BICLUSTER_ID : UPREG-110
PATHOGENS /7/ : pseudomonas aeruginosa,brucella neotomae,escherichia coli,streptococcus pneumoniae,helicobacter pylori,mycobacterium tuberculosis,shigella dysenteriae
TARGETS /2/ : PTGS2, PLAUR
Gene SetLeading Edge Genes
GERY CEBP TARGETSATF3, GADD45B, EREG, JUNB, PLAUR
NETPATH IL 1 PATHWAY UPNFKBIA, BIRC3, PTGS2, INHBA, CXCL2
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
NETPATH IL 9 PATHWAY UP
MAHAJAN RESPONSE TO IL1A UP
DORN ADENOVIRUS INFECTION 32HR DN
SESTO RESPONSE TO UV C1
LINDSTEDT DENDRITIC CELL MATURATION B
CROONQUIST STROMAL STIMULATION UP
HALMOS CEBPA TARGETS UP
LINDSTEDT DENDRITIC CELL MATURATION A
SIMBULAN UV RESPONSE NORMAL UP
ELVIDGE HYPOXIA UP
BIOCARTA CDMAC PATHWAY
AMIT EGF RESPONSE 40 HELA
NETPATH IL 4 PATHWAY DOWN
NETPATH IL 7 PATHWAY UPCXCL2
DORN ADENOVIRUS INFECTION 12HR UP
MAHADEVAN RESPONSE TO MP470 DN
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
NETPATH KIT RECEPTOR PATHWAY UP
HARRIS HYPOXIA
LENAOUR DENDRITIC CELL MATURATION DN
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP
HINATA NFKB TARGETS KERATINOCYTE UP
DORN ADENOVIRUS INFECTION 48HR DN
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
BASSO CD40 SIGNALING UP
AMIT SERUM RESPONSE 60 MCF10A
MARZEC IL2 SIGNALING UP
SOUCEK MYC TARGETS
NAGASHIMA NRG1 SIGNALING UP
DUTTA APOPTOSIS VIA NFKB
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 6HR DN
COULOUARN TEMPORAL TGFB1 SIGNATURE UP
DIRMEIER LMP1 RESPONSE EARLY
MAHADEVAN RESPONSE TO MP470 UP
FERRARI RESPONSE TO FENRETINIDE UP
ZHOU INFLAMMATORY RESPONSE LIVE UP
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLUE UP
AMIT EGF RESPONSE 120 HELA
DAUER STAT3 TARGETS UP
LIANG SILENCED BY METHYLATION 2
NETPATH IL 3 PATHWAY UP
NETPATH IL 6 PATHWAY UPGADD45B, JUNB, BHLHB2
NIELSEN MALIGNAT FIBROUS HISTIOCYTOMA UP
DAZARD RESPONSE TO UV NHEK UP
MCLACHLAN DENTAL CARIES UP
MENSE HYPOXIA UP
SHAFFER IRF4 TARGETS IN PLASMA CELL VS MATURE B LYMPHOCYTE
DAZARD UV RESPONSE CLUSTER G2
CHEN HOXA5 TARGETS 9HR UP
NETPATH IL 5 PATHWAY UPBIRC3, NFKB2, IER3
NCI CD40 PATHWAY
TAVOR CEBPA TARGETS UP
FOSTER INFLAMMATORY RESPONSE LPS DN
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
GRAHAM CML QUIESCENT VS CML DIVIDING UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
SATO SILENCED BY DEACETYLATION IN PANCREATIC CANCER
ZHOU INFLAMMATORY RESPONSE LPS UP
AMIT SERUM RESPONSE 120 MCF10A
DORN ADENOVIRUS INFECTION 24HR DN
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
SESTO RESPONSE TO UV C3
KIM WT1 TARGETS UP
VERHAAK AML WITH NPM1 MUTATED UP
BROCKE APOPTOSIS REVERSED BY IL6
ONDER CDH1 TARGETS 1 DN
GEISS RESPONSE TO DSRNA UP
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
ST TUMOR NECROSIS FACTOR PATHWAY
ZHOU INFLAMMATORY RESPONSE FIMA UP
DASU IL6 SIGNALING UP
ELVIDGE HYPOXIA BY DMOG UP
TIAN TNF SIGNALING VIA NFKB
NETPATH IL 2 PATHWAY UP
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
LEE LIVER CANCER HEPATOBLAST
ZUCCHI METASTASIS DN
NAGASHIMA EGF SIGNALING UP
PRAMOONJAGO SOX4 TARGETS UP
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
AMIT EGF RESPONSE 60 MCF10A
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
pseudomonas aeruginosa fdr440mycobacterium tuberculosishelicobacter pylori kx2 mgepbrucella neotomaestreptococcus pneumoniae tigr4shigella dysenteriaeescherichia coliGeneSet Name
0.00131 0.00000 0.00038 0.18522 0.00001 0.00067 0.01389GERY_CEBP_TARGETS
0.00000 0.00602 0.00000 0.00114 0.00001 0.00030 0.00000NETPATH_IL_1_PATHWAY_UP
0.00010 0.00000 0.00000 0.00128 0.00000 0.00000 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.01700 0.00002 0.00541 0.03682 0.00058 0.00252 0.00000GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.04269 0.08229 0.00202 0.00066 0.05141 0.05058 0.00028NETPATH_IL_9_PATHWAY_UP
