BICLUSTER_ID : UPREG-218
PATHOGENS /4/ : yersinia enterocolitica,aeromonas caviae,helicobacter pylori,ehrlichia chaffeensis
TARGETS /4/ : VCAM1, SLC1A5, LCN2, JUN
Gene SetLeading Edge Genes
NETPATH IL 9 PATHWAY UPLCN2
NETPATH IL 6 PATHWAY UPCXCL1, JUN, IRF1
NETPATH IL 5 PATHWAY UPSLC1A5, UPP1, CASP4, EGR2
NETPATH IL 4 PATHWAY UPVCAM1, UPP1, RBMS1, EGR2
NETPATH IL 2 PATHWAY UPSLC1A5, KLF6, UPP1
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
VARELA ZMPSTE24 TARGETS UP
AUJLA IL22 AND IL17A SIGNALING
ICHIBA GRAFT VERSUS HOST DISEASE D7 UP
LINDSTEDT DENDRITIC CELL MATURATION B
SA MMP CYTOKINE CONNECTION
LINDSTEDT DENDRITIC CELL MATURATION A
RADAEVA RESPONSE TO IFNA1 UP
WALLACE PROSTATE CANCER RACE UP
HORIUCHI WTAP TARGETS UP
NETPATH IL 4 PATHWAY DOWNGEM
NETPATH IL 7 PATHWAY UPCXCL1
RUTELLA RESPONSE TO CSF2RB AND IL4 DN
CHIARADONNA NEOPLASTIC TRANSFORMATION KRAS CDC25 DN
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION ERYTHROCYTE UP
ROETH TERT TARGETS UP
DER IFN BETA RESPONSE UP
HINATA NFKB TARGETS KERATINOCYTE UP
MARKEY RB1 ACUTE LOF UP
BASSO CD40 SIGNALING UP
SOUCEK MYC TARGETS
NUYTTEN EZH2 TARGETS UP
DUTTA APOPTOSIS VIA NFKB
DIRMEIER LMP1 RESPONSE EARLY
MAHADEVAN RESPONSE TO MP470 UP
KEGG INTESTINAL IMMUNE NETWORK FOR IGA PRODUCTION
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
RUTELLA RESPONSE TO HGF VS CSF2RB AND IL4 UP
DAUER STAT3 TARGETS UP
LIANG SILENCED BY METHYLATION 2
NETPATH IL 3 PATHWAY UP
NAKAYAMA SOFT TISSUE TUMORS PCA1 UP
KEGG LEISHMANIA INFECTION
LIAN LIPA TARGETS 6M
MCLACHLAN DENTAL CARIES UP
FOSTER INFLAMMATORY RESPONSE LPS DN
MCLACHLAN DENTAL CARIES DN
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
HELLER SILENCED BY METHYLATION UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
ZHU CMV 8 HR UP
NCI IL23PATHWAYCXCL1
SMID BREAST CANCER LUMINAL B DN
ZHOU INFLAMMATORY RESPONSE LPS UP
SANA TNF SIGNALING UP
FOSTER INFLAMMATORY RESPONSE LPS UP
XU HGF TARGETS INDUCED BY AKT1 6HR
VERHAAK AML WITH NPM1 MUTATED UP
LIAN LIPA TARGETS 3M
KEGG CHEMOKINE SIGNALING PATHWAY
GEISS RESPONSE TO DSRNA UP
KEGG CYTOSOLIC DNA SENSING PATHWAY
BIOCARTA GRANULOCYTES PATHWAY
NCI IL12 2PATHWAY
HESS TARGETS OF HOXA9 AND MEIS1 DN
ZHU CMV ALL UP
KEGG TOLL LIKE RECEPTOR SIGNALING PATHWAY
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
BERTUCCI MEDULLARY VS DUCTAL BREAST CANCER UP
SMID BREAST CANCER RELAPSE IN PLEURA DN
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
ehrlichia chaffeensis arkansayersinia enterocolitica p60 bl6ehrlichia chaffeensis wakullahelicobacter pylori kx2 mgepaeromonas caviaehrlichia chaffeensis libertyGeneSet Name
0.00097 0.00016 0.00000 0.00202 0.07320 0.00207NETPATH_IL_9_PATHWAY_UP
0.00003 0.00000 0.00000 0.01969 0.10211 0.00150NETPATH_IL_6_PATHWAY_UP
0.00007 0.00711 0.00000 0.00002 0.07327 0.05924NETPATH_IL_5_PATHWAY_UP
0.00011 0.00010 0.00000 0.00426 0.03395 0.02314NETPATH_IL_4_PATHWAY_UP
0.00029 0.00994 0.00006 0.04909 0.07215 0.01786NETPATH_IL_2_PATHWAY_UP
0.00000 0.00000 0.00000 0.00022 0.01697 0.00077KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.00021 0.00021 0.00547 0.00541 0.01924 0.01105GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.05834 0.15490 0.00013 0.00016 0.03175 0.00228VARELA_ZMPSTE24_TARGETS_UP
0.00697 0.00953 0.01045 0.01624 0.01459 0.12142AUJLA_IL22_AND_IL17A_SIGNALING
0.00000 0.00011 0.00000 0.07361 0.00000 0.00000ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP
0.00007 0.04591 0.00000 0.00000 0.00053 0.02223LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00037 0.01474 0.00000 0.11687 0.02492 0.00029SA_MMP_CYTOKINE_CONNECTION
0.00000 0.00029 0.00000 0.00000 0.00124 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00000 0.00709 0.00000 0.10408 0.00000 0.00009RADAEVA_RESPONSE_TO_IFNA1_UP
0.00000 0.00029 0.00000 0.14952 0.00000 0.00000WALLACE_PROSTATE_CANCER_RACE_UP
0.00147 0.01137 0.00059 0.01380 0.12653 0.01757HORIUCHI_WTAP_TARGETS_UP
0.00001 0.00146 0.00000 0.00009 0.01190 0.00340NETPATH_IL_4_PATHWAY_DOWN
0.00034 0.00709 0.00004 0.00019 0.16616 0.00005NETPATH_IL_7_PATHWAY_UP
