BICLUSTER_ID : UPREG-2
PATHOGENS /5/ : listeria monocytogenes,escherichia coli,yersinia enterocolitica,mycobacterium tuberculosis,ehrlichia chaffeensis
TARGETS /5/ : IL6, JAK2, IL1R1, TNF, PLAUR
Gene SetLeading Edge Genes
NETPATH IL 2 PATHWAY UPIFIT1, KLF6, GADD45G, TRIM21, PMAIP1, LCP2, IL6, UPP1, IL1R1, PLAUR, CCL4, MX1, TNF
NCI IL23PATHWAYIL6, CXCL1, JAK2, TNF
NETPATH IL 4 PATHWAY UPIL1RN, IL6, RIPK2, UPP1
GERY CEBP TARGETSATF3, GADD45B, CXCL1, JUNB, GADD45G, PLAUR
NETPATH IL 1 PATHWAY UPIL6, CXCL1, CXCL2, CCL4
NETPATH IL 6 PATHWAY UPMAFF, GADD45B, CXCL1, JUNB, MAP3K8, MX1, TNF
BIOCARTA IL10 PATHWAY
LI CISPLATIN RESISTANCE DN
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
BIOCARTA NFKB PATHWAY
MAHAJAN RESPONSE TO IL1A UP
WEINMANN ADAPTATION TO HYPOXIA DN
LINDGREN BLADDER CANCER CLUSTER 2B
KEGG GRAFT VERSUS HOST DISEASE
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 16D UP
ICHIBA GRAFT VERSUS HOST DISEASE D7 UP
CHEN LVAD SUPPORT OF FAILING HEART UP
TENEDINI MEGAKARYOCYTE MARKERS
LINDSTEDT DENDRITIC CELL MATURATION B
BIOCARTA IL1R PATHWAY
KRASNOSELSKAYA ILF3 TARGETS UP
RASHI RESPONSE TO IONIZING RADIATION 2
LINDSTEDT DENDRITIC CELL MATURATION A
RADAEVA RESPONSE TO IFNA1 UP
LIEN BREAST CARCINOMA METAPLASTIC VS DUCTAL UP
ELVIDGE HYPOXIA UP
AMIT EGF RESPONSE 40 HELA
BOWIE RESPONSE TO EXTRACELLULAR MATRIX
NETPATH IL 7 PATHWAY UP
BROWNE INTERFERON RESPONSIVE GENES
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION ERYTHROCYTE UP
ROETH TERT TARGETS UP
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION SUSTAINDED IN ERYTHROCYTE UP
HINATA NFKB TARGETS KERATINOCYTE UP
MARKEY RB1 ACUTE LOF UP
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
XU AKT1 TARGETS 6HR
OSADA ASCL1 TARGETS DN
VART KSHV INFECTION ANGIOGENIC MARKERS UP
NUYTTEN EZH2 TARGETS UP
DUTTA APOPTOSIS VIA NFKB
POOLA INVASIVE BREAST CANCER UP
DIRMEIER LMP1 RESPONSE EARLY
RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY DN
LIU VAV3 PROSTATE CARCINOGENESIS UP
SEITZ NEOPLASTIC TRANSFORMATION BY 8P DELETION UP
BENNETT SYSTEMIC LUPUS ERYTHEMATOSUS
NCI NFAT TFPATHWAY
ZHOU INFLAMMATORY RESPONSE LIVE UP
RUTELLA RESPONSE TO HGF VS CSF2RB AND IL4 UP
ONDER CDH1 TARGETS 3 DN
AMIT EGF RESPONSE 120 HELA
NAKAYAMA SOFT TISSUE TUMORS PCA1 UP
HELLEBREKERS SILENCED DURING TUMOR ANGIOGENESIS
NIELSEN MALIGNAT FIBROUS HISTIOCYTOMA UP
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS UP
WINTER HYPOXIA METAGENE
MCLACHLAN DENTAL CARIES UP
GAJATE RESPONSE TO TRABECTEDIN UP
NEWMAN ERCC6 TARGETS UP
PODAR RESPONSE TO ADAPHOSTIN UP
FOSTER INFLAMMATORY RESPONSE LPS DN
LEE LIVER CANCER E2F1 UP
TAVOR CEBPA TARGETS UP
GAURNIER PSMD4 TARGETS
HELLER SILENCED BY METHYLATION UP
GRANDVAUX IFN RESPONSE NOT VIA IRF3
FARMER BREAST CANCER CLUSTER 1
BOWIE RESPONSE TO TAMOXIFEN
SATO SILENCED BY DEACETYLATION IN PANCREATIC CANCER
GOZGIT ESR1 TARGETS DN
MARKEY RB1 CHRONIC LOF DN
ICHIBA GRAFT VERSUS HOST DISEASE 35D UP
NCI AMB2 NEUTROPHILS PATHWAY
SMID BREAST CANCER LUMINAL B DN
ZHOU INFLAMMATORY RESPONSE LPS UP
GESERICK TERT TARGETS DN
NOJIMA SFRP2 TARGETS DN
NETPATH TGFBETA RECEPTOR PATHWAY DOWN
AMIT SERUM RESPONSE 120 MCF10A
BROWNE HCMV INFECTION 2HR UP
LEE LIVER CANCER MYC E2F1 UP
SESTO RESPONSE TO UV C3
VERHAAK AML WITH NPM1 MUTATED UP
BROCKE APOPTOSIS REVERSED BY IL6
GEISS RESPONSE TO DSRNA UP
GRAHAM CML DIVIDING VS NORMAL QUIESCENT DN
NCI P53DOWNSTREAMPATHWAY
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 1
NCI IL12 2PATHWAY
ZHOU INFLAMMATORY RESPONSE FIMA UP
TIAN TNF SIGNALING VIA NFKB
ZHU CMV ALL UP
KEGG TOLL LIKE RECEPTOR SIGNALING PATHWAY
OKUMURA INFLAMMATORY RESPONSE LPS
LEE LIVER CANCER HEPATOBLAST
