| Gene Set | Leading Edge Genes |
|---|
| DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP | CDC16, POLE3, YY1, POLR2B, SLBP, EI24, UBE2V2, BTBD1, BECN1, ALDH4A1, FECH, TERF1, HS2ST1, YME1L1, BNIP3, CCDC6, DCTN4, CDC5L, MED6, LMAN1, MARCH6, ADCY7, SEPHS2, CUL4B, SSB, PRKRA, LIN7C, WDR61, SMAD4, MRPS35, TUBGCP3, ZMYND11, RAD1, PRKRIR, DNAJC12, PIK3C3, GART, TIMM17A, SMC2, MED4, NCBP2, SS18, SPTLC1, ARCN1, TOPBP1, SEC23IP, CBFB, TFRC, EBAG9, PPA2, OXSR1, IPO7, F2R, PDHB, CASP6, PAICS, COPS2, RCL1, ABL1, ATP2A2, SCARB2, UBE2B, EIF4ENIF1, ACADM, COIL, ATP6V1B2, PNN, CASP8, CSNK1A1, UBE2E3, GTF2H1, HDAC2, IMPA1, EIF1B, SRP19, ZFR, MAP1LC3B, RAB31, PPP2CB, ARHGEF3, GBAS, ALG5, LSM1, TCF12, MRPS30, B3GALNT1, CHERP, RBM5, SERPINE2, ACTL6A, C1D, PLAA, SUCLA2, CNIH, UBE4B, STAG2, CTCF, CD2AP, MBD4, ARL5A, DPM1, CCT6A, AMD1, FOXK2, EPS15, API5, YTHDF2, GMNN, PPP4R1, PUS1, CYP51A1, MRE11A, IKBKAP, GMFB, CLPX, SMC4, USP1, SDHD, SLC7A5, UPF1, RNF6, CASP8AP2, SFRS3, SNW1, BRD1, NDUFA5, ATG12, DBF4, RAD21, SEC31A, UCHL5, NAP1L4, CAB39, RREB1, AHCYL1, GARS, PDCD2, TMEM165, BCKDHB, PGRMC2, PSTPIP2, UPF3B, UBP1, NFE2L2, SNRPB2, MSH6, LBR, RNASEH1, PCNP, OAT, ZMPSTE24, TBPL1, NSMAF, CDK8 |
| WEI MYCN TARGETS WITH E BOX | DYNLT3, PKNOX1, POLE3, QSER1, MBP, MRPS30, EGLN1, LSG1, SERPINE2, UPF2, SFRS7, HS2ST1, RABGGTB, GRPEL1, ISOC1, SPCS3, CTPS, GOLT1B, ARL5A, CCT6A, AMD1, TMEM70, MRPS28, PTS, RPP40, GMNN, PUS1, NUP37, TSN, TIMM50, MRPS35, TIMM17A, SBNO1, SMC2, ORC6L, SLC20A1, AHCTF1, NEDD4, MRPL19, TAF1A, PPIF, CBFB, TFRC, PAPOLA, SERBP1, EXOSC9, CCNE1, LACTB2, PAICS, LPGAT1, ERGIC2, GTF3C4, HELLS, RCL1, ATP2A2, PTPLAD1, TNPO3, ANP32E, PTDSS1, HTR3A, CASP8, RNASEH1, ERO1L, OAT, ZMPSTE24, POP7, DAPK3, SRP19, SLC39A6 |
| TIEN INTESTINE PROBIOTICS 24HR UP | SFRS3, NDUFA5, TAF11, TMPO, NIP7, DBF4, SLBP, EI24, HSPE1, SHCBP1, FBXO3, RECQL, RDH11, TOPBP1, BCLAF1, C1D, PPIF, NR2F2, ENTPD4, SFRS7, AGPAT5, TNPO1, SUCLA2, PDHB, UBE2D1, KLHL21, AMD1, EED, MRPS28, ANP32E, PTS, GMNN, MSH6, PNN, ZFYVE16, PTPLB, KIF23, TSN, DNAJC9, TM7SF3, RBM8A, SMC4, DYNLL1 |
| SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN DN | MAP1LC3B, CDC16, CLOCK, POLE3, TTC3, MYST3, TIMM17A, POLR2B, EGLN1, RBM5, RHOQ, BECN1, GARS, C1D, OXSR1, CNIH, YME1L1, IPO7, CCDC6, TRIM44, GBP1, MBD4, ARL5A, MED6, MCM3AP, LMAN1, CUL4B, ATP6V1B2, E2F6, SNRPB2, NFE2L2, PTDSS1, PSPH, EIF2AK3, CCNC, PEX12, USP1, CAP1, RAD1, ZFR |
| SCHLOSSER MYC TARGETS REPRESSED BY SERUM | POLE3, HSPD1, COPS2, IDH3A, YY1, CSNK1E, EI24, SEC31A, HSPE1, CHERP, ACTL6A, EXOSC8, PDIA6, GARS, SSB, RMND5A, NR2F2, OAT, ZMPSTE24, HDAC2, SERBP1, RABGGTB, SLC39A6, IARS |
| RAMALHO STEMNESS UP | SEC23A, RRN3, SFRS3, ACADM, BLZF1, ARCN1, SEC23IP, LSG1, FBXO38, ZCCHC10, GARS, PDCD2, PKD2, TNPO1, INTS5, ZFX, IARS, F2R |
| LINDGREN BLADDER CANCER WITH LOH IN CHR9Q | PSMD5, TOR1A, POLE3, STX17, ABL1, CAMSAP1, SPTLC1, IPPK, TRIM32, MIS12, DUSP22, RABGAP1, RXRA, RAB14, TOR1B, RNF38, IARS |
