BICLUSTER_ID : UPREG-102
PATHOGENS /5/ : pseudomonas aeruginosa,yersinia enterocolitica,helicobacter pylori,ehrlichia chaffeensis,burkholderia pseudomallei
TARGETS /3/ : CCL20, JUN, CCL2
Gene SetLeading Edge Genes
NETPATH IL 4 PATHWAY DOWNCCL20, CCL2, CXCL2
NETPATH IL 7 PATHWAY UPCXCL1, JUN, CXCL2
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
NOJIMA SFRP2 TARGETS UP
MISSIAGLIA REGULATED BY METHYLATION UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
SMIRNOV CIRCULATING ENDOTHELIOCYTES IN CANCER UP
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
MAHAJAN RESPONSE TO IL1A UP
CHUANG OXIDATIVE STRESS RESPONSE UP
AUJLA IL22 AND IL17A SIGNALING
DORN ADENOVIRUS INFECTION 32HR DN
REACTOME PEPTIDE LIGAND BINDING RECEPTORS
CROONQUIST STROMAL STIMULATION UP
SA MMP CYTOKINE CONNECTION
RASHI RESPONSE TO IONIZING RADIATION 2
LINDSTEDT DENDRITIC CELL MATURATION A
LIEN BREAST CARCINOMA METAPLASTIC VS DUCTAL UP
SAGIV CD24 TARGETS DN
ELVIDGE HYPOXIA UP
HORIUCHI WTAP TARGETS UP
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
AMIT EGF RESPONSE 40 HELA
ZHONG RESPONSE TO AZACITIDINE AND TSA UP
MAHADEVAN RESPONSE TO MP470 DN
JEON SMAD6 TARGETS UP
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
HARRIS HYPOXIA
HINATA NFKB TARGETS KERATINOCYTE UP
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 10D DN
SOUCEK MYC TARGETS
NAGASHIMA NRG1 SIGNALING UP
DUTTA APOPTOSIS VIA NFKB
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 6HR DN
ZERBINI RESPONSE TO SULINDAC UP
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS MAGENTA UP
CROMER TUMORIGENESIS UP
SABATES COLORECTAL ADENOMA UP
DIRMEIER LMP1 RESPONSE EARLY
MAHADEVAN RESPONSE TO MP470 UP
FERRARI RESPONSE TO FENRETINIDE UP
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
BILD HRAS ONCOGENIC SIGNATURE
ZHOU INFLAMMATORY RESPONSE LIVE UP
ONDER CDH1 TARGETS 3 DN
AMIT EGF RESPONSE 120 HELA
DAUER STAT3 TARGETS UP
HELLEBREKERS SILENCED DURING TUMOR ANGIOGENESIS
LIAN LIPA TARGETS 6M
PODAR RESPONSE TO ADAPHOSTIN UP
AMIT EGF RESPONSE 60 HELA
ADDYA ERYTHROID DIFFERENTIATION BY HEMIN
BERENJENO TRANSFORMED BY RHOA FOREVER DN
CHEN HOXA5 TARGETS 9HR UP
DAZARD UV RESPONSE CLUSTER G2
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS TURQUOISE UP
SEKI INFLAMMATORY RESPONSE LPS UP
AMIT SERUM RESPONSE 40 MCF10A
GRAHAM CML QUIESCENT VS CML DIVIDING UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
SATO SILENCED BY DEACETYLATION IN PANCREATIC CANCER
CONCANNON APOPTOSIS BY EPOXOMICIN UP
BROWNE HCMV INFECTION 4HR UP
GESERICK TERT TARGETS DN
SENESE HDAC1 AND HDAC2 TARGETS UP
BROWNE HCMV INFECTION 2HR UP
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
SESTO RESPONSE TO UV C3
KIM WT1 TARGETS UP
VERHAAK AML WITH NPM1 MUTATED UP
LIAN LIPA TARGETS 3M
GEISS RESPONSE TO DSRNA UP
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
GERY CEBP TARGETSATF3, CXCL1, GADD45G, PTX3
ZHOU INFLAMMATORY RESPONSE FIMA UP
HESS TARGETS OF HOXA9 AND MEIS1 DN
DASU IL6 SIGNALING UP
