BICLUSTER_ID : UPREG-128
PATHOGENS /2/ : lactobacillus acidophilus,helicobacter pylori
TARGETS /26/ : LCN2, CCL20, PDE4B, CCL2, CD40, TNFRSF1B, GLA, CD80, VCAM1, MTHFD2, GCH1, CCL5, SAT1, PIM1, SNRPA, NFKB1, MTHFR, XDH, HMOX1, WARS, IL6, SERPINE1, PTGS2, ICAM1, TLR2, TNF
Gene SetLeading Edge Genes
NETPATH IL 1 PATHWAY UPGTF2F1, RHOB, CSF3, CCL20, LCN2, CCL2, NFKBIE, MTHFD2, CCL7, PIM2, INHBA, CXCL2, CSF2, SOD2, NFKB1, BIRC3, LIF, CXCL1, PLK2, WARS, TNFAIP6, CXCL5, IL6, PTGS2, SERPINE1, PBEF1, ZFP36, ICAM1
NETPATH IL 2 PATHWAY UPPFKFB3, PDE4B, FRMD4B, TNFRSF1B, RBL1, NR4A2, MTHFD2, IL4R, FURIN, LAPTM4B, PIM1, CSF2, CFLAR, NFKB1, KLF6, MFHAS1, LIF, WARS, CD69, GADD45G, NFIL3, SAMHD1, FAS, IL6, SERPINE1, PBEF1, ICAM1, IRF1, ANK2, UPP1, TNF
GERY CEBP TARGETSGADD45B, LCN2, EREG, DDIT3, GLA, CD47, FGF7, GCH1, PIM1, SAT1, MAFK, DNAJB10, PTX3, ZFAND2A, HMOX1, XDH, CXCL1, JUNB, MYD116, GADD45G, CXCL5, ATF3, SAA3P
NETPATH IL 4 PATHWAY DOWNCCL20, GADD45B, CDKN1A, CCL2, GBP2, DDIT4, IL6, GEM, LY96, PTGS2, ICAM1, IRF1, BCL6, CXCL2, TLR2, TNF
NETPATH IL 5 PATHWAY UPNFKBIB, PLSCR1, PDE4B, NFKB2, NFKBIE, CCL2, HIF1A, PIM1, RELB, MYD88, CASP4, NFKB1, BIRC3, REL, TBK1, NFIL3, RAB21, ICAM1, UPP1
NETPATH IL 4 PATHWAY UPDAAM1, CCL2, BCL2L11, ELL2, ARID5B, IL4R, VCAM1, IL1RN, INHBA, RIPK2, NFKB1, MTHFR, MXD1, REL, IBRDC3, CITED2, BCL3, NFIL3, IL6, TIMP3, JAG1, SLC11A2, UPP1
NCI IL23PATHWAYNFKB1, IL6, CXCL1, IL23A, CCL2, TNF
NETPATH IL 9 PATHWAY UPLCN2, CCL2, JUNB, SELL, BCL3, CITED2, IL5RA, CCL7, PIM1
NCI TNFPATHWAYNFKB1, BIRC3, TRAF2, CYLD, MAP3K7IP2, BIRC2, TNFRSF1B, RELA, TRAF1, SQSTM1, TNFAIP3, RFFL, TNF
ST TUMOR NECROSIS FACTOR PATHWAYNFKB1, NFKBIB, BIRC3, NFKB2, NFKBIE, TRAF2, BIRC2, TNFRSF1B, TNFAIP3, CFLAR, TNF
NETPATH TNF ALPHA PATHWAYNKIRAS2, NFKBIB, TRAF4, NFKB2, KTN1, NFKBIE, TRAF2, MAP3K8, TNFRSF1B, BIRC2, IKBKE, TRAF1, SUMO1, RIPK2, RELB, NFKBIZ, CFLAR, NFKB1, GAB1, BIRC3, TNIP1, REL, BCL3, TBK1, TNFAIP3, TANK, FBXW11, TNF
NETPATH IL 3 PATHWAY UPNFIL3, CCL7, CCL2, PIM1, TNF
NETPATH IL 7 PATHWAY UPSLC3A2, CXCL5, FAS, CXCL1, CCL5, CXCL2, CD80
SA MMP CYTOKINE CONNECTIONSELL, TNFRSF1B, TGFB2, TNF
NETPATH IL 6 PATHWAY UPGADD45B, CXCL1, JUNB, IGFBP4, CITED2, BCL3, MAP3K8, ZFP36, IRF1, PIM1, TNF
NCI CD40 PATHWAYNFKB1, BIRC3, TRAF2, CD40, BIRC2, TRAF1, TNFAIP3, CBLB
NCI NFKAPPABCANONICALPATHWAYNFKB1, CYLD, BIRC2, RELA, TNFAIP3, RIPK2, TNF, FBXW11
NCI MRNA SPLICING MAJOR PATHWAYSNRPE, SF3A2, HNRPH1, HNRPD, SNRPD3, CCAR1, WDR57, SNRPB, SF3B3, SNRPF, SNRPA, SNRPA1, U2AF2, POLR2G, DHX38, PHF5A, POLR2E, POLR2D, EFTUD2, SNRPD1, POLR2H, SNRP70, RNPS1, SF3B1, U2AF1, CSTF1, RBMX
NCI IL12 2PATHWAYNFKB1, GADD45B, NFKB2, RELB, RIPK2, GADD45G
CORUM SPLICEOSOMEPPIE, SNRPE, TCERG1, SF3A2, BCAS2, ACIN1, SNRPB, SF3B3, SNRPF, AQR, SNRPA1, SNRPA, U2AF2, SKIV2L2, EFTUD2, DHX9, THOC3, RNPS1, LSM4, U2AF1
CORUM NFKB1-NFKB2-REL-RELA-RELB COMPLEXNFKB1, REL, NFKB2, RELB, RELA
NCI NFKAPPABALTERNATIVEPATHWAYNFKB1, NFKB2, RELB, FBXW11
NETPATH IL 1 PATHWAYSQSTM1, NFKB1, NFKBIB, IL1RN, MYD88, IRAK3
CORUM NFKB1-NFKB2-RELA-RELB COMPLEXNFKB1, NFKB2, RELB, RELA
NCI IL1PATHWAYSQSTM1, NFKB1, IL1RN, MYD88, IRAK3
NCI NFKAPPABATYPICALPATHWAYNFKB1, REL, BCL3, FBXW11
CORUM CHUK-NFKB2-REL-IKBKG-SPAG9-NFKB1-NFKBIE-COPB2-TNIP1-NFKBIA-RELA-TNIP2 COMPLEXNFKB1, REL, TNIP1, NFKB2, NFKBIE
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
BIOCARTA STEM PATHWAY
BIOCARTA NFKB PATHWAY
MAHAJAN RESPONSE TO IL1A UP