NAGASHIMA EGF SIGNALING UP
KEGG TYPE I DIABETES MELLITUS
HUANG DASATINIB RESISTANCE UP
AMIT EGF RESPONSE 60 MCF10A
HINATA NFKB TARGETS FIBROBLAST UP
NOJIMA SFRP2 TARGETS UP
CHARAFE BREAST CANCER LUMINAL VS BASAL DN
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
CHEN HOXA5 TARGETS 6HR UP
MISSIAGLIA REGULATED BY METHYLATION UP
SMIRNOV CIRCULATING ENDOTHELIOCYTES IN CANCER UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
CHEN LVAD SUPPORT OF FAILING HEART DN
ZHANG INTERFERON RESPONSE
CHANG IMMORTALIZED BY HPV31 DN
CROONQUIST STROMAL STIMULATION UP
LEE LIVER CANCER MYC TGFA UP
SA MMP CYTOKINE CONNECTION
HALMOS CEBPA TARGETS UP
WU CELL MIGRATION
WALLACE PROSTATE CANCER RACE UP
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 10D UP
KIM LRRC3B TARGETS
HORIUCHI WTAP TARGETS UP
NETPATH IL 4 PATHWAY DOWNGADD45B, CXCL2, MX1, GBP2
GUTIERREZ WALDENSTROEMS MACROGLOBULINEMIA 1 DN
MAHADEVAN RESPONSE TO MP470 DN
UROSEVIC RESPONSE TO IMIQUIMOD
RIGGI EWING SARCOMA PROGENITOR UP
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 3D UP
HARRIS HYPOXIA
NETPATH KIT RECEPTOR PATHWAY UP
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS DN
DER IFN BETA RESPONSE UP
TSAI DNAJB4 TARGETS UP
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 10D DN
KAN RESPONSE TO ARSENIC TRIOXIDE
BASSO CD40 SIGNALING UP
TIAN TNF SIGNALING NOT VIA NFKB
NAGASHIMA NRG1 SIGNALING UP
MARZEC IL2 SIGNALING UP
SOUCEK MYC TARGETS
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 6HR DN
BOYLAN MULTIPLE MYELOMA C D DN
ZERBINI RESPONSE TO SULINDAC UP
BILBAN B CLL LPL DN
WANG ESOPHAGUS CANCER VS NORMAL UP
CROMER TUMORIGENESIS UP
MAHADEVAN RESPONSE TO MP470 UP
ZHAN MULTIPLE MYELOMA LB DN
KEGG AUTOIMMUNE THYROID DISEASE
FERRARI RESPONSE TO FENRETINIDE UP
BILD HRAS ONCOGENIC SIGNATURE
SANA RESPONSE TO IFNG UP
LIANG SILENCED BY METHYLATION 2
DAUER STAT3 TARGETS UP
NETPATH IL 3 PATHWAY UPCCL4
ZHANG ANTIVIRAL RESPONSE TO RIBAVIRIN DN
KEGG LEISHMANIA INFECTION
DER IFN ALPHA RESPONSE UP
AMIT EGF RESPONSE 60 HELA
ADDYA ERYTHROID DIFFERENTIATION BY HEMIN
BERENJENO TRANSFORMED BY RHOA FOREVER DN
CHEN HOXA5 TARGETS 9HR UP
DAZARD UV RESPONSE CLUSTER G2
EINAV INTERFERON SIGNATURE IN CANCER
NETPATH IL 5 PATHWAY UPPLSCR1, UPP1, CASP4
MCLACHLAN DENTAL CARIES DN
KEGG ALLOGRAFT REJECTION
AMIT SERUM RESPONSE 40 MCF10A
SEKI INFLAMMATORY RESPONSE LPS UP
HELLER HDAC TARGETS SILENCED BY METHYLATION UP
GRAHAM CML QUIESCENT VS CML DIVIDING UP
CONCANNON APOPTOSIS BY EPOXOMICIN UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
ZHU CMV 8 HR UP
BIOCARTA INFLAM PATHWAY
SANA TNF SIGNALING UP
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 8D UP
NCI IL27PATHWAY
MOSERLE IFNA RESPONSE
SCHUETZ BREAST CANCER DUCTAL INVASIVE UP
SENESE HDAC1 AND HDAC2 TARGETS UP
FOSTER INFLAMMATORY RESPONSE LPS UP
BIOCARTA ASBCELL PATHWAY
XU HGF TARGETS INDUCED BY AKT1 6HR
ONDER CDH1 TARGETS 2 DN
SENESE HDAC1 TARGETS UP
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
KEGG HEMATOPOIETIC CELL LINEAGE
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 2
KIM WT1 TARGETS UP
SENESE HDAC3 TARGETS UP
KEGG CYTOSOLIC DNA SENSING PATHWAY
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
JISON SICKLE CELL DISEASE UP
HESS TARGETS OF HOXA9 AND MEIS1 DN
DASU IL6 SIGNALING UP
ELVIDGE HYPOXIA BY DMOG UP
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
ZUCCHI METASTASIS DN
LU IL4 SIGNALING
RUTELLA RESPONSE TO HGF UP
PRAMOONJAGO SOX4 TARGETS UP
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
LU TUMOR ENDOTHELIAL MARKERS UP
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
