| Gene Set | Leading Edge Genes |
|---|
| REN ALVEOLAR RHABDOMYOSARCOMA DN | SEMA3C, TGFBR2, BACE1, FSTL1, SEC61B, PTRF, GALNT1, S100A13, ALG5, EPHX1, ADAM10, IGFBP3, PDLIM5, IQGAP1, ARPC5, OSBPL3, FZD1, UGDH, NTAN1, NQO1, PKD2, TMOD3, TRAM2, LXN, PDLIM2, CAV1, CLIC1, PAPSS1, CMTM6, CCND1, EFEMP1, ACTR2, TSPO, NRP1, ARPC3, TUSC3, GNAI2, SKAP2 |
| RHEIN ALL GLUCOCORTICOID THERAPY DN | SCCPDH, CETN2, MLF1IP, DUSP6, MRPS33, SPARC, E2F8, TBCA, CKS1B, APEX1, TUBB, CPNE3, ATP5J, TMEM14A, UGP2, SSBP1, PKD2, ING2, MELK, DCTD, LXN, DPYSL2, GPR125, CD9, ACAA2, ACADM, CYB5A, NAP1L1, RACGAP1, PIGP, PTTG1, POLE2, ANP32A, PRDX3, PRDX1, SNRPD2, IDH2 |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 17 | GCLM, FKBP1A, ARL2BP, NDUFV2, COPE, ALG5, EI24, ALDH9A1, MRPS15, PSMA7, NAP1L1, ARPC5, CKS1B, BPGM, TCP1, BAG1, GSTP1, POLR3K, DDT, DPP3, USP1, CORO1C, MRPS14 |
| PAL PRMT5 TARGETS UP | KIF20A, ARL2BP, NDUFA13, FSTL1, HN1, PRKCDBP, CALM3, CETN2, TMPO, STMN1, SFRS6, H2AFX, ANAPC5, ANP32E, MRPL20, CKS1B, APEX1, RACGAP1, PSMD6, KIF23, CDC25C, POLE2, PKD2, COPS3, H2AFV, CFDP1, TACC3, TUBB2A, EIF4G2, LSM2, RCN2, NDE1 |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 13 | ATP5O, NDUFA13, SSNA1, NDUFA3, CHMP2A, PSMA5, ATP5J, GUK1, CCND1, MRPS33, UBL5, MTMR9, POLR3K, MRPL28, DBI |
| REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | ADD1, CASP6, VIM, CASP3 |
| NCI CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | ADD1, CASP6, VIM, CASP3 |
| LEE LIVER CANCER SURVIVAL DN | RPL35, CLIC1, HN1, CCNB1, CCNA2, CENPF, NAP1L1, SNRPB2, CALM2, RGS2, CCT5, PTMA, USP1, CTBP2, LXN, RPS3 |
| CORUM TRBP CONTAINING COMPLEX DICER RPL7A EIF6 MOV10 AND SUBUNITS OF THE 60S RIBOSOMAL PARTICLE | |
| NCI FORMATION OF A POOL OF FREE 40S SUBUNITS | RPS15A, RPL35, RPL4, RPS11, RPLP1, RPL3L, RPS3A, RPS10, RPS21, RPS5, RPS16, RPL23, RPS23, RPS19, RPL11, RPL30, RPS7, RPL19, RPL6, RPS2, RPL39, RPLP2, RPL15, RPS8, RPL37, RPL31, RPL13A, RPL7, RPS24, RPS3 |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 12 | |
| OHASHI AURKB TARGETS | |
| REACTOME PEPTIDE CHAIN ELONGATION | RPS15A, RPL35, RPL4, RPS11, RPLP1, RPL3L, RPS3A, RPS10, RPS21, RPS5, RPS16, RPL23, RPS23, RPL11, RPS19, RPL30, RPS7, RPL19, RPL6, RPS2, RPL39, RPLP2, RPL15, RPS8, RPL37, RPL31, RPL13A, RPL7, RPS24, RPS3 |