WEINMANN ADAPTATION TO HYPOXIA DN
BIOCARTA IL6 PATHWAY
CHUANG OXIDATIVE STRESS RESPONSE UP
KEGG GRAFT VERSUS HOST DISEASE
REACTOME PEPTIDE LIGAND BINDING RECEPTORS
LINDSTEDT DENDRITIC CELL MATURATION B
BIOCARTA IL1R PATHWAY
BIOCARTA RELA PATHWAY
RASHI RESPONSE TO IONIZING RADIATION 2
RADAEVA RESPONSE TO IFNA1 UP
ODONNELL TFRC TARGETS UP
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
NCI CELL SURFACE INTERACTIONS AT THE VASCULAR WALL
REACTOME TRNA AMINOACYLATION
AMIT EGF RESPONSE 40 HELA
MITSIADES RESPONSE TO APLIDIN UP
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
SCIBETTA KDM5B TARGETS UP
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION ERYTHROCYTE UP
HINATA NFKB TARGETS KERATINOCYTE UP
RUTELLA RESPONSE TO CSF2RB AND IL4 UP
DOUGLAS BMI1 TARGETS DN
KOKKINAKIS METHIONINE DEPRIVATION 96HR UP
MARKEY RB1 ACUTE LOF UP
SCHEIDEREIT IKK INTERACTING PROTEINS
AMIT SERUM RESPONSE 60 MCF10A
POOLA INVASIVE BREAST CANCER UP
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
BIOCARTA CD40 PATHWAY
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLUE UP
DEBOSSCHER NFKB TARGETS REPRESSED BY GLUCOCORTICOIDS
AMIT EGF RESPONSE 120 HELA
BIOCARTA RANKL PATHWAY
DANG REGULATED BY MYC DN
MCLACHLAN DENTAL CARIES UP
PODAR RESPONSE TO ADAPHOSTIN UP
SHAFFER IRF4 TARGETS IN PLASMA CELL VS MATURE B LYMPHOCYTE
LEE LIVER CANCER E2F1 UP
REACTOME HUMAN TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX
HELLER SILENCED BY METHYLATION UP
LAU APOPTOSIS CDKN2A UP
SMID BREAST CANCER LUMINAL B DN
ZHOU INFLAMMATORY RESPONSE LPS UP
WONG ENDMETRIUM CANCER UP
BERENJENO TRANSFORMED BY RHOA UP
CORUM REL-MAP3K8-RELA-TNIP2-PAPOLA COMPLEX
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL
REACTOME TOLL LIKE RECEPTOR 4 CASCADE
VERHAAK AML WITH NPM1 MUTATED UP
BROCKE APOPTOSIS REVERSED BY IL6
REACTOME CD28 CO STIMULATION
CORUM IKBEPSILON-RELA-CREL COMPLEX
NCI ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS
TIAN TNF SIGNALING VIA NFKB
HUMMEL BURKITTS LYMPHOMA DN
KEGG TOLL LIKE RECEPTOR SIGNALING PATHWAY
KEGG APOPTOSIS
REACTOME FORMATION AND MATURATION OF MRNA TRANSCRIPT
NCI MRNA SPLICING MINOR PATHWAY
HINATA NFKB TARGETS FIBROBLAST UP
CHARAFE BREAST CANCER LUMINAL VS BASAL DN
NAKAMURA TUMOR ZONE PERIPHERAL VS CENTRAL DN
MISSIAGLIA REGULATED BY METHYLATION UP
NCI ATF2 PATHWAY
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX CHUK BTRC NFKB2 PPP6C REL CUL1 IKBKE SAPS2 SAPS1 ANKRD28 RELA SKP1
GEORGANTAS HSC MARKERS
BROWNE HCMV INFECTION 12HR UP
SESTO RESPONSE TO UV C1
CROONQUIST STROMAL STIMULATION UP
REACTOME MRNA SPLICING
BOYLAN MULTIPLE MYELOMA C DN
SIMBULAN UV RESPONSE NORMAL UP
DACOSTA ERCC3 ALLELE XPCS VS TTD UP
HORIUCHI WTAP TARGETS UP
REACTOME ELONGATION AND PROCESSING OF CAPPED TRANSCRIPTS
RUTELLA RESPONSE TO CSF2RB AND IL4 DN
BIOCARTA SODD PATHWAY
KEGG JAK STAT SIGNALING PATHWAY
TSAI DNAJB4 TARGETS UP
MORI PRE BI LYMPHOCYTE DN
DER IFN BETA RESPONSE UP
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP
NCI REGULATED PROTEOLYSIS OF P75NTR
DIRMEIER LMP1 RESPONSE LATE UP
NCI FASL CD95L SIGNALING
GALI TP53 TARGETS APOPTOTIC UP
KEGG ADIPOCYTOKINE SIGNALING PATHWAY
MUELLER METHYLATED IN GLIOBLASTOMA
BASSO CD40 SIGNALING UP
NAGASHIMA NRG1 SIGNALING UP
MARZEC IL2 SIGNALING UP
SCHLOSSER MYC TARGETS REPRESSED BY SERUM
BIOCARTA BLYMPHOCYTE PATHWAY
KEGG AMINOACYL TRNA BIOSYNTHESIS
ZERBINI RESPONSE TO SULINDAC UP
WU HBX TARGETS 2 DN