yersinia enterocolitica wap bl6yersinia enterocolitica wap bcyersinia enterocolitica p60 bl6yersinia enterocolitica p60 bclisteria monocytogenesehrlichia chaffeensis arkansaehrlichia chaffeensis wakullamycobacterium tuberculosisescherichia coliGeneSet Name
0.01769 0.00010 0.00994 0.00018 0.00068 0.00029 0.00006 0.00008 0.00000NETPATH_IL_2_PATHWAY_UP
0.00000 0.00001 0.00000 0.00000 0.00100 0.00000 0.00020 0.00126 0.00000NCI_IL23PATHWAY
0.00016 0.00017 0.00010 0.00000 0.00098 0.00011 0.00000 0.01106 0.00129NETPATH_IL_4_PATHWAY_UP
0.00277 0.00013 0.00040 0.00510 0.00163 0.01308 0.00116 0.00000 0.01389GERY_CEBP_TARGETS
0.00024 0.00001 0.00000 0.00001 0.00000 0.00744 0.00022 0.00602 0.00000NETPATH_IL_1_PATHWAY_UP
0.00000 0.00000 0.00000 0.00000 0.00233 0.00003 0.00000 0.00000 0.00000NETPATH_IL_6_PATHWAY_UP
0.00016 0.00059 0.00108 0.00003 0.00014 0.00082 0.00114 0.00336 0.00002BIOCARTA_IL10_PATHWAY
0.08466 0.09993 0.01771 0.01015 0.16854 0.17968 0.06248 0.07997 0.01079LI_CISPLATIN_RESISTANCE_DN
0.00000 0.00000 0.00021 0.00000 0.00023 0.00021 0.00547 0.00002 0.00000GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.11451 0.01359 0.05121 0.03120 0.08391 0.06659 0.00699 0.00073 0.00000BIOCARTA_NFKB_PATHWAY
0.00113 0.00000 0.00010 0.00009 0.00046 0.01198 0.00447 0.00132 0.00000MAHAJAN_RESPONSE_TO_IL1A_UP
0.00024 0.00001 0.00006 0.00000 0.01186 0.01089 0.04046 0.03354 0.00000WEINMANN_ADAPTATION_TO_HYPOXIA_DN
0.02833 0.00193 0.01562 0.00358 0.06578 0.00000 0.00000 0.00120 0.01415LINDGREN_BLADDER_CANCER_CLUSTER_2B
0.00424 0.00024 0.00069 0.00055 0.00003 0.00000 0.00000 0.02321 0.00002KEGG_GRAFT_VERSUS_HOST_DISEASE
0.00000 0.00282 0.00007 0.00000 0.00069 0.00000 0.00000 0.00000 0.00009TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP
0.00000 0.00000 0.00011 0.00000 0.00001 0.00000 0.00000 0.00000 0.00000ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP
0.02279 0.00011 0.00019 0.00041 0.06346 0.14628 0.01382 0.00015 0.00159CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP
0.05734 0.07725 0.04211 0.02423 0.09679 0.00000 0.00000 0.13556 0.00011TENEDINI_MEGAKARYOCYTE_MARKERS
0.04571 0.00004 0.04591 0.00237 0.00437 0.00007 0.00000 0.00000 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00017 0.00011 0.00114 0.00008 0.00776 0.17481 0.01394 0.00118 0.00000BIOCARTA_IL1R_PATHWAY
0.00249 0.02335 0.00309 0.00020 0.00001 0.00016 0.00014 0.00000 0.00000KRASNOSELSKAYA_ILF3_TARGETS_UP
0.00427 0.00001 0.00297 0.00008 0.04054 0.00307 0.00001 0.00000 0.00000RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.00011 0.00000 0.00029 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00075 0.00379 0.00709 0.00008 0.00000 0.00000 0.00000 0.00000 0.00000RADAEVA_RESPONSE_TO_IFNA1_UP
0.03142 0.01065 0.00543 0.00171 0.00043 0.03933 0.02903 0.00196 0.00127LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP
0.00923 0.00006 0.00031 0.00036 0.00023 0.01170 0.00027 0.00052 0.01124ELVIDGE_HYPOXIA_UP
0.01474 0.00018 0.00021 0.00031 0.00068 0.03874 0.00042 0.00000 0.00000AMIT_EGF_RESPONSE_40_HELA
0.00289 0.02677 0.00618 0.00683 0.00007 0.00254 0.00166 0.00000 0.00001BOWIE_RESPONSE_TO_EXTRACELLULAR_MATRIX
0.00623 0.00052 0.00709 0.00028 0.09197 0.00034 0.00004 0.00856 0.00000NETPATH_IL_7_PATHWAY_UP
0.00000 0.00000 0.00006 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000BROWNE_INTERFERON_RESPONSIVE_GENES
0.00024 0.00000 0.00184 0.00000 0.00000 0.01384 0.00174 0.00000 0.00000THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.01109 0.00012 0.00708 0.00004 0.00008 0.00081 0.00001 0.00000 0.00220TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP
0.05386 0.03831 0.09575 0.00741 0.00096 0.01826 0.00022 0.00015 0.00141ROETH_TERT_TARGETS_UP
