BICLUSTER_ID : UPREG-146
PATHOGENS /8/ : escherichia coli,lactobacillus acidophilus,aeromonas caviae,helicobacter pylori,pseudomonas aeruginosa,bifidobacterium bifidum,yersinia enterocolitica,ehrlichia chaffeensis
TARGETS /1/ : TNFRSF1B
Gene SetLeading Edge Genes
NETPATH IL 2 PATHWAY UPPFKFB3, IRF1, TNFRSF1B
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
NETPATH IL 9 PATHWAY UP
MAHAJAN RESPONSE TO IL1A UP
ICHIBA GRAFT VERSUS HOST DISEASE D7 UP
REACTOME PEPTIDE LIGAND BINDING RECEPTORS
LINDSTEDT DENDRITIC CELL MATURATION B
LINDSTEDT DENDRITIC CELL MATURATION A
WALLACE PROSTATE CANCER RACE UP
HORIUCHI WTAP TARGETS UP
WIELAND UP BY HBV INFECTION
NETPATH IL 4 PATHWAY DOWNIRF1
NETPATH IL 7 PATHWAY UPCXCL5, CXCL1
UROSEVIC RESPONSE TO IMIQUIMOD
NCI IL6 7PATHWAY
BROWNE INTERFERON RESPONSIVE GENES
KEGG JAK STAT SIGNALING PATHWAY
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION ERYTHROCYTE UP
DER IFN BETA RESPONSE UP
HINATA NFKB TARGETS KERATINOCYTE UP
MARKEY RB1 ACUTE LOF UP
BASSO CD40 SIGNALING UP
SOUCEK MYC TARGETS
NUYTTEN EZH2 TARGETS UP
DUTTA APOPTOSIS VIA NFKB
DIRMEIER LMP1 RESPONSE EARLY
DER IFN GAMMA RESPONSE UP
MAHADEVAN RESPONSE TO MP470 UP
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
DAUER STAT3 TARGETS UP
LIANG SILENCED BY METHYLATION 2
NETPATH IL 3 PATHWAY UP
NAKAYAMA SOFT TISSUE TUMORS PCA1 UP
KEGG LEISHMANIA INFECTION
NETPATH IL 6 PATHWAY UPCXCL1, IRF1, MAP3K8
DER IFN ALPHA RESPONSE UP
MCLACHLAN DENTAL CARIES UP
NCI CD40 PATHWAY
NETPATH IL 5 PATHWAY UP
FOSTER INFLAMMATORY RESPONSE LPS DN
LEE LIVER CANCER E2F1 UP
MCLACHLAN DENTAL CARIES DN
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
HELLER SILENCED BY METHYLATION UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
ZHU CMV 8 HR UP
NCI IL23PATHWAYCXCL1
ZHOU INFLAMMATORY RESPONSE LPS UP
SMID BREAST CANCER LUMINAL B DN
SANA TNF SIGNALING UP
NCI IL27PATHWAY
FOSTER INFLAMMATORY RESPONSE LPS UP
CORUM REL-MAP3K8-RELA-TNIP2-PAPOLA COMPLEX
VERHAAK AML WITH NPM1 MUTATED UP
KEGG CHEMOKINE SIGNALING PATHWAY
GEISS RESPONSE TO DSRNA UP
KEGG CYTOSOLIC DNA SENSING PATHWAY
GRAHAM CML DIVIDING VS NORMAL QUIESCENT DN
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 1
BIOCARTA GRANULOCYTES PATHWAY
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX RPL6 RPL30 RPS13 CHUK DDX3X NFKB2 NFKBIB REL IKBKG NFKB1 MAP3K8 RELB GLG1 NFKBIA RELA TNIP2 GTF2I
ST TUMOR NECROSIS FACTOR PATHWAY
NCI IL12 2PATHWAY
ZHU CMV ALL UP
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
KEGG TOLL LIKE RECEPTOR SIGNALING PATHWAY
BERTUCCI MEDULLARY VS DUCTAL BREAST CANCER UP
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
yersinia enterocolitica wap bchelicobacter pylori kx1 mgeplactobacillus acidophilusbifidobacterium bifidumaeromonas caviaehrlichia chaffeensis wakullapseudomonas aeruginosa fdr440escherichia coliGeneSet Name
0.00010 0.02575 0.01173 0.07512 0.07215 0.00006 0.00843 0.00000NETPATH_IL_2_PATHWAY_UP
0.00001 0.02218 0.00000 0.00000 0.01697 0.00000 0.00195 0.00000KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.00000 0.03509 0.00008 0.00214 0.01924 0.00547 0.01700 0.00000GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00001 0.00013 0.01316 0.00572 0.07320 0.00000 0.04269 0.00028NETPATH_IL_9_PATHWAY_UP