NETPATH B CELL RECEPTOR PATHWAY UP
MAHADEVAN RESPONSE TO MP470 UP
FERRARI RESPONSE TO FENRETINIDE UP
KEGG RIG I LIKE RECEPTOR SIGNALING PATHWAY
BIOCARTA TID PATHWAY
GARCIA TARGETS OF FLI1 AND DAX1 DN
AMUNDSON GAMMA RADIATION RESISTANCE
BIOCARTA CTL PATHWAY
ZHANG ANTIVIRAL RESPONSE TO RIBAVIRIN DN
KEGG LEISHMANIA INFECTION
CORUM DEATH INDUCED SIGNALING COMPLEX DISC FAS FADD CASP8 CFLAR MEMBRANE-ASSOCIATED CD95L INDUCED
CHEN HOXA5 TARGETS 9HR UP
BIOCARTA DEATH PATHWAY
SEKI INFLAMMATORY RESPONSE LPS UP
GRAHAM CML QUIESCENT VS CML DIVIDING UP
CONCANNON APOPTOSIS BY EPOXOMICIN UP
PARK TRETINOIN RESPONSE AND PML RARA FUSION
BUYTAERT PHOTODYNAMIC THERAPY STRESS UP
FOSTER INFLAMMATORY RESPONSE LPS UP
REACTOME MRNA SPLICING MINOR PATHWAY
LIU TARGETS OF VMYB VS CMYB DN
REACTOME TOLL RECEPTOR CASCADES
ODONNELL TARGETS OF MYC AND TFRC UP
REACTOME P75NTR SIGNALS VIA NFKB
KEGG CYTOSOLIC DNA SENSING PATHWAY
STREICHER LSM1 TARGETS UP
BIOCARTA GRANULOCYTES PATHWAY
BIOCARTA TNFR2 PATHWAY
REACTOME ACTIVATED TLR4 SIGNALLING
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX
HESS TARGETS OF HOXA9 AND MEIS1 DN
ELVIDGE HYPOXIA BY DMOG UP
BIOCARTA TOLL PATHWAY
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
BERTUCCI MEDULLARY VS DUCTAL BREAST CANCER UP
CORUM DEATH INDUCED SIGNALING COMPLEX II FADD CASP8 CFLAR CYTOSOLIC CD95L INDUCED
RUTELLA RESPONSE TO HGF UP
PRAMOONJAGO SOX4 TARGETS UP
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 1
LENAOUR DENDRITIC CELL MATURATION UP
ICHIBA GRAFT VERSUS HOST DISEASE D7 UP
LINDSTEDT DENDRITIC CELL MATURATION A
ELVIDGE HYPOXIA UP
BROWNE INTERFERON RESPONSIVE GENES
NCI IL6 7PATHWAY
CORUM DEATH-INDUCING SIGNALING COMPLEX DISC TYPE I CELLS ASSOCIATED STIMULATED
REACTOME SIGNALING IN IMMUNE SYSTEM
BIOCARTA LAIR PATHWAY
NUYTTEN NIPP1 TARGETS UP
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
CORUM FAS-FADD-CASP8 COMPLEX
MURATA VIRULENCE OF H PILORI
VART KSHV INFECTION ANGIOGENIC MARKERS UP
BIOCARTA LYM PATHWAY
GILMORE CORE NFKB PATHWAY
NUYTTEN EZH2 TARGETS UP
DUTTA APOPTOSIS VIA NFKB
TSAI RESPONSE TO IONIZING RADIATION
DIRMEIER LMP1 RESPONSE EARLY
DER IFN GAMMA RESPONSE UP
KEGG INTESTINAL IMMUNE NETWORK FOR IGA PRODUCTION
ZHOU INFLAMMATORY RESPONSE LIVE UP
ONDER CDH1 TARGETS 3 DN
RUTELLA RESPONSE TO HGF VS CSF2RB AND IL4 UP
BIOCARTA ERYTH PATHWAY
NAKAYAMA SOFT TISSUE TUMORS PCA1 UP
WINTER HYPOXIA METAGENE
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX CHUK KPNA3 NFKB2 NFKBIB REL IKBKG NFKB1 NFKBIE RELB NFKBIA RELA TNIP2
REACTOME TOLL LIKE RECEPTOR 9 CASCADE
ISHIKAWA STING SIGNALING
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS TURQUOISE UP
TAVOR CEBPA TARGETS UP
FOSTER INFLAMMATORY RESPONSE LPS DN
GAURNIER PSMD4 TARGETS
OSAWA TNF TARGETS
BIOCARTA HIVNEF PATHWAY
NETPATH TNF ALPHA PATHWAY UP
MARKEY RB1 CHRONIC LOF DN
NCI ACTIVATION OF THE PRE REPLICATIVE COMPLEX
NCI AMB2 NEUTROPHILS PATHWAY
AMIT SERUM RESPONSE 120 MCF10A
BROWNE HCMV INFECTION 2HR UP
SESTO RESPONSE TO UV C3
REACTOME DEATH RECEPTOR SIGNALLING
GEISS RESPONSE TO DSRNA UP
GRAHAM CML DIVIDING VS NORMAL QUIESCENT DN
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 1
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX RPL6 RPL30 RPS13 CHUK DDX3X NFKB2 NFKBIB REL IKBKG NFKB1 MAP3K8 RELB GLG1 NFKBIA RELA TNIP2 GTF2I
CORUM FAS-FADD-CASP8-CASP10 COMPLEX
BOYLAN MULTIPLE MYELOMA C CLUSTER DN
ZHOU INFLAMMATORY RESPONSE FIMA UP
ZHU CMV ALL UP
NCI HIF2PATHWAY
