BICLUSTER_ID : UPREG-200
PATHOGENS /4/ : pseudomonas aeruginosa,bifidobacterium bifidum,yersinia enterocolitica,helicobacter pylori
TARGETS /6/ : IL6, CCL20, PTGS2, GCH1, CCL2, NP
Gene SetLeading Edge Genes
NETPATH IL 4 PATHWAY DOWNIL6, CCL20, GADD45B, PTGS2, CCL2, IRF1, CXCL2
NETPATH IL 1 PATHWAY UPCCL20, LIF, CXCL1, NP, FOSL1, IL6, PTGS2, CXCL2
NCI IL23PATHWAYIL6, CXCL1, CCL2
NETPATH IL 9 PATHWAY UPCCL2, JUNB
GERY CEBP TARGETSATF3, GADD45B, IFRD1, CXCL1, GCH1, JUNB, DUSP1
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
MISSIAGLIA REGULATED BY METHYLATION UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
LEONARD HYPOXIA
BIOCARTA STEM PATHWAY
MAHAJAN RESPONSE TO IL1A UP
BIOCARTA EPONFKB PATHWAY
ZHANG INTERFERON RESPONSE
REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS
ICHIBA GRAFT VERSUS HOST DISEASE D7 UP
REACTOME PEPTIDE LIGAND BINDING RECEPTORS
LINDSTEDT DENDRITIC CELL MATURATION B
KRASNOSELSKAYA ILF3 TARGETS UP
RASHI RESPONSE TO IONIZING RADIATION 2
LINDSTEDT DENDRITIC CELL MATURATION A
WALLACE PROSTATE CANCER RACE UP
ELVIDGE HYPOXIA UP
KIM LRRC3B TARGETS
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
AMIT EGF RESPONSE 40 HELA
BOWIE RESPONSE TO EXTRACELLULAR MATRIX
MAHADEVAN RESPONSE TO MP470 DN
UROSEVIC RESPONSE TO IMIQUIMOD
BROWNE INTERFERON RESPONSIVE GENES
HARRIS HYPOXIA
NETPATH KIT RECEPTOR PATHWAY UP
ROETH TERT TARGETS UP
DER IFN BETA RESPONSE UP
BIOCARTA LAIR PATHWAY
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP
HINATA NFKB TARGETS KERATINOCYTE UP
BIOCARTA CYTOKINE PATHWAY
MARKEY RB1 ACUTE LOF UP
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
BASSO CD40 SIGNALING UP
SOUCEK MYC TARGETS
DUTTA APOPTOSIS VIA NFKB
ZERBINI RESPONSE TO SULINDAC UP
DIRMEIER LMP1 RESPONSE EARLY
DER IFN GAMMA RESPONSE UP
MAHADEVAN RESPONSE TO MP470 UP
ZHAN MULTIPLE MYELOMA LB DN
LIU VAV3 PROSTATE CARCINOGENESIS UP
FERRARI RESPONSE TO FENRETINIDE UP
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
SEITZ NEOPLASTIC TRANSFORMATION BY 8P DELETION UP
BENNETT SYSTEMIC LUPUS ERYTHEMATOSUS
KEGG RIG I LIKE RECEPTOR SIGNALING PATHWAY
BILD HRAS ONCOGENIC SIGNATURE
SANA RESPONSE TO IFNG UP
ONDER CDH1 TARGETS 3 DN
NETPATH IL 3 PATHWAY UP
DAUER STAT3 TARGETS UP
LIANG SILENCED BY METHYLATION 2
NAKAYAMA SOFT TISSUE TUMORS PCA1 UP
BIOCARTA RANKL PATHWAY
NETPATH IL 6 PATHWAY UPGADD45B, CXCL1, JUNB, IRF1, MAP3K8
NIELSEN MALIGNAT FIBROUS HISTIOCYTOMA UP
DER IFN ALPHA RESPONSE UP
MCLACHLAN DENTAL CARIES UP
MENSE HYPOXIA UP
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX CHUK KPNA3 NFKB2 NFKBIB REL IKBKG NFKB1 NFKBIE RELB NFKBIA RELA TNIP2
ISHIKAWA STING SIGNALING
EINAV INTERFERON SIGNATURE IN CANCER
DAZARD UV RESPONSE CLUSTER G2
CHEN HOXA5 TARGETS 9HR UP
MCLACHLAN DENTAL CARIES DN
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
GRANDVAUX IFN RESPONSE NOT VIA IRF3
