BICLUSTER_ID : UPREG-112
PATHOGENS /2/ : bifidobacterium bifidum,streptococcus pneumoniae
TARGETS /23/ : ACPP, LCN2, SERPINB2, MTHFD2, AURKA, CDC25B, AMPD3, PIM1, TXNRD1, MAP2K1, CFB, NFKB1, STAT1, PSMB5, NP, WEE1, FYN, IL6, SERPINE1, PTGS2, PLOD2, CASP1, GRB2
Gene SetLeading Edge Genes
NETPATH IL 1 PATHWAY UPACPP, RHOB, LCN2, SERPINB2, FOSL1, MTHFD2, LOX, AMPD3, MT2A, UST, INHBA, CXCL2, TXNRD1, SOD2, CFB, NFKB1, BIRC3, LIF, CXCL1, PTTG1, NP, JMJD3, TNFAIP6, IL6, SERPINE1, PTGS2, ZFP36
NETPATH IL 6 PATHWAYNFKB1, SGK, SHC1, GAB1, STAT1, JAK1, IL6, FYN, FOXO1A, STAT3, GRB2, MAP2K1
NCI PLK1 PATHWAYFBXO5, BUB1B, KIF20A, CDC20, BUB1, MLF1IP, WEE1, CCNB1, AURKA, CDC25B, PRC1, PAK1, CENPE, ROCK2
NETPATH IL 2 PATHWAYETS2, NFKB1, SHC1, STAT1, FYN, STAT3, JAK1, NMI
NETPATH IL 6 PATHWAY UPSGK, STAT1, GADD45B, CXCL1, ABCC5, MAP3K8, CDKN1B, NMI, ZFP36, STAT3, PIM1, IRF1, PRDM1
NCI VIF MEDIATED DEGRADATION OF APOBEC3GPSMD5, PSMD7, UBC, PSMA5, TCEB1, PSMA2, PSMB6, PSMC1, PSME2, PSMA4, PSMD9, PSMB7, PSMD4, PSMA3, PSMF1, PSME1, RBX1, PSMA6, PSMB5, PSMD10, PSMD8, PSMC2, PSMC6
NCI UBIQUITIN MEDIATED DEGRADATION OF PHOSPHORYLATED CDC25APSMD5, PSMD7, UBC, PSMA5, PSMA2, PSMB6, PSMC1, PSME2, PSMA4, PSMD9, PSMB7, PSMD4, PSMA3, PSMF1, PSME1, PSMA6, PSMB5, PSMD10, PSMD8, PSMC2, PSMC6
NETPATH IL 1 PATHWAYSQSTM1, IL1RN, CASP1
NCI SCF BETA TRCP MEDIATED DEGRADATION OF EMI1PSMD5, PSMD7, UBC, PSMA5, PSMA2, PSMB6, PSMC1, PSME2, PSMA4, PSMD9, PSMB7, PSMD4, BTRC, PSMA3, PSMF1, PSME1, PSMA6, PSMB5, PSMD10, PSMD8, PSMC2, PSMC6
NCI REGULATION OF ACTIVATED PAK 2P34 BY PROTEASOME MEDIATED DEGRADATION1PSMD5, PSMD7, UBC, PSMA5, PSMA2, PSMB6, PSMC1, PSME2, PSMA4, PSMD9, PSMB7, PSMD4, PSMA3, PSMF1, PSME1, PSMA6, PSMB5, PSMD10, PSMD8, PSMC2, PSMC6
MENSE HYPOXIA UPMXI1, PFKFB3, HK2, CDC2L6, TSLP, PPP1R3C, GADD45A, JMJD1A, LOX, PEX13, PTDSR, SLC6A6, FOXD1, TIPARP, NDRG1, VEGF, NFIL3, ENO2, ATF3, PLOD2, ANKRD37
NCI REGULATION OF ACTIVATED PAK 2P34 BY PROTEASOME MEDIATED DEGRADATIONPSMD5, PSMD7, UBC, PSMA5, PSMA2, PSMB6, PSMC1, PSME2, PSMA4, PSMD9, PSMB7, PSMD4, PSMA3, PSMF1, PSME1, PSMA6, PSMB5, PSMD10, PSMD8, PSMC2, PSMC6
WEINMANN ADAPTATION TO HYPOXIA UP
NCI BCR 5PATHWAY
REACTOME SIGNALING BY PDGF
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
PUJANA BRCA1 PCC NETWORK
MAHAJAN RESPONSE TO IL1A UP
PUJANA BRCA2 PCC NETWORK
WEINMANN ADAPTATION TO HYPOXIA DN
BIOCARTA IL6 PATHWAY
CHUANG OXIDATIVE STRESS RESPONSE UP
VARELA ZMPSTE24 TARGETS UP
NCI TNFPATHWAY
LINDSTEDT DENDRITIC CELL MATURATION B
NCI HOST INTERACTIONS OF HIV FACTORS
RASHI RESPONSE TO IONIZING RADIATION 2
HUANG FOXA2 TARGETS DN
NUYTTEN EZH2 TARGETS DN
LIEN BREAST CARCINOMA METAPLASTIC VS DUCTAL UP
SESTO RESPONSE TO UV C0
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
AMIT EGF RESPONSE 40 HELA
NETPATH IL 7 PATHWAY UP
NAKAYAMA FRA2 TARGETS
MITSIADES RESPONSE TO APLIDIN UP
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
NCI DISSOLUTION OF FIBRIN CLOT
TRAYNOR RETT SYNDROM UP
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION ERYTHROCYTE UP
MARTORIATI MDM4 TARGETS FETAL LIVER UP
BOYAULT LIVER CANCER SUBCLASS G56 DN
HINATA NFKB TARGETS KERATINOCYTE UP
RUTELLA RESPONSE TO CSF2RB AND IL4 UP
DOUGLAS BMI1 TARGETS DN
TIEN INTESTINE PROBIOTICS 24HR UP
CORUM CD20-LCK-LYN-FYN-P75/80 COMPLEX RAJI HUMAN B CELL LINE
KOKKINAKIS METHIONINE DEPRIVATION 96HR UP
MARKEY RB1 ACUTE LOF UP
NCI HIF1 TFPATHWAY
AMIT SERUM RESPONSE 60 MCF10A
COULOUARN TEMPORAL TGFB1 SIGNATURE UP
