| Gene Set | Leading Edge Genes |
|---|
| FLECHNER BIOPSY KIDNEY TRANSPLANT REJECTED VS OK DN | DYNLT3, CA2, PRPF40A, HSPD1, ACY1, PRKAR1A, YES1, RHOBTB3, OXCT1, BRP44, ATP5O, ABCD3, BBOX1, FGF1, PEBP1, UGDH, CRYAB, DDT, RABGGTB, CNIH, AGL, PEX7, EHHADH, ALDH9A1, DCI, CYB5A, CYCS, NDUFS4, IGFBP5, PRDX3, PEX19, PPM1B, HIBCH, IDH2, FABP1, SC5DL, AHCY, SLC16A7, ASS1, COMT, KHK, MME, ATP5A1, MDH1, HAGH, ANK3, SLC25A4, GCDH, RPP14, ZNF148, PDHX, BCKDHB, PGRMC2, ABAT, GOT1, DLD, SDHB, DDX10, SNRPN /// SNURF, GRB14, GSTA2, ACO2, IGSF3, PTPRD, MAOA, FMO1, CTH, GRHPR, CALM1, MAOB, ASPA, DDOST, QDPR |
| RHEIN ALL GLUCOCORTICOID THERAPY DN | ARPC5L, NME1, INTS8, SCCPDH, PRDX4, CDK4, OXCT1, ENO1, TYMS, HMGN2, BLMH, HDDC2, MCM5, UGP2, CHEK1, METTL5, KIF11, COPS6, MTHFD1, MCM2, VDAC1, TBC1D4, CYB5A, DUT, PCCB, NUDT1, ME2, UNG, THOC7, GLO1, PRDX3, RPA1, IDH2, SHMT2, RRM2, AHCY, RSL1D1, STOML2, ERG, NDUFB5, MME, MDH1, PDIA6, PDCD2, CCT8, TUFM, TMEM14A, BCCIP, TMEM135, AK2, ING2, UQCRC2, FHL1, DHFR, ATP5C1, ITGB3BP, ATIC, HMMR, ACAA2, TPI1, ANP32E, PCMT1, CCNB2, TTK, POLE2, CALM1, CCT7, DARS, PRIM1, ATP5L |
| KAAB HEART ATRIUM VS VENTRICLE DN | SDHA, MCCC2, ELAC2, BDH1, ASS1, HIST1H1C, COQ9, ABLIM1, ATP5A1, TSFM, NDUFS6, CPVL, PDHX, NDUFS2, GPT, NDUFV2, DLD, ATP5C1, SDHB, SLC5A1, KCNJ8, VDAC1, MPPED2, GADD45A, AMD1, TBC1D4, DCI, OGDH, CYB5A, AZGP1, NDUFA9, UNG, HEBP2, ATP1B1, MAOB, CCT7, PRDX3, ACADS, GCAT, IDH2, UBE3A, HIST2H2BE, OPA1, STARD7 |
| NETPATH ANDROGEN RECEPTOR PATHWAY UP | PIP, CA2, FKBP11, SCAP, PRDX4, ELL2, RPN2, CDK4, BRP44, ABCD3, FDPS, PPIB, DDT, GCS1, PPAP2A, SPCS3, ARG2, HSD17B3, GNPNAT1, TGFB2, AMD1, LMAN1, HOMER2, TXNDC5, SPDEF, AZGP1, TRAM1, ARF4, HEBP2, MKLN1, IGFBP5, PKIB, IDI1, HSD17B4, SAR1B, HPGD, CCNB1, SLC33A1, KLK4, MCCC2, RBM10, SLC38A5, ABCA5, SEC24A, PMM2, SF3B5, SSR4, RAB4A, THYN1, FST, CBWD1, SLC22A3, GOT1, COPS7A, UAP1, SSR3, MAK, SEMA5A, SLC35B1, MGLL, RPN1, UFM1, CTH, HES6, APPBP2, HIGD1A, PGM3, PDIA5, ERO1L, KDELR3, SRP19 |
| CHIANG LIVER CANCER SUBCLASS PROLIFERATION DN | GPT, MLYCD, ADH4, FMO3, MTHFD1, CPB2, ST3GAL6, DHRS1, CPT2, EHHADH, AASS, CTH, GRHPR, GNE, HAGH, DCXR, GPT2, GCDH, ADH1A, ABAT |
