| BENPORATH PROLIFERATION | |