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS MAGENTA UP
HAN SATB1 TARGETS DN
BIOCARTA CD40 PATHWAY
SHIPP DLBCL VS FOLLICULAR LYMPHOMA UP
KEGG ETHER LIPID METABOLISM
RUTELLA RESPONSE TO HGF VS CSF2RB AND IL4 DN
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLUE UP
AMIT EGF RESPONSE 120 HELA
DEBOSSCHER NFKB TARGETS REPRESSED BY GLUCOCORTICOIDS
BIOCARTA RANKL PATHWAY
DANG REGULATED BY MYC DN
KYNG DNA DAMAGE BY UV
PODAR RESPONSE TO ADAPHOSTIN UP
SHAFFER IRF4 TARGETS IN PLASMA CELL VS MATURE B LYMPHOCYTE
KYNG DNA DAMAGE UP
LEE LIVER CANCER E2F1 UP
HELLER SILENCED BY METHYLATION UP
KERLEY RESPONSE TO CISPLATIN UP
GOZGIT ESR1 TARGETS DN
RHEIN ALL GLUCOCORTICOID THERAPY DN
BERENJENO TRANSFORMED BY RHOA UP
CORUM REL-MAP3K8-RELA-TNIP2-PAPOLA COMPLEX
CORUM PA700-20S-PA28 COMPLEX
VERHAAK AML WITH NPM1 MUTATED UP
BROCKE APOPTOSIS REVERSED BY IL6
GERY CEBP TARGETS
REACTOME SNRNP ASSEMBLY
FOURNIER ACINAR DEVELOPMENT LATE 2
ST TUMOR NECROSIS FACTOR PATHWAY
CORUM SPLICEOSOME
TIAN TNF SIGNALING VIA NFKB
ZHANG PROLIFERATING VS QUIESCENT
HUMMEL BURKITTS LYMPHOMA DN
KEGG APOPTOSIS
NCI DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX
SCHLOSSER MYC TARGETS AND SERUM RESPONSE DN
DODD NASOPHARYNGEAL CARCINOMA DN
CHIANG LIVER CANCER SUBCLASS CTNNB1 DN
HINATA NFKB TARGETS FIBROBLAST UP
CHARAFE BREAST CANCER LUMINAL VS BASAL DN
NAKAMURA TUMOR ZONE PERIPHERAL VS CENTRAL DN
MISSIAGLIA REGULATED BY METHYLATION UP
NCI ATF2 PATHWAY
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX CHUK BTRC NFKB2 PPP6C REL CUL1 IKBKE SAPS2 SAPS1 ANKRD28 RELA SKP1
GEORGANTAS HSC MARKERS
MITSIADES RESPONSE TO APLIDIN DN
TARTE PLASMA CELL VS PLASMABLAST DN
CROONQUIST STROMAL STIMULATION UP
KHETCHOUMIAN TRIM24 TARGETS UP
SEMBA FHIT TARGETS UP
HORIUCHI WTAP TARGETS UP
CORUM PA28-20S PROTEASOME
ZHANG ANTIVIRAL RESPONSE TO RIBAVIRIN UP
RUTELLA RESPONSE TO CSF2RB AND IL4 DN
CHIARADONNA NEOPLASTIC TRANSFORMATION KRAS CDC25 DN
CLASPER LYMPHATIC VESSELS DURING METASTASIS DN
TURASHVILI BREAST DUCTAL CARCINOMA VS DUCTAL NORMAL DN
SCHAVOLT TARGETS OF TP53 AND TP63
MORI PRE BI LYMPHOCYTE DN
DER IFN BETA RESPONSE UP
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP
DIRMEIER LMP1 RESPONSE LATE UP
CAIRO HEPATOBLASTOMA CLASSES UP
GALI TP53 TARGETS APOPTOTIC UP
BASSO CD40 SIGNALING UP
TIAN TNF SIGNALING NOT VIA NFKB
NAGASHIMA NRG1 SIGNALING UP
MARZEC IL2 SIGNALING UP
ZERBINI RESPONSE TO SULINDAC UP
CROMER TUMORIGENESIS UP
FRIDMAN SENESCENCE UP
FERRARI RESPONSE TO FENRETINIDE UP
SEITZ NEOPLASTIC TRANSFORMATION BY 8P DELETION DN
CHEMNITZ RESPONSE TO PROSTAGLANDIN E2 UP
PUJANA XPRSS INT NETWORK
SANA RESPONSE TO IFNG UP
BENPORATH CYCLING GENES
REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G
ZHANG ANTIVIRAL RESPONSE TO RIBAVIRIN DN
ELVIDGE HIF1A AND HIF2A TARGETS DN
WU HBX TARGETS 1 UP
KYNG ENVIRONMENTAL STRESS RESPONSE NOT BY 4NQO IN OLD
REACTOME BOTULINUM NEUROTOXICITY
KANNAN TP53 TARGETS UP
CHEN HOXA5 TARGETS 9HR UP
NETPATH IL 5 PATHWAY UP
SEKI INFLAMMATORY RESPONSE LPS UP
DAZARD UV RESPONSE CLUSTER G24
GRAHAM CML QUIESCENT VS CML DIVIDING UP
CONCANNON APOPTOSIS BY EPOXOMICIN UP
MURAKAMI UV RESPONSE 6HR UP
BUYTAERT PHOTODYNAMIC THERAPY STRESS UP
WANG METHYLATED IN BREAST CANCER
LIU TARGETS OF VMYB VS CMYB DN
ODONNELL TARGETS OF MYC AND TFRC UP
KYNG ENVIRONMENTAL STRESS RESPONSE NOT BY GAMMA IN WS
BIOCARTA IL7 PATHWAY
CHIANG LIVER CANCER SUBCLASS PROLIFERATION UP
STREICHER LSM1 TARGETS UP
LINDSTEDT DENDRITIC CELL MATURATION C