0.00044 0.00132 0.00001 0.16767 0.00006 0.00316 0.00000MAHAJAN_RESPONSE_TO_IL1A_UP
0.00021 0.00008 0.00009 0.06343 0.00000 0.00014 0.00003DORN_ADENOVIRUS_INFECTION_32HR_DN
0.00240 0.01198 0.00303 0.03217 0.00117 0.19068 0.00038SESTO_RESPONSE_TO_UV_C1
0.00000 0.00000 0.00000 0.02410 0.00796 0.00053 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00017 0.00025 0.05041 0.00132 0.00000 0.00808 0.00003CROONQUIST_STROMAL_STIMULATION_UP
0.00031 0.01212 0.03870 0.07569 0.00000 0.00005 0.00001HALMOS_CEBPA_TARGETS_UP
0.00003 0.00000 0.00000 0.00010 0.15403 0.00034 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.01311 0.04602 0.04290 0.01104 0.00048 0.03162 0.01024SIMBULAN_UV_RESPONSE_NORMAL_UP
0.16459 0.00052 0.00095 0.04424 0.00000 0.00124 0.01124ELVIDGE_HYPOXIA_UP
0.00516 0.12581 0.12419 0.12720 0.00114 0.00253 0.02242BIOCARTA_CDMAC_PATHWAY
0.15015 0.00000 0.00053 0.01260 0.00000 0.00000 0.00000AMIT_EGF_RESPONSE_40_HELA
0.00000 0.00000 0.00009 0.00269 0.01938 0.16501 0.00000NETPATH_IL_4_PATHWAY_DOWN
0.00003 0.00856 0.00019 0.01290 0.00009 0.04120 0.00000NETPATH_IL_7_PATHWAY_UP
0.04477 0.00008 0.00625 0.02401 0.00004 0.00527 0.04767DORN_ADENOVIRUS_INFECTION_12HR_UP
0.02760 0.00000 0.00005 0.00665 0.00000 0.00000 0.00317MAHADEVAN_RESPONSE_TO_MP470_DN
0.00052 0.00000 0.00010 0.01038 0.00077 0.00000 0.00000THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.18259 0.00019 0.00355 0.05217 0.00001 0.00112 0.00023NETPATH_KIT_RECEPTOR_PATHWAY_UP
0.00003 0.00067 0.00009 0.17495 0.00000 0.00501 0.00034HARRIS_HYPOXIA
0.10124 0.00000 0.11818 0.13798 0.02611 0.02446 0.02437LENAOUR_DENDRITIC_CELL_MATURATION_DN
0.00448 0.00000 0.00012 0.05608 0.00002 0.00000 0.00002DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP
0.00000 0.00000 0.00000 0.09086 0.00741 0.00078 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00037 0.00008 0.00009 0.11822 0.00001 0.00056 0.00089DORN_ADENOVIRUS_INFECTION_48HR_DN
0.00034 0.00060 0.00019 0.00378 0.02561 0.00096 0.00000KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00000 0.00000 0.01278 0.03927 0.01887 0.00004 0.00000BASSO_CD40_SIGNALING_UP
0.01060 0.00001 0.00000 0.11766 0.00000 0.00000 0.00109AMIT_SERUM_RESPONSE_60_MCF10A
0.01502 0.00127 0.01784 0.08610 0.01084 0.00321 0.00002MARZEC_IL2_SIGNALING_UP
0.02994 0.02521 0.00002 0.01093 0.02991 0.02047 0.00037SOUCEK_MYC_TARGETS
0.00002 0.00000 0.00000 0.06679 0.00000 0.00000 0.00000NAGASHIMA_NRG1_SIGNALING_UP
0.00513 0.00002 0.00000 0.00644 0.00090 0.02611 0.00000DUTTA_APOPTOSIS_VIA_NFKB
0.06809 0.00228 0.01992 0.01515 0.04093 0.11301 0.05842TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN
0.02348 0.02560 0.02721 0.11146 0.02113 0.14473 0.01809COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP
0.00002 0.00000 0.00124 0.00214 0.00000 0.00000 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.00002 0.00004 0.00001 0.09849 0.05724 0.06328 0.00000MAHADEVAN_RESPONSE_TO_MP470_UP
0.00002 0.00018 0.00002 0.02413 0.00024 0.00712 0.00016FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.00010 0.00002 0.00000 0.01309 0.00172 0.00006 0.00000ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.02769 0.00000 0.00044 0.01477 0.00000 0.00009 0.00155GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP
0.00068 0.00000 0.00007 0.02726 0.00000 0.00113 0.00046AMIT_EGF_RESPONSE_120_HELA
0.00085 0.00000 0.00008 0.00155 0.00000 0.00005 0.00003DAUER_STAT3_TARGETS_UP
0.00005 0.00000 0.00002 0.01035 0.13850 0.00396 0.00000LIANG_SILENCED_BY_METHYLATION_2
0.15088 0.00171 0.13629 0.00000 0.00810 0.00147 0.00000NETPATH_IL_3_PATHWAY_UP
0.03716 0.00000 0.01969 0.01660 0.00000 0.00000 0.00000NETPATH_IL_6_PATHWAY_UP