ELVIDGE HYPOXIA BY DMOG UP
CHASSOT SKIN WOUND
AMIT EGF RESPONSE 120 MCF10A
TIAN TNF SIGNALING VIA NFKB
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
NAGASHIMA EGF SIGNALING UP
AMIT DELAYED EARLY GENES
PRAMOONJAGO SOX4 TARGETS UP
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
KIM WT1 TARGETS 8HR UP
HINATA NFKB TARGETS FIBROBLAST UP
AMIT EGF RESPONSE 60 MCF10A
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
yersinia enterocolitica wap bcburkholderia pseudomalleiyersinia enterocolitica p60 bl6yersinia enterocolitica p60 bcehrlichia chaffeensis wakullapseudomonas aeruginosahelicobacter pylori kx2 mgepGeneSet Name
0.00024 0.16712 0.00146 0.00040 0.00000 0.00000 0.00009NETPATH_IL_4_PATHWAY_DOWN
0.00052 0.16021 0.00709 0.00028 0.00004 0.00151 0.00019NETPATH_IL_7_PATHWAY_UP
0.00001 0.02392 0.00000 0.00000 0.00000 0.00066 0.00022KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.00224 0.00000 0.00037 0.00304 0.00340 0.06631 0.00000NOJIMA_SFRP2_TARGETS_UP
0.00107 0.00964 0.00038 0.00145 0.00006 0.00002 0.00396MISSIAGLIA_REGULATED_BY_METHYLATION_UP
0.00000 0.01050 0.00000 0.00000 0.00301 0.00003 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.00133 0.13459 0.02220 0.00508 0.00000 0.02594 0.06739SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP
0.00000 0.00002 0.00021 0.00000 0.00547 0.01558 0.00541GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00000 0.01913 0.00010 0.00009 0.00447 0.00000 0.00001MAHAJAN_RESPONSE_TO_IL1A_UP
0.05875 0.05013 0.05687 0.11943 0.12450 0.17995 0.00171CHUANG_OXIDATIVE_STRESS_RESPONSE_UP
0.01777 0.14966 0.00953 0.00824 0.01045 0.04032 0.01624AUJLA_IL22_AND_IL17A_SIGNALING
0.01879 0.19819 0.00369 0.00471 0.17242 0.00267 0.00009DORN_ADENOVIRUS_INFECTION_32HR_DN
0.00741 0.05958 0.00054 0.00005 0.00014 0.00095 0.06781REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
0.00829 0.02367 0.00954 0.01017 0.00000 0.01456 0.05041CROONQUIST_STROMAL_STIMULATION_UP
0.00860 0.13793 0.01474 0.00023 0.00000 0.04053 0.11687SA_MMP_CYTOKINE_CONNECTION
0.00001 0.16626 0.00297 0.00008 0.00001 0.00000 0.00000RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.00000 0.00750 0.00029 0.00000 0.00000 0.00387 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.01065 0.09910 0.00543 0.00171 0.02903 0.02390 0.02379LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP
0.02459 0.00252 0.18844 0.07586 0.00451 0.00003 0.00458SAGIV_CD24_TARGETS_DN
0.00006 0.02727 0.00031 0.00036 0.00027 0.10177 0.00095ELVIDGE_HYPOXIA_UP
0.00023 0.03425 0.01137 0.00038 0.00059 0.10214 0.01380HORIUCHI_WTAP_TARGETS_UP
0.06007 0.09871 0.00563 0.00492 0.01247 0.00802 0.01339IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.00018 0.00290 0.00021 0.00031 0.00042 0.00000 0.00053AMIT_EGF_RESPONSE_40_HELA
0.03095 0.10875 0.07122 0.09717 0.00376 0.19524 0.09966ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP
0.00006 0.00025 0.00072 0.00009 0.08720 0.00187 0.00005MAHADEVAN_RESPONSE_TO_MP470_DN