ABE VEGFA TARGETS 2HR
LEE LIVER CANCER HEPATOBLAST
NAGASHIMA EGF SIGNALING UP
AMIT EGF RESPONSE 60 MCF10A
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
NOJIMA SFRP2 TARGETS UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
NETPATH EGFR1 PATHWAY DOWN
LEONARD HYPOXIA
BIOCARTA EPONFKB PATHWAY
RODRIGUES THYROID CARCINOMA DN
AUJLA IL22 AND IL17A SIGNALING
JIANG HYPOXIA NORMAL
WALLACE PROSTATE CANCER RACE UP
NETPATH IL 7 PATHWAY DOWN
BASAKI YBX1 TARGETS UP
REACTOME MYD88 CASCADE
WIELAND UP BY HBV INFECTION
ONDER CDH1 SIGNALING VIA CTNNB1
GUTIERREZ WALDENSTROEMS MACROGLOBULINEMIA 1 DN
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING
MAHADEVAN RESPONSE TO MP470 DN
UROSEVIC RESPONSE TO IMIQUIMOD
NAKAMURA CANCER MICROENVIRONMENT DN
HARRIS HYPOXIA
KOKKINAKIS METHIONINE DEPRIVATION 48HR UP
CASORELLI ACUTE PROMYELOCYTIC LEUKEMIA UP
REACTOME INNATE IMMUNITY SIGNALING
NCI IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL
SOUCEK MYC TARGETS
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS LIGHTYELLOW UP
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 6HR DN
NCI DOWNSTREAM TCR SIGNALING
BILD HRAS ONCOGENIC SIGNATURE
LIANG SILENCED BY METHYLATION 2
DAUER STAT3 TARGETS UP
DER IFN ALPHA RESPONSE UP
ST FAS SIGNALING PATHWAY
BIOCARTA GSK3 PATHWAY
DAZARD UV RESPONSE CLUSTER G2
MCLACHLAN DENTAL CARIES DN
AMIT SERUM RESPONSE 40 MCF10A
MANALO HYPOXIA DN
CORUM DISC COMPLEX
BROWNE HCMV INFECTION 4HR UP
WONG ENDOMETRIAL CANCER LATE
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
BIOCARTA STRESS PATHWAY
ZHU CMV 8 HR UP
SANA TNF SIGNALING UP
BIOCARTA INFLAM PATHWAY
NCI IL27PATHWAY
XU HGF TARGETS INDUCED BY AKT1 6HR
ONDER CDH1 TARGETS 2 DN
AMIT EGF RESPONSE 240 HELA
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 2
KEGG CHEMOKINE SIGNALING PATHWAY
KLEIN TARGETS OF BCR ABL1 FUSION
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
DASU IL6 SIGNALING UP
NETPATH T CELL RECEPTOR PATHWAY UP
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
ZUCCHI METASTASIS DN
NUNODA RESPONSE TO DASATINIB IMATINIB DN
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
helicobacter pylori kx1 mgeplactobacillus acidophilusGeneSet Name
0.00000 0.00114NETPATH_IL_1_PATHWAY_UP
0.02575 0.01173NETPATH_IL_2_PATHWAY_UP
0.00133 0.00427GERY_CEBP_TARGETS
0.00002 0.00012NETPATH_IL_4_PATHWAY_DOWN
0.00021 0.01533NETPATH_IL_5_PATHWAY_UP
0.00423 0.01511NETPATH_IL_4_PATHWAY_UP
0.00589 0.00000NCI_IL23PATHWAY
0.00013 0.01316NETPATH_IL_9_PATHWAY_UP
0.00024 0.00465NCI_TNFPATHWAY
0.00032 0.00006ST_TUMOR_NECROSIS_FACTOR_PATHWAY
0.00091 0.02931NETPATH_TNF_ALPHA_PATHWAY
0.03326 0.00372NETPATH_IL_3_PATHWAY_UP
0.00294 0.06237NETPATH_IL_7_PATHWAY_UP
0.01005 0.11732SA_MMP_CYTOKINE_CONNECTION
0.00236 0.00006NETPATH_IL_6_PATHWAY_UP
0.00012 0.02747NCI_CD40_PATHWAY
0.00742 0.00905NCI_NFKAPPABCANONICALPATHWAY
0.00020 0.00000NCI_MRNA_SPLICING___MAJOR_PATHWAY
0.05996 0.00000NCI_IL12_2PATHWAY
0.03931 0.00000CORUM_SPLICEOSOME
0.00719 0.05429CORUM_NFKB1-NFKB2-REL-RELA-RELB_COMPLEX
0.02162 0.08864NCI_NFKAPPABALTERNATIVEPATHWAY
0.00053 0.10592NETPATH_IL_1_PATHWAY
0.02900 0.11966CORUM_NFKB1-NFKB2-RELA-RELB_COMPLEX
0.06190 0.02751NCI_IL1PATHWAY
0.00461 0.01289NCI_NFKAPPABATYPICALPATHWAY
0.01282 0.01629CORUM_CHUK-NFKB2-REL-IKBKG-SPAG9-NFKB1-NFKBIE-COPB2-TNIP1-NFKBIA-RELA-TNIP2_COMPLEX
0.03509 0.00008GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.02542 0.01289BIOCARTA_STEM_PATHWAY