HESS TARGETS OF HOXA9 AND MEIS1 DN
ELVIDGE HYPOXIA BY DMOG UP
WONG EMBRYONIC STEM CELL CORE
VANTVEER BREAST CANCER METASTASIS DN
BIOCARTA IL2RB PATHWAY
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
PUJANA BREAST CANCER WITH BRCA1 MUTATED UP
BERTUCCI MEDULLARY VS DUCTAL BREAST CANCER UP
RUTELLA RESPONSE TO HGF UP
HOSHIDA LIVER CANCER LATE RECURRENCE UP
PRAMOONJAGO SOX4 TARGETS UP
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 1
ELVIDGE HIF1A TARGETS DN
SCHLOSSER MYC TARGETS AND SERUM RESPONSE UP
LI WILMS TUMOR VS FETAL KIDNEY 1 DN
PAL PRMT5 TARGETS UP
LINDSTEDT DENDRITIC CELL MATURATION A
RUGO UV RESPONSE
ELVIDGE HYPOXIA UP
BIOCARTA BIOPEPTIDES PATHWAY
BROWNE INTERFERON RESPONSIVE GENES
CASORELLI ACUTE PROMYELOCYTIC LEUKEMIA DN
NCI IL6 7PATHWAY
RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED UP
KRIGE RESPONSE TO TOSEDOSTAT 24HR DN
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION SUSTAINDED IN ERYTHROCYTE UP
NUYTTEN NIPP1 TARGETS UP
ST TYPE I INTERFERON PATHWAY
FRIDMAN IMMORTALIZATION DN
PUJANA CHEK2 PCC NETWORK
AKL HTLV1 INFECTION DN
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
PYEON HPV POSITIVE TUMORS UP
NUYTTEN EZH2 TARGETS UP
DUTTA APOPTOSIS VIA NFKB
KRISHNAN FURIN TARGETS UP
DIRMEIER LMP1 RESPONSE EARLY
NCI VPU MEDIATED DEGRADATION OF CD4
KYNG ENVIRONMENTAL STRESS RESPONSE UP
LINDGREN BLADDER CANCER CLUSTER 3 UP
ZHOU INFLAMMATORY RESPONSE LIVE UP
ONDER CDH1 TARGETS 3 DN
RUTELLA RESPONSE TO HGF VS CSF2RB AND IL4 UP
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS RED UP
NIELSEN MALIGNAT FIBROUS HISTIOCYTOMA UP
WINTER HYPOXIA METAGENE
NCI SNRNP ASSEMBLY
NEWMAN ERCC6 TARGETS UP
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS TURQUOISE UP
FOSTER INFLAMMATORY RESPONSE LPS DN
REACTOME P53 INDEPENDENT DNA DAMAGE RESPONSE
SATO SILENCED BY DEACETYLATION IN PANCREATIC CANCER
ZHANG BREAST CANCER PROGENITORS UP
BLUM RESPONSE TO SALIRASIB DN
NETPATH TNF ALPHA PATHWAY UP
VETTER TARGETS OF PRKCA AND ETS1 DN
GESERICK TERT TARGETS DN
AMIT SERUM RESPONSE 120 MCF10A
REACTOME REGULATION OF ORNITHINE DECARBOXYLASE
NCI IL1PATHWAY
SESTO RESPONSE TO UV C3
BIOCARTA PDGF PATHWAY
GEISS RESPONSE TO DSRNA UP
BIOCARTA EGF PATHWAY
GRAHAM CML DIVIDING VS NORMAL QUIESCENT DN
WEI MYCN TARGETS WITH E BOX
BIOCARTA TPO PATHWAY
GRUETZMANN PANCREATIC CANCER UP
VECCHI GASTRIC CANCER EARLY UP
KEGG PROTEASOME
OKUMURA INFLAMMATORY RESPONSE LPS
LEE LIVER CANCER HEPATOBLAST
NAGASHIMA EGF SIGNALING UP
AMIT DELAYED EARLY GENES
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 17
BENPORATH PROLIFERATION
AMIT EGF RESPONSE 60 MCF10A
NOJIMA SFRP2 TARGETS UP
NAKAYAMA SOFT TISSUE TUMORS PCA2 UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
SMIRNOV CIRCULATING ENDOTHELIOCYTES IN CANCER UP
KRIGE RESPONSE TO TOSEDOSTAT 6HR DN
NETPATH EGFR1 PATHWAY DOWN
LEONARD HYPOXIA
BERENJENO TRANSFORMED BY RHOA REVERSIBLY UP
REACTOME CTLA4 INHIBITORY SIGNALING
NCI NFKAPPABATYPICALPATHWAY
BUYTAERT PHOTODYNAMIC THERAPY STRESS DN
LEE LIVER CANCER DENA UP
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 9
NETPATH IL 7 PATHWAY
ONDER CDH1 SIGNALING VIA CTNNB1
GUTIERREZ WALDENSTROEMS MACROGLOBULINEMIA 1 DN
ZHONG RESPONSE TO AZACITIDINE AND TSA UP
MAHADEVAN RESPONSE TO MP470 DN
RIGGINS TAMOXIFEN RESISTANCE DN
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 3D UP
HARRIS HYPOXIA
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS DN
KOKKINAKIS METHIONINE DEPRIVATION 48HR UP
RUGO ENVIRONMENTAL STRESS RESPONSE UP