GRAHAM CML QUIESCENT VS CML DIVIDING UP
BOWIE RESPONSE TO TAMOXIFEN
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
ZHU CMV 8 HR UP
BIERIE INFLAMMATORY RESPONSE TGFB1
ZHOU INFLAMMATORY RESPONSE LPS UP
BIOCARTA INFLAM PATHWAY
SANA TNF SIGNALING UP
MOSERLE IFNA RESPONSE
WONG ENDMETRIUM CANCER UP
FOSTER INFLAMMATORY RESPONSE LPS UP
LEE LIVER CANCER MYC E2F1 UP
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
VERHAAK AML WITH NPM1 MUTATED UP
GEISS RESPONSE TO DSRNA UP
KEGG CYTOSOLIC DNA SENSING PATHWAY
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
BIOCARTA GRANULOCYTES PATHWAY
ELVIDGE HYPOXIA BY DMOG UP
AMIT EGF RESPONSE 120 MCF10A
TIAN TNF SIGNALING VIA NFKB
ZHU CMV ALL UP
KEGG TOLL LIKE RECEPTOR SIGNALING PATHWAY
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
LEE LIVER CANCER HEPATOBLAST
ZUCCHI METASTASIS DN
BERTUCCI MEDULLARY VS DUCTAL BREAST CANCER UP
NAGASHIMA EGF SIGNALING UP
PRAMOONJAGO SOX4 TARGETS UP
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
HINATA NFKB TARGETS FIBROBLAST UP
AMIT EGF RESPONSE 60 MCF10A
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
yersinia enterocolitica p60 bl6pseudomonas aeruginosa fdr440bifidobacterium bifidumhelicobacter pylori kx1 npgecGeneSet Name
0.00146 0.00000 0.00103 0.00644NETPATH_IL_4_PATHWAY_DOWN
0.00000 0.00000 0.00007 0.00201NETPATH_IL_1_PATHWAY_UP
0.00000 0.01471 0.00000 0.14576NCI_IL23PATHWAY
0.00016 0.04269 0.00572 0.00667NETPATH_IL_9_PATHWAY_UP
0.00040 0.00131 0.00008 0.04422GERY_CEBP_TARGETS
0.00000 0.00195 0.00000 0.06985KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.00038 0.00000 0.00000 0.00255MISSIAGLIA_REGULATED_BY_METHYLATION_UP
0.00000 0.00010 0.01391 0.09695OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.00021 0.01700 0.00214 0.18497GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.01346 0.00131 0.00822 0.00008LEONARD_HYPOXIA
0.03650 0.01042 0.06747 0.01484BIOCARTA_STEM_PATHWAY
0.00010 0.00044 0.00474 0.00083MAHAJAN_RESPONSE_TO_IL1A_UP
0.15613 0.00002 0.06360 0.04104BIOCARTA_EPONFKB_PATHWAY
0.00037 0.00495 0.00000 0.00002ZHANG_INTERFERON_RESPONSE
0.00794 0.17577 0.05369 0.01155REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS
0.00011 0.00068 0.00000 0.00000ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP
0.00054 0.02145 0.01762 0.00213REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
0.04591 0.00000 0.00000 0.00011LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00309 0.11846 0.13661 0.02655KRASNOSELSKAYA_ILF3_TARGETS_UP
0.00297 0.00000 0.00098 0.10813RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.00029 0.00003 0.00005 0.00003LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00029 0.15257 0.00167 0.03695WALLACE_PROSTATE_CANCER_RACE_UP
0.00031 0.16459 0.02232 0.11617ELVIDGE_HYPOXIA_UP
0.03216 0.02984 0.00007 0.00152KIM_LRRC3B_TARGETS