0.00155 0.01221BIOCARTA_NFKB_PATHWAY
0.00517 0.00430MAHAJAN_RESPONSE_TO_IL1A_UP
0.07109 0.05378WEINMANN_ADAPTATION_TO_HYPOXIA_DN
0.02454 0.13369BIOCARTA_IL6_PATHWAY
0.01119 0.12039CHUANG_OXIDATIVE_STRESS_RESPONSE_UP
0.02385 0.00180KEGG_GRAFT_VERSUS_HOST_DISEASE
0.09639 0.01634REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
0.00000 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00078 0.02532BIOCARTA_IL1R_PATHWAY
0.03110 0.01632BIOCARTA_RELA_PATHWAY
0.00000 0.00034RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.08041 0.00000RADAEVA_RESPONSE_TO_IFNA1_UP
0.00837 0.10276ODONNELL_TFRC_TARGETS_UP
0.00293 0.00648IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.07965 0.06806NCI_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL
0.00973 0.00000REACTOME_TRNA_AMINOACYLATION
0.00125 0.00081AMIT_EGF_RESPONSE_40_HELA
0.00011 0.18043MITSIADES_RESPONSE_TO_APLIDIN_UP
0.00000 0.09352THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.04606 0.13031SCIBETTA_KDM5B_TARGETS_UP
0.10179 0.00372TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP
0.00002 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.11690 0.06788RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP
0.14968 0.02394DOUGLAS_BMI1_TARGETS_DN
0.10157 0.13048KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP
0.07713 0.00000MARKEY_RB1_ACUTE_LOF_UP
0.07688 0.13708SCHEIDEREIT_IKK_INTERACTING_PROTEINS
0.00013 0.17039AMIT_SERUM_RESPONSE_60_MCF10A
0.13876 0.11511POOLA_INVASIVE_BREAST_CANCER_UP
0.00030 0.00000REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA
0.00018 0.00017REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
0.02889 0.03092BIOCARTA_CD40_PATHWAY
0.00007 0.01803GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP
0.09299 0.07015DEBOSSCHER_NFKB_TARGETS_REPRESSED_BY_GLUCOCORTICOIDS
0.00003 0.09453AMIT_EGF_RESPONSE_120_HELA
0.02627 0.00384BIOCARTA_RANKL_PATHWAY
0.13597 0.13620DANG_REGULATED_BY_MYC_DN
0.00018 0.00667MCLACHLAN_DENTAL_CARIES_UP
0.00015 0.00831PODAR_RESPONSE_TO_ADAPHOSTIN_UP
0.17649 0.12293SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE
0.17072 0.00852LEE_LIVER_CANCER_E2F1_UP
0.06009 0.03056REACTOME_HUMAN_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX
0.02029 0.00489HELLER_SILENCED_BY_METHYLATION_UP
0.00207 0.15875LAU_APOPTOSIS_CDKN2A_UP
0.17326 0.07352SMID_BREAST_CANCER_LUMINAL_B_DN
0.00307 0.00000ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.19450 0.02529WONG_ENDMETRIUM_CANCER_UP
0.03867 0.00000BERENJENO_TRANSFORMED_BY_RHOA_UP
0.12111 0.05982CORUM_REL-MAP3K8-RELA-TNIP2-PAPOLA_COMPLEX
0.12794 0.00000REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS
0.07216 0.02656REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL
0.09984 0.06205REACTOME_TOLL_LIKE_RECEPTOR_4_CASCADE
0.00063 0.03043VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.01130 0.03083BROCKE_APOPTOSIS_REVERSED_BY_IL6
0.18360 0.01167REACTOME_CD28_CO_STIMULATION
0.10711 0.19417CORUM_IKBEPSILON-RELA-CREL_COMPLEX
0.10061 0.00000NCI_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS
0.00000 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.02445 0.02581HUMMEL_BURKITTS_LYMPHOMA_DN
0.01726 0.00000KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.16656 0.01718KEGG_APOPTOSIS
0.00104 0.00000REACTOME_FORMATION_AND_MATURATION_OF_MRNA_TRANSCRIPT
0.13256 0.00000NCI_MRNA_SPLICING___MINOR_PATHWAY
0.00000 0.01167HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.10553 0.02479CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN
0.15874 0.19505NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN
0.00725 0.00001MISSIAGLIA_REGULATED_BY_METHYLATION_UP
0.02072 0.14551NCI_ATF2_PATHWAY
0.05886 0.07030CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_CHUK_BTRC_NFKB2_PPP6C_REL_CUL1_IKBKE_SAPS2_SAPS1_ANKRD28_RELA_SKP1
0.16428 0.01133GEORGANTAS_HSC_MARKERS
0.05668 0.19772BROWNE_HCMV_INFECTION_12HR_UP
0.00084 0.10290SESTO_RESPONSE_TO_UV_C1
0.03674 0.04711CROONQUIST_STROMAL_STIMULATION_UP
0.00099 0.00000REACTOME_MRNA_SPLICING
0.01898 0.06262BOYLAN_MULTIPLE_MYELOMA_C_DN
0.02203 0.01522SIMBULAN_UV_RESPONSE_NORMAL_UP
0.11957 0.10069DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_UP
0.02539 0.00495HORIUCHI_WTAP_TARGETS_UP
0.00064 0.00000REACTOME_ELONGATION_AND_PROCESSING_OF_CAPPED_TRANSCRIPTS
0.13491 0.10725RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN
0.04850 0.01240BIOCARTA_SODD_PATHWAY
0.09614 0.00000KEGG_JAK_STAT_SIGNALING_PATHWAY
0.02725 0.00463TSAI_DNAJB4_TARGETS_UP
0.13814 0.04496MORI_PRE_BI_LYMPHOCYTE_DN
0.04581 0.00144DER_IFN_BETA_RESPONSE_UP
0.00015 0.00593DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP
0.10723 0.12594NCI_REGULATED_PROTEOLYSIS_OF_P75NTR
0.00800 0.09243DIRMEIER_LMP1_RESPONSE_LATE_UP
0.13255 0.05618NCI_FASL__CD95L_SIGNALING
0.01118 0.00830GALI_TP53_TARGETS_APOPTOTIC_UP
0.12789 0.10763KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY
0.17512 0.17573MUELLER_METHYLATED_IN_GLIOBLASTOMA
0.00077 0.00000BASSO_CD40_SIGNALING_UP
0.00000 0.02256NAGASHIMA_NRG1_SIGNALING_UP
0.04862 0.15147MARZEC_IL2_SIGNALING_UP
0.16013 0.00000SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM
0.09108 0.01164BIOCARTA_BLYMPHOCYTE_PATHWAY
0.02898 0.00000KEGG_AMINOACYL_TRNA_BIOSYNTHESIS
0.00318 0.18728ZERBINI_RESPONSE_TO_SULINDAC_UP
0.00624 0.02392WU_HBX_TARGETS_2_DN
0.01192 0.17292NETPATH_B_CELL_RECEPTOR_PATHWAY_UP
0.00002 0.00272MAHADEVAN_RESPONSE_TO_MP470_UP
0.00008 0.15133FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.00095 0.00006KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00325 0.09391BIOCARTA_TID_PATHWAY
0.06313 0.00000GARCIA_TARGETS_OF_FLI1_AND_DAX1_DN
0.06553 0.13807AMUNDSON_GAMMA_RADIATION_RESISTANCE
0.04722 0.13819BIOCARTA_CTL_PATHWAY
0.05403 0.07388ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN
0.00031 0.00174KEGG_LEISHMANIA_INFECTION
0.05547 0.06561CORUM_DEATH_INDUCED_SIGNALING_COMPLEX_DISC_FAS_FADD_CASP8_CFLAR_MEMBRANE-ASSOCIATED_CD95L_INDUCED
0.00000 0.04051CHEN_HOXA5_TARGETS_9HR_UP
0.05146 0.13894BIOCARTA_DEATH_PATHWAY
0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00937 0.00000GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00002 0.00854CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP
0.03178 0.14509PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION
0.00000 0.03405BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
0.00587 0.00000FOSTER_INFLAMMATORY_RESPONSE_LPS_UP
0.15458 0.00000REACTOME_MRNA_SPLICING_MINOR_PATHWAY
0.00459 0.05963LIU_TARGETS_OF_VMYB_VS_CMYB_DN
0.08039 0.14249REACTOME_TOLL_RECEPTOR_CASCADES
0.07116 0.04832ODONNELL_TARGETS_OF_MYC_AND_TFRC_UP
0.00018 0.17190REACTOME_P75NTR_SIGNALS_VIA_NFKB
0.03185 0.00033KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY
0.12987 0.05250STREICHER_LSM1_TARGETS_UP
0.01647 0.01385BIOCARTA_GRANULOCYTES_PATHWAY