0.00000 0.13271 0.00000 0.16288 0.02718 0.00000RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN
0.00000 0.00504 0.00022 0.10649 0.00603 0.00580CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN
0.00081 0.00708 0.00001 0.09686 0.16527 0.06656TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP
0.01826 0.09575 0.00022 0.08283 0.00363 0.00140ROETH_TERT_TARGETS_UP
0.00030 0.04762 0.00214 0.12957 0.00003 0.08872DER_IFN_BETA_RESPONSE_UP
0.00055 0.00000 0.00001 0.00000 0.06206 0.00058HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00000 0.01647 0.00000 0.09595 0.00000 0.00000MARKEY_RB1_ACUTE_LOF_UP
0.00000 0.00018 0.00000 0.01278 0.00110 0.00000BASSO_CD40_SIGNALING_UP
0.00003 0.00018 0.00027 0.00002 0.00169 0.00038SOUCEK_MYC_TARGETS
0.00475 0.00356 0.00144 0.02487 0.07444 0.11368NUYTTEN_EZH2_TARGETS_UP
0.00000 0.00201 0.00000 0.00000 0.05340 0.00023DUTTA_APOPTOSIS_VIA_NFKB
0.00000 0.00018 0.00000 0.00124 0.00564 0.00342DIRMEIER_LMP1_RESPONSE_EARLY
0.00029 0.00018 0.00001 0.00001 0.00240 0.00131MAHADEVAN_RESPONSE_TO_MP470_UP
0.00899 0.13918 0.00181 0.13453 0.07861 0.08853KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION
0.00000 0.00012 0.00000 0.00000 0.00008 0.00023REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
0.00123 0.06839 0.00006 0.13593 0.11676 0.00908RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP
0.01097 0.06189 0.00307 0.00008 0.05120 0.06350DAUER_STAT3_TARGETS_UP
0.00001 0.00000 0.00000 0.00002 0.00001 0.00000LIANG_SILENCED_BY_METHYLATION_2
0.00000 0.00000 0.00000 0.13629 0.00216 0.00030NETPATH_IL_3_PATHWAY_UP
0.00000 0.02528 0.00000 0.00467 0.00001 0.00000NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP
0.00000 0.07814 0.00000 0.01576 0.05933 0.00000KEGG_LEISHMANIA_INFECTION
0.00000 0.00177 0.00000 0.11920 0.01871 0.00000LIAN_LIPA_TARGETS_6M
0.00000 0.00050 0.00000 0.00006 0.00003 0.00000MCLACHLAN_DENTAL_CARIES_UP
0.00000 0.00000 0.00000 0.00146 0.00001 0.00078FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.00000 0.00065 0.00000 0.00040 0.00003 0.00000MCLACHLAN_DENTAL_CARIES_DN
0.00000 0.00000 0.00000 0.00000 0.00002 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00000 0.00000 0.00000 0.00001 0.00000GAURNIER_PSMD4_TARGETS
0.00000 0.00251 0.00000 0.08092 0.00206 0.00000HELLER_SILENCED_BY_METHYLATION_UP
0.00000 0.00000 0.00000 0.00000 0.00001 0.00059ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00000 0.00061 0.00000 0.11599 0.00058 0.00029ZHU_CMV_8_HR_UP
0.00000 0.00000 0.00020 0.01454 0.00704 0.00440NCI_IL23PATHWAY
0.00000 0.00018 0.00000 0.18998 0.08643 0.00253SMID_BREAST_CANCER_LUMINAL_B_DN
0.00269 0.00000 0.00012 0.00059 0.01590 0.03822ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00022 0.00000 0.00000 0.00000 0.00008SANA_TNF_SIGNALING_UP
0.00000 0.00004 0.00000 0.00313 0.01920 0.00000FOSTER_INFLAMMATORY_RESPONSE_LPS_UP
0.03408 0.02501 0.00223 0.06063 0.15750 0.02953XU_HGF_TARGETS_INDUCED_BY_AKT1_6HR
0.00000 0.00000 0.00000 0.00145 0.08932 0.00000VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.00000 0.00252 0.00000 0.00925 0.04935 0.00000LIAN_LIPA_TARGETS_3M
0.00000 0.06209 0.00000 0.12696 0.01801 0.00209KEGG_CHEMOKINE_SIGNALING_PATHWAY
0.00175 0.00109 0.00022 0.00000 0.00364 0.01274GEISS_RESPONSE_TO_DSRNA_UP
0.01044 0.00200 0.00252 0.01719 0.00700 0.05665KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY
0.00024 0.01449 0.00012 0.12825 0.04491 0.00128BIOCARTA_GRANULOCYTES_PATHWAY
0.00000 0.00272 0.00000 0.10946 0.00545 0.00032NCI_IL12_2PATHWAY
0.00000 0.00006 0.00000 0.11528 0.01035 0.00000HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN
0.00053 0.03630 0.00083 0.01057 0.14609 0.06440ZHU_CMV_ALL_UP
0.00000 0.01680 0.00000 0.01658 0.00443 0.00866KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00001 0.00037 0.00009 0.00000 0.09323 0.00033GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00000 0.18489 0.00001 0.10547 0.00108 0.03067BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP
0.02259 0.01466 0.00056 0.07335 0.01954 0.13160SMID_BREAST_CANCER_RELAPSE_IN_PLEURA_DN