0.00563 0.00064 0.01539 0.00098IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.00021 0.15015 0.00190 0.12195AMIT_EGF_RESPONSE_40_HELA
0.00618 0.03539 0.00216 0.00059BOWIE_RESPONSE_TO_EXTRACELLULAR_MATRIX
0.00072 0.02760 0.00016 0.09518MAHADEVAN_RESPONSE_TO_MP470_DN
0.00167 0.00512 0.00005 0.00000UROSEVIC_RESPONSE_TO_IMIQUIMOD
0.00006 0.00002 0.00000 0.00000BROWNE_INTERFERON_RESPONSIVE_GENES
0.00029 0.00003 0.05400 0.08612HARRIS_HYPOXIA
0.00015 0.18259 0.08735 0.09166NETPATH_KIT_RECEPTOR_PATHWAY_UP
0.09575 0.10447 0.00294 0.00396ROETH_TERT_TARGETS_UP
0.04762 0.00222 0.02261 0.00085DER_IFN_BETA_RESPONSE_UP
0.00330 0.01830 0.01086 0.11387BIOCARTA_LAIR_PATHWAY
0.02538 0.00448 0.04303 0.02451DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP
0.00000 0.00000 0.00013 0.00256HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00009 0.00347 0.00000 0.15912BIOCARTA_CYTOKINE_PATHWAY
0.01647 0.01820 0.00000 0.00008MARKEY_RB1_ACUTE_LOF_UP
0.00058 0.00034 0.00000 0.06948KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00018 0.00000 0.00006 0.12757BASSO_CD40_SIGNALING_UP
0.00018 0.02994 0.00012 0.00009SOUCEK_MYC_TARGETS
0.00201 0.00513 0.00215 0.05736DUTTA_APOPTOSIS_VIA_NFKB
0.05840 0.03840 0.11328 0.06538ZERBINI_RESPONSE_TO_SULINDAC_UP
0.00018 0.00002 0.00294 0.06932DIRMEIER_LMP1_RESPONSE_EARLY
0.14426 0.00011 0.00551 0.00454DER_IFN_GAMMA_RESPONSE_UP
0.00018 0.00002 0.00318 0.00000MAHADEVAN_RESPONSE_TO_MP470_UP
0.02608 0.08690 0.01616 0.00155ZHAN_MULTIPLE_MYELOMA_LB_DN
0.12805 0.00848 0.10808 0.13833LIU_VAV3_PROSTATE_CARCINOGENESIS_UP
0.01472 0.00002 0.05329 0.11271FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.00012 0.00009 0.00006 0.00000REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
0.00069 0.05479 0.00442 0.00051SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP
0.00079 0.06522 0.00000 0.00000BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS
0.06399 0.03234 0.00015 0.14476KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00000 0.00028 0.00118 0.16783BILD_HRAS_ONCOGENIC_SIGNATURE
0.01462 0.04172 0.00000 0.00000SANA_RESPONSE_TO_IFNG_UP
0.00026 0.00194 0.01033 0.06938ONDER_CDH1_TARGETS_3_DN
0.00000 0.15088 0.01084 0.05322NETPATH_IL_3_PATHWAY_UP
0.06189 0.00085 0.00011 0.01934DAUER_STAT3_TARGETS_UP
0.00000 0.00005 0.00000 0.00000LIANG_SILENCED_BY_METHYLATION_2
0.02528 0.05763 0.13644 0.10968NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP
0.07528 0.01277 0.00140 0.04517BIOCARTA_RANKL_PATHWAY
0.00000 0.03716 0.00007 0.02074NETPATH_IL_6_PATHWAY_UP
0.10917 0.01078 0.04736 0.14559NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP
0.14030 0.00312 0.00081 0.00025DER_IFN_ALPHA_RESPONSE_UP
0.00050 0.00001 0.00155 0.02102MCLACHLAN_DENTAL_CARIES_UP
0.17416 0.05632 0.13132 0.00732MENSE_HYPOXIA_UP
