BICLUSTER_ID : UPREG-154
PATHOGENS /5/ : pseudomonas aeruginosa,brucella neotomae,yersinia enterocolitica,shigella dysenteriae,ehrlichia chaffeensis
TARGETS /5/ : CYP1B1, IL1B, CCL2, TNF, PLAUR
Gene SetLeading Edge Genes
NETPATH IL 3 PATHWAY UPSOCS3, IL1B, CCL2, CCL4
NETPATH IL 5 PATHWAY UPLCP2, IL1B, CCL2, IER3
NETPATH IL 4 PATHWAY UPSOCS3, CYP1B1, CCL2
NETPATH IL 1 PATHWAY UPIL1B, CCL2, CXCL2, CCL4
NETPATH IL 9 PATHWAY UPSOCS3, CCL2
NETPATH IL 6 PATHWAY UPSOCS3, TNF
GERY CEBP TARGETSPLAUR
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
LEONARD HYPOXIA
CHEN LVAD SUPPORT OF FAILING HEART UP
LINDSTEDT DENDRITIC CELL MATURATION B
CROONQUIST STROMAL STIMULATION UP
SA MMP CYTOKINE CONNECTION
BIOCARTA IL1R PATHWAY
LINDSTEDT DENDRITIC CELL MATURATION A
KIM LRRC3B TARGETS
AMIT EGF RESPONSE 40 HELA
NETPATH IL 4 PATHWAY DOWN
NETPATH IL 7 PATHWAY UPCXCL2, CCL4
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
NETPATH KIT RECEPTOR PATHWAY UP
HARRIS HYPOXIA
LENAOUR DENDRITIC CELL MATURATION DN
HINATA NFKB TARGETS KERATINOCYTE UP
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
MUELLER METHYLATED IN GLIOBLASTOMA
BASSO CD40 SIGNALING UP
KAN RESPONSE TO ARSENIC TRIOXIDE
TIAN TNF SIGNALING NOT VIA NFKB
SOUCEK MYC TARGETS
NAGASHIMA NRG1 SIGNALING UP
DUTTA APOPTOSIS VIA NFKB
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 6HR DN
DIRMEIER LMP1 RESPONSE EARLY
MAHADEVAN RESPONSE TO MP470 UP
FERRARI RESPONSE TO FENRETINIDE UP
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
ZHOU INFLAMMATORY RESPONSE LIVE UP
AMIT EGF RESPONSE 120 HELA
DAUER STAT3 TARGETS UP
LIANG SILENCED BY METHYLATION 2
NIELSEN MALIGNAT FIBROUS HISTIOCYTOMA UP
MCLACHLAN DENTAL CARIES UP
ADDYA ERYTHROID DIFFERENTIATION BY HEMIN
DAZARD UV RESPONSE CLUSTER G2
CHEN HOXA5 TARGETS 9HR UP
FOSTER INFLAMMATORY RESPONSE LPS DN
MCLACHLAN DENTAL CARIES DN
AMIT SERUM RESPONSE 40 MCF10A
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
GRAHAM CML QUIESCENT VS CML DIVIDING UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
SATO SILENCED BY DEACETYLATION IN PANCREATIC CANCER
ZHOU INFLAMMATORY RESPONSE LPS UP
NCI IL23PATHWAY
SANA TNF SIGNALING UP
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
SESTO RESPONSE TO UV C3
VERHAAK AML WITH NPM1 MUTATED UP
GEISS RESPONSE TO DSRNA UP
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
HESS TARGETS OF HOXA9 AND MEIS1 DN
TIAN TNF SIGNALING VIA NFKB
NETPATH IL 2 PATHWAY UP
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
GOUYER TATI TARGETS UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
LEE LIVER CANCER HEPATOBLAST
ZUCCHI METASTASIS DN
NAGASHIMA EGF SIGNALING UP
PRAMOONJAGO SOX4 TARGETS UP
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
AMIT EGF RESPONSE 60 MCF10A
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
yersinia enterocolitica wap bcehrlichia chaffeensis arkansaehrlichia chaffeensis wakullapseudomonas aeruginosabrucella neotomaeshigella dysenteriaeehrlichia chaffeensis libertyGeneSet Name
0.00000 0.00000 0.00000 0.01596 0.00000 0.00147 0.00030NETPATH_IL_3_PATHWAY_UP
0.00001 0.00007 0.00000 0.00238 0.12369 0.00014 0.05924NETPATH_IL_5_PATHWAY_UP
0.00017 0.00011 0.00000 0.08967 0.10961 0.01729 0.02314NETPATH_IL_4_PATHWAY_UP
