BICLUSTER_ID : UPREG-196
PATHOGENS /4/ : pseudomonas aeruginosa,streptococcus pneumoniae,yersinia enterocolitica,brucella ovis
TARGETS /3/ : IL6, PTGS2, PLAUR
Gene SetLeading Edge Genes
NETPATH EGFR1 PATHWAY UPPTGS2, PHLDA1, PLK2, PLAUR
NETPATH IL 2 PATHWAY UPETS2, IL6, PLAUR
NETPATH IL 1 PATHWAY UPIL6, PTGS2, CXCL2
NETPATH IL 4 PATHWAY DOWNGADD45B, PTGS2, CXCL2
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
NETPATH IL 9 PATHWAY UPJUNB
MAHAJAN RESPONSE TO IL1A UP
DORN ADENOVIRUS INFECTION 32HR DN
LINDSTEDT DENDRITIC CELL MATURATION B
CROONQUIST STROMAL STIMULATION UP
LINDSTEDT DENDRITIC CELL MATURATION A
SIMBULAN UV RESPONSE NORMAL UP
NETPATH IL 7 PATHWAY UPCXCL2
DORN ADENOVIRUS INFECTION 12HR UP
MAHADEVAN RESPONSE TO MP470 DN
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION ERYTHROCYTE UP
NETPATH KIT RECEPTOR PATHWAY UP
HINATA NFKB TARGETS KERATINOCYTE UP
SEIKE LUNG CANCER POOR SURVIVAL
DORN ADENOVIRUS INFECTION 48HR DN
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
BASSO CD40 SIGNALING UP
OSADA ASCL1 TARGETS DN
SOUCEK MYC TARGETS
MARZEC IL2 SIGNALING UP
AMIT SERUM RESPONSE 60 MCF10A
DUTTA APOPTOSIS VIA NFKB
DIRMEIER LMP1 RESPONSE EARLY
FERRARI RESPONSE TO FENRETINIDE UP
BILD HRAS ONCOGENIC SIGNATURE
ZHOU INFLAMMATORY RESPONSE LIVE UP
ONDER CDH1 TARGETS 3 DN
AMIT EGF RESPONSE 120 HELA
DAUER STAT3 TARGETS UP
LIANG SILENCED BY METHYLATION 2
NETPATH IL 3 PATHWAY UP
NETPATH IL 6 PATHWAY UPGADD45B, ID2, JUNB
DAZARD RESPONSE TO UV NHEK UP
MCLACHLAN DENTAL CARIES UP
BERENJENO TRANSFORMED BY RHOA FOREVER DN
DAZARD UV RESPONSE CLUSTER G2
WANG RECURRENT LIVER CANCER DN
NETPATH IL 5 PATHWAY UP
FOSTER INFLAMMATORY RESPONSE LPS DN
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
GRAHAM CML QUIESCENT VS CML DIVIDING UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
ZHOU INFLAMMATORY RESPONSE LPS UP
AMIT SERUM RESPONSE 120 MCF10A
AMIT EGF RESPONSE 240 HELA
ONDER CDH1 TARGETS 2 DN
DORN ADENOVIRUS INFECTION 24HR DN
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
SESTO RESPONSE TO UV C3
VERHAAK AML WITH NPM1 MUTATED UP
KIM WT1 TARGETS UP
GEISS RESPONSE TO DSRNA UP
ONDER CDH1 TARGETS 1 DN
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
ST TUMOR NECROSIS FACTOR PATHWAY
ZHOU INFLAMMATORY RESPONSE FIMA UP
DASU IL6 SIGNALING UP
TIAN TNF SIGNALING VIA NFKB
AMIT EGF RESPONSE 120 MCF10A
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
LEE LIVER CANCER HEPATOBLAST
ZUCCHI METASTASIS DN
NAGASHIMA EGF SIGNALING UP
AMIT EGF RESPONSE 60 MCF10A
HINATA NFKB TARGETS FIBROBLAST UP
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
yersinia enterocolitica wap bl6yersinia enterocolitica wap bcyersinia enterocolitica p60 bcpseudomonas aeruginosa fdr440brucella ovisstreptococcus pneumoniae tigr4GeneSet Name
0.04029 0.00014 0.00205 0.00005 0.19976 0.00000NETPATH_EGFR1_PATHWAY_UP
0.01769 0.00010 0.00018 0.00843 0.18663 0.07061NETPATH_IL_2_PATHWAY_UP