0.00000 0.00517 0.00430 0.00474 0.16652 0.00447 0.00044 0.00000MAHAJAN_RESPONSE_TO_IL1A_UP
0.00000 0.02414 0.00000 0.00000 0.00000 0.00000 0.00068 0.00000ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP
0.00741 0.09639 0.01634 0.01762 0.13954 0.00014 0.02145 0.00015REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
0.00004 0.00000 0.00000 0.00000 0.00053 0.00000 0.00000 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00000 0.00015 0.00000 0.00005 0.00124 0.00000 0.00003 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00000 0.17667 0.00000 0.00167 0.00000 0.00000 0.15257 0.00004WALLACE_PROSTATE_CANCER_RACE_UP
0.00023 0.02539 0.00495 0.00296 0.12653 0.00059 0.00881 0.00002HORIUCHI_WTAP_TARGETS_UP
0.01379 0.17121 0.00048 0.02002 0.00000 0.00000 0.08331 0.00002WIELAND_UP_BY_HBV_INFECTION
0.00024 0.00002 0.00012 0.00103 0.01190 0.00000 0.00000 0.00000NETPATH_IL_4_PATHWAY_DOWN
0.00052 0.00294 0.06237 0.01764 0.16616 0.00004 0.00003 0.00000NETPATH_IL_7_PATHWAY_UP
0.00537 0.19498 0.00000 0.00005 0.00001 0.00001 0.00512 0.00000UROSEVIC_RESPONSE_TO_IMIQUIMOD
0.08946 0.04616 0.12322 0.08284 0.07318 0.00000 0.14730 0.00785NCI_IL6_7PATHWAY
0.00000 0.07388 0.00000 0.00000 0.00000 0.00000 0.00002 0.00000BROWNE_INTERFERON_RESPONSIVE_GENES
0.00277 0.09614 0.00000 0.00000 0.00316 0.00097 0.15521 0.00009KEGG_JAK_STAT_SIGNALING_PATHWAY
0.00012 0.10179 0.00372 0.00139 0.16527 0.00001 0.11741 0.00220TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP
0.00563 0.04581 0.00144 0.02261 0.00003 0.00214 0.00222 0.00000DER_IFN_BETA_RESPONSE_UP
0.00000 0.00002 0.00000 0.00013 0.06206 0.00001 0.00000 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00001 0.07713 0.00000 0.00000 0.00000 0.00000 0.01820 0.00000MARKEY_RB1_ACUTE_LOF_UP
0.00000 0.00077 0.00000 0.00006 0.00110 0.00000 0.00000 0.00000BASSO_CD40_SIGNALING_UP
0.00001 0.00011 0.00010 0.00012 0.00169 0.00027 0.02994 0.00037SOUCEK_MYC_TARGETS
0.00008 0.01257 0.00089 0.00779 0.07444 0.00144 0.00021 0.00000NUYTTEN_EZH2_TARGETS_UP
0.00003 0.00000 0.00233 0.00215 0.05340 0.00000 0.00513 0.00000DUTTA_APOPTOSIS_VIA_NFKB
0.00000 0.00157 0.00007 0.00294 0.00564 0.00000 0.00002 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.00850 0.03795 0.00091 0.00551 0.00005 0.00650 0.00011 0.00000DER_IFN_GAMMA_RESPONSE_UP
0.00006 0.00002 0.00272 0.00318 0.00240 0.00001 0.00002 0.00000MAHADEVAN_RESPONSE_TO_MP470_UP
0.00000 0.00018 0.00017 0.00006 0.00008 0.00000 0.00009 0.00000REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
0.06147 0.00067 0.00259 0.00011 0.05120 0.00307 0.00085 0.00003DAUER_STAT3_TARGETS_UP
0.00007 0.00031 0.00000 0.00000 0.00001 0.00000 0.00005 0.00000LIANG_SILENCED_BY_METHYLATION_2
0.00000 0.03326 0.00372 0.01084 0.00216 0.00000 0.15088 0.00000NETPATH_IL_3_PATHWAY_UP
0.10223 0.02466 0.01636 0.13644 0.00001 0.00000 0.05763 0.04537NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP
0.00695 0.00031 0.00174 0.00573 0.05933 0.00000 0.00027 0.00028KEGG_LEISHMANIA_INFECTION
0.00000 0.00236 0.00006 0.00007 0.10211 0.00000 0.03716 0.00000NETPATH_IL_6_PATHWAY_UP
0.01898 0.14451 0.00000 0.00081 0.00000 0.00122 0.00312 0.00000DER_IFN_ALPHA_RESPONSE_UP