0.01078 0.02002 0.00622 0.19381 0.05863 0.13279 0.00438NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP
0.10778 0.00196 0.01957 0.11484 0.00000 0.00111 0.00002DAZARD_RESPONSE_TO_UV_NHEK_UP
0.00001 0.00000 0.00006 0.00479 0.18322 0.01598 0.00000MCLACHLAN_DENTAL_CARIES_UP
0.05632 0.00000 0.00036 0.06879 0.00000 0.02114 0.09188MENSE_HYPOXIA_UP
0.09246 0.00911 0.07351 0.13954 0.00114 0.03786 0.05575SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE
0.00228 0.01541 0.00000 0.00657 0.00000 0.00032 0.00004DAZARD_UV_RESPONSE_CLUSTER_G2
0.00550 0.00006 0.00000 0.02011 0.00003 0.00000 0.00050CHEN_HOXA5_TARGETS_9HR_UP
0.00726 0.00000 0.00002 0.12369 0.00002 0.00014 0.00001NETPATH_IL_5_PATHWAY_UP
0.00530 0.01575 0.00002 0.16739 0.11127 0.00073 0.00010NCI_CD40_PATHWAY
0.08516 0.00011 0.04908 0.11809 0.01378 0.00349 0.00020TAVOR_CEBPA_TARGETS_UP
0.00037 0.00000 0.00146 0.00621 0.01424 0.00236 0.00000FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.00000 0.00000 0.00000 0.00041 0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00002 0.00000 0.00000 0.00119 0.09452 0.04466 0.00000GAURNIER_PSMD4_TARGETS
0.00002 0.00000 0.00677 0.07552 0.00000 0.00003 0.00000GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00000 0.00000 0.00000 0.00387 0.00001 0.00000 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.01084 0.00117 0.15948 0.03432 0.00028 0.00666 0.00071SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER
0.00027 0.00000 0.00059 0.02297 0.05005 0.03754 0.00000ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.02960 0.00013 0.00109 0.11404 0.00000 0.00021 0.00011AMIT_SERUM_RESPONSE_120_MCF10A
0.00130 0.00000 0.00000 0.10827 0.00000 0.00042 0.00667DORN_ADENOVIRUS_INFECTION_24HR_DN
0.00011 0.00000 0.00008 0.00059 0.00000 0.00000 0.00000HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.02538 0.00000 0.00018 0.04591 0.00000 0.00000 0.00001SESTO_RESPONSE_TO_UV_C3
0.00002 0.00007 0.00000 0.10627 0.00001 0.00000 0.00002KIM_WT1_TARGETS_UP
0.00218 0.00000 0.00145 0.03242 0.01022 0.00095 0.00000VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.04896 0.00000 0.00158 0.11642 0.00015 0.00055 0.00002BROCKE_APOPTOSIS_REVERSED_BY_IL6
0.00709 0.07350 0.00512 0.17331 0.00114 0.09552 0.00021ONDER_CDH1_TARGETS_1_DN
0.00007 0.00000 0.00000 0.01183 0.03793 0.01687 0.00000GEISS_RESPONSE_TO_DSRNA_UP
0.02749 0.00000 0.00000 0.00256 0.00000 0.00000 0.00044UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.00001 0.00010 0.00008 0.09858 0.10060 0.01233 0.00026ST_TUMOR_NECROSIS_FACTOR_PATHWAY
0.00013 0.00047 0.00011 0.05928 0.02569 0.01029 0.00000ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP
0.00711 0.00006 0.10056 0.12777 0.00007 0.00099 0.00015DASU_IL6_SIGNALING_UP
0.15685 0.00043 0.00024 0.11243 0.00000 0.00078 0.01098ELVIDGE_HYPOXIA_BY_DMOG_UP
0.00000 0.00000 0.00000 0.05899 0.00001 0.00005 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.00843 0.00008 0.04909 0.17779 0.07061 0.08636 0.00000NETPATH_IL_2_PATHWAY_UP
0.00000 0.00002 0.00000 0.00010 0.00000 0.00000 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00011 0.00000 0.00000 0.00123 0.00000 0.00000 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.00243 0.13990 0.10358 0.17189 0.01752 0.00154 0.00010LEE_LIVER_CANCER_HEPATOBLAST
0.00002 0.00039 0.00076 0.01371 0.00000 0.00013 0.00000ZUCCHI_METASTASIS_DN
0.00002 0.00000 0.00000 0.01336 0.00000 0.00000 0.00003NAGASHIMA_EGF_SIGNALING_UP
0.00044 0.00000 0.00000 0.10655 0.00000 0.00000 0.00005PRAMOONJAGO_SOX4_TARGETS_UP
0.06556 0.00000 0.00000 0.16797 0.00000 0.00000 0.02690PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.00027 0.00004 0.00000 0.02489 0.00000 0.00000 0.00000AMIT_EGF_RESPONSE_60_MCF10A