| NCI VIRAL MRNA TRANSLATION | RPS15A, RPL35, RPL4, RPS11, RPLP1, RPL3L, RPS3A, RPS10, RPS21, RPS5, RPS16, RPL23, RPS23, RPL11, RPS19, RPL30, RPS7, DNAJC3, RPL19, RPL6, RPS2, RPL39, RPLP2, RPL15, RPS8, RPL37, RPL31, RPL13A, RPL7, RPS24, RPS3 |
| REACTOME VIRAL MRNA TRANSLATION | RPS15A, RPL35, RPL4, RPS11, RPLP1, RPL3L, RPS3A, RPS10, RPS21, RPS5, RPS16, RPL23, RPS23, RPL11, RPS19, RPL30, RPS7, DNAJC3, RPL19, RPL6, RPS2, RPL39, RPLP2, RPL15, RPS8, RPL37, RPL31, RPL13A, RPL7, RPS24, RPS3 |
| REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | FOXA2, RPS11, RPL3L, RPS3A, RPS16, RPL23, RPL6, RPS2, RPL39, RPS8, RPL37, RPL13A, RPS3, RPS15A, RPL35, RPL4, RPLP1, RPS10, RPS5, RPS21, RPS23, RPS19, RPL11, RPL30, RPS7, RPL19, RPLP2, RPL15, RPL31, RPS24, RPL7, PAX6 |
| NCI GTP HYDROLYSIS AND JOINING OF THE 60S RIBOSOMAL SUBUNIT | RPS15A, RPL35, RPL4, RPS11, RPLP1, RPL3L, RPS3A, RPS10, RPS21, RPS5, RPS16, RPL23, RPS23, RPL11, RPS19, RPL30, RPS7, RPL19, RPL6, RPS2, RPL39, RPLP2, RPL15, RPS8, RPL37, RPL31, RPL13A, RPL7, RPS24, RPS3 |
| YANG BREAST CANCER ESR1 BULK UP | |
| NCI CAP DEPENDENT TRANSLATION INITIATION | RPS15A, RPL35, RPL4, RPS11, RPLP1, RPL3L, RPS3A, RPS10, RPS21, RPS5, RPS16, RPL23, RPS23, RPL11, RPS19, RPL30, RPS7, RPL19, RPL6, RPS2, RPL39, RPLP2, RPL15, RPS8, RPL37, RPL31, RPL13A, RPL7, RPS24, RPS3 |
| NCI EUKARYOTIC TRANSLATION TERMINATION | RPS15A, RPL35, RPL4, RPS11, RPLP1, RPL3L, RPS3A, RPS10, RPS21, RPS5, RPS16, RPL23, RPS23, RPS19, RPL11, RPL30, RPS7, RPL19, RPL6, RPS2, RPL39, RPLP2, RPL15, RPS8, RPL37, RPL31, RPL13A, RPL7, RPS24, RPS3 |
| NCI PEPTIDE CHAIN ELONGATION | RPS15A, RPL35, RPL4, RPS11, RPLP1, RPL3L, RPS3A, RPS10, RPS21, RPS5, RPS16, RPL23, RPS23, RPL11, RPS19, RPL30, RPS7, RPL19, RPL6, RPS2, RPL39, RPLP2, RPL15, RPS8, RPL37, RPL31, RPL13A, RPL7, RPS24, RPS3 |
| REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | RPS11, RPS3A, RPS2, RPS10, RPS8, RPS5, RPS21, RPS24, RPS3, RPS23, RPS19 |
| NCI FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | RPS11, RPS3A, RPS2, RPS10, RPS8, RPS5, RPS21, RPS24, RPS3, RPS23, RPS19 |
| WIKMAN ASBESTOS LUNG CANCER UP | |