0.00001 0.00744 0.00022 0.00004 0.00114 0.00030 0.04640NETPATH_IL_1_PATHWAY_UP
0.00001 0.00097 0.00000 0.06627 0.00066 0.05058 0.00207NETPATH_IL_9_PATHWAY_UP
0.00000 0.00003 0.00000 0.01244 0.01660 0.00000 0.00150NETPATH_IL_6_PATHWAY_UP
0.00013 0.01308 0.00116 0.00843 0.18522 0.00067 0.05794GERY_CEBP_TARGETS
0.00000 0.00488 0.00301 0.00003 0.00128 0.00000 0.09755OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.00000 0.00021 0.00547 0.01558 0.03682 0.00252 0.01105GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00652 0.01232 0.00008 0.09020 0.16786 0.01701 0.02395LEONARD_HYPOXIA
0.00011 0.14628 0.01382 0.11056 0.12942 0.00017 0.02396CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP
0.00004 0.00007 0.00000 0.00005 0.02410 0.00053 0.02223LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00829 0.00000 0.00000 0.01456 0.00132 0.00808 0.00903CROONQUIST_STROMAL_STIMULATION_UP
0.00860 0.00037 0.00000 0.04053 0.10715 0.10485 0.00029SA_MMP_CYTOKINE_CONNECTION
0.00011 0.17481 0.01394 0.02041 0.07069 0.00825 0.06455BIOCARTA_IL1R_PATHWAY
0.00000 0.00000 0.00000 0.00387 0.00010 0.00034 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00014 0.00000 0.00017 0.03852 0.14453 0.07873 0.00144KIM_LRRC3B_TARGETS
0.00018 0.03874 0.00042 0.00000 0.01260 0.00000 0.15480AMIT_EGF_RESPONSE_40_HELA
0.00024 0.00001 0.00000 0.00000 0.00269 0.16501 0.00340NETPATH_IL_4_PATHWAY_DOWN
0.00052 0.00034 0.00004 0.00151 0.01290 0.04120 0.00005NETPATH_IL_7_PATHWAY_UP
0.00000 0.01384 0.00174 0.00381 0.01038 0.00000 0.01294THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.00004 0.02531 0.00015 0.05123 0.05217 0.00112 0.05936NETPATH_KIT_RECEPTOR_PATHWAY_UP
0.00004 0.00160 0.00025 0.00391 0.17495 0.00501 0.03906HARRIS_HYPOXIA
0.05709 0.00000 0.00000 0.02052 0.13798 0.02446 0.00000LENAOUR_DENDRITIC_CELL_MATURATION_DN
0.00000 0.00055 0.00001 0.00000 0.09086 0.00078 0.00058HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00000 0.00013 0.00000 0.00004 0.00378 0.00096 0.00966KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.09968 0.01499 0.00332 0.06034 0.16709 0.13134 0.02943MUELLER_METHYLATED_IN_GLIOBLASTOMA
0.00000 0.00000 0.00000 0.00006 0.03927 0.00004 0.00000BASSO_CD40_SIGNALING_UP
0.00286 0.09168 0.01034 0.00906 0.18328 0.02489 0.19460KAN_RESPONSE_TO_ARSENIC_TRIOXIDE
0.00034 0.09628 0.00264 0.05837 0.11317 0.00005 0.02313TIAN_TNF_SIGNALING_NOT_VIA_NFKB
0.00001 0.00003 0.00027 0.00251 0.01093 0.02047 0.00038SOUCEK_MYC_TARGETS
0.00000 0.00648 0.00000 0.00113 0.06679 0.00000 0.00351NAGASHIMA_NRG1_SIGNALING_UP
0.00003 0.00000 0.00000 0.00086 0.00644 0.02611 0.00023DUTTA_APOPTOSIS_VIA_NFKB
0.00000 0.17707 0.01086 0.00023 0.01515 0.11301 0.08988TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN
0.00000 0.00000 0.00000 0.00000 0.00214 0.00000 0.00342DIRMEIER_LMP1_RESPONSE_EARLY
0.00006 0.00029 0.00001 0.00009 0.09849 0.06328 0.00131MAHADEVAN_RESPONSE_TO_MP470_UP
0.00007 0.00947 0.00156 0.00003 0.02413 0.00712 0.18558FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.00000 0.00000 0.00000 0.00003 0.00575 0.17156 0.00023REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
0.00000 0.01092 0.00039 0.00000 0.01309 0.00006 0.05362ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.00000 0.07404 0.00037 0.00184 0.02726 0.00113 0.00639AMIT_EGF_RESPONSE_120_HELA
0.06147 0.01097 0.00307 0.00006 0.00155 0.00005 0.06350DAUER_STAT3_TARGETS_UP
0.00007 0.00001 0.00000 0.00126 0.01035 0.00396 0.00000LIANG_SILENCED_BY_METHYLATION_2
0.00012 0.01021 0.00276 0.00593 0.19381 0.13279 0.04791NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP
0.00000 0.00000 0.00000 0.00000 0.00479 0.01598 0.00000MCLACHLAN_DENTAL_CARIES_UP
0.00197 0.02809 0.03269 0.02053 0.09764 0.00827 0.02827ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN
0.00772 0.03944 0.00111 0.01158 0.00657 0.00032 0.05324DAZARD_UV_RESPONSE_CLUSTER_G2
0.00001 0.01709 0.00291 0.00776 0.02011 0.00000 0.02231CHEN_HOXA5_TARGETS_9HR_UP
0.00000 0.00000 0.00000 0.00185 0.00621 0.00236 0.00078FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.00001 0.00000 0.00000 0.00005 0.00595 0.02949 0.00000MCLACHLAN_DENTAL_CARIES_DN
0.00000 0.00705 0.00005 0.00028 0.03264 0.00000 0.03677AMIT_SERUM_RESPONSE_40_MCF10A
0.00000 0.00000 0.00000 0.00000 0.00041 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00000 0.00000 0.00036 0.00119 0.04466 0.00000GAURNIER_PSMD4_TARGETS
0.00008 0.00007 0.00003 0.00000 0.07552 0.00003 0.00022GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00000 0.00000 0.00000 0.00000 0.00387 0.00000 0.00059ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.03490 0.02810 0.04099 0.01071 0.03432 0.00666 0.09089SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER
0.00000 0.00269 0.00012 0.00043 0.02297 0.03754 0.03822ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.00001 0.00000 0.00020 0.00049 0.04130 0.09953 0.00440NCI_IL23PATHWAY
0.00000 0.00000 0.00000 0.00000 0.00058 0.00530 0.00008SANA_TNF_SIGNALING_UP
0.00000 0.00262 0.00004 0.00000 0.00059 0.00000 0.02652HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00406 0.17152 0.01412 0.00703 0.04591 0.00000 0.11456SESTO_RESPONSE_TO_UV_C3
0.00000 0.00000 0.00000 0.00267 0.03242 0.00095 0.00000VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.00000 0.00175 0.00022 0.00051 0.01183 0.01687 0.01274GEISS_RESPONSE_TO_DSRNA_UP
0.00000 0.02814 0.00336 0.00002 0.00256 0.00000 0.10221UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.00000 0.00000 0.00000 0.15886 0.15914 0.00054 0.00000HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN
0.00000 0.00003 0.00000 0.00000 0.05899 0.00005 0.02222TIAN_TNF_SIGNALING_VIA_NFKB
0.00010 0.00029 0.00006 0.11013 0.17779 0.08636 0.01786NETPATH_IL_2_PATHWAY_UP
0.00000 0.00001 0.00009 0.00000 0.00010 0.00000 0.00033GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00294 0.05925 0.06016 0.06637 0.03209 0.05947 0.06698GOUYER_TATI_TARGETS_UP
0.00000 0.00511 0.00265 0.00003 0.00123 0.00000 0.10357OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.00193 0.00021 0.00011 0.00093 0.17189 0.00154 0.02333LEE_LIVER_CANCER_HEPATOBLAST
0.00010 0.10538 0.00899 0.00002 0.01371 0.00013 0.05374ZUCCHI_METASTASIS_DN
0.00000 0.00040 0.00000 0.00102 0.01336 0.00000 0.01422NAGASHIMA_EGF_SIGNALING_UP
0.00024 0.07569 0.00099 0.00151 0.10655 0.00000 0.12936PRAMOONJAGO_SOX4_TARGETS_UP
0.00000 0.05114 0.00107 0.04258 0.16797 0.00000 0.01248PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.00000 0.02646 0.00070 0.00367 0.02489 0.00000 0.06686AMIT_EGF_RESPONSE_60_MCF10A