0.07034 0.00016 0.00667 0.10289CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_CHUK_KPNA3_NFKB2_NFKBIB_REL_IKBKG__NFKB1_NFKBIE_RELB__NFKBIA_RELA_TNIP2
0.02216 0.06552 0.11417 0.00285ISHIKAWA_STING_SIGNALING
0.06958 0.03104 0.00000 0.00000EINAV_INTERFERON_SIGNATURE_IN_CANCER
0.01250 0.00228 0.03296 0.15355DAZARD_UV_RESPONSE_CLUSTER_G2
0.00807 0.00550 0.07447 0.00899CHEN_HOXA5_TARGETS_9HR_UP
0.00065 0.00017 0.00444 0.06509MCLACHLAN_DENTAL_CARIES_DN
0.00000 0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00002 0.00007 0.00000GAURNIER_PSMD4_TARGETS
0.00375 0.04085 0.00064 0.00007GRANDVAUX_IFN_RESPONSE_NOT_VIA_IRF3
0.00398 0.00002 0.00000 0.00796GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00593 0.04904 0.00013 0.00007BOWIE_RESPONSE_TO_TAMOXIFEN
0.00000 0.00000 0.00000 0.00002ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00061 0.06119 0.00006 0.00000ZHU_CMV_8_HR_UP
0.05248 0.00969 0.15084 0.00805BIERIE_INFLAMMATORY_RESPONSE_TGFB1
0.00000 0.00027 0.00000 0.00001ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00030 0.00002 0.04107BIOCARTA_INFLAM_PATHWAY
0.00022 0.00000 0.00000 0.00000SANA_TNF_SIGNALING_UP
0.00236 0.00512 0.00000 0.00000MOSERLE_IFNA_RESPONSE
0.05178 0.04320 0.02139 0.09571WONG_ENDMETRIUM_CANCER_UP
0.00004 0.09494 0.00000 0.03879FOSTER_INFLAMMATORY_RESPONSE_LPS_UP
0.00848 0.11981 0.02392 0.16806LEE_LIVER_CANCER_MYC_E2F1_UP
0.00030 0.00011 0.02116 0.06147HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00000 0.00218 0.02011 0.06454VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.00109 0.00007 0.00426 0.00002GEISS_RESPONSE_TO_DSRNA_UP
0.00200 0.01678 0.00006 0.00515KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY
0.00000 0.02749 0.08234 0.00603UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.01449 0.02115 0.01849 0.00519BIOCARTA_GRANULOCYTES_PATHWAY
0.00028 0.15685 0.00784 0.06336ELVIDGE_HYPOXIA_BY_DMOG_UP
0.00086 0.00020 0.01036 0.19126AMIT_EGF_RESPONSE_120_MCF10A
0.00016 0.00000 0.00000 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.03630 0.02420 0.03180 0.00201ZHU_CMV_ALL_UP
0.01680 0.09337 0.00000 0.14588KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00037 0.00000 0.00000 0.00039GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00000 0.00011 0.01525 0.10013OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.00058 0.00243 0.02142 0.18870LEE_LIVER_CANCER_HEPATOBLAST
0.04370 0.00002 0.03751 0.02425ZUCCHI_METASTASIS_DN
0.18489 0.00131 0.11780 0.09552BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP
0.00000 0.00002 0.09324 0.01564NAGASHIMA_EGF_SIGNALING_UP
0.02844 0.00044 0.00000 0.00004PRAMOONJAGO_SOX4_TARGETS_UP
0.00000 0.06556 0.00605 0.15432PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.00034 0.00000 0.05376 0.05134HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.00000 0.00027 0.00467 0.04711AMIT_EGF_RESPONSE_60_MCF10A