| Gene Set | Leading Edge Genes |
|---|
| DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP | GMPR2, MAGOH, CETN2, ALG5, TCF12, MRPL3, POLR2B, MRPS30, EI24, CYC1, ICT1, TSPAN4, NDUFA8, AKAP8L, ECHS1, TERF1, KIF22, COPS3, GM2A, BUB3, IDH3B, CCT6A, AMD1, WBSCR22, MATK, SHMT1, RUVBL1, SMC3, AP2M1, NUDT21, CUL4B, PECI, MKRN1, PRKRA, NDUFB6, GLO1, DCTN6, WDR13, PRDX3, FDFT1, QTRT1, HSD17B4, PHB2, MDH2, SQLE, TCERG1, DBF4, GART, NUDC, STOML2, COMT, SS18, NCBP2, PRPS1, UCHL5, ORC5L, TOPBP1, CTNNBL1, FNTA, POLR2E, SLC29A1, CBFB, SSBP1, NDUFAB1, LSM4, DRG2, ZNF22, LSM5, HMBS, SOD1, CCNH, LASS2, PSMC3, RER1, CMAS, HMGB1, LBR, DDX41, DHX9, ZMPSTE24, ANP32A, H2AFV, ATXN10, AUP1 |
| SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN UP | KIF20A, SART1, NDUFB8, GFER, MRPL23, EI24, B4GALT7, NDUFS8, BLOC1S1, STT3A, NSDHL, NDUFB7, UQCRC1, NDUFS6, CDK2AP2, MBD3, CYB5B, BCAT2, VPS4A, CKS2, KIF22, LSM4, BANF1, DUS1L, HMBS, EBP, TCEB2, TAF10, PARK7, NUTF2, HMGB1, PPAN, NDUFA2, PDCD5, PGLS, HEXIM1, PSMD13, UQCRQ, FKBP3, NUBP2, CFDP1, SRP19, PSMB3, HSD17B4, ARHGDIB |
| GRADE COLON CANCER UP | SSNA1, MPG, PEPD, SNRPB, ATP5H, B4GALT7, MCTS1, GADD45GIP1, NDUFS6, APEX1, TUFM, MRP63, SSR2, SSBP1, CKS2, PDIA4, BANF1, BCAP31, EEF1D, NOL7, NAGK, INTS7, TCEB2, IDH3G, PDCD5, HMGB1, RNF7, POLR2F, PYCARD, CCT5, DHX9, MCM7, ANP32A, DDOST, PSMB3, SNRPD2, HSD17B4, MDH2 |
| ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE UP | CETN2, RSRC1, RIOK2, SNRPB, SDF2L1, NUP133, BRP44, STT3A, UFC1, ICT1, THAP11, NDUFA8, APEX1, ACP1, SLC25A4, CKS2, POLR2H, LSM4, DHX16, LRRC42, VAMP5, CUEDC2, MRPL40, RPA3, PPP1CA, CCNA2, MRPL18, PSMD6, NUP37, ANKRD49, DRG1, NDUFB6, WDR61, MRPL48 |
| REACTOME METABOLISM OF RNA | EXOSC8, RAE1, NUP37, DCPS, EXOSC7, NUP93, SNRPD3, SNRPB, NCBP2, LSM4, NUP133, LSM5, EXOSC2 |
| BOYAULT LIVER CANCER SUBCLASS G3 UP | TPRKB, NUP37, CCT5, TSN, TIPIN, ZWILCH, CCT4, ADSL, SNRPD2, TOPBP1, CCNA2 |
| BENPORATH MYC MAX TARGETS | |
| NCI HIV 1 TRANSCRIPTION INITIATION | |
| REACTOME TRANSCRIPTION OF THE HIV GENOME | |
| JIANG HYPOXIA CANCER | |
| NCI RNA POL II CTD PHOSPHORYLATION AND INTERACTION WITH CE | |
| NCI RNA POL II CTD PHOSPHORYLATION AND INTERACTION WITH CE1 | |
| NCI TAT MEDIATED ELONGATION OF THE HIV 1 TRANSCRIPT | |
| NCI PAUSING AND RECOVERY OF ELONGATION | |
| REACTOME RNA POL II CTD PHOSPHORYLATION AND INTERACTION WITH CE | |
| REACTOME CELL CYCLE CHECKPOINTS | |
| NCI RNA POLYMERASE II TRANSCRIPTION PRE INITIATION | |
| REACTOME RNA POLYMERASE II TRANSCRIPTION | POLR2E, POLR2D, MAGOH, POLR2F, TCEB2, TAF10, POLR2H, POLR2B, SSRP1, NCBP2, CSTF1, NUDT21, MNAT1, POLR2J |
| REACTOME NUCLEOTIDE EXCISION REPAIR | |
| REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT | |
| CORUM C COMPLEX SPLICEOSOME | PPIE, MAGOH, SART1, DDX41, SFRS1, SNRPD3, SF3B2, SNRPB, PRPF4B, SF3B3, SNRPD2, AQR |
| NCI HIV 1 ELONGATION ARREST AND RECOVERY | |
| REACTOME GLOBAL GENOMIC NER | |
| REACTOME RNA POLYMERASE I III AND MITOCHONDRIAL TRANSCRIPTION | |
| NCI VIRAL MESSENGER RNA SYNTHESIS | POLR2E, POLR2D, POLR2F, DHX9, POLR2H, SNRP70, SNRPB, POLR2B, NCBP2, POLR2J |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 10 | |