| ZHANG BREAST CANCER PROGENITORS UP | PIN1, A630043P06, ACTR6, SFPQ, CSTF2, E2F7, TMEM33, PBK, PSAT1, NUDCD1, OXCT1, C630043F03RIK, ABHD13, ACTL6A, PSPC1, VPS26B, UGDH, ZFP422-RS1, DSG2, CHEK1, ACYP1, SUCLA2, XPO1, PANK1, NDUFC1, IPO8, CRLS1, MTHFD1, PEX7, MCM2, UTP15, VDAC1, PHF6, CAR12, NDUFS4, UNG, ENPP3, DNAJC9, PPM1B, RPA1, PHB2, PCYOX1, STARD7, PKP4, RRM2, PHF17, AHCY, TSPAN13, RNMT, RPE, UCHL5, ORC5L, SYNCRIP, MDH1, SESN3, KCNB1 /// PACSIN2, SNX5, BET1, WDR75, SLC38A1, HNRPLL, KCTD15, B230118H07RIK, STRBP, SEMA5A, INTS2, HELLS, ZFP367, RPA3, USP34, CCNA2, CTH, RNF7, 5730494N06RIK, APPBP2, 2310001A20RIK, POLR3K, 3110073H01RIK |
| KEGG CITRATE CYCLE TCA CYCLE | MDH1, DLST, DLD, PDHB, SDHB, PDHA1, SUCLG1, SDHA, ACO2, SUCLA2, IDH2, SUCLG2, OGDH |
| RODWELL AGING KIDNEY NO BLOOD DN | GSTA4, UAP1, SLC16A7, MTO1, RHOBTB3, DBT, OXCT1, CYB5A, AASS, CTH, PET112L, ATP5A1, SRP9, CYCS, PEBP1, DSG2, PRDX3, BCKDHB, AK2, PPP2R1B |
| KEGG PROPANOATE METABOLISM | MLYCD, PCCB, MCEE, ACSS2, SUCLG1, EHHADH, ALDH9A1, HIBCH, SUCLA2, ACSS1, ABAT |
| KEGG PYRUVATE METABOLISM | GLO1, MDH1, GRHPR, DLD, HAGH, ALDH9A1, PKM2, ACSS2, ACSS1 |
| GRAHAM CML DIVIDING VS NORMAL QUIESCENT UP | SHMT2, CEP76, RAB31, RRM2, PRDX4, CCNB1, CENPA, PDSS1, PBK, MCM10, HIST1H1C, SFXN1, ARHGAP19, CLEC11A, TYMS, SYNCRIP, ABCD3, MCM5, GSPT1, CHEK1, SAMM50, SUCLA2, TPM1, KIF11, DHFR, MCM2, CSE1L, ITGB3BP, RPA3, HMMR, MRPS28, MRPS15, CCNA2, DUT, TTK, PF4, CCNB2, CPOX, NUDT1, CCNE2, POLE2, IDH2, NT5DC2 |
| REACTOME CITRIC ACID CYCLE | DLST, DLD, SDHB, SDHA, SUCLG1, ACO2, IDH2, SUCLA2, SUCLG2, OGDH |
| RODWELL AGING KIDNEY DN | CTH, ATP5A1, CYCS, PEBP1, SLC16A7, MTO1, RHOBTB3, BCKDHB, AK2, DBT, OXCT1, CCDC93, AASS |
| REACTOME PYRUVATE METABOLISM AND TCA CYCLE | PDHX, DLST, ACO2, DLD, PDHB, SDHB, SUCLA2, OGDH, SUCLG1 |
| LANDIS ERBB2 BREAST PRENEOPLASTIC DN | GSTZ1, MCCC1, ST3GAL6, PDHA1, ALDH1A7, ATP1B3, HADHB, CPT2, BCKDHB, GDPD3, ACAA1B, GPAM, ACAA2 |
| REACTOME VITAMIN B5 (PANTOTHENATE) METABOLISM | COASY, PPCS, PANK3, SLC25A16, PANK1 |
| KEGG FATTY ACID METABOLISM | |
| FERRANDO HOX11 NEIGHBORS | |
| NCI COPI MEDIATED TRANSPORT | |
| CUI GLUCOSE DEPRIVATION | |
| TARTE PLASMA CELL VS B LYMPHOCYTE UP | |
| COLDREN GEFITINIB RESISTANCE UP | |
| HOSHIDA LIVER CANCER SURVIVAL DN | |
| RODRIGUES THYROID CARCINOMA UP | |
| NCI INSULIN SYNTHESIS AND SECRETION | |
| PETRETTO HEART MASS QTL CIS UP | |
| KEGG GLYOXYLATE AND DICARBOXYLATE METABOLISM | |
| KEGG BUTANOATE METABOLISM | |
| REACTOME METABOLISM OF VITAMINS AND COFACTORS | |
| KEGG AMINOACYL TRNA BIOSYNTHESIS | |
| REACTOME ETHANOL OXIDATION | |
| SCHLOSSER MYC TARGETS AND SERUM RESPONSE DN | |
| REACTOME COPI MEDIATED TRANSPORT | |