0.00998 0.02964 0.01867 0.00729 0.00030 0.04656 0.08132 0.00199 0.00807TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP
0.00000 0.00000 0.00000 0.00000 0.00001 0.00055 0.00001 0.00000 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00200 0.00001 0.01647 0.00004 0.00004 0.00000 0.00000 0.00000 0.00000MARKEY_RB1_ACUTE_LOF_UP
0.00045 0.00000 0.00058 0.00008 0.00736 0.00013 0.00000 0.00060 0.00000KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00299 0.00751 0.00129 0.00049 0.00065 0.00698 0.00053 0.00000 0.00144XU_AKT1_TARGETS_6HR
0.08327 0.08630 0.08169 0.06140 0.04416 0.00001 0.00002 0.00021 0.00002OSADA_ASCL1_TARGETS_DN
0.01528 0.00218 0.00294 0.00016 0.01472 0.02454 0.01577 0.01566 0.00000VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP
0.00615 0.00008 0.00356 0.00032 0.00000 0.00475 0.00144 0.00000 0.00000NUYTTEN_EZH2_TARGETS_UP
0.00646 0.00003 0.00201 0.00013 0.01422 0.00000 0.00000 0.00002 0.00000DUTTA_APOPTOSIS_VIA_NFKB
0.05456 0.00162 0.00857 0.00652 0.01413 0.00000 0.00000 0.01142 0.03522POOLA_INVASIVE_BREAST_CANCER_UP
0.00000 0.00000 0.00018 0.00000 0.00199 0.00000 0.00000 0.00000 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.06210 0.00439 0.02147 0.03733 0.00003 0.01711 0.00259 0.00477 0.10906RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN
0.02669 0.11363 0.12805 0.08100 0.01016 0.00000 0.00000 0.00067 0.00647LIU_VAV3_PROSTATE_CARCINOGENESIS_UP
0.00018 0.00000 0.00069 0.00000 0.00001 0.00001 0.00000 0.00000 0.00000SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP
0.00001 0.00073 0.00079 0.00003 0.00000 0.00000 0.00000 0.00000 0.00000BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS
0.06500 0.00259 0.15482 0.09530 0.05773 0.03630 0.01648 0.00205 0.00004NCI_NFAT_TFPATHWAY
0.00000 0.00000 0.00000 0.00000 0.00000 0.01092 0.00039 0.00002 0.00000ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.19163 0.00121 0.06839 0.05249 0.00000 0.00123 0.00006 0.00000 0.01985RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP
0.00150 0.01083 0.00026 0.00099 0.00011 0.02809 0.00507 0.10086 0.00000ONDER_CDH1_TARGETS_3_DN
0.00077 0.00000 0.00029 0.00004 0.02592 0.07404 0.00037 0.00000 0.00046AMIT_EGF_RESPONSE_120_HELA
0.03866 0.10223 0.02528 0.08621 0.00001 0.00000 0.00000 0.00000 0.04537NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP
0.07010 0.00401 0.02280 0.00048 0.16188 0.13021 0.06671 0.00036 0.00004HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS
0.10871 0.00012 0.10917 0.00659 0.01127 0.01021 0.00276 0.02002 0.00438NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP
0.09112 0.00178 0.07195 0.06188 0.01810 0.00549 0.00161 0.00299 0.00949FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP
0.06926 0.00004 0.01519 0.00442 0.00186 0.11984 0.01067 0.00019 0.02164WINTER_HYPOXIA_METAGENE
0.00049 0.00000 0.00050 0.00008 0.00000 0.00000 0.00000 0.00000 0.00000MCLACHLAN_DENTAL_CARIES_UP
0.09603 0.00903 0.02695 0.00443 0.01700 0.02606 0.00261 0.00756 0.00098GAJATE_RESPONSE_TO_TRABECTEDIN_UP
0.00882 0.01325 0.03258 0.03715 0.09674 0.00936 0.00209 0.00177 0.00184NEWMAN_ERCC6_TARGETS_UP
0.00017 0.00000 0.00000 0.00001 0.00004 0.00428 0.00028 0.00000 0.01026PODAR_RESPONSE_TO_ADAPHOSTIN_UP
0.00000 0.00000 0.00000 0.00000 0.00001 0.00000 0.00000 0.00000 0.00000FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.00381 0.00205 0.00563 0.00219 0.02021 0.00000 0.00000 0.00014 0.00843LEE_LIVER_CANCER_E2F1_UP
0.15470 0.01106 0.06979 0.02930 0.00125 0.00572 0.00085 0.00011 0.00020TAVOR_CEBPA_TARGETS_UP
0.00000 0.00000 0.00000 0.00000 0.00001 0.00000 0.00000 0.00000 0.00000GAURNIER_PSMD4_TARGETS