REACTOME METABOLISM OF RNA
SOUCEK MYC TARGETS
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS LIGHTYELLOW UP
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 6
IZADPANAH STEM CELL ADIPOSE VS BONE UP
ZHAN MULTIPLE MYELOMA LB DN
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION HSC UP
GOLDRATH ANTIGEN RESPONSE
SHAFFER IRF4 MULTIPLE MYELOMA PROGRAM
BILD HRAS ONCOGENIC SIGNATURE
LIANG SILENCED BY METHYLATION 2
DAUER STAT3 TARGETS UP
DER IFN ALPHA RESPONSE UP
LEE LIVER CANCER ACOX1 UP
PELLICCIOTTA HDAC IN ANTIGEN PRESENTATION DN
DAZARD UV RESPONSE CLUSTER G2
AMUNDSON DNA DAMAGE RESPONSE TP53
WINNEPENNINCKX MELANOMA METASTASIS UP
SCHUHMACHER MYC TARGETS UP
AMIT SERUM RESPONSE 40 MCF10A
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
GAUSSMANN MLL AF4 FUSION TARGETS F UP
HELLER SILENCED BY METHYLATION DN
BIERIE INFLAMMATORY RESPONSE TGFB1
SANA TNF SIGNALING UP
SENESE HDAC1 AND HDAC2 TARGETS UP
ONDER CDH1 TARGETS 2 DN
AMIT EGF RESPONSE 240 HELA
REACTOME STABILIZATION OF P53
NCI REGULATION OF ORNITHINE DECARBOXYLASE ODC
MAINA VHL TARGETS DN
BIDUS METASTASIS UP
CASTELLANO NRAS TARGETS UP
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
JISON SICKLE CELL DISEASE UP
KINSEY TARGETS OF EWSR1 FLII FUSION UP
NCI NFKAPPABCANONICALPATHWAY
KEGG CELL CYCLE
XU HGF SIGNALING NOT VIA AKT1 48HR UP
DASU IL6 SIGNALING UP
FARMER BREAST CANCER CLUSTER 2
NETPATH IL 2 PATHWAY UP
HUPER BREAST BASAL VS LUMINAL UP
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
NCI PDGFRBPATHWAY
ZUCCHI METASTASIS DN
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
streptococcus pneumoniae g54bifidobacterium bifidumGeneSet Name
0.02186 0.00007NETPATH_IL_1_PATHWAY_UP
0.03948 0.11299NETPATH_IL_6_PATHWAY
0.04375 0.00000NCI_PLK1_PATHWAY
0.04610 0.08923NETPATH_IL_2_PATHWAY
0.01842 0.00007NETPATH_IL_6_PATHWAY_UP
0.03365 0.07191NCI_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G
0.04458 0.04750NCI_UBIQUITIN_MEDIATED_DEGRADATION_OF_PHOSPHORYLATED_CDC25A
0.03624 0.03028NETPATH_IL_1_PATHWAY
0.03767 0.04677NCI_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1
0.04333 0.06494NCI_REGULATION_OF_ACTIVATED_PAK_2P34_BY_PROTEASOME_MEDIATED_DEGRADATION1
0.00004 0.13132MENSE_HYPOXIA_UP
0.04796 0.04561NCI_REGULATION_OF_ACTIVATED_PAK_2P34_BY_PROTEASOME_MEDIATED_DEGRADATION
0.11807 0.11428WEINMANN_ADAPTATION_TO_HYPOXIA_UP
0.05244 0.19352NCI_BCR_5PATHWAY
0.04703 0.09326REACTOME_SIGNALING_BY_PDGF
0.03257 0.00214GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.10985 0.00000PUJANA_BRCA1_PCC_NETWORK
0.08911 0.00474MAHAJAN_RESPONSE_TO_IL1A_UP
0.10181 0.00000PUJANA_BRCA2_PCC_NETWORK
0.00875 0.01898WEINMANN_ADAPTATION_TO_HYPOXIA_DN
0.06093 0.15558BIOCARTA_IL6_PATHWAY
0.12323 0.00390CHUANG_OXIDATIVE_STRESS_RESPONSE_UP
0.01900 0.07949VARELA_ZMPSTE24_TARGETS_UP
0.16078 0.00099NCI_TNFPATHWAY
0.00817 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.04816 0.04307NCI_HOST_INTERACTIONS_OF_HIV_FACTORS
0.00271 0.00098RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.10801 0.15063HUANG_FOXA2_TARGETS_DN
0.05540 0.00000NUYTTEN_EZH2_TARGETS_DN
0.04813 0.06739LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP
0.00808 0.14665SESTO_RESPONSE_TO_UV_C0
0.03272 0.01539IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.02615 0.00190AMIT_EGF_RESPONSE_40_HELA
0.11486 0.01764NETPATH_IL_7_PATHWAY_UP
0.14370 0.11957NAKAYAMA_FRA2_TARGETS
0.00669 0.13478MITSIADES_RESPONSE_TO_APLIDIN_UP