| PUJANA CHEK2 PCC NETWORK | POLE3, HSPD1, TAF11, TMPO, PAXIP1, YY1, LSM1, SLBP, POLR2B, HSPE1, CHERP, ACTL6A, EXOSC8, C1D, CHUK, HS2ST1, CNIH, CTCF, CD2AP, CTPS, DPM1, MED6, EED, SNRPA1, SSB, PRKRA, DNAJC9, MRE11A, CLPX, SMC4, USP1, SLC7A5, SFRS11, IARS, RAD1, SSBP2, SFRS3, PRKRIR, ATG12, DBF4, RAD21, TIMM17A, SMC2, RB1CC1, ELAC2, NCBP2, SEC31A, RECQL, NAP1L4, TOPBP1, TOP2A, CNOT1, MRPL19, METAP1, CBFB, TFRC, RMND5A, POLG, DDX39, OXSR1, WTAP, ATR, PAICS, ADNP, ANP32E, EZH2, SNRPB2, MSH6, PNN, LBR, POLR3G, GLMN, RNASEH1, POT1, HDAC2, SRP19, CCNC, NUP62 |
| ZHANG BREAST CANCER PROGENITORS UP | RNF6, CASP8AP2, SFRS3, TTC3, TMPO, DBF4, RAD21, SBNO1, TIMM17A, LPHN3, SMC2, POLR2B, SHCBP1, TOP2A, TOPBP1, ACTL6A, C1D, TFRC, UGDH, SERBP1, SUCLA2, CTCF, CD2AP, ATR, IDH3A, HELLS, MED6, UBE2B, MARCH6, SLC20A2, SEPHS2, ANP32E, PCMTD2, CNOT6, EZH2, SNRPB2, HBXIP, ECT2, GMNN, ZCCHC8, SSB, DNAJC9, USP1, SMC4, LRRC40, PCYOX1 |
| BORCZUK MALIGNANT MESOTHELIOMA UP | DYNLT3, CREBBP, SFRS3, UBE2D1, LPGAT1, TAF11, RAD21, ATP2A2, NCBP2, ADNP, SEC23IP, HBXIP, ACTL6A, MSH6, GARS, PAPOLA, PTPLB, UBE2E3, WTAP, TNPO1, SERBP1, SMC4, IPO7, SMAD4, F2R, ZMYND11, RAD1 |
| STEARMAN LUNG CANCER EARLY VS LATE UP | CTCF, RNF6, CLOCK, LIMS1, UPF3B, WWC2, DPM1, KDR, SCARB2, UBE2V2, OSBPL11, APBB2, PDGFA, PNN, PKD2, AGPAT5, CLK1, TM7SF3, SMAD4 |
| PUJANA XPRSS INT NETWORK | CTCF, SSBP2, SFRS3, PAICS, TAF11, TMPO, PAXIP1, RAD21, SMC2, POLR2B, TOP2A, TOPBP1, ANP32E, SNRPA1, EZH2, PNN, EXOSC8, LBR, DDX39, DNAJC9, SMC4, USP1 |
| DING LUNG CANCER EXPRESSION BY COPY NUMBER | PDCD6, ANKRD46, TERF1, RB1CC1, LSM1, CDK8, ARMC1, FBXO3, MRPS28, THUMPD1 |
| BOGNI TREATMENT RELATED MYELOID LEUKEMIA DN | ZFYVE26, CD2AP, CDK8, DDX17 |
| REACTOME GENERIC TRANSCRIPTION PATHWAY | MED4, CDK8, CREBBP, CCNC, SNW1, NOTCH1, MED6 |
| MOREAUX MULTIPLE MYELOMA BY TACI DN | ZCCHC10, BTBD1, TTRAP, ACTL6A, MRPL19, MBD4, PAK1IP1, ABHD3, TERF1, DBF4, MCM3AP, TMEM165, IFT74, SLC33A1, LRRC40, IARS, EZH2 |
| REACTOME RNA POLYMERASE I PROMOTER ESCAPE | |
| NCI RNA POLYMERASE I PROMOTER CLEARANCE | |
| REACTOME MRNA 3 END PROCESSING | SFRS7, RNPS1, NCBP2, SFRS3, RBM8A, PAPOLA, UPF3B, SFRS11 |
| GINESTIER BREAST CANCER ZNF217 AMPLIFIED UP | |
| CHOI ATL CHRONIC VS ACUTE DN | |
| BROWNE HCMV INFECTION 14HR UP | |
| ZHANG RESPONSE TO IKK INHIBITOR AND TNF DN | |
| RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED UP | |
| CORUM RNA POLYMERASE II COMPLEX CBP PCAF RPB1 BAF47 CYCC CDK8 CHROMATIN STRUCTURE MODIFYING | |
| NCI CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION | SFRS7, RNPS1, NCBP2, SFRS3, RBM8A, PAPOLA, UPF3B, SFRS11 |
| KINSEY TARGETS OF EWSR1 FLII FUSION UP | |
| NCI RNA POLYMERASE I PROMOTER ESCAPE | |
| UDAYAKUMAR MED1 TARGETS UP | |
| CORUM SPLICEOSOME | SFRS3, BCAS2, SNW1, PRPF3, SPEN, NCBP2, SNRPA1, SNRPB2, SYF2, CRNKL1, SFRS7, RNPS1, WTAP, PRPF4B, RBM8A, DDX17, SFRS11 |
| CORUM POSTSPLICING COMPLEX | |
| REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | |
| NCI MRNA 3 END PROCESSING | SFRS7, RNPS1, NCBP2, SFRS3, RBM8A, PAPOLA, UPF3B, SFRS11 |