0.00067 0.00403BIOCARTA_TNFR2_PATHWAY
0.07552 0.13698REACTOME_ACTIVATED_TLR4_SIGNALLING
0.18016 0.00000REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX
0.04632 0.04650HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN
0.00023 0.12346ELVIDGE_HYPOXIA_BY_DMOG_UP
0.01652 0.07530BIOCARTA_TOLL_PATHWAY
0.00010 0.00475OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.01985 0.01593BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP
0.16803 0.09523CORUM_DEATH_INDUCED_SIGNALING_COMPLEX_II_FADD_CASP8_CFLAR_CYTOSOLIC_CD95L_INDUCED
0.07973 0.03223RUTELLA_RESPONSE_TO_HGF_UP
0.00000 0.00031PRAMOONJAGO_SOX4_TARGETS_UP
0.00002 0.00034PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.00221 0.08170YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1
0.19240 0.13411LENAOUR_DENDRITIC_CELL_MATURATION_UP
0.02414 0.00000ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP
0.00015 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00083 0.10353ELVIDGE_HYPOXIA_UP
0.07388 0.00000BROWNE_INTERFERON_RESPONSIVE_GENES
0.04616 0.12322NCI_IL6_7PATHWAY
0.13940 0.13815CORUM_DEATH-INDUCING_SIGNALING_COMPLEX_DISC_TYPE_I_CELLS_ASSOCIATED_STIMULATED
0.13041 0.02614REACTOME_SIGNALING_IN_IMMUNE_SYSTEM
0.00718 0.00383BIOCARTA_LAIR_PATHWAY
0.14102 0.00829NUYTTEN_NIPP1_TARGETS_UP
0.00005 0.00000KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.16785 0.14107CORUM_FAS-FADD-CASP8_COMPLEX
0.01632 0.06667MURATA_VIRULENCE_OF_H_PILORI
0.18244 0.00138VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP
0.02445 0.09025BIOCARTA_LYM_PATHWAY
0.00003 0.00978GILMORE_CORE_NFKB_PATHWAY
0.01257 0.00089NUYTTEN_EZH2_TARGETS_UP
0.00000 0.00233DUTTA_APOPTOSIS_VIA_NFKB
0.00508 0.18848TSAI_RESPONSE_TO_IONIZING_RADIATION
0.00157 0.00007DIRMEIER_LMP1_RESPONSE_EARLY
0.03795 0.00091DER_IFN_GAMMA_RESPONSE_UP
0.16521 0.00200KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION
0.00000 0.00000ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.00085 0.00174ONDER_CDH1_TARGETS_3_DN
0.09618 0.12763RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP
0.09548 0.00077BIOCARTA_ERYTH_PATHWAY
0.02466 0.01636NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP
0.00017 0.11168WINTER_HYPOXIA_METAGENE
0.00204 0.00206CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_CHUK_KPNA3_NFKB2_NFKBIB_REL_IKBKG__NFKB1_NFKBIE_RELB__NFKBIA_RELA_TNIP2
0.05403 0.15710REACTOME_TOLL_LIKE_RECEPTOR_9_CASCADE
0.10515 0.01863ISHIKAWA_STING_SIGNALING
0.00151 0.08350GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP
0.03788 0.10298TAVOR_CEBPA_TARGETS_UP
0.00006 0.00000FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.00002 0.00000GAURNIER_PSMD4_TARGETS
0.06007 0.12892OSAWA_TNF_TARGETS
0.05535 0.18343BIOCARTA_HIVNEF_PATHWAY
0.10562 0.09704NETPATH_TNF_ALPHA_PATHWAY_UP
0.03341 0.03135MARKEY_RB1_CHRONIC_LOF_DN
0.13633 0.00000NCI_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX
0.08278 0.18674NCI_AMB2_NEUTROPHILS_PATHWAY
0.00289 0.01424AMIT_SERUM_RESPONSE_120_MCF10A
0.00034 0.06476BROWNE_HCMV_INFECTION_2HR_UP
0.00438 0.02540SESTO_RESPONSE_TO_UV_C3
0.03102 0.00039REACTOME_DEATH_RECEPTOR_SIGNALLING
0.00000 0.00027GEISS_RESPONSE_TO_DSRNA_UP
0.11276 0.00001GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN
0.15849 0.12179SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1
0.03787 0.03188CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_RPL6_RPL30_RPS13_CHUK_DDX3X_NFKB2_NFKBIB_REL_IKBKG_NFKB1_MAP3K8_RELB_GLG1_NFKBIA_RELA_TNIP2__GTF2I