0.00210 0.00040 0.00251 0.00028 0.07324 0.00000 0.00000 0.00000 0.00002HELLER_SILENCED_BY_METHYLATION_UP
0.00158 0.00368 0.00375 0.00097 0.00061 0.00010 0.00070 0.00000 0.00002GRANDVAUX_IFN_RESPONSE_NOT_VIA_IRF3
0.00492 0.01810 0.00711 0.00039 0.00001 0.00000 0.00000 0.00000 0.00000FARMER_BREAST_CANCER_CLUSTER_1
0.00150 0.00632 0.00593 0.00077 0.00001 0.00015 0.00001 0.00000 0.00000BOWIE_RESPONSE_TO_TAMOXIFEN
0.04808 0.03490 0.00980 0.11465 0.03199 0.02810 0.04099 0.00117 0.00071SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER
0.00738 0.01073 0.00424 0.00135 0.03343 0.11644 0.10943 0.00047 0.00791GOZGIT_ESR1_TARGETS_DN
0.00491 0.00565 0.00471 0.02548 0.00005 0.00000 0.00000 0.01556 0.09710MARKEY_RB1_CHRONIC_LOF_DN
0.00000 0.00008 0.00015 0.00218 0.00011 0.00000 0.00000 0.00021 0.00769ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP
0.03531 0.04505 0.17478 0.00186 0.18259 0.00021 0.00002 0.09678 0.00044NCI_AMB2_NEUTROPHILS_PATHWAY
0.00087 0.00824 0.00018 0.00148 0.12803 0.00000 0.00000 0.07952 0.00006SMID_BREAST_CANCER_LUMINAL_B_DN
0.00000 0.00000 0.00000 0.00000 0.00000 0.00269 0.00012 0.00000 0.00000ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.00141 0.00000 0.00000 0.00004 0.02216 0.00047 0.00032 0.00002 0.00083GESERICK_TERT_TARGETS_DN
0.00066 0.00893 0.01777 0.00097 0.02237 0.00573 0.00758 0.00051 0.00025NOJIMA_SFRP2_TARGETS_DN
0.14589 0.03066 0.06583 0.05580 0.05923 0.05857 0.00363 0.03994 0.06355NETPATH_TGFBETA_RECEPTOR_PATHWAY_DOWN
0.00013 0.00000 0.00007 0.00000 0.00040 0.04018 0.00009 0.00013 0.00011AMIT_SERUM_RESPONSE_120_MCF10A
0.06014 0.02213 0.00222 0.00673 0.02059 0.15614 0.11885 0.00000 0.00014BROWNE_HCMV_INFECTION_2HR_UP
0.00469 0.07080 0.00848 0.01117 0.02477 0.00000 0.00000 0.00022 0.08000LEE_LIVER_CANCER_MYC_E2F1_UP
0.00757 0.00406 0.00078 0.00270 0.00002 0.17152 0.01412 0.00000 0.00001SESTO_RESPONSE_TO_UV_C3
0.00001 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.01123 0.00001 0.04624 0.00068 0.00001 0.00000 0.00000 0.00000 0.00002BROCKE_APOPTOSIS_REVERSED_BY_IL6
0.00179 0.00000 0.00109 0.00000 0.00027 0.00175 0.00022 0.00000 0.00000GEISS_RESPONSE_TO_DSRNA_UP
0.00514 0.00011 0.00272 0.00007 0.00032 0.00015 0.00030 0.00000 0.00000GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN
0.08860 0.01652 0.11365 0.13034 0.14599 0.07476 0.03452 0.08955 0.00831NCI_P53DOWNSTREAMPATHWAY
0.00093 0.02956 0.00070 0.00226 0.07166 0.00221 0.00050 0.00666 0.00653SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1
0.00709 0.00156 0.00272 0.00140 0.04187 0.00000 0.00000 0.00051 0.00000NCI_IL12_2PATHWAY
0.00018 0.00001 0.00000 0.00000 0.00125 0.09979 0.02576 0.00047 0.00000ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP
0.00000 0.00000 0.00016 0.00000 0.00054 0.00003 0.00000 0.00000 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.02045 0.00018 0.03630 0.00004 0.00000 0.00053 0.00083 0.00000 0.00000ZHU_CMV_ALL_UP
0.00027 0.00177 0.01680 0.00219 0.02242 0.00000 0.00000 0.00000 0.00000KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.09623 0.01782 0.00621 0.00041 0.00777 0.16268 0.15053 0.04117 0.00002OKUMURA_INFLAMMATORY_RESPONSE_LPS
0.00139 0.00193 0.00058 0.00168 0.02848 0.00021 0.00011 0.13990 0.00010LEE_LIVER_CANCER_HEPATOBLAST
0.00000 0.00000 0.00000 0.00000 0.00001 0.00040 0.00000 0.00000 0.00003NAGASHIMA_EGF_SIGNALING_UP
0.03824 0.01030 0.01506 0.02107 0.00007 0.00153 0.00184 0.06667 0.00002KEGG_TYPE_I_DIABETES_MELLITUS
0.00490 0.00025 0.00029 0.00000 0.07424 0.00143 0.00093 0.00030 0.00046HUANG_DASATINIB_RESISTANCE_UP
0.00000 0.00000 0.00000 0.00000 0.01523 0.02646 0.00070 0.00004 0.00000AMIT_EGF_RESPONSE_60_MCF10A