0.07031 0.01183 0.01900 0.03022 0.00032 0.00094 0.00000JEON_SMAD6_TARGETS_UP
0.00000 0.12979 0.00184 0.00000 0.00174 0.00381 0.00010THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.00004 0.16949 0.00029 0.00029 0.00025 0.00391 0.00009HARRIS_HYPOXIA
0.00000 0.00143 0.00000 0.00000 0.00001 0.00000 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00004 0.01777 0.00040 0.00020 0.00000 0.09083 0.18617TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN
0.00001 0.03675 0.00018 0.00008 0.00027 0.00251 0.00002SOUCEK_MYC_TARGETS
0.00000 0.00002 0.00000 0.00000 0.00000 0.00113 0.00000NAGASHIMA_NRG1_SIGNALING_UP
0.00003 0.07914 0.00201 0.00013 0.00000 0.00086 0.00000DUTTA_APOPTOSIS_VIA_NFKB
0.00000 0.05436 0.00000 0.00004 0.01086 0.00023 0.01992TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN
0.16203 0.11717 0.05840 0.12784 0.11589 0.08983 0.00100ZERBINI_RESPONSE_TO_SULINDAC_UP
0.00313 0.00142 0.10560 0.01191 0.04386 0.00182 0.04284GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP
0.01752 0.04511 0.00030 0.00013 0.08461 0.00771 0.10547CROMER_TUMORIGENESIS_UP
0.02588 0.04328 0.00162 0.02321 0.03083 0.00094 0.05261SABATES_COLORECTAL_ADENOMA_UP
0.00000 0.04849 0.00018 0.00000 0.00000 0.00000 0.00124DIRMEIER_LMP1_RESPONSE_EARLY
0.00006 0.14983 0.00018 0.00000 0.00001 0.00009 0.00001MAHADEVAN_RESPONSE_TO_MP470_UP
0.00007 0.05896 0.01472 0.00050 0.00156 0.00003 0.00002FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.00000 0.10469 0.00012 0.00000 0.00000 0.00003 0.00000REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
0.00000 0.01123 0.00000 0.00000 0.00024 0.00110 0.00132BILD_HRAS_ONCOGENIC_SIGNATURE
0.00000 0.00909 0.00000 0.00000 0.00039 0.00000 0.00000ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.01083 0.05647 0.00026 0.00099 0.00507 0.00003 0.00020ONDER_CDH1_TARGETS_3_DN
0.00000 0.00027 0.00029 0.00004 0.00037 0.00184 0.00007AMIT_EGF_RESPONSE_120_HELA
0.06147 0.00256 0.06189 0.02597 0.00307 0.00006 0.00008DAUER_STAT3_TARGETS_UP
0.00401 0.09145 0.02280 0.00048 0.06671 0.00610 0.11815HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS
0.00074 0.04822 0.00177 0.02049 0.00000 0.14139 0.11920LIAN_LIPA_TARGETS_6M
0.00000 0.00000 0.00000 0.00001 0.00028 0.13378 0.00000PODAR_RESPONSE_TO_ADAPHOSTIN_UP
0.00000 0.02574 0.00019 0.00028 0.00102 0.17983 0.00000AMIT_EGF_RESPONSE_60_HELA
0.00197 0.17112 0.08832 0.06783 0.03269 0.02053 0.00073ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN
0.00000 0.00758 0.00332 0.00060 0.00358 0.00379 0.02345BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN
0.00001 0.03571 0.00807 0.00074 0.00291 0.00776 0.00000CHEN_HOXA5_TARGETS_9HR_UP
0.00772 0.02586 0.01250 0.01385 0.00111 0.01158 0.00000DAZARD_UV_RESPONSE_CLUSTER_G2
0.00000 0.00017 0.00056 0.00001 0.13273 0.07679 0.00092GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP
0.00000 0.01261 0.00000 0.00000 0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.06818 0.00000 0.00004 0.00005 0.00028 0.00219AMIT_SERUM_RESPONSE_40_MCF10A