0.09013 0.07330THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.12100 0.17948NCI_DISSOLUTION_OF_FIBRIN_CLOT
0.04692 0.07547TRAYNOR_RETT_SYNDROM_UP
0.13995 0.00139TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP
0.07515 0.17120MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP
0.12091 0.16391BOYAULT_LIVER_CANCER_SUBCLASS_G56_DN
0.00568 0.00013HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00276 0.10892RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP
0.04096 0.19744DOUGLAS_BMI1_TARGETS_DN
0.00438 0.00000TIEN_INTESTINE_PROBIOTICS_24HR_UP
0.11106 0.12054CORUM_CD20-LCK-LYN-FYN-P75/80_COMPLEX_RAJI_HUMAN_B_CELL_LINE
0.02436 0.06502KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP
0.10730 0.00000MARKEY_RB1_ACUTE_LOF_UP
0.10049 0.18004NCI_HIF1_TFPATHWAY
0.00321 0.15969AMIT_SERUM_RESPONSE_60_MCF10A
0.00641 0.02296COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP
0.00558 0.00919GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP
0.04828 0.13458HAN_SATB1_TARGETS_DN
0.09309 0.00439BIOCARTA_CD40_PATHWAY
0.16929 0.00000SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_UP
0.14173 0.18648KEGG_ETHER_LIPID_METABOLISM
0.00340 0.17262RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN
0.01216 0.00015GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP
0.01466 0.00402AMIT_EGF_RESPONSE_120_HELA
0.15437 0.06366DEBOSSCHER_NFKB_TARGETS_REPRESSED_BY_GLUCOCORTICOIDS
0.11238 0.00140BIOCARTA_RANKL_PATHWAY
0.07999 0.10901DANG_REGULATED_BY_MYC_DN
0.10260 0.06414KYNG_DNA_DAMAGE_BY_UV
0.00016 0.00133PODAR_RESPONSE_TO_ADAPHOSTIN_UP
0.03041 0.06171SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE
0.00926 0.14393KYNG_DNA_DAMAGE_UP
0.05639 0.00724LEE_LIVER_CANCER_E2F1_UP
0.17361 0.02743HELLER_SILENCED_BY_METHYLATION_UP
0.01965 0.03252KERLEY_RESPONSE_TO_CISPLATIN_UP
0.03000 0.14873GOZGIT_ESR1_TARGETS_DN
0.01120 0.00000RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN
0.09492 0.00000BERENJENO_TRANSFORMED_BY_RHOA_UP
0.08343 0.02230CORUM_REL-MAP3K8-RELA-TNIP2-PAPOLA_COMPLEX
0.04807 0.17202CORUM_PA700-20S-PA28_COMPLEX
0.12533 0.02011VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.09635 0.02793BROCKE_APOPTOSIS_REVERSED_BY_IL6
0.12493 0.00008GERY_CEBP_TARGETS
0.05639 0.00000REACTOME_SNRNP_ASSEMBLY
0.02894 0.00000FOURNIER_ACINAR_DEVELOPMENT_LATE_2
0.10551 0.00028ST_TUMOR_NECROSIS_FACTOR_PATHWAY
0.17955 0.00000CORUM_SPLICEOSOME
0.16057 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.14796 0.17979ZHANG_PROLIFERATING_VS_QUIESCENT
0.05491 0.06060HUMMEL_BURKITTS_LYMPHOMA_DN
0.08578 0.11172KEGG_APOPTOSIS
0.05961 0.04509NCI_DEGRADATION_OF_BETA_CATENIN_BY_THE_DESTRUCTION_COMPLEX
0.04701 0.00000SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_DN
0.03853 0.00000DODD_NASOPHARYNGEAL_CARCINOMA_DN
0.06179 0.05799CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN
0.02432 0.05376HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.00034 0.01383CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN
0.00020 0.10050NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN
0.00810 0.00000MISSIAGLIA_REGULATED_BY_METHYLATION_UP
0.03036 0.19891NCI_ATF2_PATHWAY
0.14493 0.15533CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_CHUK_BTRC_NFKB2_PPP6C_REL_CUL1_IKBKE_SAPS2_SAPS1_ANKRD28_RELA_SKP1
0.01832 0.08067GEORGANTAS_HSC_MARKERS
0.04559 0.00000MITSIADES_RESPONSE_TO_APLIDIN_DN
0.07883 0.00000TARTE_PLASMA_CELL_VS_PLASMABLAST_DN
0.09861 0.01386CROONQUIST_STROMAL_STIMULATION_UP
0.02156 0.07904KHETCHOUMIAN_TRIM24_TARGETS_UP