0.00024 0.00001 0.00001 0.00000 0.01452 0.00001NETPATH_IL_1_PATHWAY_UP
0.00145 0.00024 0.00040 0.00000 0.00062 0.01938NETPATH_IL_4_PATHWAY_DOWN
0.00000 0.00000 0.00000 0.00010 0.01964 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.00000 0.00000 0.00000 0.01700 0.07308 0.00058GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00016 0.00001 0.00009 0.04269 0.00706 0.05141NETPATH_IL_9_PATHWAY_UP
0.00113 0.00000 0.00009 0.00044 0.08148 0.00006MAHAJAN_RESPONSE_TO_IL1A_UP
0.13670 0.01879 0.00471 0.00021 0.03181 0.00000DORN_ADENOVIRUS_INFECTION_32HR_DN
0.04571 0.00004 0.00237 0.00000 0.02851 0.00796LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.04761 0.00829 0.01017 0.00017 0.01979 0.00000CROONQUIST_STROMAL_STIMULATION_UP
0.00011 0.00000 0.00000 0.00003 0.00044 0.15403LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.11226 0.00821 0.04892 0.01311 0.05634 0.00048SIMBULAN_UV_RESPONSE_NORMAL_UP
0.00623 0.00052 0.00028 0.00003 0.01316 0.00009NETPATH_IL_7_PATHWAY_UP
0.00709 0.01175 0.00041 0.04477 0.03636 0.00004DORN_ADENOVIRUS_INFECTION_12HR_UP
0.00031 0.00006 0.00009 0.02760 0.06080 0.00000MAHADEVAN_RESPONSE_TO_MP470_DN
0.00024 0.00000 0.00000 0.00052 0.06140 0.00077THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.01109 0.00012 0.00004 0.11741 0.18029 0.07760TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP
0.00062 0.00004 0.00570 0.18259 0.17580 0.00001NETPATH_KIT_RECEPTOR_PATHWAY_UP
0.00000 0.00000 0.00000 0.00000 0.03817 0.00741HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00425 0.00572 0.01385 0.00573 0.05722 0.05865SEIKE_LUNG_CANCER_POOR_SURVIVAL
0.19614 0.01624 0.00630 0.00037 0.09920 0.00001DORN_ADENOVIRUS_INFECTION_48HR_DN
0.00045 0.00000 0.00008 0.00034 0.05857 0.02561KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00000 0.00000 0.00003 0.00000 0.08843 0.01887BASSO_CD40_SIGNALING_UP
0.08327 0.08630 0.06140 0.11392 0.17587 0.09859OSADA_ASCL1_TARGETS_DN
0.00000 0.00001 0.00008 0.02994 0.00716 0.02991SOUCEK_MYC_TARGETS
0.00016 0.00006 0.00008 0.01502 0.05261 0.01084MARZEC_IL2_SIGNALING_UP
0.00000 0.00000 0.00000 0.01060 0.11740 0.00000AMIT_SERUM_RESPONSE_60_MCF10A
0.00646 0.00003 0.00013 0.00513 0.01264 0.00090DUTTA_APOPTOSIS_VIA_NFKB
0.00000 0.00000 0.00000 0.00002 0.01330 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.00508 0.00007 0.00050 0.00002 0.08101 0.00024FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.00208 0.00000 0.00000 0.00028 0.06372 0.00000BILD_HRAS_ONCOGENIC_SIGNATURE
0.00000 0.00000 0.00000 0.00010 0.00746 0.00172ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.00150 0.01083 0.00099 0.00194 0.00115 0.00000ONDER_CDH1_TARGETS_3_DN
0.00077 0.00000 0.00004 0.00068 0.12378 0.00000AMIT_EGF_RESPONSE_120_HELA
0.05660 0.06147 0.02597 0.00085 0.10980 0.00000DAUER_STAT3_TARGETS_UP
0.00000 0.00007 0.00000 0.00005 0.03860 0.13850LIANG_SILENCED_BY_METHYLATION_2
0.00000 0.00000 0.00000 0.15088 0.00156 0.00810NETPATH_IL_3_PATHWAY_UP