| KEGG RIBOSOME | RPS15A, RPL35, RPL4, RPS11, RPLP1, RPL3L, RPS3A, RPS10, RPS21, RPS5, RPS16, RPL23, RPS23, RPS19, RPL11, RPL30, RPS7, RPL19, RPL6, RPS2, RPL39, RPLP2, RPL15, RPS8, RPL37, RPL31, RPL13A, RPL7, RPS24, RPS3 |
| CORUM 40S RIBOSOMAL SUBUNIT CYTOPLASMIC | RPS11, RPS3A, RPS2, RPS10, RPS8, RPS5, RPS21, RPS24, RPS3, RPS23, RPS19 |
| REACTOME INSULIN SYNTHESIS AND SECRETION | RPL35, RPS11, SEC61B, RPLP1, RPS3A, RPS10, RPS21, RPS5, RPS23, RPS19, RPL30, SRP9, SLC30A5, RPL6, SPCS2, RPS2, RPL39, RAB27A, RPS8, RPL37, RPL31, SRP19, RPS24, GNAI2, PAX6, RPS3 |
| REACTOME GTP HYDROLYSIS AND JOINING OF THE 60S RIBOSOMAL SUBUNIT | RPS15A, RPL35, RPL4, RPS11, RPLP1, RPL3L, RPS3A, RPS10, RPS21, RPS5, RPS16, RPL23, RPS23, RPL11, RPS19, RPL30, RPS7, RPL19, RPL6, RPS2, RPL39, RPLP2, RPL15, RPS8, RPL37, RPL31, RPL13A, RPL7, RPS24, RPS3 |
| REACTOME REGULATION OF BETA CELL DEVELOPMENT | |
| CHANG CYCLING GENES | ARL4A, LMNB1, ILF2, KIF23, CDC25C, TSN, CCNF, CENPA, ASF1B, MELK, TACC3, PSRC1, USP1 |
| REACTOME RNA POLYMERASE I PROMOTER OPENING | H2AFX |
| REACTOME FORMATION OF A POOL OF FREE 40S SUBUNITS | RPS15A, RPL35, RPL4, RPS11, RPLP1, RPL3L, RPS3A, RPS10, RPS21, RPS5, RPS16, RPL23, RPS23, RPS19, RPL11, RPL30, RPS7, RPL19, RPL6, RPS2, RPL39, RPLP2, RPL15, RPS8, RPL37, RPL31, RPL13A, RPL7, RPS24, RPS3 |
| CORUM 60S RIBOSOMAL SUBUNIT CYTOPLASMIC | |
| REACTOME TRANSLATION | RPS11, EEF1B2, RPL3L, RPS3A, RPS16, RPL23, RPL6, RPS2, RPL39, RPS8, RPL37, RPL13A, RPS3, PABPC1, RPS15A, RPL35, RPL4, RPLP1, RPS10, RPS5, RPS21, RPS23, RPS19, RPL11, RPL30, RPS7, RPL19, RPLP2, RPL15, RPL31, RPS24, RPL7 |
| CORUM RIBOSOME CYTOPLASMIC | RPS15A, RPL35, RPL4, RPS11, RPLP1, RPS3A, RPS10, RPS21, RPS5, RPS16, RPL23, RPS23, RPS19, RPL11, RPL30, RPS7, RPL19, RPL6, RPS2, RPL39, RPLP2, RPL15, RPS8, RPL37, RPL31, RPL13A, RPL7, RPS24, RPS3 |
| AMUNDSON GAMMA RADIATION RESPONSE | CCNB2, MAD2L1, CDKN2C, PTTG1, KIF23, CDC25C, CCNB1, TSN, CCNF, CENPA, TACC3, H2AFX, CCNA2 |
| NCI L13A MEDIATED TRANSLATIONAL SILENCING OF CERULOPLASMIN EXPRESSION | RPS15A, RPL35, RPL4, RPS11, RPLP1, RPL3L, RPS3A, RPS10, RPS21, RPS5, RPS16, RPL23, RPS23, RPL11, RPS19, RPL30, RPS7, RPL19, RPL6, RPS2, RPL39, RPLP2, RPL15, RPS8, RPL37, RPL31, RPL13A, RPL7, RPS24, RPS3, PABPC1 |