| NCI FORMATION OF THE HIV 1 EARLY ELONGATION COMPLEX | |
| REACTOME TRANSCRIPTION COUPLED NER | |
| KEGG SPLICEOSOME | PRPF31, TCERG1, MAGOH, SART1, SF3B5, SF3B2, SNRPB, LSM4, NCBP2, SNRPD2, DHX16, USP39, THOC1, LSM5, CTNNBL1 |
| NCI MRNA CAPPING | |
| NCI RNA POLYMERASE II TRANSCRIPTION | |
| NCI FORMATION OF THE EARLY ELONGATION COMPLEX | |
| NCI RNA POLYMERASE II TRANSCRIPTION ELONGATION | |
| KEGG PYRIMIDINE METABOLISM | |
| REACTOME VIRAL MESSENGER RNA SYNTHESIS | |
| PENG GLUTAMINE DEPRIVATION DN | |
| NCI HIV 1 TRANSCRIPTION ELONGATION | |
| REACTOME HIV INFECTION | |
| REACTOME TAT MEDIATED HIV1 ELONGATION ARREST AND RECOVERY | |
| NCI PAUSING AND RECOVERY OF TAT MEDIATED HIV 1 ELONGATION | |
| REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX | |
| MOOTHA TCA | |
| NCI FORMATION OF HIV 1 ELONGATION COMPLEX CONTAINING HIV 1 TAT | |
| REACTOME LATE PHASE OF HIV LIFE CYCLE | POLR2D, POLR2F, RAE1, NUP37, TCEB2, CCNH, TAF10, RAN, POLR2H, POLR2B, NUP133, MNAT1, POLR2J |
| CORUM RESPIRATORY CHAIN COMPLEX I INCOMPLETE INTERMEDIATE MITOCHONDRIAL | |
| CORUM 17S U2 SNRNP | |
| NCI ELONGATION ARREST AND RECOVERY | |
| REACTOME RNA POLYMERASE I PROMOTER CLEARANCE | |
| NCI FORMATION OF RNA POL II ELONGATION COMPLEX | |
| KEGG OXIDATIVE PHOSPHORYLATION | |
| KEGG PARKINSONS DISEASE | |
| KEGG HUNTINGTONS DISEASE | |
| NCI ELONGATION OF INTRON CONTAINING TRANSCRIPTS AND CO TRANSCRIPTIONAL MRNA SPLICING | |
| REACTOME INTEGRATION OF ENERGY METABOLISM | |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | |
| REACTOME HIV1 TRANSCRIPTION INITIATION | |
| CORUM 39S RIBOSOMAL SUBUNIT MITOCHONDRIAL | MRPL3, MRPL40, MRPL16, MRPL34, MRPL46, MRPL23, MRPL18, MRPL35 |
| GARY CD5 TARGETS DN | |
| DAIRKEE TERT TARGETS UP | |
| NCI RNA POLYMERASE II PROMOTER ESCAPE | |
| LEE METASTASIS AND RNA PROCESSING UP | |
| NCI ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT | |
| NCI RNA POLYMERASE II TRANSCRIPTION INITIATION | |
| PELLICCIOTTA HDAC IN ANTIGEN PRESENTATION UP | |
| NCI RNA POLYMERASE II HIV 1 PROMOTER ESCAPE | |
| REACTOME REGULATION OF INSULIN SECRETION | |
| NCI PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | |
| CORUM RESPIRATORY CHAIN COMPLEX I LAMBDA SUBUNIT MITOCHONDRIAL | |
| CORUM RNA POLYMERASE II HOLOENZYME COMPLEX | |
| ZHONG RESPONSE TO AZACITIDINE AND TSA DN | |
| REACTOME HIV1 TRANSCRIPTION ELONGATION | |
| CORUM 28S RIBOSOMAL SUBUNIT MITOCHONDRIAL | |
| CHNG MULTIPLE MYELOMA HYPERPLOID UP | |
| MOREAUX MULTIPLE MYELOMA BY TACI DN | |
| OUELLET CULTURED OVARIAN CANCER INVASIVE VS LMP UP | |
| NCI FORMATION AND MATURATION OF MRNA TRANSCRIPT | |
| RHODES CANCER META SIGNATURE | |
| NCI RNA POLYMERASE II TRANSCRIPTION INITIATION AND PROMOTER CLEARANCE | |
| REACTOME TRANSCRIPTION | POLR2E, POLR2D, MAGOH, POLR2F, TAF10, POLR2H, POLR2B, SSRP1, NCBP2, CSTF1, MNAT1, POLR2J |
| NCI TAT MEDIATED HIV 1 ELONGATION ARREST AND RECOVERY | |
| NCI PAUSING AND RECOVERY OF HIV 1 ELONGATION | |
| NCI HIV 1 TRANSCRIPTION PRE INITIATION | |
| REACTOME HIV LIFE CYCLE | POLR2D, POLR2F, RAE1, NUP37, TCEB2, CCNH, TAF10, RAN, POLR2H, POLR2B, NUP133, BANF1, MNAT1, POLR2J |
| NCI TRANSCRIPTION OF THE HIV GENOME | |
| MOOTHA PGC | |