0.00000 0.00000 0.00000 0.03716 0.01065 0.00000NETPATH_IL_6_PATHWAY_UP
0.08717 0.00323 0.01065 0.10778 0.12521 0.00000DAZARD_RESPONSE_TO_UV_NHEK_UP
0.00049 0.00000 0.00008 0.00001 0.03202 0.18322MCLACHLAN_DENTAL_CARIES_UP
0.19546 0.00000 0.00060 0.11486 0.17996 0.00046BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN
0.11521 0.00772 0.01385 0.00228 0.14937 0.00000DAZARD_UV_RESPONSE_CLUSTER_G2
0.11334 0.00893 0.02120 0.10298 0.13576 0.01420WANG_RECURRENT_LIVER_CANCER_DN
0.02712 0.00001 0.00159 0.00726 0.03173 0.00002NETPATH_IL_5_PATHWAY_UP
0.00000 0.00000 0.00000 0.00037 0.01159 0.01424FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.00000 0.00000 0.00000 0.00000 0.00076 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00000 0.00000 0.00002 0.00581 0.09452GAURNIER_PSMD4_TARGETS
0.00810 0.00008 0.00030 0.00002 0.05672 0.00000GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00000 0.00000 0.00000 0.00000 0.00055 0.00001ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00000 0.00000 0.00000 0.00027 0.04278 0.05005ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.00013 0.00000 0.00000 0.02960 0.01293 0.00000AMIT_SERUM_RESPONSE_120_MCF10A
0.01085 0.00000 0.00048 0.01646 0.06176 0.15294AMIT_EGF_RESPONSE_240_HELA
0.00065 0.00111 0.00011 0.00005 0.13624 0.10479ONDER_CDH1_TARGETS_2_DN
0.09507 0.00323 0.00217 0.00130 0.12363 0.00000DORN_ADENOVIRUS_INFECTION_24HR_DN
0.00080 0.00000 0.00006 0.00011 0.00038 0.00000HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00757 0.00406 0.00270 0.02538 0.12374 0.00000SESTO_RESPONSE_TO_UV_C3
0.00001 0.00000 0.00000 0.00218 0.08159 0.01022VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.01612 0.00000 0.00000 0.00002 0.09311 0.00001KIM_WT1_TARGETS_UP
0.00179 0.00000 0.00000 0.00007 0.08028 0.03793GEISS_RESPONSE_TO_DSRNA_UP
0.07697 0.00277 0.01007 0.00709 0.11964 0.00114ONDER_CDH1_TARGETS_1_DN
0.00000 0.00000 0.00000 0.02749 0.01384 0.00000UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.16103 0.02172 0.13679 0.00001 0.06146 0.10060ST_TUMOR_NECROSIS_FACTOR_PATHWAY
0.00018 0.00001 0.00000 0.00013 0.01646 0.02569ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP
0.01073 0.00001 0.00020 0.00711 0.14484 0.00007DASU_IL6_SIGNALING_UP
0.00000 0.00000 0.00000 0.00000 0.02617 0.00001TIAN_TNF_SIGNALING_VIA_NFKB
0.02376 0.00001 0.00028 0.00020 0.12289 0.00000AMIT_EGF_RESPONSE_120_MCF10A
0.00024 0.00000 0.00000 0.00000 0.00040 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00000 0.00000 0.00000 0.00011 0.01906 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.00139 0.00193 0.00168 0.00243 0.15857 0.01752LEE_LIVER_CANCER_HEPATOBLAST
0.08451 0.00010 0.05022 0.00002 0.10002 0.00000ZUCCHI_METASTASIS_DN
0.00000 0.00000 0.00000 0.00002 0.19801 0.00000NAGASHIMA_EGF_SIGNALING_UP
0.00000 0.00000 0.00000 0.00027 0.03197 0.00000AMIT_EGF_RESPONSE_60_MCF10A
0.03435 0.00001 0.00008 0.00000 0.16302 0.00038HINATA_NFKB_TARGETS_FIBROBLAST_UP