0.12289 0.10965SEMBA_FHIT_TARGETS_UP
0.00695 0.00296HORIUCHI_WTAP_TARGETS_UP
0.08304 0.08416CORUM_PA28-20S_PROTEASOME
0.10354 0.00489ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_UP
0.03089 0.10663RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN
0.02167 0.11419CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN
0.03087 0.04566CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN
0.01840 0.05738TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN
0.16976 0.03308SCHAVOLT_TARGETS_OF_TP53_AND_TP63
0.00687 0.17576MORI_PRE_BI_LYMPHOCYTE_DN
0.11870 0.02261DER_IFN_BETA_RESPONSE_UP
0.01803 0.04303DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP
0.06964 0.10056DIRMEIER_LMP1_RESPONSE_LATE_UP
0.11487 0.00000CAIRO_HEPATOBLASTOMA_CLASSES_UP
0.11520 0.03207GALI_TP53_TARGETS_APOPTOTIC_UP
0.03498 0.00006BASSO_CD40_SIGNALING_UP
0.00388 0.06403TIAN_TNF_SIGNALING_NOT_VIA_NFKB
0.00022 0.05507NAGASHIMA_NRG1_SIGNALING_UP
0.16651 0.02397MARZEC_IL2_SIGNALING_UP
0.09092 0.11328ZERBINI_RESPONSE_TO_SULINDAC_UP
0.02045 0.07318CROMER_TUMORIGENESIS_UP
0.03706 0.13001FRIDMAN_SENESCENCE_UP
0.01205 0.05329FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.08209 0.11135SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_DN
0.12426 0.00000CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP
0.19215 0.00000PUJANA_XPRSS_INT_NETWORK
0.15101 0.00000SANA_RESPONSE_TO_IFNG_UP
0.10985 0.00000BENPORATH_CYCLING_GENES
0.05320 0.14766REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G
0.02602 0.05362ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN
0.00054 0.13514ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN
0.07559 0.02956WU_HBX_TARGETS_1_UP
0.13874 0.10451KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_4NQO_IN_OLD
0.09813 0.15691REACTOME_BOTULINUM_NEUROTOXICITY
0.00648 0.14881KANNAN_TP53_TARGETS_UP
0.00050 0.07447CHEN_HOXA5_TARGETS_9HR_UP
0.07746 0.11144NETPATH_IL_5_PATHWAY_UP
0.02093 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.03319 0.10436DAZARD_UV_RESPONSE_CLUSTER_G24
0.11160 0.00000GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.01005 0.00015CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP
0.16966 0.13415MURAKAMI_UV_RESPONSE_6HR_UP
0.00031 0.07657BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
0.02474 0.02259WANG_METHYLATED_IN_BREAST_CANCER
0.15815 0.11294LIU_TARGETS_OF_VMYB_VS_CMYB_DN
0.19023 0.10487ODONNELL_TARGETS_OF_MYC_AND_TFRC_UP
0.02922 0.07804KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_GAMMA_IN_WS
0.09084 0.03806BIOCARTA_IL7_PATHWAY
0.03747 0.00000CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP
0.09237 0.13187STREICHER_LSM1_TARGETS_UP
0.00761 0.05251LINDSTEDT_DENDRITIC_CELL_MATURATION_C
0.13868 0.09533HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN
0.00018 0.00784ELVIDGE_HYPOXIA_BY_DMOG_UP
0.18309 0.00000WONG_EMBRYONIC_STEM_CELL_CORE
0.02681 0.00000VANTVEER_BREAST_CANCER_METASTASIS_DN
0.01752 0.14093BIOCARTA_IL2RB_PATHWAY
0.01851 0.01525OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.16445 0.00000PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP
0.10106 0.11780BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP
0.00850 0.05087RUTELLA_RESPONSE_TO_HGF_UP
0.06801 0.13571HOSHIDA_LIVER_CANCER_LATE_RECURRENCE_UP
0.00000 0.00000PRAMOONJAGO_SOX4_TARGETS_UP
0.00267 0.00605PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.07009 0.11573YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1