0.00008 0.00000 0.00398 0.00030 0.00003 0.00000 0.00677GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00000 0.00139 0.00000 0.00000 0.00000 0.00000 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.03490 0.00209 0.00980 0.11465 0.04099 0.01071 0.15948SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER
0.00014 0.00000 0.00489 0.00226 0.01806 0.00121 0.00000CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP
0.00028 0.02223 0.00019 0.00000 0.01785 0.06023 0.04014BROWNE_HCMV_INFECTION_4HR_UP
0.00000 0.00623 0.00000 0.00004 0.00032 0.00178 0.00002GESERICK_TERT_TARGETS_DN
0.00001 0.10073 0.01129 0.00026 0.01080 0.03137 0.00621SENESE_HDAC1_AND_HDAC2_TARGETS_UP
0.02213 0.05164 0.00222 0.00673 0.11885 0.00000 0.00890BROWNE_HCMV_INFECTION_2HR_UP
0.00000 0.00000 0.00030 0.00006 0.00004 0.00000 0.00008HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00406 0.00000 0.00078 0.00270 0.01412 0.00703 0.00018SESTO_RESPONSE_TO_UV_C3
0.00000 0.05021 0.00039 0.00000 0.00017 0.00318 0.00000KIM_WT1_TARGETS_UP
0.00000 0.13600 0.00000 0.00000 0.00000 0.00267 0.00145VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.00070 0.03580 0.00252 0.01896 0.00000 0.12753 0.00925LIAN_LIPA_TARGETS_3M
0.00000 0.11502 0.00109 0.00000 0.00022 0.00051 0.00000GEISS_RESPONSE_TO_DSRNA_UP
0.00000 0.00019 0.00000 0.00000 0.00336 0.00002 0.00000UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.00013 0.00015 0.00040 0.00510 0.00116 0.00843 0.00038GERY_CEBP_TARGETS
0.00001 0.00000 0.00000 0.00000 0.02576 0.00000 0.00011ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP
0.00000 0.08705 0.00006 0.00004 0.00000 0.15886 0.11528HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN
0.00001 0.03694 0.00177 0.00020 0.03956 0.00000 0.10056DASU_IL6_SIGNALING_UP
0.00045 0.03396 0.00028 0.00017 0.00131 0.03582 0.00024ELVIDGE_HYPOXIA_BY_DMOG_UP
0.00188 0.16088 0.07095 0.00892 0.04468 0.06576 0.00239CHASSOT_SKIN_WOUND
0.00001 0.05040 0.00086 0.00028 0.03134 0.00069 0.00229AMIT_EGF_RESPONSE_120_MCF10A
0.00000 0.00000 0.00016 0.00000 0.00000 0.00000 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.00000 0.00000 0.00037 0.00000 0.00009 0.00000 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00000 0.02880 0.00000 0.00000 0.00265 0.00003 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.00000 0.00000 0.00000 0.00000 0.00000 0.00102 0.00000NAGASHIMA_EGF_SIGNALING_UP
0.00156 0.00501 0.06744 0.04380 0.00462 0.04481 0.00009AMIT_DELAYED_EARLY_GENES
0.00024 0.01688 0.02844 0.00119 0.00099 0.00151 0.00000PRAMOONJAGO_SOX4_TARGETS_UP
0.00000 0.09787 0.00000 0.00000 0.00107 0.04258 0.00000PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.00153 0.00345 0.06776 0.01140 0.07001 0.06159 0.00689KIM_WT1_TARGETS_8HR_UP
0.00001 0.03538 0.00034 0.00008 0.00151 0.00000 0.00009HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.00000 0.00375 0.00000 0.00000 0.00070 0.00367 0.00000AMIT_EGF_RESPONSE_60_MCF10A