0.16537 0.12760CORUM_FAS-FADD-CASP8-CASP10_COMPLEX
0.07759 0.01867BOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_DN
0.00157 0.00018ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP
0.01293 0.00466ZHU_CMV_ALL_UP
0.02458 0.12318NCI_HIF2PATHWAY
0.15162 0.11415ABE_VEGFA_TARGETS_2HR
0.07700 0.04137LEE_LIVER_CANCER_HEPATOBLAST
0.00000 0.05878NAGASHIMA_EGF_SIGNALING_UP
0.00002 0.00978AMIT_EGF_RESPONSE_60_MCF10A
0.02218 0.00000KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.00032 0.00685NOJIMA_SFRP2_TARGETS_UP
0.00008 0.00598OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.09276 0.10789NETPATH_EGFR1_PATHWAY_DOWN
0.00002 0.05078LEONARD_HYPOXIA
0.00105 0.08632BIOCARTA_EPONFKB_PATHWAY
0.00156 0.03095RODRIGUES_THYROID_CARCINOMA_DN
0.01124 0.00386AUJLA_IL22_AND_IL17A_SIGNALING
0.04984 0.17292JIANG_HYPOXIA_NORMAL
0.17667 0.00000WALLACE_PROSTATE_CANCER_RACE_UP
0.14176 0.01632NETPATH_IL_7_PATHWAY_DOWN
0.13592 0.00000BASAKI_YBX1_TARGETS_UP
0.03779 0.14657REACTOME_MYD88_CASCADE
0.17121 0.00048WIELAND_UP_BY_HBV_INFECTION
0.00188 0.05066ONDER_CDH1_SIGNALING_VIA_CTNNB1
0.08369 0.02475GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN
0.19433 0.00375REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING
0.00340 0.00321MAHADEVAN_RESPONSE_TO_MP470_DN
0.19498 0.00000UROSEVIC_RESPONSE_TO_IMIQUIMOD
0.08543 0.00000NAKAMURA_CANCER_MICROENVIRONMENT_DN
0.00027 0.18721HARRIS_HYPOXIA
0.04563 0.09320KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP
0.00104 0.15885CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP
0.10693 0.19378REACTOME_INNATE_IMMUNITY_SIGNALING
0.10243 0.00923NCI_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL
0.00011 0.00010SOUCEK_MYC_TARGETS
0.07962 0.11910GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_LIGHTYELLOW_UP
0.00543 0.02438TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN
0.07067 0.16042NCI_DOWNSTREAM_TCR_SIGNALING
0.00029 0.00628BILD_HRAS_ONCOGENIC_SIGNATURE
0.00031 0.00000LIANG_SILENCED_BY_METHYLATION_2
0.00067 0.00259DAUER_STAT3_TARGETS_UP
0.14451 0.00000DER_IFN_ALPHA_RESPONSE_UP
0.16556 0.17297ST_FAS_SIGNALING_PATHWAY
0.14144 0.08861BIOCARTA_GSK3_PATHWAY
0.00079 0.06213DAZARD_UV_RESPONSE_CLUSTER_G2
0.00030 0.01242MCLACHLAN_DENTAL_CARIES_DN
0.00874 0.00031AMIT_SERUM_RESPONSE_40_MCF10A
0.17331 0.00000MANALO_HYPOXIA_DN
0.15926 0.11449CORUM_DISC_COMPLEX
0.00261 0.03781BROWNE_HCMV_INFECTION_4HR_UP
0.03193 0.01701WONG_ENDOMETRIAL_CANCER_LATE
0.00000 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.01749 0.18094BIOCARTA_STRESS_PATHWAY
0.01261 0.00000ZHU_CMV_8_HR_UP
0.00000 0.00000SANA_TNF_SIGNALING_UP
0.05381 0.00000BIOCARTA_INFLAM_PATHWAY
0.10038 0.00000NCI_IL27PATHWAY
0.04723 0.11695XU_HGF_TARGETS_INDUCED_BY_AKT1_6HR
0.03557 0.02211ONDER_CDH1_TARGETS_2_DN
0.09400 0.14571AMIT_EGF_RESPONSE_240_HELA
0.00215 0.11701HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.01185 0.01605SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2
0.12202 0.03796KEGG_CHEMOKINE_SIGNALING_PATHWAY
0.18602 0.07577KLEIN_TARGETS_OF_BCR_ABL1_FUSION
0.00000 0.03748UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.07974 0.15237DASU_IL6_SIGNALING_UP
0.09515 0.18163NETPATH_T_CELL_RECEPTOR_PATHWAY_UP
0.00000 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00723 0.04132ZUCCHI_METASTASIS_DN
0.05462 0.04504NUNODA_RESPONSE_TO_DASATINIB_IMATINIB_DN