0.00000 0.00018 0.00667 0.00155 0.00003 0.00000 0.00001 0.00000MCLACHLAN_DENTAL_CARIES_UP
0.03530 0.00012 0.02747 0.01529 0.06428 0.00163 0.00530 0.00010NCI_CD40_PATHWAY
0.00001 0.00021 0.01533 0.11144 0.07327 0.00000 0.00726 0.00001NETPATH_IL_5_PATHWAY_UP
0.00000 0.00006 0.00000 0.00000 0.00001 0.00000 0.00037 0.00000FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.00205 0.17072 0.00852 0.00724 0.01675 0.00000 0.16834 0.00843LEE_LIVER_CANCER_E2F1_UP
0.00001 0.00030 0.01242 0.00444 0.00003 0.00000 0.00017 0.00002MCLACHLAN_DENTAL_CARIES_DN
0.00000 0.00000 0.00000 0.00000 0.00002 0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00002 0.00000 0.00007 0.00001 0.00000 0.00002 0.00000GAURNIER_PSMD4_TARGETS
0.00040 0.02029 0.00489 0.02743 0.00206 0.00000 0.01964 0.00002HELLER_SILENCED_BY_METHYLATION_UP
0.00000 0.00000 0.00000 0.00000 0.00001 0.00000 0.00000 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00004 0.01261 0.00000 0.00006 0.00058 0.00000 0.06119 0.00000ZHU_CMV_8_HR_UP
0.00001 0.00589 0.00000 0.00000 0.00704 0.00020 0.01471 0.00000NCI_IL23PATHWAY
0.00000 0.00307 0.00000 0.00000 0.01590 0.00012 0.00027 0.00000ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.00824 0.17326 0.07352 0.13028 0.08643 0.00000 0.00710 0.00006SMID_BREAST_CANCER_LUMINAL_B_DN
0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000SANA_TNF_SIGNALING_UP
0.00720 0.10038 0.00000 0.00000 0.00317 0.00004 0.10440 0.00000NCI_IL27PATHWAY
0.00000 0.00587 0.00000 0.00000 0.01920 0.00000 0.09494 0.00011FOSTER_INFLAMMATORY_RESPONSE_LPS_UP
0.17454 0.12111 0.05982 0.02230 0.01112 0.16009 0.16848 0.01415CORUM_REL-MAP3K8-RELA-TNIP2-PAPOLA_COMPLEX
0.00000 0.00063 0.03043 0.02011 0.08932 0.00000 0.00218 0.00000VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.00276 0.12202 0.03796 0.10844 0.01801 0.00000 0.03885 0.00217KEGG_CHEMOKINE_SIGNALING_PATHWAY
0.00000 0.00000 0.00027 0.00426 0.00364 0.00022 0.00007 0.00000GEISS_RESPONSE_TO_DSRNA_UP
0.01094 0.03185 0.00033 0.00006 0.00700 0.00252 0.01678 0.00000KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY
0.00011 0.11276 0.00001 0.00145 0.00399 0.00030 0.03950 0.00000GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN
0.02956 0.15849 0.12179 0.14936 0.08380 0.00050 0.00499 0.00653SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1
0.00514 0.01647 0.01385 0.01849 0.04491 0.00012 0.02115 0.15379BIOCARTA_GRANULOCYTES_PATHWAY
0.17372 0.03787 0.03188 0.09338 0.14885 0.06742 0.00282 0.00003CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_RPL6_RPL30_RPS13_CHUK_DDX3X_NFKB2_NFKBIB_REL_IKBKG_NFKB1_MAP3K8_RELB_GLG1_NFKBIA_RELA_TNIP2__GTF2I
0.02172 0.00032 0.00006 0.00028 0.11624 0.00254 0.00001 0.00026ST_TUMOR_NECROSIS_FACTOR_PATHWAY
0.00156 0.05996 0.00000 0.00033 0.00545 0.00000 0.06732 0.00000NCI_IL12_2PATHWAY
0.00018 0.01293 0.00466 0.03180 0.14609 0.00083 0.02420 0.00000ZHU_CMV_ALL_UP
0.00000 0.00000 0.00000 0.00000 0.09323 0.00009 0.00000 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00177 0.01726 0.00000 0.00000 0.00443 0.00000 0.09337 0.00000KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.07837 0.01985 0.01593 0.11780 0.00108 0.00001 0.00131 0.00008BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP