BICLUSTER_ID : UPREG-180
PATHOGENS /6/ : pseudomonas aeruginosa,listeria monocytogenes,lactobacillus acidophilus,streptococcus pyogenes,shigella dysenteriae,ehrlichia chaffeensis
TARGETS /3/ : IL1B, SAT1, TNFRSF1B
Gene SetLeading Edge Genes
NETPATH IL 2 PATHWAY UPIFIT1, KLF6, IL1B, DAXX, TNFRSF1B, TRIM21
GERY CEBP TARGETSGADD45B, JUNB, SAT1
RHEIN ALL GLUCOCORTICOID THERAPY UP
MISSIAGLIA REGULATED BY METHYLATION UP
BIOCARTA IL10 PATHWAY
BIOCARTA NFKB PATHWAY
MAHAJAN RESPONSE TO IL1A UP
KEGG ASTHMA
BOYAULT LIVER CANCER SUBCLASS G5 DN
LINDSTEDT DENDRITIC CELL MATURATION B
RASHI RESPONSE TO IONIZING RADIATION 2
LINDSTEDT DENDRITIC CELL MATURATION A
KIM LRRC3B TARGETS
NETPATH IL 4 PATHWAY DOWN
NETPATH IL 7 PATHWAY UP
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
NCI IL6 7PATHWAY
HARRIS HYPOXIA
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP
HINATA NFKB TARGETS KERATINOCYTE UP
MARKEY RB1 ACUTE LOF UP
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
BASSO CD40 SIGNALING UP
SOUCEK MYC TARGETS
MARZEC IL2 SIGNALING UP
NUYTTEN EZH2 TARGETS UP
DUTTA APOPTOSIS VIA NFKB
NCI PTP1BPATHWAY
TSAI RESPONSE TO IONIZING RADIATION
DIRMEIER LMP1 RESPONSE EARLY
NETPATH B CELL RECEPTOR PATHWAY UP
MAHADEVAN RESPONSE TO MP470 UP
BIOCARTA TID PATHWAY
DAUER STAT3 TARGETS UP
LIANG SILENCED BY METHYLATION 2
NETPATH IL 3 PATHWAY UP
KEGG LEISHMANIA INFECTION
NETPATH IL 6 PATHWAY UPGADD45B, JUNB, MAP3K8
MCLACHLAN DENTAL CARIES UP
NETPATH IL 5 PATHWAY UPPLSCR1, MYD88
FOSTER INFLAMMATORY RESPONSE LPS DN
MCLACHLAN DENTAL CARIES DN
TAVOR CEBPA TARGETS UP
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
GRAHAM CML QUIESCENT VS CML DIVIDING UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
NETPATH TNF ALPHA PATHWAY UP
ZHOU INFLAMMATORY RESPONSE LPS UP
NCI IL23PATHWAY
NOJIMA SFRP2 TARGETS DN
SANA TNF SIGNALING UP
AMIT SERUM RESPONSE 120 MCF10A
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
VERHAAK AML WITH NPM1 MUTATED UP
BROCKE APOPTOSIS REVERSED BY IL6
GEISS RESPONSE TO DSRNA UP
JISON SICKLE CELL DISEASE UP
DASU IL6 SIGNALING UP
TIAN TNF SIGNALING VIA NFKB
HUMMEL BURKITTS LYMPHOMA DN
NETPATH IL 1 PATHWAY UPCXCL1, CXCL2
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
ZUCCHI METASTASIS DN
PRAMOONJAGO SOX4 TARGETS UP
HUANG DASATINIB RESISTANCE UP
HINATA NFKB TARGETS FIBROBLAST UP
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
ehrlichia chaffeensis arkansaehrlichia chaffeensis wakullalactobacillus acidophiluspseudomonas aeruginosa fdr440listeria monocytogenesstreptococcus pyogenesshigella dysenteriaeGeneSet Name
0.00029 0.00006 0.01173 0.00843 0.00068 0.01602 0.08636NETPATH_IL_2_PATHWAY_UP
0.01308 0.00116 0.00427 0.00131 0.00163 0.01652 0.00067GERY_CEBP_TARGETS
0.00610 0.00170 0.09913 0.11161 0.00045 0.01655 0.04471RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP
0.00123 0.00006 0.00001 0.00000 0.00001 0.01557 0.00484MISSIAGLIA_REGULATED_BY_METHYLATION_UP
0.00082 0.00114 0.00000 0.01645 0.00014 0.03771 0.19139BIOCARTA_IL10_PATHWAY
0.06659 0.00699 0.01221 0.00100 0.08391 0.16684 0.01398BIOCARTA_NFKB_PATHWAY
0.01198 0.00447 0.00430 0.00044 0.00046 0.17839 0.00316MAHAJAN_RESPONSE_TO_IL1A_UP
0.06161 0.00288 0.00095 0.02296 0.00022 0.01985 0.19147KEGG_ASTHMA
0.00000 0.00000 0.02379 0.02290 0.00070 0.00000 0.02524BOYAULT_LIVER_CANCER_SUBCLASS_G5_DN
0.00007 0.00000 0.00000 0.00000 0.00437 0.02304 0.00053LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00307 0.00001 0.00034 0.00000 0.04054 0.00000 0.00004RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.00000 0.00000 0.00000 0.00003 0.00000 0.00032 0.00034LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00000 0.00017 0.00009 0.02984 0.00001 0.00000 0.07873KIM_LRRC3B_TARGETS
0.00001 0.00000 0.00012 0.00000 0.00001 0.00471 0.16501NETPATH_IL_4_PATHWAY_DOWN
0.00034 0.00004 0.06237 0.00003 0.09197 0.04416 0.04120NETPATH_IL_7_PATHWAY_UP
0.01384 0.00174 0.09352 0.00052 0.00000 0.11415 0.00000THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.00000 0.00000 0.12322 0.14730 0.03989 0.00000 0.00624NCI_IL6_7PATHWAY
0.00160 0.00025 0.18721 0.00003 0.00000 0.15102 0.00501HARRIS_HYPOXIA
0.00144 0.00056 0.00593 0.00448 0.00000 0.19929 0.00000DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP
0.00055 0.00001 0.00000 0.00000 0.00001 0.05930 0.00078HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00000 0.00000 0.00000 0.01820 0.00004 0.00000 0.14227MARKEY_RB1_ACUTE_LOF_UP
0.00013 0.00000 0.00000 0.00034 0.00736 0.02604 0.00096KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00000 0.00000 0.00000 0.00000 0.00020 0.00023 0.00004BASSO_CD40_SIGNALING_UP
0.00003 0.00027 0.00010 0.02994 0.09270 0.00021 0.02047SOUCEK_MYC_TARGETS
0.00161 0.00004 0.15147 0.01502 0.00507 0.13526 0.00321MARZEC_IL2_SIGNALING_UP
0.00475 0.00144 0.00089 0.00021 0.00000 0.10005 0.08521NUYTTEN_EZH2_TARGETS_UP
0.00000 0.00000 0.00233 0.00513 0.01422 0.02575 0.02611DUTTA_APOPTOSIS_VIA_NFKB
0.09080 0.03537 0.01551 0.11264 0.07255 0.10487 0.09041NCI_PTP1BPATHWAY
0.00169 0.00000 0.18848 0.04793 0.13958 0.02653 0.00016TSAI_RESPONSE_TO_IONIZING_RADIATION
0.00000 0.00000 0.00007 0.00002 0.00199 0.00616 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.01457 0.00122 0.17292 0.17531 0.03363 0.08745 0.09708NETPATH_B_CELL_RECEPTOR_PATHWAY_UP
0.00029 0.00001 0.00272 0.00002 0.00004 0.01593 0.06328MAHADEVAN_RESPONSE_TO_MP470_UP
0.01590 0.00829 0.09391 0.00010 0.07253 0.02287 0.02606BIOCARTA_TID_PATHWAY
0.01097 0.00307 0.00259 0.00085 0.00016 0.00038 0.00005DAUER_STAT3_TARGETS_UP