0.03435 0.00001 0.00034 0.00008 0.00031 0.00358 0.00151 0.00000 0.00000HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.00172 0.00224 0.00037 0.00304 0.02668 0.01772 0.00340 0.00000 0.00018NOJIMA_SFRP2_TARGETS_UP
0.10433 0.00007 0.00176 0.00028 0.00002 0.00013 0.00000 0.00002 0.00000CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN
0.00000 0.00001 0.00000 0.00000 0.02915 0.00000 0.00000 0.00225 0.00000KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.03187 0.01068 0.01499 0.02172 0.00069 0.01170 0.01388 0.00079 0.13852CHEN_HOXA5_TARGETS_6HR_UP
0.00468 0.00107 0.00038 0.00145 0.00001 0.00123 0.00006 0.00000 0.00000MISSIAGLIA_REGULATED_BY_METHYLATION_UP
0.05054 0.00133 0.02220 0.00508 0.00015 0.00021 0.00000 0.00000 0.01400SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP
0.00000 0.00000 0.00000 0.00000 0.00001 0.00488 0.00301 0.00000 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.17031 0.05654 0.16613 0.05832 0.01521 0.04644 0.03472 0.00017 0.19530CHEN_LVAD_SUPPORT_OF_FAILING_HEART_DN
0.00001 0.00114 0.00037 0.00013 0.00000 0.00000 0.00000 0.00000 0.00000ZHANG_INTERFERON_RESPONSE
0.09883 0.07816 0.03094 0.00008 0.00167 0.00135 0.00059 0.00000 0.00015CHANG_IMMORTALIZED_BY_HPV31_DN
0.04761 0.00829 0.00954 0.01017 0.05925 0.00000 0.00000 0.00025 0.00003CROONQUIST_STROMAL_STIMULATION_UP
0.08847 0.18770 0.02194 0.14131 0.00938 0.00006 0.00000 0.00029 0.07586LEE_LIVER_CANCER_MYC_TGFA_UP
0.00406 0.00860 0.01474 0.00023 0.04438 0.00037 0.00000 0.00814 0.00133SA_MMP_CYTOKINE_CONNECTION
0.00185 0.00154 0.00022 0.00037 0.01542 0.03101 0.00175 0.01212 0.00001HALMOS_CEBPA_TARGETS_UP
0.01387 0.09748 0.00037 0.00041 0.00267 0.01150 0.00166 0.02779 0.00033WU_CELL_MIGRATION
0.00001 0.00000 0.00029 0.00000 0.00031 0.00000 0.00000 0.00000 0.00004WALLACE_PROSTATE_CANCER_RACE_UP
0.00023 0.00001 0.00069 0.00000 0.00001 0.00001 0.00000 0.00000 0.00000TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP
0.01705 0.00014 0.03216 0.00041 0.00001 0.00000 0.00017 0.00000 0.00004KIM_LRRC3B_TARGETS
0.00735 0.00023 0.01137 0.00038 0.01805 0.00147 0.00059 0.00000 0.00002HORIUCHI_WTAP_TARGETS_UP
0.00145 0.00024 0.00146 0.00040 0.00001 0.00001 0.00000 0.00000 0.00000NETPATH_IL_4_PATHWAY_DOWN
0.01516 0.01934 0.03385 0.02619 0.00298 0.15904 0.02715 0.01382 0.01179GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN
0.00031 0.00006 0.00072 0.00009 0.01146 0.18500 0.08720 0.00000 0.00317MAHADEVAN_RESPONSE_TO_MP470_DN
0.00114 0.00537 0.00167 0.00028 0.00008 0.00000 0.00001 0.00000 0.00000UROSEVIC_RESPONSE_TO_IMIQUIMOD
0.00957 0.19320 0.00782 0.03244 0.15353 0.04066 0.01998 0.02415 0.00632RIGGI_EWING_SARCOMA_PROGENITOR_UP
0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP
0.00250 0.00004 0.00029 0.00029 0.00000 0.00160 0.00025 0.00067 0.00034HARRIS_HYPOXIA
0.00062 0.00004 0.00015 0.00570 0.05671 0.02531 0.00015 0.00019 0.00023NETPATH_KIT_RECEPTOR_PATHWAY_UP
0.00700 0.00000 0.02263 0.00008 0.00000 0.00000 0.00000 0.00000 0.00002FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN
0.04202 0.00563 0.04762 0.00056 0.00000 0.00030 0.00214 0.00000 0.00000DER_IFN_BETA_RESPONSE_UP
0.03172 0.16954 0.06839 0.02491 0.01474 0.01306 0.00356 0.00004 0.01475TSAI_DNAJB4_TARGETS_UP
0.05961 0.00012 0.02538 0.00299 0.00000 0.00144 0.00056 0.00000 0.00002DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP
0.00195 0.00004 0.00040 0.00020 0.00061 0.00053 0.00000 0.00000 0.10451TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN
0.04922 0.00286 0.00165 0.00121 0.00399 0.09168 0.01034 0.00571 0.02558KAN_RESPONSE_TO_ARSENIC_TRIOXIDE