0.00071 0.07855ELVIDGE_HIF1A_TARGETS_DN
0.18923 0.00000SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_UP
0.11910 0.00000LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN
0.04818 0.00000PAL_PRMT5_TARGETS_UP
0.16372 0.00005LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.10355 0.06419RUGO_UV_RESPONSE
0.00034 0.02232ELVIDGE_HYPOXIA_UP
0.13246 0.04693BIOCARTA_BIOPEPTIDES_PATHWAY
0.11107 0.00000BROWNE_INTERFERON_RESPONSIVE_GENES
0.16358 0.00000CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN
0.10802 0.08284NCI_IL6_7PATHWAY
0.02406 0.00000RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP
0.11001 0.00000KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN
0.14828 0.02138TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP
0.00315 0.05475NUYTTEN_NIPP1_TARGETS_UP
0.04474 0.08675ST_TYPE_I_INTERFERON_PATHWAY
0.07577 0.04157FRIDMAN_IMMORTALIZATION_DN
0.04823 0.00000PUJANA_CHEK2_PCC_NETWORK
0.12713 0.09306AKL_HTLV1_INFECTION_DN
0.17463 0.00000KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.18329 0.00000PYEON_HPV_POSITIVE_TUMORS_UP
0.00276 0.00779NUYTTEN_EZH2_TARGETS_UP
0.05455 0.00215DUTTA_APOPTOSIS_VIA_NFKB
0.11205 0.16323KRISHNAN_FURIN_TARGETS_UP
0.08905 0.00294DIRMEIER_LMP1_RESPONSE_EARLY
0.07354 0.04727NCI_VPU_MEDIATED_DEGRADATION_OF_CD4
0.04095 0.05265KYNG_ENVIRONMENTAL_STRESS_RESPONSE_UP
0.10530 0.00000LINDGREN_BLADDER_CANCER_CLUSTER_3_UP
0.11282 0.00000ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.03102 0.01033ONDER_CDH1_TARGETS_3_DN
0.01828 0.08197RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP
0.09080 0.12805GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_UP
0.13119 0.04736NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP
0.01549 0.01386WINTER_HYPOXIA_METAGENE
0.07843 0.00000NCI_SNRNP_ASSEMBLY
0.04821 0.19779NEWMAN_ERCC6_TARGETS_UP
0.01570 0.06736GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP
0.01680 0.00000FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.05824 0.11407REACTOME_P53_INDEPENDENT_DNA_DAMAGE_RESPONSE
0.02405 0.02093SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER
0.07078 0.00000ZHANG_BREAST_CANCER_PROGENITORS_UP
0.18659 0.00000BLUM_RESPONSE_TO_SALIRASIB_DN
0.07319 0.11156NETPATH_TNF_ALPHA_PATHWAY_UP
0.17444 0.07808VETTER_TARGETS_OF_PRKCA_AND_ETS1_DN
0.00310 0.05480GESERICK_TERT_TARGETS_DN
0.00320 0.07807AMIT_SERUM_RESPONSE_120_MCF10A
0.11131 0.10685REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE
0.18632 0.00356NCI_IL1PATHWAY
0.01104 0.00136SESTO_RESPONSE_TO_UV_C3
0.00847 0.00667BIOCARTA_PDGF_PATHWAY
0.03258 0.00426GEISS_RESPONSE_TO_DSRNA_UP
0.00780 0.00111BIOCARTA_EGF_PATHWAY
0.03598 0.00145GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN
0.05363 0.00000WEI_MYCN_TARGETS_WITH_E_BOX
0.04532 0.02740BIOCARTA_TPO_PATHWAY
0.00920 0.12988GRUETZMANN_PANCREATIC_CANCER_UP
0.02658 0.00000VECCHI_GASTRIC_CANCER_EARLY_UP
0.05741 0.19567KEGG_PROTEASOME
0.04102 0.17661OKUMURA_INFLAMMATORY_RESPONSE_LPS
0.06587 0.02142LEE_LIVER_CANCER_HEPATOBLAST
0.00045 0.09324NAGASHIMA_EGF_SIGNALING_UP
0.01300 0.02649AMIT_DELAYED_EARLY_GENES
0.09030 0.00000YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_17
0.04449 0.00000BENPORATH_PROLIFERATION
0.00090 0.00467AMIT_EGF_RESPONSE_60_MCF10A
0.17017 0.00005NOJIMA_SFRP2_TARGETS_UP
0.07352 0.00000NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP
0.01878 0.01391OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.01189 0.08510SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP
0.11429 0.00000KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN
0.04385 0.17140NETPATH_EGFR1_PATHWAY_DOWN
0.00548 0.00822LEONARD_HYPOXIA
0.10869 0.06301BERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_UP
0.18975 0.12822REACTOME_CTLA4_INHIBITORY_SIGNALING
0.11228 0.06268NCI_NFKAPPABATYPICALPATHWAY
0.04955 0.00000BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN
0.19264 0.06650LEE_LIVER_CANCER_DENA_UP
0.16355 0.05595YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_9
0.15208 0.00054NETPATH_IL_7_PATHWAY
0.01436 0.13470ONDER_CDH1_SIGNALING_VIA_CTNNB1
0.04993 0.02725GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN
0.09090 0.05098ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP
0.15502 0.00016MAHADEVAN_RESPONSE_TO_MP470_DN
0.00460 0.16665RIGGINS_TAMOXIFEN_RESISTANCE_DN
0.08161 0.00000TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP
0.10031 0.05400HARRIS_HYPOXIA
0.12500 0.00457FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN
0.02323 0.11437KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP
0.03918 0.03196RUGO_ENVIRONMENTAL_STRESS_RESPONSE_UP
0.08124 0.00000REACTOME_METABOLISM_OF_RNA
0.08229 0.00012SOUCEK_MYC_TARGETS
0.04247 0.10145GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_LIGHTYELLOW_UP
0.11163 0.13151YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6
0.04689 0.10012IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP
0.08960 0.01616ZHAN_MULTIPLE_MYELOMA_LB_DN
0.02403 0.06300TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP
0.18885 0.00000GOLDRATH_ANTIGEN_RESPONSE
0.09034 0.00315SHAFFER_IRF4_MULTIPLE_MYELOMA_PROGRAM
0.00093 0.00118BILD_HRAS_ONCOGENIC_SIGNATURE
0.01216 0.00000LIANG_SILENCED_BY_METHYLATION_2
0.03237 0.00011DAUER_STAT3_TARGETS_UP
0.11860 0.00081DER_IFN_ALPHA_RESPONSE_UP
0.05921 0.00208LEE_LIVER_CANCER_ACOX1_UP
0.04093 0.11301PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN
0.03619 0.03296DAZARD_UV_RESPONSE_CLUSTER_G2
0.07960 0.16540AMUNDSON_DNA_DAMAGE_RESPONSE_TP53
0.05981 0.00000WINNEPENNINCKX_MELANOMA_METASTASIS_UP
0.03113 0.00000SCHUHMACHER_MYC_TARGETS_UP
0.00737 0.01845AMIT_SERUM_RESPONSE_40_MCF10A
0.00231 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.01834 0.16417GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP
0.18318 0.12900HELLER_SILENCED_BY_METHYLATION_DN
0.05057 0.15084BIERIE_INFLAMMATORY_RESPONSE_TGFB1
0.15203 0.00000SANA_TNF_SIGNALING_UP
0.15156 0.19319SENESE_HDAC1_AND_HDAC2_TARGETS_UP
0.00297 0.09938ONDER_CDH1_TARGETS_2_DN
0.08012 0.07547AMIT_EGF_RESPONSE_240_HELA
0.13021 0.15123REACTOME_STABILIZATION_OF_P53
0.05117 0.04850NCI_REGULATION_OF_ORNITHINE_DECARBOXYLASE__ODC_
0.14800 0.16459MAINA_VHL_TARGETS_DN
0.04471 0.00000BIDUS_METASTASIS_UP
0.11522 0.00034CASTELLANO_NRAS_TARGETS_UP
0.00067 0.02116HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00000 0.08234UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.04179 0.00331JISON_SICKLE_CELL_DISEASE_UP
0.14884 0.00000KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
0.05639 0.01890NCI_NFKAPPABCANONICALPATHWAY
0.12711 0.00000KEGG_CELL_CYCLE
0.08775 0.10586XU_HGF_SIGNALING_NOT_VIA_AKT1_48HR_UP
0.09369 0.05109DASU_IL6_SIGNALING_UP
0.02097 0.00000FARMER_BREAST_CANCER_CLUSTER_2
0.16635 0.07512NETPATH_IL_2_PATHWAY_UP
0.03108 0.02537HUPER_BREAST_BASAL_VS_LUMINAL_UP
0.03864 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.06985 0.15310NCI_PDGFRBPATHWAY
0.01824 0.03751ZUCCHI_METASTASIS_DN