0.00001 0.00000 0.00000 0.00005 0.00001 0.00099 0.00396LIANG_SILENCED_BY_METHYLATION_2
0.00000 0.00000 0.00372 0.15088 0.00553 0.00095 0.00147NETPATH_IL_3_PATHWAY_UP
0.00000 0.00000 0.00174 0.00027 0.00055 0.00061 0.00317KEGG_LEISHMANIA_INFECTION
0.00003 0.00000 0.00006 0.03716 0.00233 0.00001 0.00000NETPATH_IL_6_PATHWAY_UP
0.00000 0.00000 0.00667 0.00001 0.00000 0.00000 0.01598MCLACHLAN_DENTAL_CARIES_UP
0.00007 0.00000 0.01533 0.00726 0.00007 0.03974 0.00014NETPATH_IL_5_PATHWAY_UP
0.00000 0.00000 0.00000 0.00037 0.00001 0.00568 0.00236FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.00000 0.00000 0.01242 0.00017 0.00000 0.00000 0.02949MCLACHLAN_DENTAL_CARIES_DN
0.00572 0.00085 0.10298 0.08516 0.00125 0.00445 0.00349TAVOR_CEBPA_TARGETS_UP
0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00000 0.00000 0.00002 0.00001 0.00000 0.04466GAURNIER_PSMD4_TARGETS
0.00007 0.00003 0.00000 0.00002 0.00097 0.05533 0.00003GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00000 0.00000 0.00000 0.00000 0.00000 0.00019 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.04059 0.11655 0.09704 0.00318 0.00123 0.03392 0.07626NETPATH_TNF_ALPHA_PATHWAY_UP
0.00269 0.00012 0.00000 0.00027 0.00000 0.06782 0.03754ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00020 0.00000 0.01471 0.00100 0.00014 0.09953NCI_IL23PATHWAY
0.00573 0.00758 0.00035 0.16491 0.02237 0.01391 0.19222NOJIMA_SFRP2_TARGETS_DN
0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00530SANA_TNF_SIGNALING_UP
0.04018 0.00009 0.01424 0.02960 0.00040 0.09332 0.00021AMIT_SERUM_RESPONSE_120_MCF10A
0.00262 0.00004 0.11701 0.00011 0.00000 0.09492 0.00000HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00000 0.00000 0.03043 0.00218 0.00000 0.01128 0.00095VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.00000 0.00000 0.03083 0.04896 0.00001 0.00074 0.00055BROCKE_APOPTOSIS_REVERSED_BY_IL6
0.00175 0.00022 0.00027 0.00007 0.00027 0.01876 0.01687GEISS_RESPONSE_TO_DSRNA_UP
0.00000 0.00000 0.00011 0.19067 0.00000 0.00066 0.07115JISON_SICKLE_CELL_DISEASE_UP
0.14492 0.03956 0.15237 0.00711 0.00595 0.04449 0.00099DASU_IL6_SIGNALING_UP
0.00003 0.00000 0.00000 0.00000 0.00054 0.00455 0.00005TIAN_TNF_SIGNALING_VIA_NFKB
0.00212 0.00020 0.02581 0.01003 0.17259 0.02106 0.03331HUMMEL_BURKITTS_LYMPHOMA_DN
0.00744 0.00022 0.00114 0.00000 0.00000 0.03192 0.00030NETPATH_IL_1_PATHWAY_UP
0.00001 0.00009 0.00000 0.00000 0.00001 0.05507 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.10538 0.00899 0.04132 0.00002 0.00518 0.01684 0.00013ZUCCHI_METASTASIS_DN
0.07569 0.00099 0.00031 0.00044 0.01526 0.19931 0.00000PRAMOONJAGO_SOX4_TARGETS_UP
0.00143 0.00093 0.17300 0.09974 0.07424 0.04595 0.16166HUANG_DASATINIB_RESISTANCE_UP
0.00358 0.00151 0.01167 0.00000 0.00031 0.14412 0.00153HINATA_NFKB_TARGETS_FIBROBLAST_UP