0.00000 0.00000 0.00018 0.00003 0.00020 0.00000 0.00000 0.00000 0.00000BASSO_CD40_SIGNALING_UP
0.01664 0.00034 0.00683 0.00078 0.01298 0.09628 0.00264 0.00011 0.00702TIAN_TNF_SIGNALING_NOT_VIA_NFKB
0.00002 0.00000 0.00000 0.00000 0.00045 0.00648 0.00000 0.00000 0.00000NAGASHIMA_NRG1_SIGNALING_UP
0.00016 0.00006 0.00021 0.00008 0.00507 0.00161 0.00004 0.00127 0.00002MARZEC_IL2_SIGNALING_UP
0.00000 0.00001 0.00018 0.00008 0.09270 0.00003 0.00027 0.02521 0.00037SOUCEK_MYC_TARGETS
0.00017 0.00000 0.00000 0.00004 0.00142 0.17707 0.01086 0.00228 0.05842TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN
0.00251 0.00901 0.01871 0.02450 0.12871 0.00000 0.00000 0.02453 0.05549BOYLAN_MULTIPLE_MYELOMA_C_D_DN
0.13677 0.16203 0.05840 0.12784 0.05033 0.07345 0.11589 0.04554 0.02814ZERBINI_RESPONSE_TO_SULINDAC_UP
0.02307 0.00001 0.00270 0.00101 0.01132 0.00034 0.00005 0.01866 0.14289BILBAN_B_CLL_LPL_DN
0.11437 0.01616 0.03028 0.06088 0.17037 0.00434 0.00010 0.00019 0.00496WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP
0.03004 0.01752 0.00030 0.00013 0.01616 0.12793 0.08461 0.01999 0.00002CROMER_TUMORIGENESIS_UP
0.00025 0.00006 0.00018 0.00000 0.00004 0.00029 0.00001 0.00004 0.00000MAHADEVAN_RESPONSE_TO_MP470_UP
0.00434 0.00337 0.02608 0.00021 0.00177 0.00000 0.00000 0.00000 0.00002ZHAN_MULTIPLE_MYELOMA_LB_DN
0.01336 0.17971 0.01127 0.11422 0.00296 0.01760 0.00607 0.00343 0.00009KEGG_AUTOIMMUNE_THYROID_DISEASE
0.00508 0.00007 0.01472 0.00050 0.06128 0.00947 0.00156 0.00018 0.00016FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.00208 0.00000 0.00000 0.00000 0.00000 0.00696 0.00024 0.00000 0.00000BILD_HRAS_ONCOGENIC_SIGNATURE
0.00068 0.00025 0.01462 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000SANA_RESPONSE_TO_IFNG_UP
0.00000 0.00007 0.00000 0.00000 0.00001 0.00001 0.00000 0.00000 0.00000LIANG_SILENCED_BY_METHYLATION_2
0.05660 0.06147 0.06189 0.02597 0.00016 0.01097 0.00307 0.00000 0.00003DAUER_STAT3_TARGETS_UP
0.00000 0.00000 0.00000 0.00000 0.00553 0.00000 0.00000 0.00171 0.00000NETPATH_IL_3_PATHWAY_UP
0.00018 0.00001 0.00000 0.00005 0.05104 0.06898 0.00466 0.00534 0.00000ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN
0.00675 0.00695 0.07814 0.01693 0.00055 0.00000 0.00000 0.00007 0.00028KEGG_LEISHMANIA_INFECTION
0.06470 0.01898 0.14030 0.00389 0.00000 0.00000 0.00122 0.00000 0.00000DER_IFN_ALPHA_RESPONSE_UP
0.02663 0.00000 0.00019 0.00028 0.02795 0.05909 0.00102 0.00000 0.00523AMIT_EGF_RESPONSE_60_HELA
0.16114 0.00197 0.08832 0.06783 0.03814 0.02809 0.03269 0.00008 0.08973ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN
0.19546 0.00000 0.00332 0.00060 0.03353 0.00705 0.00358 0.08977 0.00016BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN
0.01506 0.00001 0.00807 0.00074 0.00000 0.01709 0.00291 0.00006 0.00050CHEN_HOXA5_TARGETS_9HR_UP
0.11521 0.00772 0.01250 0.01385 0.04745 0.03944 0.00111 0.01541 0.00004DAZARD_UV_RESPONSE_CLUSTER_G2
0.09928 0.01324 0.06958 0.00009 0.00000 0.00023 0.00004 0.00000 0.00000EINAV_INTERFERON_SIGNATURE_IN_CANCER
0.02712 0.00001 0.00711 0.00159 0.00007 0.00007 0.00000 0.00000 0.00001NETPATH_IL_5_PATHWAY_UP
0.00078 0.00001 0.00065 0.00014 0.00000 0.00000 0.00000 0.00001 0.00002MCLACHLAN_DENTAL_CARIES_DN
0.00363 0.00070 0.00288 0.01133 0.00001 0.00009 0.00014 0.00549 0.00000KEGG_ALLOGRAFT_REJECTION
0.00000 0.00000 0.00000 0.00004 0.00799 0.00705 0.00005 0.00000 0.00142AMIT_SERUM_RESPONSE_40_MCF10A
0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.13166 0.01551 0.00993 0.01760 0.06392 0.11721 0.06950 0.00601 0.15460HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP
0.00810 0.00008 0.00398 0.00030 0.00097 0.00007 0.00003 0.00000 0.00000GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00369 0.00014 0.00489 0.00226 0.00060 0.06066 0.01806 0.00028 0.08735CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP
0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00025 0.00004 0.00061 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000ZHU_CMV_8_HR_UP
0.00000 0.00006 0.00000 0.00004 0.00012 0.03146 0.00595 0.05068 0.00000BIOCARTA_INFLAM_PATHWAY
0.00017 0.00000 0.00022 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000SANA_TNF_SIGNALING_UP
0.00116 0.00001 0.00043 0.00000 0.00004 0.00104 0.00084 0.00000 0.00000TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP
0.02027 0.00720 0.02901 0.00318 0.04900 0.00000 0.00004 0.04359 0.00000NCI_IL27PATHWAY
0.00044 0.00001 0.00236 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000MOSERLE_IFNA_RESPONSE
0.18303 0.00001 0.00804 0.00023 0.00306 0.00000 0.00000 0.00036 0.01672SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP
0.02769 0.00001 0.01129 0.00026 0.00023 0.15854 0.01080 0.01303 0.00002SENESE_HDAC1_AND_HDAC2_TARGETS_UP
0.00000 0.00000 0.00004 0.00000 0.00000 0.00000 0.00000 0.00000 0.00011FOSTER_INFLAMMATORY_RESPONSE_LPS_UP
0.04816 0.02830 0.12689 0.13527 0.00550 0.00639 0.00252 0.10630 0.00194BIOCARTA_ASBCELL_PATHWAY
0.01150 0.00321 0.02501 0.02068 0.00954 0.03408 0.00223 0.00001 0.00014XU_HGF_TARGETS_INDUCED_BY_AKT1_6HR
0.00065 0.00111 0.00022 0.00011 0.00554 0.00757 0.00036 0.00500 0.00002ONDER_CDH1_TARGETS_2_DN
0.08354 0.00001 0.01901 0.00109 0.00009 0.09820 0.03717 0.04425 0.00079SENESE_HDAC1_TARGETS_UP
0.00080 0.00000 0.00030 0.00006 0.00000 0.00262 0.00004 0.00000 0.00000HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00000 0.00344 0.00043 0.00057 0.01434 0.00000 0.00000 0.11260 0.00021KEGG_HEMATOPOIETIC_CELL_LINEAGE
0.00075 0.05211 0.00019 0.00360 0.12933 0.00029 0.00974 0.04041 0.03679SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2
0.01612 0.00000 0.00039 0.00000 0.01564 0.13365 0.00017 0.00007 0.00002KIM_WT1_TARGETS_UP
0.07491 0.00001 0.00979 0.00039 0.00256 0.09963 0.02396 0.00552 0.00076SENESE_HDAC3_TARGETS_UP
0.00145 0.01094 0.00200 0.00805 0.00588 0.01044 0.00252 0.00059 0.00000KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY
0.00000 0.00000 0.00000 0.00000 0.00007 0.02814 0.00336 0.00000 0.00044UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.06052 0.00072 0.06359 0.00209 0.00000 0.00000 0.00000 0.00000 0.00023JISON_SICKLE_CELL_DISEASE_UP
0.00000 0.00000 0.00006 0.00004 0.00001 0.00000 0.00000 0.00000 0.08966HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN
0.01073 0.00001 0.00177 0.00020 0.00595 0.14492 0.03956 0.00006 0.00015DASU_IL6_SIGNALING_UP
0.01114 0.00045 0.00028 0.00017 0.00142 0.04510 0.00131 0.00043 0.01098ELVIDGE_HYPOXIA_BY_DMOG_UP
0.00024 0.00000 0.00037 0.00000 0.00001 0.00001 0.00009 0.00002 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00000 0.00000 0.00000 0.00000 0.00001 0.00511 0.00265 0.00000 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.08451 0.00010 0.04370 0.05022 0.00518 0.10538 0.00899 0.00039 0.00000ZUCCHI_METASTASIS_DN
0.00017 0.00006 0.00176 0.00004 0.01517 0.00276 0.00009 0.02153 0.00649LU_IL4_SIGNALING
0.12398 0.00232 0.04754 0.05386 0.00007 0.01712 0.00473 0.00000 0.00005RUTELLA_RESPONSE_TO_HGF_UP
0.02502 0.00024 0.02844 0.00119 0.01526 0.07569 0.00099 0.00000 0.00005PRAMOONJAGO_SOX4_TARGETS_UP
0.00000 0.00000 0.00000 0.00000 0.00887 0.05114 0.00107 0.00000 0.02690PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.00476 0.09440 0.07743 0.19674 0.05106 0.19587 0.02901 0.15152 0.00080LU_TUMOR_ENDOTHELIAL_MARKERS_UP